Varenicline: An α4β2 Nicotinic Receptor Partial Agonist for Smoking Cessation

Coe, Jotham W., Brooks, Paige R., Vetelino, Michael G., Wirtz, Michael C., Arnold, Eric P., Huang, Jianhua, Sands, Steven B., Davis, Thomas I. +13 more·2005·Journal of Medicinal Chemistry

DOI 10.1021/jm050069n

Cited by (960)

Items 501–600 of 960

Synthesis and biological evaluation of novel hybrids of highly potent and selective α4β2-Nicotinic acetylcholine receptor (nAChR) partial agonists
Han-Kun Zhang, Jason Brek Eaton, Allison Fedolak, Hendra Gunosewoyo, Oluseye K. Onajole, Dani Brunner, Ronald J. Lukas, Li-Fang Yu, Alan P. Kozikowski · 2016 · European Journal of Medicinal Chemistry
Therapeutic concentrations of varenicline in the presence of nicotine increase action potential firing in human adrenal chromaffin cells
Arik J. Hone, J. Michael McIntosh, Lola Rueda‐Ruzafa, J. Passas, Cristina De Castro Guerín, Jesús Blázquez, Carmen González Enguita, Almudena Albillos · 2016 · Journal of Neurochemistry
Synthesis of tetrahydro-3-benzazepines
Meng‐Yang Chang, Chieh‐Kai Chan, Shin‐Ying Lin, Ru‐Ting Hsu · 2012 · Tetrahedron
Methadone’s effect on nAChRs—a link between methadone use and smoking?
Reeta Talka, Raimo K. Tuominen, Outi Salminen · 2015 · Biochemical Pharmacology
Chapter 32 To Market, To Market – 2006
Shridhar G. Hegde, Michelle A. Schmidt · 2007 · Annual reports in medicinal chemistry
Synthesis and activity of substituted carbamates as potentiators of the α4β2 nicotinic acetylcholine receptor
Stephanie K. Springer, Katrina S. Woodin, Virginia M. Berry, Alessandro A. Boezio, Lei Cao, Kristie Clarkin, Jean-Christophe Harmange, Markus Hierl, Johannes Knop, Annika B. Malmberg et al. · 2008 · Bioorganic & Medicinal Chemistry Letters
Pharmacokinetics of cytisine after single intravenous and oral administration in rabbits
Henri Angel Astroug, Rumyana Simeonova, L. Kassabova, N Danchev, Dobrin Avramov Svinarov · 2010 · Interdisciplinary Toxicology
CNS Drug Development
Sheldon Preskorn · 2014 · Journal of Psychiatric Practice
Synthesis, Nicotinic Acetylcholine Receptor Binding, and Antinociceptive Properties of 2′-Fluoro-3′-(substituted pyridinyl)-7-deschloroepibatidine Analogues
Pauline W. Ondachi, Ana H. Castro, Jakub Bartkowiak, Charles W. Luetje, Mohamad Imad Damaj, S. Wayne Mascarella, Hernán A. Navarro, Frank Ivy Carroll · 2014 · Journal of Medicinal Chemistry
Improved treatment of nicotine addiction and emerging pulmonary drug delivery
Islam · 2012 · Drug Discoveries & Therapeutics
The 3,7-diazabicyclo[3.3.1]nonane scaffold for subtype selective nicotinic acetylcholine receptor (nAChR) ligands. Part 1: The influence of different hydrogen bond acceptor systems on alkyl and (hetero)aryl substituents
Christoph Eibl, Isabelle Tomassoli, Lenka Munoz, Clare A. Stokes, Roger L. Papke, Daniela Gündisch · 2013 · Bioorganic & Medicinal Chemistry
Secondary Ammonium Agonists Make Dual Cation-π Interactions in α4β2 Nicotinic Receptors
Michael R. Post, Gabrielle S. Tender, Henry A. Lester, Dennis A. Dougherty · 2017 · eNeuro
The effectiveness of Cytisine versus Nicotine Replacement Treatment for smoking cessation in the Russian Federation
João Maurício Castaldelli-Maia, Silvia Saboia Martins, Natalie K. Walker · 2018 · International Journal of Drug Policy
