The Neurobiology of Dopamine Signaling

Synaptic Vesicle Phosphoproteins and Regulation of Synaptic Function

Greengard, P., Valtorta, F., Czernik, A. J., & Benfenati, F. (1993) · Science · doi:10.1126/science.8430330 · Cited by 1,311 · see citing works

Beyond the Dopamine Receptor

Greengard, P., Allen, P. B., & Nairn, A. C. (1999) · Neuron · doi:10.1016/s0896-6273(00)80798-9 · Cited by 748 · see citing works

DARPP-32, a dopamine-regulated neuronal phosphoprotein, is a potent inhibitor of protein phosphatase-1

Hemmings, H. C., Greengard, P., Tung, H. Y. L., & Cohen, P. (1984) · Nature · doi:10.1038/310503a0 · Cited by 613 · see citing works

Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons

Bibb, J. A., Snyder, G. L., Nishi, A., Yan, Z., Meijer, L., Fienberg, A. A., Tsai, L., Kwon, Y. T., Girault, J., Czernik, A. J., et al. (1999) · Nature · doi:10.1038/45251 · Cited by 553 · see citing works

Enhancement of the Glutamate Response by cAMP-Dependent Protein Kinase in Hippocampal Neurons

Greengard, P., Jen, J. C., Nairn, A. C., & Stevens, C. F. (1991) · Science · doi:10.1126/science.1716001 · Cited by 498 · see citing works

DARPP-32: Regulator of the Efficacy of Dopaminergic Neurotransmission

Fienberg, A. A., Hiroi, N., Mermelstein, P. G., Song, W., Snyder, G. L., Nishi, A., Chéramy, A., O'Callaghan, J. P., Miller, D. B., Cole, D. G., et al. (1998) · Science · doi:10.1126/science.281.5378.838 · Cited by 491 · see citing works

Spinophilin, a novel protein phosphatase 1 binding protein localized to dendritic spines

Allen, P. B., Ouimet, C. C., & Greengard, P. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.18.9956 · Cited by 454 · see citing works

Dopamine-Sensitive Adenyl Cyclase: Possible Role in Synaptic Transmission

Kebabian, J. W., & Greengard, P. (1971) · Science · doi:10.1126/science.174.4016.1346 · Cited by 422 · see citing works

Regulation of Kainate Receptors by cAMP-Dependent Protein Kinase and Phosphatases

Wang, L., Salter, M. W., & MacDonald, J. F. (1991) · Science · doi:10.1126/science.1653455 · Cited by 395 · see citing works

Intracellular injection of t he catalytic subunit of cyclic AMP-dependent protein kinase simulates facilitation of transmitter release underlying behavioral sensitization in Aplysia.

Castellucci, V. F., Kandel, E. R., Schwartz, J. H., Wilson, F. D., Nairn, A. C., & Greengard, P. (1980) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.77.12.7492 · Cited by 383 · see citing works

Anchoring of protein kinase A is required for modulation of AMPA/kainate receptors on hippocampal neurons

Rosenmund, C., Carr, D. W., Bergeson, S. E., Nilaver, G., Scott, J. D., & Westbrook, G. L. (1994) · Nature · doi:10.1038/368853a0 · Cited by 371 · see citing works

A dopamine- and cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions

Walaas, S. I., Aswad, D. W., & Greengard, P. (1983) · Nature · doi:10.1038/301069a0 · Cited by 345 · see citing works

Stimulation of brain membrane protein phosphorylation by calcium and an endogenous heat-stable protein

Schulman, H., & Greengard, P. (1978) · Nature · doi:10.1038/271478a0 · Cited by 336 · see citing works

Cyclic Nucleotide-dependent Protein Kinases

Kuo, J. F., & Greengard, P. (1970) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)63097-2 · Cited by 335 · see citing works

Protein phosphatase 1 modulation of neostriatal AMPA channels: regulation by DARPP–32 and spinophilin

Yan, Z., Hsieh-Wilson, L., Feng, J., Tomizawa, K., Allen, P., Fienberg, A., Nairn, A., & Greengard, P. (1999) · Nature Neuroscience · doi:10.1038/4516 · Cited by 304 · see citing works

Regional distribution of calcium- and cyclic adenosine 3':5'- monophosphate-regulated protein phosphorylation systems in mammalian brain. II. Soluble systems

Walaas, S. I., Nairn, A. C., & Greengard, P. (1983) · Journal of Neuroscience · doi:10.1523/jneurosci.03-02-00302.1983 · Cited by 235 · see citing works

Inhibitor of adenosine 3':5'-monophosphate-dependent protein kinase blocks presynaptic facilitation in Aplysia

Castellucci, V. F., Nairn, A. C., Greengard, P., Schwartz, J. H., & Kandel, E. R. (1982) · Journal of Neuroscience · doi:10.1523/jneurosci.02-12-01673.1982 · Cited by 204 · see citing works

