Perceived quality of life in schizophrenia: Relationships to sleep quality
Abstract
We examined the relationship between perceived quality of life (QOL) and subjective quality of sleep among schizophrenia patients, and its relation to symptom severity, side effects and emotional distress. One hundred and forty five schizophrenia patients were comprehensively evaluated with standardized measures of symptom severity, adverse effects, emotional distress, QOL, and sleep quality (the Pittsburgh Sleep Quality Index, PSQI). Partial correlation and multiple regression analyses were performed. Poor sleepers reported lower mean scores on all QOL domains, they were more depressed and distressed, and had more adverse effects to medications with concomitant distress than good sleepers. The negative relationship between complaints of poor sleep quality and QOL measures remained significant when the confounding effect of depression, side effects, and distress was partialled from the correlation matrix. Daytime dysfunction (a component of the PSQI) accounted for 12.6% of the variance in QOL index scores. Thus, poor QOL reported by schizophrenia patients is substantially associated with poor sleep quality. This association appears both independently and synergistically with depression, distress and side effects of medications.
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One smaller study (n = 145) found no direct link between self-reported sleep quality and positive symptoms.
“although one smaller study (n = 145) found no direct link between self-reported sleep quality and positive symptoms (Ritsner, Kurs, Ponizovsky, & Hadjez, 2004).”
From The role of sleep dysfunction in the occurrence of delusions and hallucinations: A systematic review (2015) · cites this paper as Ritsner, Kurs, Ponizovsky, & Hadjez, 2004
Cites
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MethodSleep and circadian rhythm dysregulation in schizophrenia
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“, 1999), contribute to lower subjective quality of life (Ritsner et al., 2004; Hofstetter et al., 2005), to be a moderate but significant predictor for relapse (Chemerinski et al.”
BackgroundSleep disturbances in childhood-onset schizophrenia
Mattai, A. A., Tossell, J., Greenstein, D. K., Addington, A., Clasen, L. S., Gornick, M. C., Seal, J., Inoff-Germain, G., Gochman, P. A., Lenane, M., et al. (2006) · Schizophrenia Research · doi:10.1016/j.schres.2006.04.020 · Cited by 27 · see citing works
- Authors
- Ritsner, M., Kurs, R., Ponizovsky, A., & Hadjez, J.
- Affiliations
- Sha'ar Menashe Mental Health Center (IL)
- Corresponding author
- Ritsner, Michael
- ORCID
- Kurs, Rena
- Venue
- Quality of Life Research
- Published
- 2004-05
- Volume
- 13
- Issue
- 4
- Pages
- 783-791
- ISSN
- 0962-9343 (ISSN-L)
- 1573-2649
- OpenAlex
- W1965458709
- Cited by
- 156
- References
- 3
- Citations by year
- 2026: 5 · 2025: 5 · 2024: 10 · 2023: 5 · 2022: 8 · 2021: 6 · 2020: 14 · 2019: 10 · 2018: 6 · 2017: 6 · 2016: 10 · 2015: 9 · 2014: 4 · 2013: 10 · 2012: 5
- FWCI
- 4.18
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Quality of Life Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
- Keywords
- schizophrenia, quality of life, sleep quality, daytime dysfunction, depression, emotional distress, antipsychotic adverse effects, Pittsburgh Sleep Quality Index, symptom severity
- MeSH terms
- Adolescent, Adult, Aged, Depression, Humans, Israel, Longitudinal Studies, Middle Aged, Psychiatric Status Rating Scales, Psychometrics, Quality of Life, Schizophrenia, Schizophrenic Psychology, Severity of Illness Index, Sleep Deprivation, Sickness Impact Profile
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