The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
A Critical Appraisal of Vitiligo Etiologic Theories. Is Melanocyte Loss a Melanocytorrhagy?
Open accessAbstract
Common generalized vitiligo is an acquired depigmenting disorder characterized by a chronic and progressive loss of melanocytes from the epidermis and follicular reservoir. However, the mechanism of melanocyte disappearance has never been clearly understood, and the intervention of cellular and humoral autoimmune phenomena as primary events remains unproven. In this review, is discussed the data supporting the major theories of vitiligo, namely melanocyte destruction (autoimmune, neural and impaired redox status) and melanocyte inhibition or defective adhesion. Based on recent morphologic findings in vivo supporting a chronic detachment and transepidermal loss of melanocytes in common generalized vitiligo, a new theory is suggested proposing melanocytorrhagy as the primary defect underlying melanocyte loss, integrating most of the possible triggering/precipitating/enhancing effects of other known factors.
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van Elsas, A., Hurwitz, A. A., & Allison, J. P. (1999) · The Journal of Experimental Medicine · doi:10.1084/jem.190.3.355 · Cited by 1,020
Apoptosis regulators and responses in human melanocytic and keratinocytic cells
Bowen, A. R., Hanks, A. N., Allen, S. M., Alexander, A., Diedrich, M. J., & Grossman, D. (2003) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.2003.12010.x · Cited by 149
Cited by
Vitiligo: A comprehensive overview
Alikhan, A., Felsten, L. M., Daly, M., & Petronic-Rosic, V. (2011) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2010.11.061 · Cited by 708
The definition and assessment of vitiligo: a consensus report of the Vitiligo European Task Force
Taïeb, A., Picardo, M., & members, O. B. O. T. O. V. (2007) · Pigment Cell Research · doi:10.1111/j.1600-0749.2006.00355.x · Cited by 517
Self-citationAutocrine and paracrine regulation of melanocytes in human skin and in pigmentary disorders
Imokawa, G. (2004) · Pigment Cell Research · doi:10.1111/j.1600-0749.2003.00126.x · Cited by 369
Shi, Q., Zhang, W., Guo, S., Jian, Z., Li, S., Li, K., Ge, R., Dai, W., Wang, G., Gao, T., et al. (2016) · Cell Death & Differentiation · doi:10.1038/cdd.2015.117 · Cited by 117
Ling, Y., Gong, Q., Xiong, X., Sun, L., Zhao, W., Zhu, W., & Lu, Y. (2017) · Oncotarget · doi:10.18632/oncotarget.17654 · Cited by 30
Metadata
- Authors
- Gauthier, Y., Andre, M. C., & Taïeb, A.
- Venue
- Pigment Cell Research
- Publisher
- Wiley
- Published
- 2003-07-15
- Volume
- 16
- Issue
- 4
- Pages
- 322-332
- ISSN
- 0893-5785 (ISSN-L)
- 1600-0749
- OpenAlex
- W1995134644
- Cited by
- 299
- References
- 2
- FWCI
- 2.90
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Gauthier, Y., Andre, M. C., & Taïeb, A. (2003). A Critical Appraisal of Vitiligo Etiologic Theories. Is Melanocyte Loss a Melanocytorrhagy? Pigment Cell Research. https://doi.org/10.1034/j.1600-0749.2003.00070.x
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