Phosphorylation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, by casein kinase II

Girault, J., Hemmings, H. C., Williams, K. R., Nairn, A. C., & Greengard, P. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(20)88248-9 · Cited by 172 · see citing works

Differential expression of protein phosphatase 1 isoforms in mammalian brain

Silva, E. D. C. E., Fox, C., Ouimet, C. C., Gustafson, E. L., Watson, S. J., & Greengard, P. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-05-03375.1995 · Cited by 163 · see citing works

Adenosine 3′,5′-Monophosphate-Dependent Protein Kinase from Brain

Miyamoto, E., Kuo, J. F., & Greengard, P. (1969) · Science · doi:10.1126/science.165.3888.63 · Cited by 148 · see citing works

Phosphorylation of DARPP-32, a Dopamine- and cAMP-regulated Phosphoprotein, by Casein Kinase I in Vitro and in Vivo

Desdouits, F., Cohen, D., Nairn, A. C., Greengard, P., & Girault, J. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.15.8772 · Cited by 78 · see citing works

Behavioral functions of the mesolimbic dopaminergic system: An affective neuroethological perspective

Alcaro, A., Huber, R., & Panksepp, J. (2007) · Brain Research Reviews · doi:10.1016/j.brainresrev.2007.07.014 · Cited by 614 · see citing works

The Dual-State Theory of Prefrontal Cortex Dopamine Function with Relevance to Catechol-O-Methyltransferase Genotypes and Schizophrenia

Durstewitz, D., & Seamans, J. K. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.05.015 · Cited by 586 · see citing works

Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings

Dichter, G. S., Damiano, C. A., & Allen, J. A. (2012) · Journal of Neurodevelopmental Disorders · doi:10.1186/1866-1955-4-19 · Cited by 299 · see citing works

How NaCl raises blood pressure: a new paradigm for the pathogenesis of salt-dependent hypertension

Blaustein, M. P., Leenen, F. H. H., Chen, L., Golovina, V. A., Hamlyn, J. M., Pallone, T. L., Van Huysse, J. W., Zhang, J., & Wier, W. G. (2012) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00899.2011 · Cited by 285 · see citing works

Monoamine transporters and psychostimulant addiction

Howell, L. L., & Kimmel, H. L. (2007) · Biochemical Pharmacology · doi:10.1016/j.bcp.2007.08.003 · Cited by 249 · see citing works

The SEEKING mind: Primal neuro-affective substrates for appetitive incentive states and their pathological dynamics in addictions and depression

Alcaro, A., & Panksepp, J. (2011) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2011.03.002 · Cited by 240 · see citing works

Extensive early motor and non-motor behavioral deficits are followed by striatal neuronal loss in knock-in Huntington's disease mice

Hickey, M. A., Kosmalska, A., Enayati, J., Cohen, R. E., Zeitlin, S. O., Levine, M. S., & Chesselet, M. ‐. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.08.041 · Cited by 228 · see citing works

Ribosomal Protein S6 Phosphorylation in the Nervous System: From Regulation to Function

Biever, A., Valjent, E., & Puighermanal, E. (2015) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2015.00075 · Cited by 214 · see citing works

Selective Transport of Monoamine Neurotransmitters by Human Plasma Membrane Monoamine Transporter and Organic Cation Transporter 3

Duan, H., & Wang, J. (2010) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.110.170142 · Cited by 198 · see citing works

Insights into the Role of Dopamine Receptor Systems in Learning and Memory

El-Ghundi, M., O’Dowd, B. F., & George, S. R. (2007) · Reviews in the Neurosciences · doi:10.1515/revneuro.2007.18.1.37 · Cited by 169 · see citing works

Blockade of mesolimbic dopamine D3 receptors inhibits stress-induced reinstatement of cocaine-seeking in rats

Xi, Z., Gilbert, J. G., Campos, A. C., Kline, N., Ashby, C. R., Hagan, J. J., Heidbreder, C. A., & Gardner, E. L. (2004) · Psychopharmacology · doi:10.1007/s00213-004-1858-y · Cited by 163 · see citing works

Genetic analysis of the calcineurin pathway identifies members of the EGR gene family, specifically EGR3 , as potential susceptibility candidates in schizophrenia

Yamada, K., Gerber, D. J., Iwayama, Y., Ohnishi, T., Ohba, H., Toyota, T., Aruga, J., Minabe, Y., Tonegawa, S., & Yoshikawa, T. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0610765104 · Cited by 163 · see citing works

The ability of the mesocortical dopamine system to operate in distinct temporal modes

Lapish, C. C., Kroener, S., Durstewitz, D., Lavı́n, A., & Seamans, J. K. (2006) · Psychopharmacology · doi:10.1007/s00213-006-0527-8 · Cited by 153 · see citing works

