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ABC and SLC Transporter Expression and Pot Substrate Characterization across the Human CMEC/D3 Blood−Brain Barrier Cell Line
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hCMEC/D3 cells constitutively express Pgp/ABCB1, MRP1/ABCC1, and BCRP/ABCG2.
“hCMEC/D3 cells constitutively express several ABC transporters (Carl et al., 2010), like Pgp/ABCB1, MRP1/ABCC1, BCRP/ ABCG2 (Figure 2A).”
From The association of statins plus LDL receptor‐targeted liposome‐encapsulated doxorubicin increases in vitro drug delivery across blood–brain barrier cells (2012) · cites this paper as Carl et al., 2010
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Quantitative targeted absolute proteomics of human blood-brain barrier transporters and receptors
Uchida, Y., Ohtsuki, S., Katsukura, Y., Ikeda, C., Suzuki, T., Kamiie, J., & Terasaki, T. (2011) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2011.07208.x · Cited by 881
The hCMEC/D3 cell line as a model of the human blood brain barrier
Weksler, B., Romero, I. A., & Couraud, P.-O. (2013) · Fluids and Barriers of the CNS · doi:10.1186/2045-8118-10-16 · Cited by 753
Self-citationTransport of Amino Acids Across the Blood-Brain Barrier
Zaragozá, R. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.00973 · Cited by 202
Fazakas, C., Wilhelm, I., Nagyőszi, P., Farkas, A. E., Haskó, J., Molnár, J., Bauer, H., Bauer, H.-C., Ayaydin, F., Dung, N. T. K., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0020758 · Cited by 147
Pinzón‐Daza, M., Garzón, R., Couraud, P., Romero, I., Weksler, B., Ghigo, D., Bosia, A., & Riganti, C. (2012) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2012.02103.x · Cited by 84
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Metadata
- Authors
- Carl, S. M., Lindley, D. J., Couraud, P. O., Weksler, B. B., Romero, I., Mowery, S. A., & Knipp, G. T.
- Affiliations
- Department of Industrial and Physical Pharmacy, School of Pharmacy, Purdue University, West Lafayette, Indiana, Institut Cochin, Université Paris Descartes, CNRS (UMR 8104), Paris, France, Inserm, U567, Paris, France, Medicine Division of Hematology-Oncology, Weill Medical College of Cornell University, New York, New York, and Department of Life Sciences, The Open University, Milton Keynes, U.K.
- Venue
- Molecular Pharmaceutics
- Publisher
- American Chemical Society (ACS)
- Published
- 2010-07-06
- Volume
- 7
- Issue
- 4
- Pages
- 1057-1068
- ISSN
- 1543-8384
- 1543-8392
- PMC
- PMC2914114
- Cited by
- 88
- References
- 1
- Language
- en
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