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The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Colchicine-Loaded Lipid Bilayer-Coated 50 nm Mesoporous Nanoparticles Efficiently Induce Microtubule Depolymerization upon Cell Uptake

Cauda, Valentina, Engelke, Hanna, Sauer, Anna, Arcizet, Delphine, Rädler, Joachim, Bein, Thomas·2010·Nano Letters
DOI 10.1021/nl100991w
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Abstract

We report on a one-step assembly route where supported lipid bilayers (SLB) are deposited on functionalized colloidal mesoporous silica (CMS) nanoparticles, resulting in a core-shell hybrid system (SLB@CMS). The supported membrane acts as an intact barrier against the escape of encapsulated dye molecules. These stable SLB@CMS particles loaded with the anticancer drug colchicine are readily taken up by cells and lead to the depolymerization of microtubules with remarkably enhanced efficiency as compared to the same dose of drug in solution.

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Research works printed but not linked: 26

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Metadata

Authors
Cauda, V., Engelke, H., Sauer, A., Arcizet, D., Rädler, J., & Bein, T.
Affiliations
  • Department of Chemistry and Center for NanoScience (CeNS), University of Munich (LMU), Butenandtstrasse 5-13 (E), 81377 Munich, Germany
  • Faculty of Physics and Center for NanoScience (CeNS), University of Munich (LMU), Geschwister-Scholl-Platz 1, 80539 Munich, Germany
Venue
Nano Letters
Publisher
American Chemical Society (ACS)
Published
2010-06-01
Volume
10
Issue
7
Pages
2484-2492
ISSN
  • 1530-6984
  • 1530-6992
DOI
10.1021/nl100991w
Cited by
155
References
2
Language
en

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