Causation and pathogenesis of periodontal disease

Kinane, Denis F.

doi:10.1034/j.1600-0757.2001.22250102.x

Cited by 558Oral microbiology and periodontitis researchPeriodontal Regeneration and TreatmentsDental Research and COVID-19

Causation and pathogenesis of periodontal disease

Kinane, Denis F.·2001·Periodontology 2000

DOI 10.1034/j.1600-0757.2001.22250102.x

Open this paper in CoChat — free account

Integrity signals

Registry

Crossref · 10.1034/j.1600-0757.2001.22250102.x

Cites

90 of 90 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Cardiovascular disease demonstrates a close association with oral infection.
“As such, cardiovascular disease demonstrates a close association with oral infection.203, 204”
From The oral microbiome: Role of key organisms and complex networks in oral health and disease (2021) · cites this paper as [203]

Experimental gingivitis in man
Löe, H., Theilade, E., & Jensen, S. B. (1965) · The Journal of Periodontology · doi:10.1902/jop.1965.36.3.177 · Cited by 3,481 · see citing works
The Bacterial Etiology of Destructive Periodontal Disease: Current Concepts
Socransky, S. S., & Haffajee, A. D. (1992) · Journal of Periodontology · doi:10.1902/jop.1992.63.4s.322 · Cited by 1,203 · see citing works
The interleukin‐1 genotype as a severity factor in adult periodontal disease
Kornman, K. S., Crane, A., Wang, H., Giovlne, F. S. D., Newman, M. G., Pirk, F. W., Wilson, T. G., Higginbottom, F. L., & Duff, G. W. (1997) · Journal Of Clinical Periodontology · doi:10.1111/j.1600-051x.1997.tb01187.x · Cited by 1,180 · see citing works
Assessment of Risk for Periodontal Disease. I. Risk Indicators for Attachment Loss
Grossi, S. G., Zambon, J. J., Ho, A. W., Koch, G. G., Dunford, R. G., Machtei, E. E., Norderyd, O. M., & Genco, R. J. (1994) · Journal of Periodontology · doi:10.1902/jop.1994.65.3.260 · Cited by 1,127 · see citing works
Pathogenesis of inflammatory periodontal disease. A summary of current work.
Rc, P., & Schroeder, H. E. (1976) · PubMed · Cited by 1,102 · see citing works
Experimental gingivitis in man: II. A Longitudinal Clinical and Bacteriological Investigation
Theilade, E., Wright, W. H., Jensen, S. B., & Löe, H. (1966) · Journal of Periodontal Research · doi:10.1111/j.1600-0765.1966.tb01842.x · Cited by 1,038 · see citing works
A study of the bacteria associated with advancing periodontitis in man
Tanner, A. C. R., Haffer, C., Bratthall, G., Visconti, R. A., & Socransky, S. S. (1979) · Journal Of Clinical Periodontology · doi:10.1111/j.1600-051x.1979.tb01931.x · Cited by 918 · see citing works
Destructive Periodontal Disease in Adults 30 Years of Age and Older in the United States, 1988‐1994
Albandar, J. M., Brunelle, J. A., & Kingman, A. (1999) · Journal of Periodontology · doi:10.1902/jop.1999.70.1.13 · Cited by 793 · see citing works
Assessment of Risk for Periodontal Disease. II. Risk Indicators for Alveolar Bone Loss
Grossi, S. G., Genco, R. J., Machtet, E. E., Ho, A. W., Koch, G. G., Dunford, R. G., Zambon, J. J., & Hausmann, E. (1995) · Journal of Periodontology · doi:10.1902/jop.1995.66.1.23 · Cited by 735 · see citing works
New concepts of destructive periodontal disease
Socransky, S. S., Haffajee, A. D., Goodson, J. M., & Lindhe, J. (1984) · Journal Of Clinical Periodontology · doi:10.1111/j.1600-051x.1984.tb01305.x · Cited by 735 · see citing works
The predominant cultivable microbiota of active and inactive lesions of destructive periodontal diseases
Dzink, J. L., Socransky, S. S., & Haffajee, A. D. (1988) · Journal Of Clinical Periodontology · doi:10.1111/j.1600-051x.1988.tb01590.x · Cited by 714 · see citing works
Relative distribution of bacteria at clinically healthy and periodontally diseased sites in humans*
Listgarten, M. A., & Helldén, L. B. (1978) · Journal Of Clinical Periodontology · doi:10.1111/j.1600-051x.1978.tb01913.x · Cited by 700 · see citing works
Current View of Risk Factors for Periodontal Diseases
Genco, R. J. (1996) · Journal of Periodontology · doi:10.1902/jop.1996.67.10s.1041 · Cited by 686 · see citing works
The host response to the microbial challenge in periodontitis: assembling the players
Kornman, K. S., Page, R. C., & Tonetti, M. S. (1997) · Periodontology 2000 · doi:10.1111/j.1600-0757.1997.tb00191.x · Cited by 652 · see citing works
The microbial challenge in periodontitis
Darveau, R. P., Tanner, A. C. R., & Page, R. C. (1997) · Periodontology 2000 · doi:10.1111/j.1600-0757.1997.tb00190.x · Cited by 633 · see citing works
Evidence for Cigarette Smoking as a Major Risk Factor for Periodontitis
Haber, J., Wattles, J., Crowley, M., Mandell, R. L., JOSHIPURA, K. J., & Kent, R. (1993) · Journal of Periodontology · doi:10.1902/jop.1993.64.1.16 · Cited by 602 · see citing works
A Dictionary of Epidemiology.
Last, J. M. (1989) · Biometrics · doi:10.2307/2531713 · Cited by 577 · see citing works
Actinobacillus actinomycetemcomitans in Human Periodontal Disease: Prevalence in Patient Groups and Distribution of Biotypes and Serotypes Within Families
Zambon, J. J., Christersson, L. A., & Slots, J. (1983) · Journal of Periodontology · doi:10.1902/jop.1983.54.12.707 · Cited by 457 · see citing works
Cytokines and prostaglandins in immune homeostasis and tissue destruction in periodontal disease
Gemmell, E., Marshall, R. I., & Seymour, G. J. (1997) · Periodontology 2000 · doi:10.1111/j.1600-0757.1997.tb00194.x · Cited by 419 · see citing works
Progression of periodontal disease in adult subjects in the absence of periodontal therapy
Lindhe, J., Haffaiee, A. D., & Socransky, S. S. (1983) · Journal Of Clinical Periodontology · doi:10.1111/j.1600-051x.1983.tb01292.x · Cited by 418 · see citing works
