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Cited by 650

The DOI matches its Crossref record; 257 of the 257 references it cites were found in a registry or an index.

Polyphenol‐Containing Nanoparticles: Synthesis, Properties, and Therapeutic Delivery

Guo, Yuxin, Sun, Qing, Wu, Fu‐Gen, Dai, Yunlu, Chen, Xiaoyuan·2021·Advanced Materials

Abstract

Polyphenols, the phenolic hydroxyl group‐containing organic molecules, are widely found in natural plants and have shown beneficial effects on human health. Recently, polyphenol‐containing nanoparticles have attracted extensive research attention due to their antioxidation property, anticancer activity, and universal adherent affinity, and thus have shown great promise in the preparation, stabilization, and modification of multifunctional nanoassemblies for bioimaging, therapeutic delivery, and other biomedical applications. Additionally, the metal−polyphenol networks, formed by the coordination interactions between polyphenols and metal ions, have been used to prepare an important class of polyphenol‐containing nanoparticles for surface modification, bioimaging, drug delivery, and disease treatments. By focusing on the interactions between polyphenols and different materials (e.g., metal ions, inorganic materials, polymers, proteins, and nucleic acids), a comprehensive review on the synthesis and properties of the polyphenol‐containing nanoparticles is provided. Moreover, the remarkable versatility of polyphenol‐containing nanoparticles in different biomedical applications, including biodetection, multimodal bioimaging, protein and gene delivery, bone repair, antibiosis, and cancer theranostics is also demonstrated. Finally, the challenges faced by future research regarding the polyphenol‐containing nanoparticles are discussed.

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Metadata

Authors
Guo, Y., Sun, Q., Wu, F., Dai, Y., & Chen, X.
Venue
Advanced Materials
Publisher
Wiley
Published
2021-04-19
Volume
33
Issue
22
Pages
e2007356-e2007356
ISSN
  • 0935-9648 (ISSN-L)
  • 1521-4095
OpenAlex
W3153073177
Cited by
650
References
257
FWCI
19.30
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Polyphenol‐Containing Nanoparticles: Synthesis, Properties, and Therapeutic Delivery. https://app.cochat.ai/papers/10.1002/adma.202007356
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Guo, Y., Sun, Q., Wu, F., Dai, Y., & Chen, X. (2021). Polyphenol‐Containing Nanoparticles: Synthesis, Properties, and Therapeutic Delivery. Advanced Materials. https://doi.org/10.1002/adma.202007356

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