Marine pharmacology

Isolation and structure of bryostatin 1

Pettit, G. R., Herald, C. L., Doubek, D. L., Herald, D. L., Arnold, E., & Clardy, J. (1982) · Journal of the American Chemical Society · doi:10.1021/ja00388a092 · Cited by 653

The isolation and structure of a remarkable marine animal antineoplastic constituent: dolastatin 10

Pettit, G. R., Kamano, Y., Herald, C. L., Tuinman, A. A., Boettner, F. E., Kizu, H., Schmidt, J. M., Baczynskyj, L., Tomer, K. B., & Bontems, R. J. (1987) · Journal of the American Chemical Society · doi:10.1021/ja00256a070 · Cited by 583

Halichondrins-antitumor polyether macrolides from a marine sponge

Hirata, Y., & Uemura, D. (1986) · Pure and Applied Chemistry · doi:10.1351/pac198658050701 · Cited by 519

Ecteinascidins 729, 743, 745, 759A, 759B, and 770: potent antitumor agents from the Caribbean tunicate Ecteinascidia turbinata

RINEHART, K. L. J., Holt, T. G., Fregeau, N. L., Stroh, J. G., Keifer, P. A., Sun, F.-R., Li, L. H., & Martin, D. G. (1990) · The Journal of Organic Chemistry · doi:10.1021/jo00302a007 · Cited by 493

The structure of scytonemin, an ultraviolet sunscreen pigment from the sheaths of cyanobacteria

Proteau, P. J., Gerwick, W. H., Garcia-Pichel, F., & Castenholz, R. (1993) · Experientia · doi:10.1007/bf01923559 · Cited by 392

Discodermolide, A Cytotoxic Marine Agent That Stabilizes Microtubules More Potently Than Taxol,

ter Haar, E., Kowalski, R. J., Hamel, E., Lin, C. M., Longley, R. E., Gunasekera, S. P., Rosenkranz, H. S., & Day, B. W. (1996) · Biochemistry · doi:10.1021/bi9515127 · Cited by 382

Discodermolide: a new bioactive polyhydroxylated lactone from the marine sponge Discodermia dissoluta

Gunasekera, S. P., Gunasekera, M., Longley, R. E., & Schulte, G. K. (1990) · The Journal of Organic Chemistry · doi:10.1021/jo00303a029 · Cited by 377

Structure of curacin A, a novel antimitotic, antiproliferative and brine shrimp toxic natural product from the marine cyanobacterium Lyngbya majuscula

Gerwick, W. H., Proteau, P. J., Nagle, D. G., Hamel, E., Blokhin, A., & Slate, D. L. (1994) · The Journal of Organic Chemistry · doi:10.1021/jo00085a006 · Cited by 365

Jasplakinolide, a cyclodepsipeptide from the marine sponge, SP.

Crews, P., Manes, L. V., & Boehler, M. A. (1986) · Tetrahedron Letters · doi:10.1016/s0040-4039(00)84645-6 · Cited by 319

Didemnins: Antiviral and Antitumor Depsipeptides from a Caribbean Tunicate

Rinehart, K. L., Gloer, J. B., Hughes, R. G., Renis, H. E., McGovren, J. P., Swynenberg, E. B., Stringfellow, D. A., Kuentzel, S. L., & Li, L. H. (1981) · Science · doi:10.1126/science.7233187 · Cited by 314

Potensi Antitumor Ekstrak Spons Crella papilata Asal Taman Nasional Laut Kepulauan Seribu

Fajarningsih, N. D., Januar, H. I., Nursid, M., & Wikanta, T. (2006) · Jurnal Pascapanen dan Bioteknologi Kelautan dan Perikanan · doi:10.15578/jpbkp.v1i1.229 · Cited by 16

Gastroprotective and toxicological evaluation of the Lithothamnion calcareum algae

Almeida, F., Schiavo, L. V., Vieira, A. D., Araújo, G. L., Queiroz‐Junior, C. M., Teixeira, M. M., Cassali, G. D., & Tagliati, C. A. (2012) · Food and Chemical Toxicology · doi:10.1016/j.fct.2012.02.028 · Cited by 15