On the prevention of caries and periodontal disease
Axelsson, P., Lindhe, J., & Nyström, B. (1991) · Journal Of Clinical Periodontology · doi:10.1111/j.1600-051x.1991.tb01131.x · Cited by 396 · see citing works
Periodontal Findings in Adult Twins
Michalowicz, B. S., Aeppli, D. M., Virag, J. G., Klump, D. G., Hinrichs, E., Segal, N. L., Bouchard, T. J., & Pihlstrom, B. L. (1991) · Journal of Periodontology · doi:10.1902/jop.1991.62.5.293 · Cited by 386 · see citing works
Evidence of bacterial etiology: a historical perspective
Socransky, S. S., & Haffajee, A. D. (1994) · Periodontology 2000 · doi:10.1111/j.1600-0757.1994.tb00016.x · Cited by 375 · see citing works
Cigarette smoking as risk factor in chronic periodontal disease
Bergström, J. (1989) · Community Dentistry And Oral Epidemiology · doi:10.1111/j.1600-0528.1989.tb00626.x · Cited by 363 · see citing works
Periodontal Diseases: Microbial Factors
Zambon, J. J. (1996) · Annals of Periodontology · doi:10.1902/annals.1996.1.1.879 · Cited by 355 · see citing works
Prevalence, extent, severity and progression of periodontal disease
Brown, L. J., & Löe, H. A. (1993) · Periodontology 2000 · doi:10.1111/j.1600-0757.1993.tb00220.x · Cited by 347 · see citing works
Cigarette Smoking Increases the Risk for Subgingival Infection With Periodontal Pathogens
Zambon, J. J., Grossi, S. G., Machtei, E. E., Ho, A. W., Dunford, R. G., & Genco, R. J. (1996) · Journal of Periodontology · doi:10.1902/jop.1996.67.10s.1050 · Cited by 332 · see citing works
Influence of risk factors on the pathogenesis of periodontitis
Salvi, G. E., Lawrence, H. P., Offenbacher, S., & Beck, J. D. (1997) · Periodontology 2000 · doi:10.1111/j.1600-0757.1997.tb00197.x · Cited by 279 · see citing works
Effect of cigarette smoking on periodontal healing following surgical therapy
Preber, H., & Bergström, J. (1990) · Journal Of Clinical Periodontology · doi:10.1111/j.1600-051x.1990.tb01098.x · Cited by 273 · see citing works
The capability of Actinobacillus actinomycetemcomitans, Bacteroides gingivalis and Bacteroides intermedius to indicate progressive periodontitis; a retrospective study
Bragd, L., Dahlén, G., Wikström, M. B., & Slots, J. (1987) · Journal Of Clinical Periodontology · doi:10.1111/j.1600-051x.1987.tb00949.x · Cited by 265 · see citing works
Clinical, microbiological and immunological features of subjects with destructive periodontal diseases
Haffajee, A. D., Socransky, S. S., Dzink, J. L., Taubman, M. A., Ebersole, J. L., & Smith, D. J. (1988) · Journal Of Clinical Periodontology · doi:10.1111/j.1600-051x.1988.tb01577.x · Cited by 256 · see citing works
Gingivitis*
Page, R. C. (1986) · Journal Of Clinical Periodontology · doi:10.1111/j.1600-051x.1986.tb01471.x · Cited by 238 · see citing works
Association Between Cigarette Smoking, Bacterial Pathogens, and Periodontal Status
Stoltenberg, J. L., Osborn, J. B., Pihlstrom, B. L., Herzberg, M. C., Aeppli, D. M., Wolff, L. F., & Fischer, G. E. (1993) · Journal of Periodontology · doi:10.1902/jop.1993.64.12.1225 · Cited by 234 · see citing works
Cigarette Smoking in a Periodontal Practice
Haber, J., & Kent, R. (1992) · Journal of Periodontology · doi:10.1902/jop.1992.63.2.100 · Cited by 225 · see citing works
Association Between Smoking Different Tobacco Products and Periodontal Disease Indexes
Feldman, R. S., Bravacos, J. S., & Rose, C. L. (1983) · Journal of Periodontology · doi:10.1902/jop.1983.54.8.481 · Cited by 222 · see citing works
Co‐twin control study of the relationship between smoking and some periodontal disease factors
Bergström, J., & FLODERUS-MYRHED, B. (1983) · Community Dentistry And Oral Epidemiology · doi:10.1111/j.1600-0528.1983.tb01367.x · Cited by 216 · see citing works
Histopathologic features of the initial and early stages of experimental gingivitis in man
Payne, W., Page, R. C., Ogilvie, A., & Hall, W. B. (1975) · Journal of Periodontal Research · doi:10.1111/j.1600-0765.1975.tb00008.x · Cited by 216 · see citing works
Genetic and Heritable Risk Factors in Periodontal Disease
Michalowicz, B. S. (1994) · Journal of Periodontology · doi:10.1902/jop.1994.65.5s.479 · Cited by 213 · see citing works
Periodontal status in relation to age and tooth type
Papapanou, P. N., Wennström, J. L., & Gröndahl, K. (1988) · Journal Of Clinical Periodontology · doi:10.1111/j.1600-051x.1988.tb01602.x · Cited by 207 · see citing works
Some Microbiological and Histopathological Features of Periodontal Disease in Man
Lindhe, J., Liljenberg, B., & Listgarten, M. A. (1980) · Journal of Periodontology · doi:10.1902/jop.1980.51.5.264 · Cited by 205 · see citing works
Exploratory Case‐Control Analysis of Psychosocial Factors and Adult Periodontitis
Moss, M. E., Beck, J. D., Kaplan, B. H., Offenbacher, S., Weintraub, J. A., Koch, G. G., Genco, R. J., Machtei, E. E., & Tedesco, L. A. (1996) · Journal of Periodontology · doi:10.1902/jop.1996.67.10s.1060 · Cited by 205 · see citing works
Correlated morphometric and biochemical analysis of gingival tissue in early chronic gingivitis in man
Schroeder, H. E., Münzel-Pedrazzoli, S., & Page, R. C. (1973) · Archives of Oral Biology · doi:10.1016/0003-9969(73)90060-5 · Cited by 203 · see citing works
EFFECTS OF SMOKING AND SMOKING CESSATION ON HEALING AFTER MECHANICAL PERIODONTAL THERAPY
Grossi, S. G., Zambon, J. J., Machtei, E. E., Schifferle, R. E., Andreana, S., Genco, R. J., Cummins, D., & Harrap, G. J. (1997) · The Journal of the American Dental Association · doi:10.14219/jada.archive.1997.0259 · Cited by 202 · see citing works
The phenotypic characterization of lymphocyte subpopulations in established human periodontal disease
Seymour, G. J., & Greenspan, J. S. (1979) · Journal of Periodontal Research · doi:10.1111/j.1600-0765.1979.tb00216.x · Cited by 198 · see citing works