Cytisine versus varenicline for smoking cessation for Māori (the indigenous people of New Zealand) and their extended family: protocol for a randomized non‐inferiority trial
Natalie K. Walker, Barry D. Smith, Joanne Barnes, Marjolein E. A. Verbiest, Tomasz Kurdziel, Varsha Parag, Subhash Pokhrel, Chris Bullen · 2018 · Addiction
Revisiting autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) mutations in the nicotinic acetylcholine receptor reveal an increase in efficacy regardless of stochiometry
Dinesh C. Indurthi, Taima Qudah, Vivian W. Y. Liao, Philip Kiær Ahring, T. Lewis, Thomas Balle, Mary Chebib, Nathan L. Absalom · 2018 · Pharmacological Research
Varenicline aggravates atherosclerotic plaque formation in nicotine-pretreated ApoE knockout mice due to enhanced oxLDL uptake by macrophages through downregulation of ABCA1 and ABCG1 expression
Mitsuhisa Koga, Yuki Kanaoka, Mana Okamoto, Yuki Nakao, Koshun Inada, Saki Takayama, Yasufumi Kataoka, Atsushi Yamauchi · 2019 · Journal of Pharmacological Sciences
Effect of smoking cessation on sexual functions in men aged 30 to 60 years
Mehmet Oğuz Şahin, Volkan Şen, Gazi Gündüz, Oktay Üçer · 2020 · International braz j urol
Comparison of the effects of bupropion on nicotinic receptor-evoked [3H]dopamine release from rat striatal synaptosomes and slices
Nimish Sidhpura, Peter H. Redfern, Susan Wonnacott · 2007 · European Journal of Pharmacology
Varenicline: progress in smoking cessation treatment
Elbert D. Glover, Jessica Miller Rath · 2007 · Expert Opinion on Pharmacotherapy
▼Varenicline for smoking cessation
BMJ Publishing Group Ltd · 2008 · Drug and Therapeutics Bulletin
Varenicline enhances recognition memory via α7 nicotinic acetylcholine receptors in the medial prefrontal cortex in male mice
Hirohito Esaki, Satoshi Deyama, Shoma Izumi, Ayano Katsura, Keisuke Nishikawa, Naoya Nishitani, Katsuyuki Kaneda · 2023 · Neuropharmacology
Cytisine for smoking cessation: A 40-day treatment with an induction period
Biagio Tinghino, Salvatore Cardellicchio, Flavia Corso, Chiara Cresci, Victoria Pittelli, Rosastella Principe, Licia Siracusano, Giovanni Zelano, Vincenzo Zagà, Maria Sofia Cattaruzza · 2024 · Tobacco Prevention & Cessation
Novel liquid chromatographic methods for the determination of varenicline tartrate
Ramzia Ismail El-Bagary, Nisreen F. Abo-Talib, Marwa A. El-Wahab Mohamed · 2015 · Talanta
Chemistry and Pharmacological Studies of 3-Alkoxy-2,5-Disubstituted-Pyridinyl Compounds as Novel Selective α4β2 Nicotinic Acetylcholine Receptor Ligands That Reduce Alcohol Intake in Rats
Yong Liu, Janell R. Richardson, Thao Phuong Tran, Nour Al‐Muhtasib, Teresa Xie, Venkata Mahidhar Yenugonda, Hannah G. Sexton, Amir H. Rezvani, Edward D. Levin, Niaz Sahibzada et al. · 2013 · Journal of Medicinal Chemistry
IUPHAR-review: The integration of classic psychedelics into current substance use disorder treatment models
David B. Yaden, Andrea P. Berghella, Peter S. Hendricks, Mary Elizabeth Yaden, Michael Levine, Julia Sarah Rohde, Sandeep Manel Nayak, Matthew W. Johnson, Albert Garcia‐Romeu · 2023 · Pharmacological Research
Administration of the nicotinic acetylcholine receptor agonists ABT-089 and ABT-107 attenuates the reinstatement of nicotine-seeking behavior in rats
Alycia M. Lee, Adrian C. Arreola, Blake A. Kimmey, Heath D. Schmidt · 2014 · Behavioural Brain Research