DARPP-32 Is a Robust Integrator of Dopamine and Glutamate SignalsPreprint

Novere, N. L., Fernandez, É., Schiappa, R., & Girault, J.-A. (2006) · Nature Precedings · doi:10.1371/journal.pcbi.0020176 · Cited by 159 · see citing works

Dopamine Dysfunction in Borderline Personality Disorder: A Hypothesis

Friedel, R. O. (2004) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300424 · Cited by 148 · see citing works

Physical and Functional Interaction between the Dopamine Transporter and the Synaptic Vesicle Protein Synaptogyrin-3

Egaña, L. A., Cuevas, R. A., Baust, T. B., Parra‐Rivas, L. A., Leak, R. K., Hochendoner, S. J., Pena, K. A., Quiroz, M. E., Hong, W. C., Dorostkar, M. M., et al. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.4559-08.2009 · Cited by 147 · see citing works

Localization of dopamine D2 receptors on cholinergic interneurons of the dorsal striatum and nucleus accumbens of the rat

Alcantara, A. A., Chen, V., Herring, B. E., Mendenhall, J. M., & Berlanga, M. L. (2003) · Brain Research · doi:10.1016/s0006-8993(03)03165-2 · Cited by 138 · see citing works

Dopamine modulates neural networks involved in effort-based decision-making

Assadi, S. M., Yücel, M., & Pantelis, C. (2008) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2008.10.010 · Cited by 133 · see citing works

Dopaminergic neurons intrinsic to the striatum

Huot, P., & Parent, A. (2007) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2006.04430.x · Cited by 120 · see citing works

Convergent evidence for abnormal striatal synaptic plasticity in dystonia

Peterson, D. A., B, T. J. S. A., & Howard Poizner, A. (2009) · Neurobiology of Disease · doi:10.1016/j.nbd.2009.12.003 · Cited by 118 · see citing works

Phenotypic studies on dopamine receptor subtype and associated signal transduction mutants: insights and challenges from 10 years at the psychopharmacology–molecular biology interface

Waddington, J. L., O’Tuathaigh, C. M. P., O'Sullivan, G., Tomiyama, K., Koshikawa, N., & Croke, D. T. (2005) · Psychopharmacology · doi:10.1007/s00213-005-0058-8 · Cited by 112 · see citing works

Toxoplasmosis: A pathway to neuropsychiatric disorders

Tyebji, S., Seizova, S., Hannan, A. J., & Tonkin, C. J. (2018) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2018.11.012 · Cited by 111 · see citing works

A Kinetic Model of Dopamine- and Calcium-Dependent Striatal Synaptic Plasticity

Nakano, T., Doi, T., Yoshimoto, J., & Doya, K. (2010) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1000670 · Cited by 111 · see citing works

Behavioral Phenotyping and Pathological Indicators of Parkinson's Disease in C. elegans Models

Maulik, M., Mitra, S., Bult-Ito, A., Taylor, B. E., & Vayndorf, E. M. (2017) · Frontiers in Genetics · doi:10.3389/fgene.2017.00077 · Cited by 100 · see citing works

D1 Receptor Modulation of Action Potential Firing in a Subpopulation of Layer 5 Pyramidal Neurons in the Prefrontal Cortex

Seong, H. J., & Carter, A. G. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.1367-12.2012 · Cited by 100 · see citing works

D2-Like Dopamine Receptors Depolarize Dorsal Raphe Serotonin Neurons through the Activation of Nonselective Cationic Conductance

Aman, T. K., Shen, R., & Haj‐Dahmane, S. (2006) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.106.111690 · Cited by 96 · see citing works

Extensive neuroprotection by choroid plexus transplants in excitotoxin lesioned monkeys

Emerich, D. F., Thanos, C. G., Goddard, M. B., Skinner, S. J. M., Geany, M. S., Bell, W. J., Bintz, B. E., Schneider, P. A., Chu, Y., Babu, R. S., et al. (2006) · Neurobiology of Disease · doi:10.1016/j.nbd.2006.04.014 · Cited by 93 · see citing works

Transgenic mouse models for ADHD

Leo, D., & Gainetdinov, R. (2013) · Cell and Tissue Research · doi:10.1007/s00441-013-1639-1 · Cited by 74 · see citing works

Striatal Vulnerability in Huntington’s Disease: Neuroprotection Versus Neurotoxicity

Morigaki, R., & Goto, S. (2017) · Brain Sciences · doi:10.3390/brainsci7060063 · Cited by 76 · see citing works

Phosphodiesterase inhibition and modulation of corticostriatal and hippocampal circuits: Clinical overview and translational considerations

Heckman, P. R. A., Blokland, A., Bollen, E., & Prickaerts, J. (2018) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2018.02.007 · Cited by 75 · see citing works

Phosphodiesterase Inhibition and Regulation of Dopaminergic Frontal and Striatal Functioning: Clinical Implications