Bacteria as Risk Markers for Periodontitis
Wolff, L. F., Dahlén, G., & Aeppli, D. M. (1994) · Journal of Periodontology · doi:10.1902/jop.1994.65.5s.498 · Cited by 195 · see citing works
Conversion of a stable T‐cell lesion to a progressive B‐cell lesion in the pathogenesis of chronic inflammatory periodontal disease: an hypothesis
Seymour, G. J., Powell, R. N., & Davies, W. I. R. (1979) · Journal Of Clinical Periodontology · doi:10.1111/j.1600-051x.1979.tb01930.x · Cited by 177 · see citing works
Longitudinal study of prognostic factors in established periodontitis patients
Machtei, E. E., Dunford, R. G., Hausmann, E., Grossi, S. G., Powell, J. R., Cummins, D., Zambon, J. J., & Genco, R. J. (1997) · Journal Of Clinical Periodontology · doi:10.1111/j.1600-051x.1997.tb00474.x · Cited by 171 · see citing works
Mechanisms of connective tissue matrix destruction in periodontitis
Reynolds, J. J., & Meikle, M. C. (1997) · Periodontology 2000 · doi:10.1111/j.1600-0757.1997.tb00195.x · Cited by 167 · see citing works
Identification and distribution of immunocompetent cells in inflamed gingiva of human chronic periodontitis
Okada, H., 木田, 友., & Yamagami, H. (1983) · Infection and Immunity · doi:10.1128/iai.41.1.365-374.1983 · Cited by 162 · see citing works
Experimental gingivitis in young and elderly individuals
Holm‐Pedersen, P., Agerbæk, N., & Theilade, E. (1975) · Journal Of Clinical Periodontology · doi:10.1111/j.1600-051x.1975.tb01722.x · Cited by 162 · see citing works
Methods of Assessing Risk for Periodontitis and Developing Multifactorial Models
Beck, J. D. (1994) · Journal of Periodontology · doi:10.1902/jop.1994.65.5s.468 · Cited by 160 · see citing works
The Origin of Periodontal Infections
Genco, R. J., Zambon, J. J., & Christersson, L. A. (1988) · Advances in Dental Research · doi:10.1177/08959374880020020901 · Cited by 158 · see citing works
Mechanisms of alveolar bone destruction in periodontitis
Schwartz, Z., Goultschin, J., Dean, D. D., & Boyan, B. D. (1997) · Periodontology 2000 · doi:10.1111/j.1600-0757.1997.tb00196.x · Cited by 152 · see citing works
Occurrence of periopathogens in smoker and non‐smoker patients
Preber, H., Bergström, J., & Linder, L. E. (1992) · Journal Of Clinical Periodontology · doi:10.1111/j.1600-051x.1992.tb01716.x · Cited by 144 · see citing works
Clinical, microbiological and immunological features of subjects with refractory periodontal diseases
Haffajee, A. D., Socransky, S. S., Dzink, J. L., Taubman, M. A., & Ebersole, J. L. (1988) · Journal Of Clinical Periodontology · doi:10.1111/j.1600-051x.1988.tb01017.x · Cited by 144 · see citing works
Periodontitis and Tooth Loss: Comparing Diabetics with the General Population
Oliver, R. C., & Tervonen, T. (1993) · The Journal of the American Dental Association · doi:10.14219/jada.archive.1993.0247 · Cited by 138 · see citing works
Microbial succession in recolonizing deep periodontal pockets after a single course of supra‐ and subgingival debridement
van Winkelhof, A. J., van der Velden, U., & Graaff, J. (1988) · Journal Of Clinical Periodontology · doi:10.1111/j.1600-051x.1988.tb01004.x · Cited by 138 · see citing works
The role of systemic conditions and disorders in periodontal disease
Genco, R. J., & Löe, H. A. (1993) · Periodontology 2000 · doi:10.1111/j.1600-0757.1993.tb00223.x · Cited by 136 · see citing works
Smoking is a major risk factor for periodontitis.
Haber, J. E. (1994) · PubMed · Cited by 133 · see citing works
Genetic Influences in Caries and Periodontal Diseases
Hassell, T. M., & Harris, E. L. (1995) · Critical Reviews in Oral Biology & Medicine · doi:10.1177/10454411950060040401 · Cited by 130 · see citing works
Bacteroides forsythus in adult gingivitis and periodontitis
Lai, C., Listgarten, M. A., Shirakawa, M., & Slots, J. (1987) · Oral Microbiology and Immunology · doi:10.1111/j.1399-302x.1987.tb00299.x · Cited by 114 · see citing works
Risk Indicators for Periodontitis in a Military Treatment Population
Horning, G. M., Hatch, C. L., & Cohen, M. E. (1992) · Journal of Periodontology · doi:10.1902/jop.1992.63.4.297 · Cited by 109 · see citing works
Epidemiology and Prevention of Periodontal Disease in Individuals With Diabetes
Katz, P., Wirthlin, M. R., Szpunar, S. M., Selby, J. V., Sepe, S. J., & Showstack, J. A. (1991) · Diabetes Care · doi:10.2337/diacare.14.5.375 · Cited by 106 · see citing works
Effect of modified Widman flap surgery and systemic tetracycline on the subgingival microbiota of periodontal lesions
Haffajee, A. D., Dzink, J. L., & Socransky, S. S. (1988) · Journal Of Clinical Periodontology · doi:10.1111/j.1600-051x.1988.tb01579.x · Cited by 103 · see citing works
A histological study of experimental gingivitis in man
Zachrisson, B. U. (1968) · Journal of Periodontal Research · doi:10.1111/j.1600-0765.1968.tb01935.x · Cited by 103 · see citing works
Localisation of a gene for prepubertal periodontitis to chromosome 11q14 and identification of a cathepsin C gene mutation
Hart, T. C., Hart, P. S., Michalec, M. D., Zhang, Y., Marazita, M. L., Cooper, M., Yassin, O. M., Nusier, M., & Walker, S. (2000) · Journal of Medical Genetics · doi:10.1136/jmg.37.2.95 · Cited by 102 · see citing works
Periodontal loser sites in untreated adult subjects
Lindhe, J., Okamoto, H., Yoneyama, T., Haffajee, A. D., & Socransky, S. S. (1989) · Journal Of Clinical Periodontology · doi:10.1111/j.1600-051x.1989.tb01038.x · Cited by 102 · see citing works
Oral manifestations of HIV infection in homosexual men and intravenous drug users
