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A Microfabricated Nanoreactor for Safe, Continuous Generation and Use of Singlet Oxygen
Abstract
Singlet oxygen was effectively and safely generated in a nanoscale reactor and used for the synthesis of ascaridole. The technique allows for the generation of singlet oxygen without the inherent dangers of large quantities of oxygenated solvents. The methodology allows for facile scale-out of the process.
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Citations
Cited by
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Hoffmann, N. (2008) · Chemical Reviews · doi:10.1021/cr0680336 · Cited by 1,445
Greener Approaches to Organic Synthesis Using Microreactor Technology
Mason, B. P., Price, K. E., Steinbacher, J. L., Bogdan, A. R., & McQuade, D. T. (2007) · Chemical Reviews · doi:10.1021/cr050944c · Cited by 985
Using Singlet Oxygen to Synthesize Natural Products and Drugs
Ghogare, A. A., & Greer, A. (2016) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00726 · Cited by 719
Flow Chemistry – A Key Enabling Technology for (Multistep) Organic Synthesis
Wegner, J., Ceylan, S., & Kirschning, A. (2012) · Advanced Synthesis & Catalysis · doi:10.1002/adsc.201100584 · Cited by 639
Microchemical systems for continuous-flow synthesis
Hartman, R. L., & Jensen, K. F. (2009) · Lab on a Chip · doi:10.1039/b906343a · Cited by 508
A review of intensification of photocatalytic processes
Van Gerven, T., Mul, G., Moulijn, J., & Stankiewicz, A. (2007) · Chemical Engineering and Processing: Process Intensification · doi:10.1016/j.cep.2007.05.012 · Cited by 465
Flow photochemistry: Old light through new windows
Knowles, J. P., Elliott, L. D., & Booker-Milburn, K. I. (2012) · Beilstein Journal of Organic Chemistry · doi:10.3762/bjoc.8.229 · Cited by 398
The application of micro reactors for organic synthesis
Watts, P., & Haswell, S. J. (2005) · Chemical Society Reviews · doi:10.1039/b313866f · Cited by 384
The Use of Gases in Flow Synthesis
Mallia, C. J., & Baxendale, I. R. (2016) · Organic Process Research & Development · doi:10.1021/acs.oprd.5b00222 · Cited by 361
Advanced organic synthesis using microreactor technology
Ahmed-Omer, B., Brandt, J. C., & Wirth, T. (2007) · Org. Biomol. Chem. · doi:10.1039/b615072a · Cited by 320
Metadata
- Authors
- Wootton, R. C. R., Fortt, R., & de Mello, A. J.
- Venue
- Organic Process Research & Development
- Publisher
- American Chemical Society (ACS)
- Published
- 2002-01-23
- Volume
- 6
- Issue
- 2
- Pages
- 187-189
- ISSN
- 1083-6160 (ISSN-L)
- 1520-586X
- OpenAlex
- W1968451994
- Cited by
- 167
- References
- 0
- FWCI
- 6.04
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