The safety of treatments for tobacco use disorder
Melissa A. Little, Jon O. Ebbert · 2015 · Expert Opinion on Drug Safety
Varenicline impairs extinction and enhances reinstatement across repeated cycles of nicotine self-administration in rats
Claire L. Macnamara, Nathan M. Holmes, Reginald Frederick Westbrook, Kelly J. Clemens · 2016 · Neuropharmacology
Pd-catalyzed arylation of linear and angular spirodiamine salts under aerobic conditions
Sean W. Reilly, Nikaela W. Bryan, Robert H. Mach · 2016 · Tetrahedron Letters
The nicotinic receptor drug sazetidine-A reduces alcohol consumption in mice without affecting concurrent nicotine consumption
Jillienne C. Touchette, Jamie J Maertens, Margaret M Mason, Kyu Y. O’Rourke, Anna M. Lee · 2018 · Neuropharmacology
Brain Nicotinic Receptors as Emerging Targets for Drug Addiction
Shafiqur Rahman · 2011 · Progress in molecular biology and translational science
New medications development for smoking cessation
Dana Lengel, Paul J. Kenny · 2023 · Addiction Neuroscience
How is Membrane Permeation of Small Ionizable Molecules Affected by Protonation Kinetics?
Jonathan J. Harris, Christophe J. Chipot, Benoı̂t Roux · 2024 · The Journal of Physical Chemistry B
Varenicline Reduces Alcohol Intake During Repeated Cycles of Alcohol Reaccess Following Deprivation in Alcohol‐Preferring (P) Rats
Janice C. Froehlich, Emily R. Nicholson, Julian E. Dilley, Nick J. Filosa, Logan C. Rademacher, Teal N. Smith · 2017 · Alcoholism Clinical and Experimental Research
Levo-tetrahydropalmatine inhibits α4β2 nicotinic receptor response to nicotine in cultured SH-EP1 cells
Yuanbing Huang, Zegang Ma, Chao Jun Zheng, K. Xiao-kuang, Devin H. Taylor, Ming Gao, Ronald J. Lukas, Jie Wu · 2021 · Acta Pharmacologica Sinica
Gestational ethanol exposure impairs motor skills in female mice through dysregulated striatal dopamine and acetylcholine function
Sebastiano Bariselli, Yolanda Mateo, Noa Reuveni, David M. Lovinger · 2023 · Neuropsychopharmacology
Stereoselective Synthesis and In Vivo Evaluation of the Analgesic Activity of Polysubstituted Bispidines
Aurélie Plas, Fabien Marchand, Alain Eschalier, Yves Troin, Pierre Chalard · 2012 · European Journal of Organic Chemistry
Depressive Symptoms Among Patients Receiving Varenicline and Bupropion for Smoking Cessation
Arthur S. Hong, Muhamad Y. Elrashidi, Darrell R. Schroeder, Jon O. Ebbert · 2014 · Journal of Substance Abuse Treatment
Preclinical and clinical research on the discriminative stimulus effects of nicotine
Mohammed C. Shoaib, Kenneth A. Perkins · 2020 · Neuropharmacology
Preventive effect of varenicline on impairment of endothelial function in cerebral vessels induced by acute smoking in rats
Mami Iida, Hiroki Iida, Motoyasu Takenaka, Kumiko Tanabe, Kenji Iwata · 2012 · Journal of Anesthesia
Pharmacokinetics of the Novel Nicotinic Receptor Antagonist N,N′-Dodecane-1,12-diyl-bis-3-picolinium Dibromide in the Rat
Zaineb A.F. Albayati, Linda P. Dwoskin, Peter Anthony Crooks · 2008 · Drug Metabolism and Disposition
miRNAome analysis of the mammalian neuronal nicotinic acetylcholine receptor gene family
Eric M. Hogan, Alison P. Casserly, Michael D. Scofield, Zhongming Mou, Rubing Zhao-Shea, Chris W. Johnson, Andrew R. Tapper, Paul D Gardner · 2014 · RNA
Pharmacological treatments for tobacco dependence