Maritime trade and migratory species management to protect biodiversity

Fernandez, L. M. (2007) · Environmental and Resource Economics · doi:10.1007/s10640-006-9069-0 · Cited by 15

Antimicrobial Activity of Sulfated Mucopolysaccharides [Heparin and Heparin-Like Glycosaminoglycans (GAGs)] from Cuttlefish Euprymna berryi Sasaki, 1929

Shanmugam, A., Amalraj, T., Palpandi, C., & Balasubramanian, T. (2008) · Trends in Applied Sciences Research · doi:10.3923/tasr.2008.97.102 · Cited by 14

Aquaculture of “Non-Food Organisms” for Natural Substance Production

Liebezeit, G. (2005) · Advances in biochemical engineering, biotechnology · doi:10.1007/b135821 · Cited by 14

Marine Biotechnology

Lindequist, U., & Schweder, T. (2001) · Wiley eBooks · doi:10.1002/9783527620999.ch15k · Cited by 14

Antimicrobial activity of methanolic extract and fractionated polysaccharide from Loligo duvauceli Orbingy 1848 and Doryteuthis sibogae Adam 1954 on human pathogenic microorganisms

Vino, A. B., Vairamani, S., & Shanmugam, A. (2014) · African Journal of Microbiology Research · doi:10.5897/ajmr12.227 · Cited by 13

Anti-Nociceptive Assets of Coral Associated Gastropod, Drupa margariticola

Chellaram, C., & Edward, J. K. P. (2009) · International Journal of Pharmacology · doi:10.3923/ijp.2009.236.239 · Cited by 13

Marine Natural Products: Biodiscovery, Biodiversity, and Bioproduction

Leal, M. C., & Calado, R. (2014) · Wiley eBooks · doi:10.1002/9783527684403.ch17 · Cited by 12

Novel and highly potent antitumour natural products from cnidarians of marine origin

Pejin, B., Mojović, M., & Savic, A. G. (2014) · Natural Product Research · doi:10.1080/14786419.2014.934241 · Cited by 12

Evaluation of the Biological Activities of Marine Bacteria Collected from Jeju Island, Korea, and Isolation of Active Compounds from their Secondary Metabolites

Kim, H.-S., Zhang, C., Lee, J., Ko, J.-Y., Kim, E.-A., Kang, N., & Jeon, Y. (2014) · Fisheries and aquatic sciences · doi:10.5657/fas.2014.0215 · Cited by 12

Total synthesis, biological evaluation of dendrodolides A–D and their analogues

Poornima, B., Venkanna, A., Swetha, B. V., Reddy, K. R. K., Siva, B., Babu, V. S., Ummanni, R., & Babu, K. S. (2016) · Tetrahedron · doi:10.1016/j.tet.2016.06.042 · Cited by 12

Molecular design of anticancer drugs from marine fungi derivatives

Cao, D. T., Doan, T. M. H., Pham, V. C., Le, T. H. M., Chae, J., Yun, H., Na, M., Kim, Y. H., Quân, P. M., & Nguyen, V. H. (2021) · RSC Advances · doi:10.1039/d1ra01855h · Cited by 12

Aquaculture of the Big-Bellied Seahorse Hippocampus Abdominalis Lesson 1827 (Teleostei: Syngnathidae)

Woods, C. M. C. (2007) · Open Access Victoria University of Wellington | Te Herenga Waka (Figshare) · doi:10.26686/wgtn.16926514 · Cited by 12

Sponges of the Red Sea

Wooster, M. K., Voigt, O., Erpenbeck, D., Wörheide, G., & Berumen, M. L. (2019) · Coral reefs of the world · doi:10.1007/978-3-030-05802-9_6 · Cited by 11

Antimicrobial Activities of Two Edible Bivalves M. meretrix and M. casta

Sugesh, S., & Mayavu, P. (2012) · Pakistan Journal of Biological Sciences · doi:10.3923/pjbs.2013.38.43 · Cited by 11