Lamster, I. B., Begg, M. D., Mitchell‐Lewis, D. A., Fine, J. B., Grbic, J. T., Todak, G. G., El-Sadr, W. M., Gorman, J. M., Zambon, J. J., & Phelan, J. A. (1994) · Oral Surgery Oral Medicine Oral Pathology · doi:10.1016/0030-4220(94)90140-6 · Cited by 87 · see citing works
Initial gingivitis in dogs
Schroeder, H. E., Beer, M. G., & Attström, R. (1975) · Journal of Periodontal Research · doi:10.1111/j.1600-0765.1975.tb00017.x · Cited by 86 · see citing works
Genetic Risk Factors for Early‐Onset Periodontitis
Hart, T. C. (1996) · Journal of Periodontology · doi:10.1902/jop.1996.67.3s.355 · Cited by 85 · see citing works
Experimental gingivitis in humans
Seymour, G. J., Powell, R. N., Cole, K. L., Aitken, J. F., Brooks, D. A., Beckman, I., Zola, H., Bradley, J., & Burns, G. F. (1983) · Journal of Periodontal Research · doi:10.1111/j.1600-0765.1983.tb00373.x · Cited by 84 · see citing works
Experimental Gingivitis in Humans: A Clinical and Histologic Investigation
Seymour, G. J., Powell, R. N., & Aitken, J. F. (1983) · Journal of Periodontology · doi:10.1902/jop.1983.54.9.522 · Cited by 79 · see citing works
Some microbiological, histopathological and immunohistochemical characteristics of progressive periodontal disease
Liljenberg, B., Lindhe, J., Berglundh, T., Dahlén, G., & Jonsson, R. (1994) · Journal Of Clinical Periodontology · doi:10.1111/j.1600-051x.1994.tb00793.x · Cited by 73 · see citing works
HIV and Periodontal Health
Swango, P. A., Kleinman, D. V., & Konzelman, J. L. (1991) · The Journal of the American Dental Association · doi:10.14219/jada.archive.1991.0212 · Cited by 73 · see citing works
Prevalence of HIV-Associated Periodontitis and Gingivitis in HIV-Infected Patients Attending an AIDS Clinic
Masouredis, C. M., Katz, M. H., Greenspan, D., Herrera, C., Hollander, H., Greenspan, J. S., & Winkler, J. R. (1992) · Journal of acquired immune deficiency syndromes · doi:10.1097/00126334-199205000-00008 · Cited by 65 · see citing works
Acute necrotizing ulcerative gingivitis: risk factors involving host defense mechanisms
Murayama, Y., Kurihara, H., Nagai, A., Dompkowski, D. F., & Dyke, T. E. V. (1994) · Periodontology 2000 · doi:10.1111/j.1600-0757.1994.tb00031.x · Cited by 61 · see citing works
Periodontal Status of HIV‐Seropositive and AIDS Patients
Friedman, R. B., Gunsolley, J. C., Gentry, A. C., Dinius, A., Kaplowitz, L. G., & Settle, J. (1991) · Journal of Periodontology · doi:10.1902/jop.1991.62.10.623 · Cited by 58 · see citing works
Microbiological Testing in the Diagnosis of Periodontal Disease
Listgarten, M. A. (1992) · Journal of Periodontology · doi:10.1902/jop.1992.63.4s.332 · Cited by 51 · see citing works
The Pocket Epithelium: A Light‐ and Electronmicroscopic Study
Müller-Glauser, W., & Schroeder, H. E. (1982) · Journal of Periodontology · doi:10.1902/jop.1982.53.3.133 · Cited by 44 · see citing works
Effect of pre‐experimental maintenance care duration on the development of gingivitis in a partial mouth experimental gingivitis model
van der Weijden, G. A., Timmerman, M. F., Danser, M. M., Nijboer, A., Saxton, C. A., van der Velden, U., & van der Weijden, G. A. (1994) · Journal of Periodontal Research · doi:10.1111/j.1600-0765.1994.tb01209.x · Cited by 44 · see citing works
Stereological observations on long‐term experimental gingivitis in man
Brecx, M. C., Fröhlicher, I., Gehr, P., & Lang, N. P. (1988) · Journal Of Clinical Periodontology · doi:10.1111/j.1600-051x.1988.tb02262.x · Cited by 41 · see citing works
The 'high risk' group in periodontitis
Jenkins, W. M., & Kinane, D. F. (1989) · BDJ · doi:10.1038/sj.bdj.4806955 · Cited by 40 · see citing works
Self-citation
Periodontal Disease in Adolescents: Some Clinical and Microbiologic Correlates of Attachment Loss
Carlos, J. P., Wolfe, M. D., Zambon, J. J., & Kingman, A. (1988) · Journal of Dental Research · doi:10.1177/00220345880670121301 · Cited by 39 · see citing works
Periodontal Disease in Heterosexuals With Acquired Immunodeficiency Syndrome
Klein, R. S., Quart, A. M., & Small, C. B. (1991) · Journal of Periodontology · doi:10.1902/jop.1991.62.8.535 · Cited by 39 · see citing works
Effect of initial treatment of chronic inflammatory periodontal disease on the frequency of peripheral blood T‐lymphocytes specific to periodontopathic bacteria
Mahanonda, R., Seymour, G. J., Powell, L. W., Good, M. F., & Halliday, J. W. (1991) · Oral Microbiology and Immunology · doi:10.1111/j.1399-302x.1991.tb00481.x · Cited by 39 · see citing works
Variability of histologic criteria in clinically healthy human gingiva
Brecx, M. C., Gautschi, M., Gehr, P., & Lang, N. P. (1987) · Journal of Periodontal Research · doi:10.1111/j.1600-0765.1987.tb02057.x · Cited by 35 · see citing works
The nature of the inflammatory infiltrates in childhood gingivitis, juvenile periodontitis and adult periodontitis: immunocytochemical studies using a monoclonal antibody to HLA Dr
Gillett, R., Cruchley, A. T., & Johnson, N. W. (1986) · Journal Of Clinical Periodontology · doi:10.1111/j.1600-051x.1986.tb02223.x · Cited by 32 · see citing works
ELISA and conventional techniques for identification of black‐pigmented Bacteroides isolated from Periodontal pockets
Dzink, J. L., Socransky, S. S., Ebersole, J. L., & Frey, D. E. (1983) · Journal of Periodontal Research · doi:10.1111/j.1600-0765.1983.tb00372.x · Cited by 29 · see citing works
The fine structure of gingivitis in the Bengal
Garant, P. R., & Mulvihill, J. E. (1972) · Journal of Periodontal Research · doi:10.1111/j.1600-0765.1972.tb00641.x · Cited by 28 · see citing works
Cumulative nature of periodontal attachment loss
Machtie, E. E., Dunford, R. G., Grossi, S. G., & Genco, R. J. (1994) · Journal of Periodontal Research · doi:10.1111/j.1600-0765.1994.tb01234.x · Cited by 28 · see citing works