Heckman, P. R. A., van Duinen, M. A., Bollen, E., Nishi, A., Wennogle, L. P., Blokland, A., & Prickaerts, J. (2016) · The International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyw030 · Cited by 60 · see citing works

Cannabis-Associated Psychosis

Leweke, F. M., Gerth, C. W., & tter, J. K. (2004) · CNS Drugs · doi:10.2165/00023210-200418130-00005 · Cited by 60 · see citing works

Dysregulated intracellular signaling in the striatum in a pathophysiologically grounded model of Tourette syndrome

Rapanelli, M., Frick, L. R., Pogorelov, V. M., Ota, K. T., Abbasi, E., Ohtsu, H., & Pittenger, C. (2014) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2014.10.007 · Cited by 57 · see citing works

Synaptopathic mechanisms of neurodegeneration and dementia: Insights from Huntington’s disease

Tyebji, S., & Hannan, A. J. (2017) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2017.03.008 · Cited by 56 · see citing works

Monoamine Transporter Inhibitors and Substrates as Treatments for Stimulant Abuse

Howell, L. L., & Negus, S. S. (2014) · Advances in pharmacology · doi:10.1016/b978-0-12-420118-7.00004-4 · Cited by 56 · see citing works

The distribution of dopamine D1 receptor and μ-opioid receptor 1 receptor immunoreactivities in the amygdala and interstitial nucleus of the posterior limb of the anterior commissure: Relationships to tyrosine hydroxylase and opioid peptide terminal systems

Jacobsen, K. X., Höistad, M., Staines, W. A., & Fuxé, K. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2006.05.054 · Cited by 56 · see citing works

Repeated Cocaine Administration Decreases Calcineurin (PP2B) but Enhances DARPP-32 Modulation of Sodium Currents in Rat Nucleus Accumbens Neurons

Hu, X., Ford, K. A., & White, F. J. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300654 · Cited by 54 · see citing works

Proteomic Analysis of Hypoxia/Ischemia-Induced Alteration of Cortical Development and Dopamine Neurotransmission in Neonatal Rat

Hu, X., Rea, H. C., Wiktorowicz, J. E., & Perez-Polo, J. R. (2006) · Journal of Proteome Research · doi:10.1021/pr060209x · Cited by 52 · see citing works

Increase in A2A receptors in the nucleus accumbens after extended cocaine self-administration and its disappearance after cocaine withdrawal

Marcellino, D. J., Roberts, D. C. S., Navarro, G., Filip, M., Agnati, L. F., Lluı́s, C., Franco, R., & Fuxé, K. (2007) · Brain Research · doi:10.1016/j.brainres.2007.01.079 · Cited by 51 · see citing works

The Histamine H3 Receptor Differentially Modulates Mitogen-activated Protein Kinase (MAPK) and Akt Signaling in Striatonigral and Striatopallidal Neurons

Rapanelli, M., Frick, L. R., Horn, K. D., Schwarcz, R. C., Pogorelov, V. M., Nairn, A. C., & Pittenger, C. (2016) · Journal of Biological Chemistry · doi:10.1074/jbc.m116.731406 · Cited by 49 · see citing works

Inter-Kingdom Signaling of Stress Hormones: Sensing, Transport and Modulation of Bacterial Physiology

Boukerb, A. M., Cambronel, M., Rodrigues, S., Mesguida, O., Knowlton, R., Feuilloley, M. G. J., Zommiti, M., & Connil, N. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.690942 · Cited by 46 · see citing works

The Dopamine Agonist Bromocriptine Differentially Affects Fronto-Striatal Functional Connectivity During Working Memory

Wallace, D. L., Vytlacil, J. J., Nomura, E. M., Gibbs, S. E. B., & D’Esposito, M. (2011) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2011.00032 · Cited by 46 · see citing works

Molecular Mechanisms of Threat Learning in the Lateral Nucleus of the Amygdala

Sears, R. M., Schiff, H. C., & LeDoux, J. E. (2014) · Progress in molecular biology and translational science · doi:10.1016/b978-0-12-420170-5.00010-6 · Cited by 44 · see citing works

Sustained Extracellular Signal-Regulated Kinase 1/2 Phosphorylation in Neonate 6-Hydroxydopamine-Lesioned Rats after Repeated D1-Dopamine Receptor Agonist Administration: Implications for NMDA Receptor Involvement

Papadeas, S. T., Blake, B. L., Knapp, D. J., & Breese, G. R. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.0528-04.2004 · Cited by 45 · see citing works

Dopamine D1 Receptor in Cancer

Sobczuk, P., Łomiak, M., & Cudnoch‐Jędrzejewska, A. (2020) · Cancers · doi:10.3390/cancers12113232 · Cited by 43 · see citing works

Persistent activation of the D1R/Shp-2/Erk1/2 pathway in l-DOPA-induced dyskinesia in the 6-hydroxy-dopamine rat model of Parkinson's disease