K.O. Fagerström, Carlos Andrés Jimenez-Ruiz · 2008 · European Respiratory Review
Inhibition of glycine transporter 1 attenuates nicotine- but not food-induced cue-potentiated reinstatement for a response previously paired with sucrose
Jason M. Uslaner, Jason T. Drott, Steven S. Sharik, Cory R. Theberge, Cyrille Sur, Zhizhen Zeng, David L. Williams, Pete H. Hutson · 2009 · Behavioural Brain Research
Discriminative Stimulus Properties of S(−)-Nicotine: “A Drug for All Seasons”
John A. Rosecrans, Richard Young · 2017 · Current topics in behavioral neurosciences
Varenicline Targets the Reinforcing-Enhancing Effect of Nicotine on Its Associated Salient Cue During Nicotine Self-administration in the Rat
Vernon Garcia‐Rivas, Jean-François Fiancette, Nazzareno Cannella, María Carbo‐Gas, Prisca Renault, Jessica Tostain, Véronique Deroche‐Gamonet · 2019 · Frontiers in Behavioral Neuroscience
Varenicline, the clinically effective smoking cessation agent, restores probabilistic response reversal performance during withdrawal from nicotine
Anne E. Jackson, Sarah Silk, Yazead Buhidma, Mohammed C. Shoaib · 2016 · Addiction Biology
Targeting Reward-Relevant Nicotinic Receptors in the Discovery of Novel Pharmacotherapeutic Agents to Treat Tobacco Dependence
Linda P. Dwoskin, Marharyta Pivavarchyk, B. Matthew Joyce, Nichole M. Neugebauer‎, Guangrong Zheng, Zhenfa Zhang, Michael Thomas Bardo, Peter Anthony Crooks · 2008 · Nebraska Symposium on Motivation/The Nebraska symposium on motivation
Evaluation of structurally diverse neuronal nicotinic receptor ligands for selectivity at the α6∗ subtype
Scott R. Breining, Merouane Bencherif, Sharon R. Grady, Paul Whiteaker, Michael J. Marks, Charles R. Wageman, Henry A. Lester, Daniel Yohannes · 2009 · Bioorganic & Medicinal Chemistry Letters
The effect of varenicline on heart rate variability in healthy smokers and nonsmokers
Hasan Arı, Nuran Celiloğlu, Selma Arı, Selvi Coşar, Kubra Doğanay, Tahsin Bozat · 2011 · Autonomic Neuroscience
Possible Involvement of Endogenous Opioid System Located Downstream of α7 Nicotinic Acetylcholine Receptor in Mice With Physical Dependence on Nicotine
Keiko Ueno, Norikazu Kiguchi, Yuka Kobayashi, Fumihiro Saika, Naoki Wakida, Chizuko Yamamoto, Takehiko Maeda, Masanobu Ozaki, Shiroh Kishioka · 2013 · Journal of Pharmacological Sciences
Electron ionization mass spectral study of selected N ‐amide and N ‐alkyl derivatives of cytisine
Anna K. Przybył, Wiesław Prukała, Dariusz Kikut‐Ligaj · 2007 · Rapid Communications in Mass Spectrometry
Pharmacological Effects of Nicotine on Norepinephrine Metabolism in Rat Brown Adipose Tissue: Relevance to Nicotinic Therapies for Smoking Cessation
Dominique Brees, Michael R. Elwell, Francis David Tingley, Steven B. Sands, Amy B. Jakowski, Amy C. Shen, Jenny Cai, Martin B. Finkelstein · 2008 · Toxicologic Pathology
Anxiety-depressive Symptoms in Patients with Chronic Obstructive Pulmonary Disease (COPD) and Impact on Outcome
Osama M Gado Lamia A Basiony · 2015 · Journal of Depression & Anxiety
Experimental studies of charge density distribution in the crystals of cytisine and N-methylcytisine. Inside the Fake Tobacco
Agata Owczarzak, Anita M. Grześkiewicz, Maciej Kubicki · 2017 · Structural Chemistry
