The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Electrically Actuatable Smart Nanoporous Membrane for Pulsatile Drug Release
Abstract
We report on the fabrication of electrically responsive nanoporous membrane based on polypyrrole doped with dodecylbenzenesulfonate anion (PPy/DBS) that was electropolymerized on the upper part of anodized aluminum oxide membrane. The membrane has regular pore size and very high pore density. Utilizing a large volume change of PPy/DBS depending on electrochemical state, the pore size was acutated electrically. The actuation of the pores was experimentally confirmed by in situ atomic force microscopy and in situ flux measurement. We also demonstrated successfully pulsatile (or on-demand) drug release by using fluorescently labeled protein as a model drug. Because of a fast switching time (less than 10 s) and high flux of the drugs, this membrane could be used for emergency therapy of angina pectoris and migraine, which requires acute and on-demand drug delivery, and hormone-related disease and metabolic syndrome.
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Cites
Photodegradable Hydrogels for Dynamic Tuning of Physical and Chemical Properties
Kloxin, A. M., Kasko, A. M., Salinas, C. N., & Anseth, K. S. (2009) · Science · doi:10.1126/science.1169494 · Cited by 1,748
Multi-pulse drug delivery from a resorbable polymeric microchip device
Grayson, A. C. R., Choi, I. S., Tyler, B. M., Wang, P. P., Brem, H., Cima, M. J., & Langer, R. (2003) · Nature Materials · doi:10.1038/nmat998 · Cited by 444
Cited by
Nanoporous anodic aluminium oxide: Advances in surface engineering and emerging applications
Md Jani, A. M., Losic, D., & Voelcker, N. H. (2013) · Progress in Materials Science · doi:10.1016/j.pmatsci.2013.01.002 · Cited by 553
Moradi Kashkooli, F., Soltani, M., & Souri, M. (2020) · Journal of Controlled Release · doi:10.1016/j.jconrel.2020.08.012 · Cited by 514
Integrating Artificial Intelligence and Nanotechnology for Precision Cancer Medicine
Adir, O., Poley, M., Chen, G., Froim, S., Krinsky, N., Shklover, J., Shainsky‐Roitman, J., Lammers, T., & Schroeder, A. (2020) · Advanced Materials · doi:10.1002/adma.201901989 · Cited by 496
Liu, Z., Wan, X., Wang, Z. L., & Li, L. (2021) · Advanced Materials · doi:10.1002/adma.202007429 · Cited by 478
El-Sawy, H. S., Al-Abd, A. M., Ahmed, T. A., El-Say, K. M., & Torchilin, V. P. (2018) · ACS Nano · doi:10.1021/acsnano.8b06104 · Cited by 431
Metadata
- Authors
- Jeon, G., Yang, S. Y., Byun, J., & Kim, J. K.
- Venue
- Nano Letters
- Publisher
- American Chemical Society (ACS)
- Published
- 2011-01-31
- Volume
- 11
- Issue
- 3
- Pages
- 1284-1288
- ISSN
- 1530-6984 (ISSN-L)
- 1530-6992
- OpenAlex
- W1978693732
- Cited by
- 218
- References
- 2
- FWCI
- 7.13
- Type
- journal article
- Language
- en
- Open access
- closed
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- Jeon, G., Yang, S. Y., Byun, J., & Kim, J. K. (2011). Electrically Actuatable Smart Nanoporous Membrane for Pulsatile Drug Release. Nano Letters. https://doi.org/10.1021/nl104329y
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