Fiorentini, C., Savoia, P., Savoldi, D., Barbon, A., & Missale, C. (2013) · Neurobiology of Disease · doi:10.1016/j.nbd.2013.01.005 · Cited by 41 · see citing works

Dopamine receptor activation reveals a novel, kynurenate-sensitive component of striatal N-methyl-d-aspartate neurotoxicity

Pöeggeler, B., Rassoulpour, A., Wu, H., Guidetti, P., Roberts, R. C., & Schwarcz, R. M. (2007) · Neuroscience · doi:10.1016/j.neuroscience.2007.05.033 · Cited by 42 · see citing works

Opposing Regulation of Pair Bond Formation by cAMP Signaling within the Nucleus Accumbens Shell

Aragona, B. J., & Wang, Z. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.3216-07.2007 · Cited by 41 · see citing works

Repeated cocaine exposure decreases dopamine D₂‐like receptor modulation of Ca²⁺homeostasis in rat nucleus accumbens neurons

Perez, M. F., Ford, K. A., Goussakov, I., Stutzmann, G. E., & Hu, X. (2011) · Synapse · doi:10.1002/syn.20831 · Cited by 40 · see citing works

FTO: An Emerging Molecular Player in Neuropsychiatric Diseases

Annapoorna, P. K., Iyer, H., Parnaik, T., Narasimhan, H., Bhattacharya, A., & Kumar, A. (2019) · Neuroscience · doi:10.1016/j.neuroscience.2019.08.021 · Cited by 39 · see citing works

A-Kinase Anchoring Protein–Calcineurin Signaling in Long-Term Depression of GABAergic Synapses

Dacher, M., Gouty, S., Dash, S., Cox, B. M., & Nugent, F. S. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.2037-12.2013 · Cited by 38 · see citing works

Designing Functionally Selective Noncatechol Dopamine D1 Receptor Agonists with Potent In Vivo Antiparkinsonian Activity

Martini, M. L., Ray, C., Yu, X., Liu, J., Pogorelov, V. M., Wetsel, W. C., Huang, X., McCorvy, J. D., Caron, M. G., & Jin, J. J. (2019) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.9b00410 · Cited by 39 · see citing works

Dopamine D2Receptor-Activated Ca2+Signaling Modulates Voltage-Sensitive Sodium Currents in Rat Nucleus Accumbens Neurons

Hu, X., Dong, Y., Zhang, X.-F., & White, F. J. (2005) · Journal of Neurophysiology · doi:10.1152/jn.00771.2004 · Cited by 39 · see citing works

Rapid Dopaminergic Signaling by Interneurons That Contain Markers for Catecholamines and GABA in the Feeding Circuitry of Aplysia

Díaz‐Ríos, M., & Miller, M. W. (2004) · Journal of Neurophysiology · doi:10.1152/jn.00003.2004 · Cited by 39 · see citing works

Genetic substrates of psychosis in patients with Parkinson's disease: A critical review

Lenka, A., Arumugham, S. S., Christopher, R., & Pal, P. K. (2016) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2016.03.005 · Cited by 36 · see citing works

Injectable Hydrogels Providing Sustained Delivery of Vascular Endothelial Growth Factor are Neuroprotective in a Rat Model of Huntington’s Disease

Emerich, D. F., Mooney, D. J., Storrie, H., Babu, R. S., & Kordower, J. H. (2009) · Neurotoxicity Research · doi:10.1007/s12640-009-9079-0 · Cited by 34 · see citing works

Orquestic regulation of neurotransmitters on reward-seeking behavior

Arias-Carrión, Ó., Caraza-Santiago, X., Salgado-Licona, S., Salama, M., Machado, S. E. D. C., Nardi, A. E., Menéndez‐González, M., & Murillo‐Rodríguez, E. (2014) · International Archives of Medicine · doi:10.1186/1755-7682-7-29 · Cited by 33 · see citing works

The Molecular Chaperone Hsc70 Interacts with Tyrosine Hydroxylase to Regulate Enzyme Activity and Synaptic Vesicle Localization

Parra‐Rivas, L. A., Baust, T. B., Smith, A. D., Jaumotte, J. D., Zigmond, M. J., Torres, S., Leak, R. K., Pino, J. A., & Torres, G. E. (2016) · Journal of Biological Chemistry · doi:10.1074/jbc.m116.728782 · Cited by 32 · see citing works

Dynamic expression of tyrosine hydroxylase mRNA and protein in neurons of the striatum and amygdala of mice, and experimental evidence of their multiple embryonic origin

Bupesh, M., Vicario, A., Abellán, A., Desfilis, E., & Medina, L. M. (2013) · Brain Structure and Function · doi:10.1007/s00429-013-0533-7 · Cited by 30 · see citing works

Modeling and protein engineering studies of active and inactive states of human dopamine D2 receptor (D2R) and investigation of drug/receptor interactions