Flagged first, then by citations

Sorted by citations

Periodontal diseases
Kinane, D. F., Stathopoulou, P. G., & Papapanou, P. N. (2017) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2017.38 · Cited by 2,724 · see citing works
Self-citation
The oral microbiome: Role of key organisms and complex networks in oral health and disease
Sedghi, L., DiMassa, V., Harrington, A., Lynch, S. V., & Kapila, Y. L. (2021) · Periodontology 2000 · doi:10.1111/prd.12393 · Cited by 755 · see citing works
Periodontal disease and adverse pregnancy outcomes: a systematic review
Xiong, X., Buekens, P. M., Fraser, W. D., Beck, J. D., & Offenbacher, S. (2006) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.2005.00827.x · Cited by 510 · see citing works
The Role of Matrix Metalloproteinases (MMP-8, MMP-9, MMP-13) in Periodontal and Peri-Implant Pathological Processes
Luchian, I. A., Goriuc, A., Sandu, D., & Covașă, M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23031806 · Cited by 361 · see citing works
Epidemiology and Risk Factors of Periodontal Diseases
Albandar, J. M. (2005) · Dental Clinics of North America · doi:10.1016/j.cden.2005.03.003 · Cited by 359 · see citing works
Periodontal Disease as a Risk Factor for Ischemic Stroke
Grau, A., Becher, H., Ziegler, C. M., Lichy, C., Buggle, F., Kaiser, C., Lutz, R., Bültmann, S., Preusch, M. R., & Dörfer, C. E. (2004) · Stroke · doi:10.1161/01.str.0000110789.20526.9d · Cited by 354 · see citing works
Host‐derived diagnostic markers related to soft tissue destruction and bone degradation in periodontitis
Buduneli, N., & Kinane, D. F. (2011) · Journal Of Clinical Periodontology · doi:10.1111/j.1600-051x.2010.01670.x · Cited by 348 · see citing works
Self-citation
Lethal photosensitisation of oral bacteria and its potential application in the photodynamic therapy of oral infections
Wilson, M. (2004) · Photochemical & Photobiological Sciences · doi:10.1039/b211266c · Cited by 318 · see citing works
Progranulin inhibits LPS-induced macrophage M1 polarization via NF-кB and MAPK pathways
Liu, L., Guo, H., Song, A., Huang, J., Zhang, Y., Jin, S., Li, S., Zhang, L., Yang, C., & Yang, P. (2020) · BMC Immunology · doi:10.1186/s12865-020-00355-y · Cited by 293 · see citing works
Induction of M2 Macrophages Prevents Bone Loss in Murine Periodontitis Models
Zhuang, Z., Yoshizawa-Smith, S., Glowacki, A. J., Maltos, K. L. M., Pacheco, C. M. D. F., Shehabeldin, M., Mulkeen, M., Myers, N. T., Chong, R., Verdelis, K., et al. (2018) · Journal of Dental Research · doi:10.1177/0022034518805984 · Cited by 261 · see citing works
Lipid peroxidation levels, total oxidant status and superoxide dismutase in serum, saliva and gingival crevicular fluid in chronic periodontitis patients before and after periodontal therapy
Wei, D., Zhang, X., Wang, Y., Yang, C., & Chen, G. (2010) · Australian Dental Journal · doi:10.1111/j.1834-7819.2009.01123.x · Cited by 261 · see citing works
Recent advances in the medical applications of hemostatic materials
Guo, Y., Wang, M., Liu, Q., Liu, G., Wang, S., & Li, J. (2022) · Theranostics · doi:10.7150/thno.79639 · Cited by 264 · see citing works
Basement Membranes in Development and Disease
Sekiguchi, R., & Yamada, K. M. (2018) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/bs.ctdb.2018.02.005 · Cited by 243 · see citing works
Progression of chronic periodontitis can be predicted by the levels of Porphyromonas gingivalis and Treponema denticola in subgingival plaque
Byrne, S. J., Dashper, S. G., Darby, I. B., Adams, G. G., Hoffmann, B., & Reynolds, E. C. (2009) · Oral Microbiology and Immunology · doi:10.1111/j.1399-302x.2009.00544.x · Cited by 208 · see citing works
Periodontal Tissue Regeneration Using Fibroblast Growth Factor -2: Randomized Controlled Phase II Clinical Trial
Kitamura, M., Nakashima, K., Kowashi, Y., Fujii, T., Shimauchi, H., Sasano, T., Furuuchi, T., Fukuda, M., Noguchi, T., Shibutani, T., et al. (2008) · PLoS ONE · doi:10.1371/journal.pone.0002611 · Cited by 205 · see citing works
Biomarkers of periodontitis in oral fluids
Rai, B., Kharb, S., Jain, R., & Suresh, A. (2008) · Journal of Oral Science · doi:10.2334/josnusd.50.53 · Cited by 183 · see citing works
Chemokine Function in Periodontal Disease and Oral Cavity Cancer
Sahingur, S. E., & Yeudall, W. A. (2015) · Frontiers in Immunology · doi:10.3389/fimmu.2015.00214 · Cited by 154 · see citing works
