The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Size and Surface Effects on the MRI Relaxivity of Manganese Ferrite Nanoparticle Contrast Agents
Open accessAbstract
Superparamagnetic MnFe2O4 nanocrystals of different sizes were synthesized in high-boiling ether solvent and transferred into water using three different approaches. First, we applied a ligand exchange in order to form a water soluble polymer shell. Second, the particles were embedded into an amphiphilic polymer shell. Third, the nanoparticles were embedded into large micelles formed by lipids. Although all approaches lead to effective negative contrast enhancement, we observed significant differences concerning the magnitude of this effect. The transverse relaxivity, in particular r2*, is greatly higher for the micellar system compared to the polymer-coated particles using same-sized nanoparticles. We also observed an increase in transverse relaxivities with increasing particle size for the polymer-coated nanocrystals. The results are qualitatively compared with theoretical models describing the dependence of relaxivity on the size of magnetic spheres.
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Cites
Multifunctional polymeric micelles as cancer-targeted, MRI-ultrasensitive drug delivery systems
Nasongkla, N., Bey, E., Ren, J., Ai, H., Khemtong, C., Guthi, J. S., Chin, S.-F., Sherry, A. D., Boothman, D. A., & Gao, J. (2006) · Nano Letters · doi:10.1021/nl061412u · Cited by 1,238
Cited by
Biological applications of magnetic nanoparticles
Colombo, M., Carregal-Romero, S., Casula, M. F., Gutiérrez, L., Morales, M. P., Böhm, I. B., Heverhagen, J. T., Prosperi, D., & Parak, W. J. (2012) · Chemical Society Reviews · doi:10.1039/c2cs15337h · Cited by 1,315
Self-citationPhysical Principles of Nanoparticle Cellular Endocytosis
Zhang, S., Gao, H., & Bao, G. (2015) · ACS Nano · doi:10.1021/acsnano.5b03184 · Cited by 1,103
Lee, N., & Hyeon, T. (2012) · Chem. Soc. Rev. · doi:10.1039/c1cs15248c · Cited by 995
Tromsdorf, U. I., Bruns, O. T., Salmen, S. C., Beisiegel, U., & Weller, H. (2009) · Nano Letters · doi:10.1021/nl902715v · Cited by 396
Self-citationHühn, J., Carrillo-Carrion, C., Soliman, M. G., Pfeiffer, C., Valdeperez, D., Masood, A., Chakraborty, I., Zhu, L., Gallego, M., Yue, Z., et al. (2017) · Chemistry of Materials · doi:10.1021/acs.chemmater.6b04738 · Cited by 283
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Metadata
- Authors
- Tromsdorf, U. I., Bigall, N. C., Kaul, M. G., Bruns, O. T., Nikolic, M. S., Mollwitz, B., Sperling, R. A., Reimer, R., Hohenberg, H., Parak, W. J., Förster, S., Beisiegel, U., Adam, G., & Weller, H.
- Venue
- Nano Letters
- Publisher
- American Chemical Society (ACS)
- Published
- 2007-07-20
- Volume
- 7
- Issue
- 8
- Pages
- 2422-2427
- ISSN
- 1530-6984 (ISSN-L)
- 1530-6992
- OpenAlex
- W1993177238
- Cited by
- 432
- References
- 1
- FWCI
- 13.72
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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