Potential inhibitors for SARS-CoV-2 Mpro from marine compounds

Tâm, N. M., Quân, P. M., Nguyen, H. T., Hong, N. D., Hien, N. K., Quang, D. T., Phùng, H. T. T., & Ngô, S. T. (2021) · RSC Advances · doi:10.1039/d1ra03852d · Cited by 11

A Phenotypic Screening Approach to Identify Anticancer Compounds Derived from Marine Fungi

Ellinger, B., Silber, J., Prashar, A., Landskron, J., Weber, J., Rehermann, S., Müller, F.-J., Smith, S., Wrigley, S. K., Taskén, K., et al. (2014) · Assay and Drug Development Technologies · doi:10.1089/adt.2013.564 · Cited by 10

Marine organisms from Brazil as source of potential anticancer agents

Costa-Lotufo, L. V., Pessoa, C., de Moraes, M. E. A., Almeida, A. M. P., de Moraes, M. O., & Lotufo, T. M. D. C. (2006) · Advances in phytomedicine · doi:10.1016/s1572-557x(05)02011-8 · Cited by 10

Alcyonacea: A Potential Source for Production of Nitrogen-Containing Metabolites

Alarif, W. M., Abdel‐Lateff, A., Alorfi, H. S., & Alburae, N. A. (2019) · Molecules · doi:10.3390/molecules24020286 · Cited by 10

Isolation, purification and structural elucidation of secondary metabolites from Microcystis aeruginosa bloom from Muttukadu estuary and its in vitro antibacterial, antioxidant and anticancer potency

Vasudevan, S., Arulmoorthy, M. P., & Suresh, R. (2020) · South African Journal of Botany · doi:10.1016/j.sajb.2020.03.030 · Cited by 10

Standardized Extract of the Persian Gulf Sponge, Axinella Sinoxea Selectively Induces Apoptosis through Mitochondria in Human Chronic Lymphocytic Leukemia Cells

Salimi, A., Saharkhiz, M. P., Motallebi, A., Seydi, E., Mohseni, A., Nazemi, M., & Pourahmad, J. (2015) · Journal of Analytical Oncology · doi:10.6000/1927-7229.2015.04.04.2 · Cited by 9

An In vitro Approach for Evaluating Antimicrobial Activity and Production of Kojic Acid by Aspergillus flavus Isolated from Karwar Region

Sanjotha, G., Shivasharana, C. T., & Manawadi, S. I. (2019) · Journal of Pure and Applied Microbiology · doi:10.22207/jpam.13.4.40 · Cited by 9

Conservation of dark habitats

Navarro‐Barranco, C., Ambroso, S., Gerovasileiou, V., Gómez‐Gras, D., Grinyó, J., Montseny, M., & Santín, A. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-85613-3.00005-0 · Cited by 9

Evaluation of hexane and ethyl acetate extracts of the sponge Jaspis diastra collected from Mauritius Waters on HeLa cells

Beedessee, G., Ramanjooloo, A., Tiscornia, I. S., Cresteil, T., Raghothama, S., Arya, D., Rao, S., Gowd, K. H., Bollati‐Fogolín, M., & Marie, D. E. P. (2014) · Journal of Pharmacy and Pharmacology · doi:10.1111/jphp.12256 · Cited by 9

Metabolitos secundarios, letalidad y actividad antimicrobiana de los extractos de tres corales y tres moluscos marinos de Sucre, Venezuela

Ordaz, G., D'Armas, H. T., Yáñez, D., Hernández, J., & Camacho, A. (2009) · Revista de Biología Tropical · doi:10.15517/rbt.v58i2.5238 · Cited by 7

Phylogenetic diversity of Type I polyketide synthase genes from sediments of Ardley Island in Antarctica

Zhao, J., Yang, N., Chen, X., Jiang, Q., & Zeng, R. (2011) · Acta Oceanologica Sinica · doi:10.1007/s13131-011-0167-7 · Cited by 7

Marine derivatives preventwMUS81in silicostudies

Ngô, S. T., Vu, K. B., Quân, P. M., Tâm, N. M., & Tran, P. (2021) · Royal Society Open Science · doi:10.1098/rsos.210974 · Cited by 7

