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Highly Sensitive Glucose Sensor Based on Pt Nanoparticle/Polyaniline Hydrogel Heterostructures

Zhai, Dongyuan, Liu, Borui, Shi, Yi, Pan, Lijia, Wang, Yaqun, Li, Wenbo, Zhang, Rong, Yu, Guihua·2013·ACS Nano

Abstract

Glucose enzyme biosensors have been shown useful for a range of applications from medical diagnosis, bioprocess monitoring, to beverage industry and environmental monitoring. We present here a highly sensitive glucose enzyme sensor based on Pt nanoparticles (PtNPs)-polyaniline (PAni) hydrogel heterostructures. High-density PtNPs were homogeneously loaded onto the three-dimensional (3D) nanostructured matrix of the PAni hydrogel. The PtNP/PAni hydrogel heterostructure-based glucose sensor synergizes the advantages of both the conducting hydrogel and the nanoparticle catalyst. The porous structure of the PAni hydrogel favored the high density immobilization of the enzyme and the penetration of water-soluble molecules, which helped efficiently catalyze the oxidation of glucose. In addition, the PtNPs catalyzed the decomposition of hydrogen peroxide that was generated during the enzymatic reaction. The transferred charges from these electrochemical processes were efficiently collected by the highly conducting PtNP/PAni hydrogel heterostructures. The glucose enzyme sensor based on this heterostructure exhibited unprecedented sensitivity, as high as 96.1 μA·mM(-1)·cm(-2), with a response time as fast as 3 s, a linear range of 0.01 to 8 mM, and a low detection limit of 0.7 μM.

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Metadata

Authors
Zhai, D., Liu, B., Shi, Y., Pan, L., Wang, Y., Li, W., Zhang, R., & Yu, G.
Venue
ACS Nano
Published
2013-03-14
Volume
7
Issue
4
Pages
3540-3546
ISSN
  • 1936-0851 (ISSN-L)
  • 1936-086X
OpenAlex
W2031449366
Cited by
814
References
4
FWCI
42.14
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Highly Sensitive Glucose Sensor Based on Pt Nanoparticle/Polyaniline Hydrogel Heterostructures. https://app.cochat.ai/papers/10.1021/nn400482d
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Zhai, D., Liu, B., Shi, Y., Pan, L., Wang, Y., Li, W., Zhang, R., & Yu, G. (2013). Highly Sensitive Glucose Sensor Based on Pt Nanoparticle/Polyaniline Hydrogel Heterostructures. ACS Nano. https://doi.org/10.1021/nn400482d

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