Understanding the implications of the biobehavioral basis of nicotine addiction and its impact on the efficacy of treatment
Nikki Bozinoff, Bernard Le Foll · 2018 · Expert Review of Respiratory Medicine
Role of CYP2B6 pharmacogenomics in bupropion-mediated smoking cessation
Andrew Xuan Vinh Tran, R COOPERDEHOFF, Sheeba Varghese Gupta · 2018 · Journal of Clinical Pharmacy and Therapeutics
Administration of N-acetylcysteine Plus Acetylsalicylic Acid Markedly Inhibits Nicotine Reinstatement Following Chronic Oral Nicotine Intake in Female Rats
Marı́a Elena Quintanilla, Paola Morales, Fernando E. Ezquer, Marcelo Ezquer, Mario Herrera‐Marschitz, Yedy Israel · 2021 · Frontiers in Behavioral Neuroscience
Acute generalized exanthematous pustulosis caused by varenicline
A Duparc, P. Gosset, J Caron, Audrey Lasek, P. Modiano · 2009 · Journal of the European Academy of Dermatology and Venereology
Pregnancy Outcome after Varenicline Exposure in the First Trimester
Yusuf Cem Kaplan, Nihal Olgaç Dündar, Burcu Kasap, Barış Karadas · 2014 · Case Reports in Obstetrics and Gynecology
An efficient synthesis of varenicline
Srinivas Pasikanti, Devarapu Srinivasa Reddy, B. Venkatesham, Praveen Kumar Dubey, Javed Iqbal M, Parthasarathi Das · 2009 · Tetrahedron Letters
Varenicline is a smoking cessation drug that blocks alveolar expansion in mice intratracheally administrated porcine pancreatic elastase
Mitsuhisa Koga, Yuki Kanaoka, Tetsushi Tashiro, Nagisa Hashidume, Yasufumi Kataoka, Atsushi Yamauchi · 2018 · Journal of Pharmacological Sciences
More than Smoke and Patches: The Quest for Pharmacotherapies to Treat Tobacco Use Disorder
Megan Jo Moerke, Lance Richard McMahon, Jenny L. Wilkerson · 2020 · Pharmacological Reviews
Smoking Hazards and Cessation
Neal L. Benowitz, Paul G. Brunetta · 2010 · Elsevier eBooks
Nicotinic Acetylcholine Receptor Alterations in Autism Spectrum Disorders – Biomarkers and Therapeutic Targets
René Anand, A. Stephanie, Gerald D. Ponath, Jordan I., Muhammad Ismail Nasir, B. Susan · 2011 · InTech eBooks
A novel series of [3.2.1] azabicyclic biaryl ethers as α3β4 and α6/4β4 nicotinic receptor agonists
John A. Lowe III, Shari L. DeNinno, Jotham W. Coe, Lei Zhang, Scot Mente, Raymond S Hurst, Robert J. Mather, Karen M. Ward, Alka Shrikhande, Hans Rollema et al. · 2010 · Bioorganic & Medicinal Chemistry Letters
Maximizing Smoking Cessation in Clinical Practice: Pharmacologic and Behavioral Interventions
Mitchell A. Nides, Scott James Leischow, Linda Sarna, Sarah E. Evans · 2007 · Preventive Cardiology
Recent advances in gene manipulation and nicotinic acetylcholine receptor biology
Anne Tammimäki, William J. Horton, Jerry A. Stitzel · 2011 · Biochemical Pharmacology
The impact of three weeks of pre-quit varenicline on reinforcing value and craving for cigarettes in a laboratory choice procedure
Schuyler C. Lawson, Julie C. Gass, Robert K. Cooper, Sarah Tonkin, Craig R. Colder, Martin Christopher Mahoney, Stephen T. Tiffany, Larry W. Hawk · 2020 · Psychopharmacology
Iridium-catalysed synthesis of C,N,N-cyclic azomethine imines enables entry to unexplored nitrogen-rich 3D chemical space
Yaseen A. Almehmadi, Jack McGeehan, Nandini J. Guzman, Kirsten E. Christensen, Ken Yamazaki, Darren J. Dixon · 2024 · Nature Synthesis
Fatality following a suicidal overdose with varenicline