Antibacterial Activity of Methanolic Extract of Whole Body Tissue and Ethylene Diamine Tetra Acetate Extract of Cuttlebone of Sepiella inermis (Orbigny, 1848)

Vairamani, S., Subhapradh, N., Ramasamy, P., Vino, A. B., Raveendran, S. S., & Shanmugam, A. (2012) · Research Journal of Microbiology · doi:10.3923/jm.2012.263.272 · Cited by 7

Nanocatalytic Efficacy of Silver Nanoparticles Fabricated using Chaetomorpha antennina Algal Extract, Their Characterization, and Its Applications

Kingslin, A., Kalimuthu, K., & Viswanathan, P. (2022) · Journal of Scientific Research · doi:10.3329/jsr.v14i1.53782 · Cited by 7

Managing Hull-Borne Invasive Species and Coastal Water Quality for California and Baja California Boats Kept in Saltwater

Johnson, L., Gonzalez, J. A., Alvarez, C., Takada, M., Himes‐Cornell, A., Showalter, S., & Savarese, J. (2007) · doi:10.3733/ucanr.8359 · Cited by 7

Cytotoxic Cyclic Peptides from the Marine Sponges

Wakimoto, T., Tan, K. C., Tajima, H., & Abe, I. (2014) · Springer eBooks · doi:10.1007/978-3-319-07145-9_6 · Cited by 6

Potent bioactive compounds from the ocean: some interesting aspects and applications

Pandey, K. (2012) · Pharmacognosy Journal · doi:10.5530/pj.2012.27.1 · Cited by 6

Indole-Producing Bacteria from the Biosynthetic Organs of a Muricid Mollusc Could Contribute to Tyrian Purple Production

Ngangbam, A. K., Waters, D. L., Whalan, S., Baten, A., & Benkendorff, K. (2015) · Journal of Shellfish Research · doi:10.2983/035.034.0228 · Cited by 6

Calculation of binding affinity of JAK1 inhibitors via accurately computational estimation

Le, T.-T.-H., Tran, L. H., Nguyen, M. T., Pham, M. Q., & Phùng, H. T. T. (2022) · Journal of Biomolecular Structure and Dynamics · doi:10.1080/07391102.2022.2118830 · Cited by 6

Evaluation of Methods for Storage of Marine Macroorganisms with Optimal Recovery of Bacteria

Siebert, K., Busl, M., Asmus, I., Freund, J., Muscholl‐Silberhorn, A., & Wirth, R. (2004) · Applied and Environmental Microbiology · doi:10.1128/aem.70.10.5912-5915.2004 · Cited by 6

Sponges: A Reservoir for Microorganism‐Derived Bioactive Metabolites

Amarendra, V., Santhosh, R. S., & Dhevendaran, K. (2013) · Wiley eBooks · doi:10.1002/9783527665259.ch24 · Cited by 5

Natural Products with Anticancer Activity from Marine Fungi

Karuppiah, V., Zhang, F., & Li, Z. (2014) · Springer eBooks · doi:10.1007/978-3-319-07145-9_13 · Cited by 5

Hemolytic Activities from Ascidian Polyclinum madrasensis Sebestian, 1952 and Phallusia nigra Savigny, 1816 from Tuticorin Coast of India

Bragadeesw, S., Ganesan, K., & kumara, N. (2011) · Asian Journal of Applied Sciences · doi:10.3923/ajaps.2011.630.639 · Cited by 5

Antibacterial and cytotoxicity activities of bioactive compounds from Micrococcus species OUS9 isolated from sea water

Kumari, K. S., Shivakrishna, P., Al-Attar, A. M., & Ganduri, V. S. R. K. (2020) · Journal of King Saud University - Science · doi:10.1016/j.jksus.2020.07.003 · Cited by 5

Antitumor potential of natural products from marine ascidians of the Gibraltar Strait: A survey

Zubı́a, E., Ortega, M. J., & Salvá, J. (2003) · Ciencias Marinas · doi:10.7773/cm.v29i2.141 · Cited by 5

