The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.
A Nanostructured Conductive Hydrogels-Based Biosensor Platform for Human Metabolite Detection
Abstract
The development of a scalable, low-cost, and versatile biosensor platform for the sensitive and rapid detection of human metabolites is of great interest for healthcare, pharmaceuticals, and medical science. On the basis of hierarchically nanostructured conducting polymer hydrogels, we designed a flexible biosensor platform that can detect various human metabolites, such as uric acid, cholesterol, and triglycerides. Owing to the unique features of conducting polymer hydrogels, such as high permeability to biosubstrates and rapid electron transfer, our biosensors demonstrate excellent sensing performance with a wide linear range (uric acid, 0.07-1 mM; cholesterol, 0.3-9 mM, and triglycerides, 0.2-5 mM), high sensitivity, low sensing limit, and rapid response time (∼3 s). Given the facile and scalable processability of hydrogels, the proposed conductive hydrogels-based biosensor platform shows great promise as a low-cost sensor kit for healthcare monitoring, clinical diagnostics, and biomedical devices.
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Cites
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Self-citationHighly Sensitive Glucose Sensor Based on Pt Nanoparticle/Polyaniline Hydrogel Heterostructures
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Self-citationRecent advances in polyaniline based biosensors
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Cited by
Liu, X., Liu, J., Lin, S., & Zhao, X. (2020) · Materials Today · doi:10.1016/j.mattod.2019.12.026 · Cited by 1,023
Stimuli‐Responsive Biomolecule‐Based Hydrogels and Their Applications
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Han, L., Yan, L., Wang, M., Wang, K., Fang, L., Zhou, J., Fang, J., Ren, F., & Lu, X. (2018) · Chemistry of Materials · doi:10.1021/acs.chemmater.8b01446 · Cited by 438
Hydrogel Based Sensors for Biomedical Applications: An Updated Review
Tavakoli, J., & Tang, Y. (2017) · Polymers · doi:10.3390/polym9080364 · Cited by 434
Ultrahigh‐Conductivity Polymer Hydrogels with Arbitrary Structures
Yao, B., Wang, H., Zhou, Q., Wu, M., Zhang, M., Li, C., & Shi, G. (2017) · Advanced Materials · doi:10.1002/adma.201700974 · Cited by 423
Metadata
- Authors
- Li, L., Wang, Y., Pan, L., Shi, Y., Cheng, W., Shi, Y., & Yu, G.
- Venue
- Nano Letters
- Publisher
- American Chemical Society (ACS)
- Published
- 2015-01-12
- Volume
- 15
- Issue
- 2
- Pages
- 1146-1151
- ISSN
- 1530-6984 (ISSN-L)
- 1530-6992
- OpenAlex
- W2133064818
- Cited by
- 422
- References
- 22
- FWCI
- 19.09
- Type
- journal article
- Language
- en
- Open access
- closed
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- Li, L., Wang, Y., Pan, L., Shi, Y., Cheng, W., Shi, Y., & Yu, G. (2015). A Nanostructured Conductive Hydrogels-Based Biosensor Platform for Human Metabolite Detection. Nano Letters. https://doi.org/10.1021/nl504217p
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