Salmas, R. E., Yurtsever, M., Stein, M., & Durdağı, S. (2015) · Molecular Diversity · doi:10.1007/s11030-015-9569-3 · Cited by 30 · see citing works

Kinases as Targets for Parkinson's Disease: From Genetics to Therapy

Vancraenenbroeck, R., Lobbestael, E., Maeyer, M. D., Baekelandt, V., & Taymans, J. (2011) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/187152711797247858 · Cited by 30 · see citing works

Chronic exposure to environmentally realistic levels of diuron impacts the behaviour of adult marine medaka (Oryzias melastigma)

Zhou, Y., Han, X., Bao, Y., Zhu, Z., Huang, J., Yang, C., He, C., & Zuo, Z. (2021) · Aquatic Toxicology · doi:10.1016/j.aquatox.2021.105917 · Cited by 30 · see citing works

Defining Structure–Functional Selectivity Relationships (SFSR) for a Class of Non-Catechol Dopamine D1 Receptor Agonists

Martini, M. L., Liu, J., Ray, C., Yu, X., Huang, X., Urs, A. N., Urs, N. M., McCorvy, J. D., Caron, M. G., Roth, B. L., et al. (2019) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.9b00351 · Cited by 29 · see citing works

Δ-Tetrahydrocannabinol Increases Dopamine D1-D2 Receptor Heteromer and Elicits Phenotypic Reprogramming in Adult Primate Striatal Neurons

Hasbi, A., Madras, B. K., Bergman, J., Kohut, S. J., Lin, Z., Withey, S. L., & George, S. R. (2019) · iScience · doi:10.1016/j.isci.2019.100794 · Cited by 29 · see citing works

Wiring and Volume Transmission in Rat Amygdala. Implications for Fear and Anxiety

de la Mora, M. P., Jacobsen, K. X., Crespo‐Ramírez, M., Flores‐Gracia, C., & Fuxé, K. (2008) · Neurochemical Research · doi:10.1007/s11064-008-9722-9 · Cited by 27 · see citing works

Elevated antibody binding to striatal cholinergic interneurons in patients with pediatric acute-onset neuropsychiatric syndrome

Xu, J., Frankovich, J., Liu, R.-J., Thienemann, M., Silverman, M. A., Farhadian, B., Willett, T. A., Manko, C., Columbo, L. A., Leibold, C. M., et al. (2024) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2024.07.044 · Cited by 27 · see citing works

Motor Skill Learning Is Associated with Phase-Dependent Modifications in the Striatal cAMP/PKA/DARPP-32 Signaling Pathway in Rodents

Qian, Y., Forssberg, H., & Heijtz, R. D. (2015) · PLoS ONE · doi:10.1371/journal.pone.0140974 · Cited by 26 · see citing works

Caffeine Regulates Neuronal Expression of the Dopamine 2 Receptor Gene

Stonehouse, A. H., Adachi, M., Walcott, E. C., & Jones, F. S. (2003) · Molecular Pharmacology · doi:10.1124/mol.64.6.1463 · Cited by 26 · see citing works

Cyclic AMP responsive element binding protein phosphorylation and persistent expression of levodopa‐induced response alterations in unilateral nigrostriatal 6‐OHDA lesioned rats

Oh, J. D., Chartisathian, K., Ahmed, S. M., & Chase, T. N. (2003) · Journal of Neuroscience Research · doi:10.1002/jnr.10629 · Cited by 25 · see citing works

Zebrafish as a potential non-traditional model organism in translational bipolar disorder research: Genetic and behavioral insights

Canzian, J., Gonçalves, F. L. S., Müller, T. E., Franscescon, F., Santos, L. W., Adedara, I. A., & Rosemberg, D. B. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104620 · Cited by 23 · see citing works

Synaptic Proteins in the Postmortem Anterior Cingulate Cortex in Schizophrenia: Relationship to Treatment and Treatment Response

Barksdale, K. A., Lahti, A. C., & Roberts, R. C. (2014) · Neuropsychopharmacology · doi:10.1038/npp.2014.57 · Cited by 22 · see citing works

Analysis of Cell Type-specific Expression of CK1ε in Various Tissues of Young Adult BALB/c Mice and in Mammary Tumors of SV40 T-Ag-transgenic Mice

Utz, A. C., Hirner, H., Blatz, A., Hillenbrand, A., Schmidt, B., Deppert, W., Henne‐Bruns, D., Fischer, D., Thal, D. R., Leithäuser, F., et al. (2009) · Journal of Histochemistry & Cytochemistry · doi:10.1369/jhc.2009.954628 · Cited by 22 · see citing works

Proteomic Analysis of Alterations Induced by Perinatal Hypoxic–Ischemic Brain Injury

Rosenkranz, K., May, C., Meier, C., & Marcus, K. (2012) · Journal of Proteome Research · doi:10.1021/pr3005869 · Cited by 22 · see citing works