Industry Potential of Marine Bioactive Components: Downstream Processing and Vehicles for Efficient Delivery In Situ

Brück, W. M., Reiße, S., Garbe, D., & Brück, T. (2011) · Springer eBooks · doi:10.1007/978-1-4614-1247-2_5 · Cited by 4

Development of (4-Phenylamino)quinazoline Alkylthiourea Derivatives as Novel NF-κB Inhibitors

Darwish, S. S., Chen, P., Hamed, M. M., Wagdy, R. A., Chen, S.-H., Abadi, A., Abdel‐Halim, M., Hwang, T., & Engel, M. (2022) · Pharmaceuticals · doi:10.3390/ph15070778 · Cited by 4

Inhibitory effects of bioactive leads isolated from Pseudomonas aeruginosa PS3 and Pseudomonas fluorescens PS7 on MAP kinases and down regulation of pro inflammatory cytokines (TNF-α, IL-1β) and mediators (NO, iNOS and COX)

Rupesh, K. R., Priya, A. M., Prashanth, K., & Jayachandran, S. (2012) · Toxicology in Vitro · doi:10.1016/j.tiv.2012.01.023 · Cited by 4

Marine Bioprospecting: Bioactive Compounds from Cnidarians and Molluscs - A ReviewPreprint

Pathak, S. (2020) · SSRN Electronic Journal · doi:10.2139/ssrn.3567752 · Cited by 4

Screening of anti-Candida albicans metabolites produced by marine sponge-associated bacteria

Kusumawati, P., Murti, Y. B., & Wijayanti, N. (2020) · Marine Research in Indonesia · doi:10.14203/mri.v45i2.575 · Cited by 3

Evaluation of Antibacterial Activity and Characterization of Phytochemical Compounds from Selected Mangrove Plants

Duraipandian, M., Abirami, H., Musthafa, K., & Karuthapandian, S. (2022) · International Journal of Biomedicine · doi:10.21103/article12(4)_oa22 · Cited by 3

Marine Sponge Sigmadocia pumila a potential supply for drug findings

Bhimba, B. V., Vinod, V., & Beulah, C. (2013) · Journal of Pharmacy Research · doi:10.1016/j.jopr.2013.04.006 · Cited by 3

Anticancer Compounds from Marine Microorganisms

Shin, H. Y. (2012) · CRC Press eBooks · doi:10.1201/b13868-35 · Cited by 3

Corals

Khalesi, M. K. (2015) · Springer eBooks · doi:10.1007/978-3-642-53971-8_7 · Cited by 3

Natural Products in the 21st Century

Singh, S. B. (2011) · Springer eBooks · doi:10.1007/978-1-4614-1400-1_25 · Cited by 2

Marine Sponge Derived Actinomycetes and Their Anticancer Compounds

Sivakumar, K., Manivasagan, P., & Kim, S. (2014) · Springer eBooks · doi:10.1007/978-3-319-07145-9_34 · Cited by 2

Therapeutic Drugs

Kumar, N. S. S., Kumar, N. S. V., & Jaiganesh, R. (2012) · Advances in food and nutrition research · doi:10.1016/b978-0-12-416003-3.00018-4 · Cited by 2

Screening for antibacterial molecules in meiobenthic nematodes belonging to the Oncholaimidae family

Bruno, R., Zeppilli, D., Boidin‐Wichlacz, C., Sandulli, R., & Tasiemski, A. (2021) · HAL · doi:10.21411/cbm.a.d87636d · Cited by 2

Bacterial Symbionts of Soft Coral Lobophytum Sp. From Panjang Island, Jepara, Indonesia With Antimicrobial MDR TB Potency

Franyoto, Y. D., Masduqi, A. F., Muchlissin, S. I., Widyananto, P. A., Sulistyani, Wijayanti, D. P., & Kusmita, L. (2019) · Journal Of Tropical Pharmacy And Chemistry · doi:10.30872/j.trop.pharm.chem.v4i5.272 · Cited by 1

Searching potential GSK-3β inhibitors from marine sources using atomistic simulations