Tooth loss and pocket probing depths in compliant periodontally treated patients: a retrospective analysis
König, J., Hc, P., Rühling, A., & Kocher, T. (2002) · Journal Of Clinical Periodontology · doi:10.1034/j.1600-051x.2002.291208.x · Cited by 148 · see citing works
Factors associated with the prevalence of periodontal disease in low-risk pregnant women
Vogt, M., Sallum, A. W., Cecatti, J. G., & Morais, S. S. (2012) · Reproductive Health · doi:10.1186/1742-4755-9-3 · Cited by 135 · see citing works
Periodontitis and gestational diabetes mellitus: a systematic review and meta-analysis of observational studies
Abariga, S. A., & Whitcomb, B. W. (2016) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-016-1145-z · Cited by 137 · see citing works
An Antimicrobial Dental Light Curable Bioadhesive Hydrogel for Treatment of Peri-Implant Diseases
Sani, E. S., Lara, R. P., Aldawood, Z. A., Bassir, S. H., Nguyen, D. H., Kantarcı, A., Intini, G., & Annabi, N. (2019) · Matter · doi:10.1016/j.matt.2019.07.019 · Cited by 135 · see citing works
Defining human mesenchymal and epithelial heterogeneity in response to oral inflammatory disease
Caetano, A. J., Yianni, V., Volponi, A. A., Booth, V., D’Agostino, E. M., & Sharpe, P. T. (2021) · eLife · doi:10.7554/elife.62810 · Cited by 134 · see citing works
Protective Effects of Grape Seed Proanthocyanidins Against Oxidative Stress Induced by Lipopolysaccharides of Periodontopathogens
Houde, V. P., Grenier, D., & Chandad, F. (2006) · Journal of Periodontology · doi:10.1902/jop.2006.050419 · Cited by 128 · see citing works
Association between periodontal disease and stroke
Sfyroeras, G. S., Roussas, N., Saleptsis, V., Argyriou, C., & Giannoukas, A. D. (2012) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2011.10.008 · Cited by 127 · see citing works
Periodontal Disease and Pregnancy Outcomes: State-of-the-Science
Xiong, X., Buekens, P. M., Vastardis, S., & Yu, S. M. (2007) · Obstetrical & Gynecological Survey · doi:10.1097/01.ogx.0000279292.63435.40 · Cited by 120 · see citing works
Gingipains fromPorphyromonas gingivalis— complex domain structures confer diverse functions
Li, N., & Collyer, C. A. (2011) · European Journal of Microbiology and Immunology · doi:10.1556/eujmi.1.2011.1.7 · Cited by 117 · see citing works
The association of gingivitis and periodontitis with ischemic stroke
Dörfer, C. E., Becher, H., Ziegler, C. M., Kaiser, C., Lutz, R., Joerss, D., Lichy, C., Buggle, F., Bültmann, S., Preusch, M. R., et al. (2004) · Journal Of Clinical Periodontology · doi:10.1111/j.1600-051x.2004.00579.x · Cited by 116 · see citing works
Periodontal Disease Is Associated With Gestational Diabetes Mellitus: A Case‐Control Study
Xiong, X., Elkind-Hirsch, K. E., Vastardis, S., Delarosa, R. L., Pridjian, G. C., & Buekens, P. M. (2009) · Journal of Periodontology · doi:10.1902/jop.2009.090250 · Cited by 117 · see citing works
The impact of laser application on periodontal and peri‐implant wound healing
Schwarz, F., Aoki, A., Sculean, A., & Becker, J. (2009) · Periodontology 2000 · doi:10.1111/j.1600-0757.2009.00301.x · Cited by 112 · see citing works
Periodontal and inflammatory bowel diseases: Is there evidence of complex pathogenic interactions?
Lira‐Junior, R., & Figueredo, C. M. (2016) · World Journal of Gastroenterology · doi:10.3748/wjg.v22.i35.7963 · Cited by 111 · see citing works
Maternal periodontal disease, systemic inflammation, and risk for preeclampsia
Ruma, M. S., Boggess, K., MOSS, K. L., Jared, H., Murtha, A. P., Beck, J. D., & Offenbacher, S. (2008) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2007.12.002 · Cited by 110 · see citing works
The Gingipains: Scissors and Glue of the Periodontal Pathogen,Porphyromonas Gingivalis
Fitzpatrick, R. E., Wijeyewickrema, L. C., & Pike, R. N. (2009) · Future Microbiology · doi:10.2217/fmb.09.18 · Cited by 102 · see citing works
Anti-Inflammatory Activity of Curcumin in Macrophages Stimulated by Lipopolysaccharides from Porphyromonas gingivalis
Chen, D., Nie, M., Fan, M., & Bian, Z. (2008) · Pharmacology · doi:10.1159/000161127 · Cited by 109 · see citing works
Fusobacterium nucleatumFacilitates Apoptosis, ROS Generation, and Inflammatory Cytokine Production by Activating AKT/MAPK and NF-κB Signaling Pathways in Human Gingival Fibroblasts
Kang, W., Jia, Z., Tang, D., Zhang, Z., Gao, H., He, K., & Feng, Q. (2019) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2019/1681972 · Cited by 97 · see citing works
