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Nanoparticulate Alternatives for Drug Delivery
Abstract
The ability to apply nanomaterials as targeted delivery agents for drugs and other therapeutics holds promise for a wide variety of diseases, including many types of cancer. A nanodelivery vehicle must demonstrate in vivo efficacy, diminished or no toxicity, stability, improved pharmacokinetics, and controlled-release kinetics. In this issue, Lee et al. construct polymer nanobins that fulfill these requirements and demonstrate effective delivery of doxorubicin in vivo to breast cancer cells. This Perspective explores the outlook for these nanobins as well as other technologies in this field and the challenges that lie ahead.
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Citations
Cited by
Bose, S., & Tarafder, S. (2012) · Acta Biomaterialia · doi:10.1016/j.actbio.2011.11.017 · Cited by 958
Gujrati, V., Kim, S., Kim, S.-H., Min, J. J., Choy, H. E., Kim, S. C., & Jon, S. (2014) · ACS Nano · doi:10.1021/nn405724x · Cited by 543
Yang, Q., Guo, N., Zhou, Y., Chen, J., Wei, Q., & Han, M. (2020) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2020.04.004 · Cited by 471
Mahmood, N., Mihalcioiu, C., & Rabbani, S. A. (2018) · Frontiers in Oncology · doi:10.3389/fonc.2018.00024 · Cited by 478
Delivery of chemotherapeutic drugs in tumour cell-derived microparticles
Tang, K., Zhang, Y., Zhang, H., Xu, P., Liu, J., Ma, J., Lv, M., Li, D., Katirai, F., Shen, G.-X., et al. (2012) · Nature Communications · doi:10.1038/ncomms2282 · Cited by 453
Recent advances in carrier mediated nose-to-brain delivery of pharmaceutics
Bourganis, V., Kammona, O., Alexopoulos, A., & Kiparissides, C. (2018) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2018.05.009 · Cited by 357
Haider, M. S., Lübtow, M. M., Endres, S., Forster, S., Flegler, V. J., Böttcher, B., Aseyev, V., Pöppler, A.-C., & Luxenhofer, R. (2020) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.9b22495 · Cited by 100
Functionalization of Nanomaterials: Synthesis and Characterization
Rizvi, M., Gerengi, H., & Gupta, P. (2022) · ACS Symposium Series · doi:10.1021/bk-2022-1418.ch001 · Cited by 55
Metadata
- Authors
- Adair, J. H., Parette, M. P., Altınoğlu, E. İ., & Kester, M.
- Venue
- ACS Nano
- Publisher
- American Chemical Society (ACS)
- Published
- 2010-09-28
- Volume
- 4
- Issue
- 9
- Pages
- 4967-4970
- ISSN
- 1936-0851 (ISSN-L)
- 1936-086X
- OpenAlex
- W2313365551
- Cited by
- 208
- References
- 0
- FWCI
- 6.35
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.