Van, T. T. H., Pham, M. Q., Huong, T. T. T., Long, B. N. T., Long, P. Q., Huong, L. T. T., Lenon, G. B., Uyen, N. T. T., & Ngo, S. T. (2025) · Molecular Diversity · doi:10.1007/s11030-025-11174-x · Cited by 1

ISOLATION AND ENZYMATIC FRAGMENTATION OF GENOMIC DNA FROM UNCULTURED MICROBIAL SYMBIONTS OF Theonella sp. SPONGE AS PREREQUISITE FOR METAGENOMIC LIBRARY CONSTRUCTION

Uria, A. R., Munifah, L., & Chasanah, E. (2017) · Indonesian Fisheries Research Journal · doi:10.15578/ifrj.13.2.2007.125-130 · Cited by 1

Isolation and structure elucidation of acetyl cholinesterase inhibitor from Gyrostoma helianthus of the Red Sea, Egypt

M, N. G., A, M. F., Ayesh, A. M., & M, A. E. (2015) · Journal of Cell and Animal Biology · doi:10.5897/jcab2015.0431 · Cited by 1

Marine Biotechnology

Lindequist, U., & Schweder, T. (2001) · Biotechnology · doi:10.1002/9783527620937.ch15 · Cited by 1

Colorectal Cancer

Khaliq, R., Iqbal, P., & Wani, A. Y. (2022) · Advances in medical diagnosis, treatment, and care (AMDTC) book series · doi:10.4018/978-1-7998-9258-8.ch006 · Cited by 1

Basic Marine Pharmacology

Kornprobst, J. (2014) · Wiley eBooks · doi:10.1002/9783527335855.marprod004 · Cited by 1

Denizel biyoaktif bileşikler.

Özkaya, F. C., Erdoğan, C., & Altunok, M. (2013) · Ege Journal of Fisheries and Aquatic Sciences · doi:10.12714/egejfas.2013.30.2.08

Isolation of Actinobacteria from Sponges

Kamarudheen, N., & Rao, K. V. B. (2022) · Springer protocols handbooks/Springer protocols · doi:10.1007/978-1-0716-1728-1_5

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Therapeutically Active Marine Sponge Isolated from Rameshwaram Thoppu Kaadu Theevu against MDR Pathogen Lactobacillus acidophilus Isolated from Childhood Caries

Vijayalakshmi, S., & Mohankumar, A. (2022) · International Journal of Biochemistry and Biophysics · doi:10.13189/ijbb.2022.100301

Marine World of Terpenes Targeting Specific Cancers

Vinchurkar, K., Mane, S., Gupta, D., Sakalle, N. S., & Neha, K. (2025) · IGI Global eBooks · doi:10.4018/979-8-3693-6972-2.ch010

Identification, characterization and functions of antimicrobial peptides in extremophile worms

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Trends in Development of Marine‐based Anti‐inflammatory Pharmaceuticals

Malaweera, D. B. O., & Wijesundara, N. M. (2020) · Encyclopedia of Marine Biotechnology · doi:10.1002/9781119143802.ch112 · Cited by 1

Marine anticancer drugs and their relevant targets: a treasure from the ocean

Nigam, M., Suleria, H. A. R., Farzaei, M. H., & Mishra, A. P. (2019) · DARU Journal of Pharmaceutical Sciences · doi:10.1007/s40199-019-00273-4 · Cited by 53

Marine natural products as a source of novel pharmacological agents

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Marine Drugs: A Hidden Wealth and a New Epoch for Cancer Management

Shakeel, E., Arora, D., Jamal, Q. M. S., Akhtar, S., Khan, M. K. A., Kamal, M. A., Siddiqui, M. H., Lohani, M., & Arif, J. M. (2017) · Current Drug Metabolism · doi:10.2174/1389200218666170221105402 · Cited by 9

Marine Microorganism Molecules as Potential Anti-Inflammatory Therapeutics

Lasalo, M., Jauffrais, T., Georgel, P., & Matsui, M. (2024) · Marine Drugs · doi:10.3390/md22090405 · Cited by 10