Activation of dopamine D1 receptors blocks phencyclidine‐induced neurotoxicity by enhancing N‐methyl‐D‐aspartate receptor‐mediated synaptic strength

Lei, G., Anastasio, N. C., Fu, Y., Neugebauer, V., & Johnson, K. M. (2009) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2009.06030.x · Cited by 21 · see citing works

Corticostriatal Plastic Changes in Experimental L-DOPA-Induced Dyskinesia

Ghiglieri, V., Bagetta, V., Pendolino, V., Picconi, B., & Calabresi, P. (2012) · Parkinson s Disease · doi:10.1155/2012/358176 · Cited by 21 · see citing works

Association of calcineurin A gamma subunit (PPP3CC) and early growth response 3 (EGR3) gene polymorphisms with susceptibility to schizophrenia in a Japanese population

Kyogoku, C., Yanagi, M., Nishimura, K., Sugiyama, D., Morinobu, A., Fukutake, M., Maeda, K., Shirakawa, O., Kuno, T., & Kumagai, S. (2011) · Psychiatry Research · doi:10.1016/j.psychres.2009.11.003 · Cited by 20 · see citing works

The brain/body-in-the-world system is cognitive science’s study object for the twenty-first century / El sistema cerebro/cuerpo-en-el-mundo es el objeto de estudio de la ciencia cognitiva en el siglo XXI

Rossi, A., Grasso‐Cladera, A., Luarte, N., Riillo, A., & Parada, F. J. (2019) · Studies in Psychology Estudios de Psicología · doi:10.1080/02109395.2019.1596704 · Cited by 20 · see citing works

Thermoluninescenct in LiF: sensitization useful at low exposures.

Mayhugh, M. R., & Fullerton, G. D. (1975) · PubMed · Cited by 20 · see citing works

Noncoding RNA Regulation of Dopamine Signaling in Diseases of the Central Nervous System

Carrick, W. T., Burks, B., Cairns, M. J., & Kocerha, J. (2016) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2016.00069 · Cited by 19 · see citing works

Genetic deletion of PDE10A selectively impairs incentive salience attribution and decreases medium spiny neuron excitability

Piccart, E., Backer, J. D., Gall, D., Lambot, L., Raes, A. L., Vanhoof, G., Schiffmann, S. N., & D’Hooge, R. (2014) · Behavioural Brain Research · doi:10.1016/j.bbr.2014.03.016 · Cited by 19 · see citing works

Atomistic molecular dynamics simulations of typical and atypical antipsychotic drugs at the dopamine D2 receptor (D2R) elucidates their inhibition mechanism

Salmas, R. E., Yurtsever, M., & Durdağı, S. (2016) · Journal of Biomolecular Structure and Dynamics · doi:10.1080/07391102.2016.1159986 · Cited by 17 · see citing works

DARPP-32 expression in rat brain after electroconvulsive stimulation.

Rosa, D. V., Souza, R. P., Souza, B. R., Motta, B. S., Caetano, F., Jornada, L. K., Feier, G., Gomez, M., Quevedo, J., & Romano-Silva, M. (2007) · Brain Research · doi:10.1016/j.brainres.2007.08.043 · Cited by 15 · see citing works

Role of Dopamine Type 1 Receptors and Dopamine- and cAMP-Regulated Phosphoprotein Mr 32 kDa in Δ9-Tetrahydrocannabinol–Mediated Induction of ΔFosB in the Mouse Forebrain

Lazenka, M. F., Tomarchio, A. J., Lichtman, A. H., Greengard, P., Flajolet, M., Selley, D. E., & Sim‐Selley, L. J. (2015) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.115.224428 · Cited by 16 · see citing works

Suppression of outward K+ currents by activating dopamine D1 receptors in rat retinal ganglion cells through PKA and CaMKII signaling pathways

Li, Q., Wu, N., Cui, P., Gao, F., Qian, W., Miao, Y., Sun, X., & Wang, Z. (2016) · Brain Research · doi:10.1016/j.brainres.2016.01.039 · Cited by 16 · see citing works

Dopamine transporter trafficking is regulated by neutral sphingomyelinase 2/ceramide kinase

Won, J. H., Kim, S. K., Shin, I. C., Ha, H. C., Jang, J. M., Back, M. J., & Kim, D. K. (2018) · Cellular Signalling · doi:10.1016/j.cellsig.2018.01.006 · Cited by 16 · see citing works

Sex and the dopaminergic system: Insights from addiction studies

Woodcock, E. A., Zakiniaeiz, Y., Morris, E. D., & Cosgrove, K. (2020) · Handbook of clinical neurology · doi:10.1016/b978-0-444-64123-6.00011-4 · Cited by 14 · see citing works

No association between PPP3CC and schizophrenia in the Chinese population

Xi, Z., Yu, L., Shi, Y., Wei, Q., Zheng, Y., Zhang, J., He, G., Yao, W., Zhang, K., Gu, N., et al. (2006) · Schizophrenia Research · doi:10.1016/j.schres.2006.10.012 · Cited by 15 · see citing works

