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Culturally Grounded Substance Use Prevention: An Evaluation of the keepin' it R.E.A.L. Curriculum
Abstract
This paper reports on the evaluation of a culturally grounded prevention intervention targeting substance use among urban middle-school students. The curriculum consists of 10 lessons promoting antidrug norms and teaching resistance and other social skills, reinforced by booster activities and a media campaign. Three versions were delivered: Mexican American, combined African American and European American, and Multicultural. Thirty-five middle schools were randomly assigned to 1 of the 3 versions or the control. Students completed baseline and follow-up questionnaires over a 2-year period (total 6,035 respondents). Analyses utilizing a generalized estimating equations approach assessed the overall effectiveness of cultural grounding and the cultural matching hypothesis. Support was found for the intervention's overall effectiveness, with statistically significant effects on gateway drug use as well as norms, attitudes, and resistance strategies but with little support for the cultural matching hypothesis. Specific contrasts found the Mexican American and Multicultural versions impacted the most outcomes.
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“Culturally targeted substance abuse interventions may impact initiation of substance use and help in the treatment of abuse (Hetch et al., 2003; Unger, 2012).”
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“To achieve significant and lasting reduction in youth substance use, prevention efforts should target adolescent peer cluster subcultures that give substance use its meaning ( Hecht et al, 2003 ; Kulis et al, 2005 ).”
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“This registry includes school-based interventions such as Life Skills Training (Botvin & Griffin, 2004), Keepin’ it REAL (Hecht et al., 2003), and All Stars (Hansen, 1996), which have proven to be effective.”
MethodMiller-Day, M. A., & Hecht, M. L. (2017) · Drugs Education Prevention and Policy · doi:10.1080/09687637.2017.1288685
“The D.A.R.E. version of the curriculum is based on the original kiR curriculum created by Hecht and others that was evaluated in a RCT and demonstrated positive effects (Hecht, Graham, & Elek, 2006; Hecht et al., 2003).”
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“It is also not enough to utilize generic messaging and programming for this population, and programming needs to be tailored and grounded within the cultural contexts in which these youth are operating (Hecht et al., 2003).”
Self-citationRulison, K. L., Weaver, G. M., Milroy, J. J., Beamon, E. R., Kelly, S. E., Ameeni, A., Juma, A., Abualgasim, F., Husain, J., & Wyrick, D. L. (2024) · JMIR Formative Research · doi:10.2196/58322
“The core D.A.R.E curriculum has also historically aimed to change expectancies regarding consequences [15,16] and the current lessons incorporate content that aims to influence beliefs about the consequences of discrimination, included as a targeted mediator in both models.”
BackgroundMarsiglia, F. F., Huang, C.-K., Williams, J. H., Munyuwiny, S., Makunyane, L., Molobe, I. D., Freeman, R. J., Kulis, S., Ogbonnaya, I. N., & Lightfoot, E. (2025) · Substance Use & Addiction Journal · doi:10.1177/29767342251350757
Self-citationMarsiglia, F. F., Libisch, C., Kulis, S., & Ruiz, P. (2025) · Journal of Prevention · doi:10.1007/s10935-025-00886-3
Self-citationKigali Charity School Analyzed Through an Implementation Science Framework
Fronk, A. T. (2021) · Digital Commons - USU (Utah State University) · doi:10.26076/27a9-f9bc
Hodges, J. C., Pizarro, E. P., Bolaños, M. F., McSweeney, M. L., Marsiglia, F. F., & Salas‐Wright, C. P. (2026) · Child and Adolescent Social Work Journal · doi:10.1007/s10560-025-01077-z
“It has a strong evidence base for strengthening anti-substance norms and delaying onset of use (Hecht et al., 2003). ki R is based on communication theory and the original intervention is grounded in the Mexican-American culture of the Southwest U.S. (Gosin et al., 2003).”
Self-citationOkamura, K. H., Cramer, M. A., Palafu, T., Helm, S., Dalisay, F. S., Primack, Z., Ching, D. L. C., Goshgarian-Miller, S., Liu, M., Chin, S. K., et al. (2026) · Substance Abuse Treatment Prevention and Policy · doi:10.1186/s13011-026-00715-8
“A central goal of HP is to teach students resistance skills to respond to drug offers in a way that is relevant to their community and cultural background [17].”
Fitzgerald, A., James, P. D., Hollywood, E., Comiskey, C. M., Reilly, R., Annunziata, K. N., & Kelly, P. (2026) · Global Implementation Research and Applications · doi:10.1007/s43477-026-00235-4
Wang, Y., Zhang, Y., Yan, J., Huang, Q., Jelsma, E. B., Zhao, Z., Zhao, J., Cham, H., Alegria, M. M., & Yip, T. (2026) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2026.113372
Metadata
- Authors
- Hecht, M. L., Marsiglia, F. F., Elek, E., Wagstaff, D. A., Kulis, S., Dustman, P., & Miller-Day, M.
- Affiliations
- Pennsylvania State University (US)
- Arizona State University (US)
- Corresponding author
- Hecht, Michael L.
- Venue
- Prevention Science
- Published
- 2003-12
- Volume
- 4
- Issue
- 4
- Pages
- 233-248
- ISSN
- 1389-4986 (ISSN-L)
- 1573-6695
- OpenAlex
- W1577230560
- Cited by
- 383
- References
- 69
- Citations by year
- 2026: 6 · 2025: 5 · 2024: 7 · 2023: 11 · 2022: 17 · 2021: 7 · 2020: 48 · 2019: 16 · 2018: 16 · 2017: 16 · 2016: 22 · 2015: 14 · 2014: 15 · 2013: 26 · 2012: 20
- FWCI
- 5.85
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Prevention Science (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Centers for Disease Control and Prevention
- National Institute on Drug Abuse (R01 DA 05629, R01DA005629)
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Youth, Drugs, and Violence
- Social Sciences › Sociology and Political Science › Crime Patterns and Interventions
- Keywords
- substance use prevention, cultural grounding, Mexican American students, African American students, European American students, junior high school students, resistance strategies, social skills, media campaigns, multicultural curriculum
- MeSH terms
- Adolescent, Culture, Curriculum, Ethnicity, Health Education, Humans, Surveys and Questionnaires, School Health Services, United States, Program Evaluation, Substance-Related Disorders, Self Efficacy
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