Christophe Pol Stove, Els A. De Letter, Michel H A Piette, Willy E. Lambert · 2012 · International Journal of Legal Medicine
Pharmacotherapy for tobacco cessation: Nicotine agonists, antagonists, and partial agonists
Maher Karam‐Hage, Paul M. Cinciripini · 2007 · Current Oncology Reports
Smoking Cessation Interventions for Lung Cancer Patients
Kristin Carson‐Chahhoud, Zafar Ahmad Usmani, Thomas A. Robertson, Satya Mysore, Malcolm P Brinn · 2013 · Lung Cancer Management
Current Treatment Options in Smoking Cessation
Dominique Crain, Abid Bhat · 2010 · Hospital Practice
Clinical experience of varenicline for smoking cessation
Jae‐Woo Jung, Eun Ju Jeon, Jae Gyu Kim, Suh‐Yoon Yang, Jae Chol Choi, Jong Wook Shin, In Won Park, Byoung Whui Choi, Don‐Kyu Kim, Jae Yeol Kim · 2009 · The Clinical Respiratory Journal
Immediate release tablet formulation of varenicline salicylate and comparative pharmacokinetic study in human volunteers
Seong Shin Kwak, Eun Seok Lee, Ho Yub Yoon, Chang Hyun Kim, Yoon Tae Goo, Myung Joo Kang, Sang Kil Lee, Bong Sang Lee, Hong Ryeol Jeon, Chang Hyun Oh et al. · 2018 · Drug Design Development and Therapy
New Rigid Nicotine Analogues, Carrying a Norbornane Moiety, Are Potent Agonists of α7 and α3* Nicotinic Receptors
Dina Manetti, Aleksandra I. Garifulina, Gianluca Bartolucci, Carla Bazzicalupi, Cristina Bellucci, Niccolò Chiaramonte, Silvia Dei, Lorenzo Di Cesare Mannelli, Carla Ghelardini, Paola Gratteri et al. · 2019 · Journal of Medicinal Chemistry
The effects of varenicline on methamphetamine self-administration and drug-primed reinstatement in male rats
Steven T. Pittenger, Scott T. Barrett, Shinnyi Chou, Rick A. Bevins · 2016 · Behavioural Brain Research
The influence of acute varenicline administration on smoking and eating behavior in humans
William Walton Stoops, Andrea Rae Vansickel, Paul E.A. Glaser, Craig R. Rush · 2008 · Pharmacology Biochemistry and Behavior
Improvement of Restless Legs Syndrome by Varenicline as Antismoking Treatment
Andrea Romigi, Giuseppe Vitrani · 2013 · Journal of Clinical Sleep Medicine
Stress Degradation Studies on Varenicline Tartrate and Development of a Validated Stability-Indicating HPLC Method
Sudhakar S. Pujeri · 2011 · Scientia Pharmaceutica
Varenicline improves motor and cognitive symptoms in early Huntington’s disease
Ailsa L. McGregor, Jo Dysart, Malcolm Drummond Tingle, Bruce Russell, Robert R. Kydd, Gregory Finucane · 2016 · Neuropsychiatric Disease and Treatment
Pseudo three-component approach to coumarin-annulated azepines: synthesis of coumarin[3,4-b]azepines
Kiran B. Manjappa, Yu‐Ting Peng, Teau‐Jiuan Liou, Ding‐Yah Yang · 2017 · RSC Advances
Natural products as tools for studies of ligand‐gated ion channels
Kristian Strømgaard · 2005 · The Chemical Record
Preparation of novel azabicyclic amines and α7 nicotinic acetylcholine receptor activity of derived aryl amides
Daniel P. Walker, Brad A. Acker, E. Jon Jacobsen, Donn G. Wishka · 2008 · Journal of Heterocyclic Chemistry
SMOKING AS A RISK FACTOR FOR CARDIOVASCULAR AND CEREBROVASCULAR DISEASES: PREVALENCE, IMPACT ON PROGNOSIS, POSSIBLE SMOKING CESSATION STRATEGIES AND THEIR EFFECTIVENESS. Part 2. Advantages of quitting smoking. Strategies to quit smoking
Ol'ga Dmitrievna Ostroumova, Копченов Иван Иванович, Tatiana F. Guseva · 2018 · Rational Pharmacotherapy in Cardiology