Immunohistochemical localization of DARPP-32 in the brain and spinal cord of anuran amphibians and its relation with the catecholaminergic system

López, J. M., Morona, R., & González, A. (2010) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2010.09.004 · Cited by 15 · see citing works

Basal and cocaine-induced sex differences in the DARPP-32-mediated signaling pathway

Zhou, L., Nazarian, A., Sun, W., Jenab, S., & Quiñones-Jenab, V. (2008) · Psychopharmacology · doi:10.1007/s00213-008-1388-0 · Cited by 15 · see citing works

Sleep and Pain: A Role for the Anterior Cingulate Cortex, Nucleus Accumbens, and Dopamine in the Increased Pain Sensitivity Following Sleep Restriction

Sardi, N. F., Pescador, A. C., de Azevedo, E. M., Pochapski, J. A., Kukolj, C., Spercoski, K. M., Martino‐Andrade, A. J., Cunha, C. D., & Fischer, L. (2023) · Journal of Pain · doi:10.1016/j.jpain.2023.08.014 · Cited by 13 · see citing works

Hippocampal receptor complexes paralleling LTP reinforcement in the spatial memory holeboard test in the rat

Subramaniyan, S., Hajali, V., Scherf, T., Sase, S., Sialana, F. J., Gröger, M., Bennett, K. L., Pollak, A. J., Li, L., Korz, V., et al. (2015) · Behavioural Brain Research · doi:10.1016/j.bbr.2015.01.036 · Cited by 13 · see citing works

Activation of dopamine D1 receptors enhances the temporal summation and excitability of rat retinal ganglion cells

Cui, P., Li, X., Zhao, Y., Li, Q., Gao, F., Li, L.-Z., Yin, N., Sun, X., & Wang, Z. (2017) · Neuroscience · doi:10.1016/j.neuroscience.2017.04.046 · Cited by 13 · see citing works

Interaction of Cdk5 and cAMP/PKA Signaling in the Mediation of Neuropsychiatric and Neurodegenerative Diseases

Hu, Y., Pan, S., & Zhang, H. (2017) · Advances in neurobiology · doi:10.1007/978-3-319-58811-7_3 · Cited by 13 · see citing works

Immunohistochemical Localization of DARPP-32 in the Brain of Two Lungfishes: Further Assessment of Its Relationship with the Dopaminergic System

López, J. M., Morona, R., & González, A. (2017) · Brain Behavior and Evolution · doi:10.1159/000481929 · Cited by 13 · see citing works

Combination of behaviorally sub-effective doses of glutamate NMDA and dopamine D1 receptor antagonists impairs executive function

Desai, S. J., Allman, B. L., & Rajakumar, N. (2017) · Behavioural Brain Research · doi:10.1016/j.bbr.2017.01.030 · Cited by 11 · see citing works

Phosphodiesterase 4 inhibition affects both the direct and indirect pathway: an electrophysiological study examining the tri-phasic response in the substantia nigra pars reticulata

Heckman, P. R. A., Schweimer, J. V., Sharp, T., Prickaerts, J., & Blokland, A. (2017) · Brain Structure and Function · doi:10.1007/s00429-017-1518-8 · Cited by 11 · see citing works

The generation of midbrain dopaminergic neurons

Blaess, S., Stott, S., & Ang, S. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-814405-3.00017-5 · Cited by 12 · see citing works

Dopaminergic Modulation of Prefrontal Cortex Network Dynamics

Durstewitz, D. (2007) · Springer eBooks · doi:10.1007/978-0-387-72256-6_15 · Cited by 11 · see citing works

Locomotor Effects of a D1R Agonist Are DARPP-32 Dependent in Adult but not Weanling Mice

Scott, L., Forssberg, H., Aperia, A. C., & Heijtz, R. D. (2005) · Pediatric Research · doi:10.1203/01.pdr.0000180553.23507.31 · Cited by 10 · see citing works

Reward-Seeking Behavior and Addiction: Cause or Cog?

Arias-Carrión, Ó., & Salama, M. (2012) · Current Drug Abuse Reviews · doi:10.2174/1874473711205030178 · Cited by 10 · see citing works

The Neurobiology of Dopamine Signaling—Correction

(2004) · Archives of Neurology · doi:10.1001/archneur.61.8.1180

Neurobiology of DOPA as a neurotransmitter

Misu, Y. (2006)

[Some recent findings on the biochemistry of synaptic transmissions].

Skoda, C. (1961) · PubMed

Dopamine and slow synaptic transmission

Wen-gen, Z. (2001)

Biochemical evidence for a transmitter role of dopamine in the rat hippocamus

Bischoff, S. F., Scatton, B., & Korf, J. (1979) · Brain Research · doi:10.1016/0006-8993(79)90056-8 · Cited by 109 · see citing works