The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Multifunctional Fe3O4@Polydopamine Core–Shell Nanocomposites for Intracellular mRNA Detection and Imaging-Guided Photothermal Therapy
Open accessAbstract
Multifunctional nanocomposites have the potential to integrate sensing, diagnostic, and therapeutic functions into a single nanostructure. Herein, we synthesize Fe3O4@polydopamine core-shell nanocomposites (Fe3O4@PDA NCs) through an in situ self-polymerization method. Dopamine, a melanin-like mimic of mussel adhesive proteins, can self-polymerize to form surface-adherent polydopamine (PDA) films onto a wide range of materials including Fe3O4 nanoparticles used here. In such nanocomposites, PDA provides a number of advantages, such as near-infrared absorption, high fluorescence quenching efficiency, and a surface for further functionalization with biomolecules. We demonstrate the ability of the Fe3O4@PDA NCs to act as theranostic agents for intracellular mRNA detection and multimodal imaging-guided photothermal therapy. This work would stimulate interest in the use of PDA as a useful material to construct multifunctional nanocomposites for biomedical applications.
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Cites
Mussel-inspired surface chemistry for multifunctional coatings
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Photoacoustic tomography: In vivo imaging from organelles to organs
Wang, L. V., & Hu, S. (2012) · Science · doi:10.1126/science.1216210 · Cited by 4,331
Multifunctional Magnetic Nanoparticles: Design, Synthesis, and Biomedical Applications
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Self-citationFacile DNA immobilization on surfaces through a catecholamine polymer
Ham, H. O., Liu, Z., Lau, K. H. A., Lee, H., & Messersmith, P. B. (2011) · Angewandte Chemie International Edition · doi:10.1002/anie.201005001 · Cited by 189
Cited by
Polydopamine Surface Chemistry: A Decade of Discovery
Ryu, J. H., Messersmith, P. B., & Lee, H. (2018) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.7b19865 · Cited by 1,843
Iron oxide nanoparticles: Diagnostic, therapeutic and theranostic applications
Dadfar, S. M., Roemhild, K., Drude, N. I., von Stillfried, S., Knüchel, R., Kiessling, F., & Lammers, T. (2019) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2019.01.005 · Cited by 1,181
Bao, X., Zhao, J., Sun, J., Hu, M., & Yang, X. (2018) · ACS Nano · doi:10.1021/acsnano.8b04022 · Cited by 722
Polyphenol‐Containing Nanoparticles: Synthesis, Properties, and Therapeutic Delivery
Guo, Y., Sun, Q., Wu, F., Dai, Y., & Chen, X. (2021) · Advanced Materials · doi:10.1002/adma.202007356 · Cited by 650
Self-citationLiu, M., Zeng, G., Wang, K., Wan, Q., Tao, L., Zhang, X., & Wei, Y. (2016) · Nanoscale · doi:10.1039/c5nr09078d · Cited by 561
Metadata
- Authors
- Lin, L.-S., Cong, Z.-X., Cao, J.-B., Ke, K.-M., Peng, Q.-L., Gao, J., Yang, H.-H., Liu, G., & Chen, X.
- Venue
- ACS Nano
- Publisher
- American Chemical Society (ACS)
- Published
- 2014-03-26
- Volume
- 8
- Issue
- 4
- Pages
- 3876-3883
- ISSN
- 1936-0851 (ISSN-L)
- 1936-086X
- OpenAlex
- W2330246146
- Cited by
- 653
- References
- 4
- FWCI
- 33.60
- Type
- journal article
- Language
- en
- Open access
- green
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- Lin, L.-S., Cong, Z.-X., Cao, J.-B., Ke, K.-M., Peng, Q.-L., Gao, J., Yang, H.-H., Liu, G., & Chen, X. (2014). Multifunctional Fe3O4@Polydopamine Core–Shell Nanocomposites for Intracellular mRNA Detection and Imaging-Guided Photothermal Therapy. ACS Nano. https://doi.org/10.1021/nn500722y
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