Association of periodontal disease with systemic health indices in dogs and the systemic response to treatment of periodontal disease
Rawlinson, J. E., Goldstein, R. E., Reiter, A. M., Attwater, D. Z., & Harvey, C. E. (2011) · Journal of the American Veterinary Medical Association · doi:10.2460/javma.238.5.601 · Cited by 97 · see citing works
Uncovering the molecular networks in periodontitis
Trindade, F., Oppenheim, F. G., Helmerhorst, E. J., Amado, F. M. L., Gomes, P. S., & Vitorino, R. M. P. (2014) · PROTEOMICS - CLINICAL APPLICATIONS · doi:10.1002/prca.201400028 · Cited by 91 · see citing works
Oral bacteria, oral health, and adverse pregnancy outcomes
Xu, B., & Han, Y. W. (2022) · Periodontology 2000 · doi:10.1111/prd.12436 · Cited by 98 · see citing works
Getting the basic rights – the role of water, sanitation and hygiene in maternal and reproductive health: a conceptual framework
Campbell, O. M. R., Beňová, L., Gon, G., Afsana, K., & Cumming, O. (2014) · Tropical Medicine & International Health · doi:10.1111/tmi.12439 · Cited by 93 · see citing works
Accuracy of Artificial Intelligence-Based Photographic Detection of Gingivitis
Chau, R. C. W., Li, G.-H., Tew, I. M., Thu, K. M., McGrath, C. P. J., Lo, A. W.-L., Ling, B. W., Hsung, T.-C., & Lam, W. Y. H. (2023) · International Dental Journal · doi:10.1016/j.identj.2023.03.007 · Cited by 89 · see citing works
The association between periodontitis and obstructive sleep apnea: a preliminary study
Seo, W. H., Cho, E. R., Thomas, R. J., An, S., Ryu, J., Kim, H., & Shin, C. (2012) · Journal of Periodontal Research · doi:10.1111/jre.12032 · Cited by 87 · see citing works
Potential of the Tannerella forsythia S-layer to Delay the Immune Response
Sekot, G., Posch, G., Messner, P., Matĕjka, M., Rausch‐Fan, X., Andrukhov, O., & Schäffer, C. (2010) · Journal of Dental Research · doi:10.1177/0022034510384622 · Cited by 87 · see citing works
Dental Recall. Recall Interval between Routine Dental Examinations
Worthington, H. V., Pitts, N. B., Batchelor, P. A., Clarkson, J., Davenport, C. F., Davies, R. M., Elley, K., Fayle, S. A., Grey, E., Harley, K., et al. (2004) · Research Explorer (The University of Manchester) · Cited by 87 · see citing works
Periodontitis and the Risk for Non‐Fatal Stroke in Korean Adults
Sim, S., Kim, H., Moon, J., Zavras, A. I., Zdanowicz, J. A., Jang, S., Jin, B., Bae, K., Paik, D., & Douglass, C. W. (2008) · Journal of Periodontology · doi:10.1902/jop.2008.080015 · Cited by 86 · see citing works
Obstructive sleep apnoea and periodontitis: a novel association?
Gunaratnam, K., Taylor, B., Curtis, B. H., & Cistulli, P. A. (2009) · Sleep And Breathing · doi:10.1007/s11325-008-0244-0 · Cited by 86 · see citing works
Autologous platelet concentrates for treating periodontal infrabony defects
FABBRO, M. D., Karanxha, L., Panda, S., Bucchi, C., Doraiswamy, J. N., Malaiappan, S., Ramamoorthi, S., Varghese, S. S., & Taschieri, S. (2018) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd011423.pub2 · Cited by 85 · see citing works
Association Between Maternal Periodontitis and an Increased Risk of Preeclampsia
Cota, L. O. M., Guimarães, A. N., Costa, J. E., Lorentz, T. C. M., & Costa, F. O. (2006) · Journal of Periodontology · doi:10.1902/jop.2006.060061 · Cited by 84 · see citing works
Immunologic burden links periodontitis to acute coronary syndrome
Liljestrand, J. M., Paju, S., Pietiäinen, M., Buhlin, K., Persson, G. R., Nieminen, M. S., Sinisalo, J. P., Mäntylä, P., & Pussinen, P. J. (2017) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2017.12.007 · Cited by 82 · see citing works
Microbial and metabolomic analysis of gingival crevicular fluid in general chronic periodontitis patients: lessons for a predictive, preventive, and personalized medical approach
Pei, J., Li, F. R., Xie, Y., Liu, J., Tian, Y., & Feng, X. (2020) · The EPMA Journal · doi:10.1007/s13167-020-00202-5 · Cited by 80 · see citing works
Influence of an Erbium, Chromium‐Doped Yttrium, Scandium, Gallium, and Garnet (Er,Cr:YSGG) Laser on the Reestablishment of the Biocompatibility of Contaminated Titanium Implant Surfaces
Schwarz, F., Nuesry, E., Bieling, K., Herten, M., & Becker, J. (2006) · Journal of Periodontology · doi:10.1902/jop.2006.050456 · Cited by 80 · see citing works
Hyperglycemia induced and intrinsic alterations in type 2 diabetes‐derived osteoclast function
