The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
In Situ Assembly of Colloidal Particles into Miniaturized Biosensors
Abstract
We show how to create arrays of biosensors by in situ assembly of colloidal particles onto micropatterned electrodes. Latex microspheres from suspension are collected via dielectrophoresis in the micrometer-sized gaps between planar electrodes. The assembled particulate patches are fixed by changing the colloidal interactions to induce coagulation. Immuno-active sites on the latex surfaces bind the target molecules. A direct electric conductivity readout is accomplished after secondary tagging with colloidal gold and its enhancement by silver nucleation. The method holds promise for creating disposable on-chip arrays of highly sensitive miniature sensors for specific proteins, DNA fragments, or other biomolecules.
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Citations
Cites
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Cited by
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Metadata
- Authors
- Velev, O. D., & Kaler, E. W.
- Venue
- Langmuir
- Publisher
- American Chemical Society (ACS)
- Published
- 1999-04-30
- Volume
- 15
- Issue
- 11
- Pages
- 3693-3698
- ISSN
- 0743-7463 (ISSN-L)
- 1520-5827
- OpenAlex
- W2142091096
- Cited by
- 472
- References
- 24
- FWCI
- 11.21
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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