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Cited by 320Autism Spectrum Disorder ResearchChild Nutrition and Feeding IssuesGenetics and Neurodevelopmental Disorders

The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.

Factor Analysis of Restricted and Repetitive Behaviors in Autism Using the Autism Diagnostic Interview-R

Cuccaro, Michael L., Shao, Yujan, Grubber, Janet, Slifer, Michael, Wolpert, Chantelle M., Donnelly, Shannon L., Abramson, Ruth K., Ravan, Sarah A., Wright, Harry H., DeLong, G. Robert, Pericak-Vance, Margaret A.·2003·Child Psychiatry and Human Development
DOI 10.1023/a:1025321707947
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Abstract

The current study examined the factor structure of restricted and repetitive behaviors (RRB) in children with autism. Factor extraction procedures of 12 items from the Autism Diagnostic Interview-Revised (ADI-R) were applied in N = 207 individuals with autism. Two interpretable factors were identified: Factor 1--repetitive sensory motor actions and Factor 2--resistance to change. There was a significant negative correlation between an index of level of adaptive functioning and Factor 1. Intraclass correlations were not significant for either factor in a subset of families with two or more siblings with autism (multiplex). No differences in scores were apparent for either factor when multiplex families and families containing only one affected individual with autism (singleton) were compared. RRB in autism are represented by two distinct factors which may reflect two separate groups within autism. Defining subgroups within autism will allow for reduction of clinical heterogeneity and enhance our ability to dissect the genetic etiology of this complex disorder.

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Crossref · 10.1023/a:1025321707947

Cites

24 of 24 references verified0 citation errors · 0 not checkable

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Show all 24 references

Research works printed but not linked: 2

  1. Bodfish JW, Symons F, Lewis M: The Repetitive Behavior Scales: A test manual, Morganton, North Carolina, Western Carolina Center Research Reports; 1999.
  2. Sparrow, S. S., Balla, D., and Cicchetti, D. Vineland Adaptive Behavior Scales, Interview Edition, Survey Form. 1984. Circle Pines, MN, American Guidance Service. (GENERIC) Ref Type: Pamphlet

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Metadata

Authors
Cuccaro, M. L., Shao, Y., Grubber, J., Slifer, M., Wolpert, C. M., Donnelly, S. L., Abramson, R. K., Ravan, S. A., Wright, H. H., DeLong, G. R., & Pericak-Vance, M. A.
Affiliations
  • Duke University (US)
  • Duke Medical Center (US)
  • University of South Carolina (US)
Corresponding author
Cuccaro, Michael L.
ORCID
Venue
Child Psychiatry and Human Development
Publisher
Springer Science and Business Media LLC
Published
2003-09
Volume
34
Issue
1
Pages
3-17
ISSN
  • 0009-398X (ISSN-L)
  • 1573-3327
DOI
10.1023/a:1025321707947
OpenAlex
W1241721946
Semantic Scholar
fe72d21df02a060f6a663aaa77439d0e788eda67
Cited by
299
References
24
Citations by year
2026: 4 · 2025: 3 · 2024: 15 · 2023: 7 · 2022: 20 · 2021: 31 · 2020: 10 · 2019: 9 · 2018: 13 · 2017: 4 · 2016: 9 · 2015: 23 · 2014: 16 · 2013: 25 · 2012: 16
FWCI
3.43
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • Child Psychiatry & Human Development (publishedVersion)
  • PubMed (publishedVersion)
Funders
National Institute of Neurological Disorders and Stroke (R01 NS36768, R01NS036768)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
  • Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
Keywords
restricted and repetitive behaviors, autism spectrum disorder, factor structure, resistance to change, adaptive behavior, multiplex families, autism subgroups, clinical heterogeneity, genetic etiology
MeSH terms
Adolescent, Adult, Autistic Disorder, Child, Child, Preschool, Factor Analysis, Statistical, Female, Humans, Interview, Psychological, Male, Phenotype, Stereotyped Behavior

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