Año SEPAR 2007: Año para la Prevención y el Control del Tabaquismo
Carlos Andrés Jiménez Ruiz, Ángela Ramos Pinedo, Juan Antonio Riesco Miranda, Julio Ancochea · 2007 · Archivos de Bronconeumología
The Persistent Challenge of Developing Addiction Pharmacotherapies
Sarah E. Swinford-Jackson, Charles P. O’Brien, Paul J. Kenny, Louk J. M. J. Vanderschuren, Ellen M. Unterwald, Robert Christopher Pierce · 2020 · Cold Spring Harbor Perspectives in Medicine
The smoking cessation drug varenicline improves deficient P20–N40 inhibition in DBA/2 mice
Kristin M. Wildeboer, Karen E. Stevens · 2011 · Pharmacology Biochemistry and Behavior
Specificity of Varenicline in Blocking Mesolimbic Circuit Activation to Natural and Drug Rewards
Nitsan Goldstein, Jamie R. E. Carty, J. Nicholas Betley · 2021 · Neuroscience
Update on smoking cessation therapies
Deirdre A. Glynn, John F. Cryan, Pauline Kent, Robert A. Flynn, Marcus Peter Kennedy · 2009 · Advances in Therapy
Synthesis and Behavioral Studies of Chiral Cyclopropanes as Selective α4β2-Nicotinic Acetylcholine Receptor Partial Agonists Exhibiting an Antidepressant Profile. Part III
Oluseye K. Onajole, Gian Paolo Vallerini, Jason Brek Eaton, Ronald J. Lukas, Dani Brunner, Barbara J. Caldarone, Alan P. Kozikowski · 2016 · ACS Chemical Neuroscience
The effects of varenicline on lumbar spinal fusion in a rat model
Jason R. Kang, Juliane D. Glaeser, Brian A. Karamian, Linda E.A. Kanim, Zachary M. NaPier, Jayme Carolynn Burket Koltsov, Timothy Thio, Khosrowdad Salehi, Hyun W. Bae, Ivan Cheng · 2019 · The Spine Journal
Quantitative Molecular Imaging of Neuronal Nicotinic Acetylcholine Receptors in the Human Brain with A-85380 Radiotracers
Shahrdad Lotfipour, Mark A. Mandelkern, Arthur L. Brody · 2011 · Current Medical Imaging Formerly Current Medical Imaging Reviews
Computational studies of novel carbonyl-containing diazabicyclic ligands interacting with α4β2 nicotinic acetylcholine receptor (nAChR) reveal alternative binding modes
David C. Kombo, Anatoly A. Mazurov, Jon‐Paul Strachan, Merouane Bencherif · 2013 · Bioorganic & Medicinal Chemistry Letters
Update on the Pharmacologic Therapy for Chronic Obstructive Pulmonary Disease
Nicola Alexander Hanania, Amir Sharafkhaneh · 2007 · Clinics in Chest Medicine
Comparison of the Effectiveness of Varenicline, Extended-Release Bupropion and Nicotine Replacement Therapy on The Success and the Maintenance of a Smoking Cessation Program
Selma Bozkurt Zincir, Serkan Zincir, Esra Kaymak, Esra Aydın Sünbül · 2013 · Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology
Partial agonists for α4β2 nicotinic receptors stimulate dopaminergic neuron firing with relatively enhanced maximal effects
Ying Chen, Lisa M. Broad, Keith Geoffrey Phillips, Ruud Zwart · 2011 · British Journal of Pharmacology
Randomized Clinical Trials Investigating Innovative Interventions for Smoking Cessation in the Last Decade
Marie N. S. Gendy, Christine Ibrahim, Matthew E. Sloan, Bernard Le Foll · 2019 · Handbook of experimental pharmacology
Nephrotoxic effects of varenicline as the most effective drug used for smoking cessation: a preliminary experimental study
Akif Koç, Haydar Ali Erken, Fatma Emel Koçak, Arzu Yay, Aydın Güçlü, Erhan Sarı, Hasan Şimşek, Gözde Özge Önder, Osman Genç · 2015 · International Urology and Nephrology