Catalfamo, D., Britten, T., Storch, D., Calderon, N., Sorenson, H., & Wallet, S. M. (2012) · Oral Diseases · doi:10.1111/odi.12002 · Cited by 79 · see citing works
Upregulation of heme oxygenase-1 via PI3K/Akt and Nrf-2 signaling pathways mediates the anti-inflammatory activity of Schisandrin in Porphyromonas gingivalis LPS-stimulated macrophages
Park, S. Y., Park, D. J., Kim, Y. H., Kim, Y., Kim, S. G., Shon, K.-J., Choi, Y. W., & Lee, S.-J. (2011) · Immunology Letters · doi:10.1016/j.imlet.2011.05.007 · Cited by 79 · see citing works
Periodontal disease and gestational diabetes mellitus
Xiong, X., Buekens, P. M., Vastardis, S., & Pridjian, G. C. (2006) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2006.06.035 · Cited by 78 · see citing works
Salivary concentration of the antimicrobial peptide LL-37 in children
Davidopoulou, S., Diza, E., Menexes, G. C., & Kalfas, S. (2012) · Archives of Oral Biology · doi:10.1016/j.archoralbio.2012.01.008 · Cited by 76 · see citing works
Both 25-Hydroxyvitamin-D3 and 1,25-Dihydroxyvitamin-D3 Reduces Inflammatory Response in Human Periodontal Ligament Cells
Andrukhov, O., Andrukhova, O., Hulan, U., Tang, Y., Bantleon, H., & Rausch‐Fan, X. (2014) · PLoS ONE · doi:10.1371/journal.pone.0090301 · Cited by 75 · see citing works
Thermo‐Reversible Green Tea Catechin Gel for Local Application in Chronic Periodontitis: A 4‐Week Clinical Trial
Chava, V. K., & Vedula, B. D. (2012) · Journal of Periodontology · doi:10.1902/jop.2012.120425 · Cited by 74 · see citing works
Phase I/II Trial of Autologous Bone Marrow Stem Cell Transplantation with a Three‐Dimensional Woven‐Fabric Scaffold for Periodontitis
Baba, S., Yamada, Y., Komuro, A., Yotsui, Y., Umeda, M., Shimuzutani, K., & Nakamura, S. (2016) · Stem Cells International · doi:10.1155/2016/6205910 · Cited by 74 · see citing works
Anti-inflammatory effects of isorhamnetin on LPS-stimulated human gingival fibroblasts by activating Nrf2 signaling pathway
Qi, F., Sun, J.-H., Yan, J.-Q., Li, C.-M., & Xue-chao, L. (2018) · Microbial Pathogenesis · doi:10.1016/j.micpath.2018.04.049 · Cited by 72 · see citing works
Oxidative stress induced pyroptosis leads to osteogenic dysfunction of MG63 cells
Liu, S., Du, J., Li, D., Yang, P., Kou, Y., Li, C., Zhou, Q., Lu, Y., Hasegawa, T., & Li, M. (2020) · Journal of Molecular Histology · doi:10.1007/s10735-020-09874-9 · Cited by 71 · see citing works
Association between periodontal disease and gestational diabetes mellitus—A prospective cohort study
Kumar, A., Sharma, D., Verma, M., Lamba, A. K., Gupta, M. M., Sharma, S. B., & Vanamail, P. (2018) · Journal Of Clinical Periodontology · doi:10.1111/jcpe.12902 · Cited by 69 · see citing works
Silver Nanoparticles as Chlorhexidine and Metronidazole Drug Delivery Platforms: Their Potential Use in Treating Periodontitis
Steckiewicz, K. P., Cieciórski, P., Barcińska, E., Jaśkiewicz, M., Narajczyk, M., Bauer, M., Kamysz, W., Megiel, E., & Inkielewicz‐Stępniak, I. (2022) · International Journal of Nanomedicine · doi:10.2147/ijn.s339046 · Cited by 69 · see citing works
Evaluation of C-Reactive Protein and Fibrinogen in Patients with Chronic and Aggressive Periodontitis: A Clinico-Biochemical Study
Chandy, S. (2017) · JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH · doi:10.7860/jcdr/2017/23100.9552 · Cited by 69 · see citing works
Association of matrix metalloproteinase (MMP)-1, 3, 9, interleukin (IL)-2, 8 and cyclooxygenase (COX)-2 gene polymorphisms with chronic periodontitis in a Chinese population
Li, G., Yue, Y., Tian, Y., Li, J., Wang, M., Liang, H., Liao, P., Loo, W. T. Y., Cheung, M., & Chow, L. W. (2012) · Cytokine · doi:10.1016/j.cyto.2012.06.239 · Cited by 68 · see citing works
Porphyromonas gingivalis Outer Membrane Vesicles Promote Apoptosis via msRNA-Regulated DNA Methylation in Periodontitis
Fan, R., Zhou, Y., Chen, X., Zhong, X., He, F., Peng, W., Li, L., Wang, X., & Xu, Y. (2023) · Microbiology Spectrum · doi:10.1128/spectrum.03288-22 · Cited by 70 · see citing works
Characterization of Chitosan‐Gallic Acid Graft Copolymer for Periodontal Dressing Hydrogel Application
Feng, M., Zeng, X., Lin, Q., Wang, Y., Wei, H., Yang, S., Wang, G., Chen, X., Guo, M., Yang, X., et al. (2023) · Advanced Healthcare Materials · doi:10.1002/adhm.202302877 · Cited by 66 · see citing works
Full‐mouth profile of active MMP‐8 in periodontitis patients
Kraft‐Neumärker, M., Lorenz, K., Koch, R., