Varenicline: An α4β2 Nicotinic Receptor Partial Agonist for Smoking Cessation

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Items 401–500 of 960

1. Effect of varenicline on aspects of inhibitory control in smokers
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2. Insertion of Allenes into the Pd–C Bond of Ortho-Palladated Primary Arylamines of Biological Relevance: Phenethylamine, Phentermine, ( l )-Phenylalanine Methyl Ester, and ( l )-Tryptophan Methyl Ester. Synthesis of Tetrahydro-3-benzazepines and Their Salts
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3. Varenicline-Induced Elevation of Dopamine in Smokers: A Preliminary [11C]-(+)-PHNO PET Study
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4. Combined administration of varenicline and bupropion produces additive effects on accumbal dopamine and abolishes the alcohol deprivation effect in rats
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5. Chronic treatment with varenicline changes expression of four nAChR binding sites in mice
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6. Nerve agent exposure elicits site-specific changes in protein phosphorylation in mouse brain
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7. Varenicline Blocks 2*-nAChR-Mediated Response and Activates 4*-nAChR-Mediated Responses in Mice In Vivo
   Ortiz, N. C., O'Neill, H. C., Marks, M. J., Grady, S. R. · 2012 · Nicotine & Tobacco Research
8. The Relationship of Varenicline Agonism of α4β2 Nicotinic Acetylcholine Receptors and Nicotine-Induced Dopamine Release in Nicotine-Dependent Humans
   Mary Elizabeth McCaul, Gary S. Wand, Hiroto Kuwabara, Robert F. Dannals, Dean Foster Wong, Xiaoqiang Xu · 2019 · Nicotine & Tobacco Research
9. Nicotinic Ligands Modulate Ethanol-Induced Dopamine Function in Mice
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10. Region‐specific effects of N , N ′‐dodecane‐1,12‐diyl‐bis‐3‐picolinium dibromide on nicotine‐induced increase in extracellular dopamine in vivo
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11. Pyridine analogs of (−)-cytisine and varenicline: cholinergic receptor probes
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12. Sex differences in attenuation of nicotine reinstatement after individual and combined treatments of progesterone and varenicline
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13. Chapter 4 Case History: Chantix™/Champix™ (Varenicline Tartrate), a Nicotinic Acetylcholine Receptor Partial Agonist as a Smoking Cessation Aid
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14. Real World Study to Evaluate the Effectiveness of Varenicline and Cognitive-Behavioural Interventions for Smoking Cessation
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15. The synthesis and nicotinic binding activity of (±)-epiquinamide and (±)-C(1)-epiepiquinamide
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16. The Effect of Varenicline on the Neural Processing of Fearful Faces and the Subjective Effects of Alcohol in Heavy Drinkers
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17. A Flexible Strategy for the Synthesis of Tri‐ and Tetracyclic Lupin Alkaloids: Synthesis of (+)‐Cytisine, (±)‐Anagyrine, and (±)‐Thermopsine
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18. Multiple binding sites in the nicotinic acetylcholine receptors: An opportunity for polypharmacolgy
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19. Variations in Binding Amongst Several Agonists at Two Stoichiometries of the Neuronal, α4β2 Nicotinic Receptor
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20. Varenicline for smoking cessation
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21. Building polyfunctional piperidines: a stereoselective strategy of a three-component Mannich reaction inspired by biosynthesis and applications in the synthesis of natural alkaloids (+)-241D; (−)-241D; isosolenopsin A and (−)-epimyrtine
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22. Effects of varenicline therapy in combination with advanced behavioral support on smoking cessation and quality of life in inpatients with acute exacerbation of COPD, bronchial asthma, or community-acquired pneumonia: A prospective, open-label, preference-based, 52-week, follow-up trial
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23. Indolizidine (−)-235B′ and related structural analogs: Discovery of nicotinic receptor antagonists that inhibit nicotine-evoked [3H]dopamine release
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24. Neuropsychiatric disturbance after initiation of varenicline in a patient with a history of alcohol abuse and major depression
    Pejman Pirmoradi, Susan Roshan, Sofia S. Nadeem · 2008 · American Journal of Health-System Pharmacy
25. Synthesis of Benzomorphan Analogues by Intramolecular Buchwald–Hartwig Cyclization
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26. Current approaches to pharmacotherapy for smoking cessation
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27. Neurobiological Bases of Cue- and Nicotine-induced Reinstatement of Nicotine Seeking: Implications for the Development of Smoking Cessation Medications
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28. Cyclopentadiene: The Impact of Storage Conditions on Thermal Stability
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29. A cost-effectiveness model of smoking cessation based on a randomised controlled trial of varenicline versus placebo in patients with chronic obstructive pulmonary disease
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30. Cytisine's Potential to Be Used as a Traditional Healing Method to Help Indigenous People Stop Smoking: A Qualitative Study With M ori
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31. Cognition as a therapeutic target in late-life depression: Potential for nicotinic therapeutics
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32. Synthesis and activity of substituted heteroaromatics as positive allosteric modulators for α4β2α5 nicotinic acetylcholine receptors
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33. Cytisine modulates chronic voluntary ethanol consumption and ethanol-induced striatal up-regulation of ΔFosB in mice
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34. Rhodium-Catalyzed Diastereoselective C–H Activation/[4 + 2] Annulation of α,β-Unsaturated Amides with Bicyclic Alkenes
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35. Docking studies of benzylidene anabaseine interactions with α7 nicotinic acetylcholine receptor (nAChR) and acetylcholine binding proteins (AChBPs): Application to the design of related α7 selective ligands
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36. Development of an anti-cotinine vaccine to potentiate nicotine-based smoking cessation strategies
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37. Deconstructing cytisine: The syntheses of (±)-cyfusine and (±)-cyclopropylcyfusine, fused ring analogs of cytisine
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38. Multiple nicotine training doses in mice as a basis for differentiating the effects of smoking cessation aids
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39. Varenicline and nicotine enhance GABAergic synaptic transmission in rat CA1 hippocampal and medial septum/diagonal band neurons
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40. Smoking cessation readiness: Are your patients ready to quit?
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41. Clinical Neuroscience of Addiction: Similarities and Differences Between Alcohol and Other Drugs
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42. Varenicline for tobacco dependence: panacea or plight?
    Jill M. Williams, Michael B. Steinberg, Marc L. Steinberg, Kunal K. Gandhi, Rajiv Ulpe, Jonathan Foulds · 2011 · Expert Opinion on Pharmacotherapy
43. Structure activity relationship (SAR) study identifies a quinoxaline urea analog that modulates IKKβ phosphorylation for pancreatic cancer therapy
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44. A divergent approach to highly substituted benzothiepinones and to 2,3-dihydrothieno[2,3-b]thiopyran-4-ones
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45. 7-Azaindole derivatives as potential partial nicotinic agonists
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46. Varenicline modulates ethanol and saccharin consumption in adolescent male and female C57BL/6J mice
    Helen M. Kamens, Constanza P. Silva, Colette Peck, Carley N. Miller · 2017 · Brain Research Bulletin
47. Drugs and genotypes: how pharmacogenetic information could improve smoking cessation treatment
    Anna M. Lee, R. Tyndale · 2006 · Journal of Psychopharmacology
48. Lack of a pharmacokinetic interaction between a new smoking cessation therapy, varenicline, and digoxin in adult smokers
    H. M. Faessel, Aaron H. Burstein, Matthew D. Troutman, Susan A. Willavize, Kevin D. Rohrbacher, D. J. Clark · 2008 · European Journal of Clinical Pharmacology
49. Nicotine and neuronal nicotinic acetylcholine receptors: unraveling the mechanisms of nicotine addiction
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50. Distinctive single-channel properties of α4β2-nicotinic acetylcholine receptor isoforms
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51. Pharmacotherapeutic Management of Nicotine Dependence in Pregnancy
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52. Varenicline use in patients with mental illness: an update of the evidence
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53. The effects of nicotine and cigarette smoke on the monoamine transporters
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54. Differentiating the primary reinforcing and reinforcement-enhancing effects of varenicline
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55. An Unusual Pattern of Ligand-Receptor Interactions for the α7 Nicotinic Acetylcholine Receptor, with Implications for the Binding of Varenicline
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56. An update on the pharmacotherapeutic interventions for smoking cessation
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57. Attenuation of nicotine taking and seeking in rats by the stoichiometry-selective alpha4beta2 nicotinic acetylcholine receptor positive allosteric modulator NS9283
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58. Allosteric modulation of muscarinic receptors in alcohol and substance use disorders
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59. CHRNA4 rs1044396 is associated with smoking cessation in varenicline therapy
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60. Varenicline for tobacco dependence treatment in recovering alcohol-dependent smokers: An open-label pilot study
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61. Efficacy of a dose range of surinabant, a cannabinoid receptor blocker, for smoking cessation: a randomized controlled clinical trial
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62. Varenicline in smoking cessation
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63. The nicotine + alcohol interoceptive drug state: contribution of the components and effects of varenicline in rats
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64. Effect of co-administration of varenicline and antidepressants on extracellular monoamine concentrations in rat prefrontal cortex
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65. The Role of Microglia in Sex- and Region-Specific Blood-Brain Barrier Integrity During Nicotine Withdrawal
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66. A Systematic Review on Drugs Acting as Nicotinic Acetylcholine Receptor Agonists in the Treatment of Dementia
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67. Varenicline effects on cocaine self administration and reinstatement behavior
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68. The effect of varenicline on binge-like ethanol consumption in mice is β4 nicotinic acetylcholine receptor-independent
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69. l-tetrahydropalmatine reduces nicotine self-administration and reinstatement in rats
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70. NAChR α4β2 Subtype and their Relation with Nicotine Addiction, Cognition, Depression and Hyperactivity Disorder
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71. Hesperidin blocks varenicline-aggravated atherosclerotic plaque formation in apolipoprotein E knockout mice by downregulating net uptake of oxidized low-density lipoprotein in macrophages
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72. Simulation and Machine Learning Methods for Ion-Channel Structure Determination, Mechanistic Studies and Drug Design
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73. New Findings on Nicotine Addiction and Treatment
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74. Design, Synthesis and Discovery of Picomolar Selective α4β2 Nicotinic Acetylcholine Receptor Ligands
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75. Reactivity of Eight-Membered Palladacycles Arising from Monoinsertion of Alkynes into the Pd–C bond of Ortho-Palladated Phenethylamines toward Unsaturated Molecules. Synthesis of Dihydro-3-Benzazocinones, N7-amino Acids, N7-amino Esters, and 3-Benzazepines
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76. One-pot synthesis of chiral azetidines from chloroaldehyde and chiral amines
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77. Null mutation of the β2 nicotinic acetylcholine receptor subunit attenuates nicotine withdrawal-induced anhedonia in mice
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78. The effects of varenicline on methamphetamine self-administration and drug-primed reinstatement in female rats
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79. Delayed Varenicline Administration Reduces Inflammation and Improves Forelimb Use Following Experimental Stroke
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80. Varenicline for smoking reduction in smokers not yet ready to quit: A double-blind, proof-of-concept randomized clinical trial
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81. Advances in smoking cessation pharmacotherapy: Non-nicotinic approaches in animal models
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82. Cytisine inhibits the anticonvulsant activity of phenytoin and lamotrigine in mice
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83. Involvement of neuronal β 2 subunit-containing nicotinic acetylcholine receptors in nicotine reward and withdrawal: Implications for pharmacotherapies
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84. Combining intensive practice nurse counselling or brief general practitioner advice with varenicline for smoking cessation in primary care: Study protocol of a pragmatic randomized controlled trial
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85. Single- and Multiple-Dose Pharmacokinetics of the Selective Nicotinic Receptor Partial Agonist, Varenicline, in Healthy Japanese Adult Smokers
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86. Current and Emerging Pharmacotherapeutic Options for Smoking Cessation
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87. Varenicline aggravates plaque formation through α7 nicotinic acetylcholine receptors in ApoE KO mice.
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88. Nicotinic Acetylcholine α4β2 Receptor Regulates the Motivational Effect of Intracranial Self Stimulation Behavior in the Runway Method
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89. Functional Evaluation of Key Interactions Evident in the Structure of the Eukaryotic Cys-Loop Receptor GluCl
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90. Synthesis and evaluation of N1-alkylindole-3-ylalkylammonium compounds as nicotinic acetylcholine receptor ligands
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91. Nicotinic receptor partial agonists modulate alcohol deprivation effect in C57BL/6J mice
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92. Discriminative stimulus and hypothermic effects of some derivatives of the nAChR agonist epibatidine in mice
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93. Translational Research on Nicotine Dependence
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94. Synthesis of Benzazepinones via Intramolecular Cyclization Involving Ketene Iminium Intermediates
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95. Expression of α3β2β4 nicotinic acetylcholine receptors by rat adrenal chromaffin cells determined using novel conopeptide antagonists
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96. The effect of varenicline on the development and expression of nicotine‐induced behavioral sensitization and cross‐sensitization in rats
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97. Decreasing nicotinic receptor activity and the spatial learning impairment caused by the NMDA glutamate antagonist dizocilpine in rats
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98. Synthesis of a cytisine/epibatidine hybrid: a radical approach
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99. Altered spontaneous activity of posterior cingulate cortex and superior temporal gyrus are associated with a smoking cessation treatment outcome using varenicline revealed by regional homogeneity
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100. Smoking Hazards and Cessation
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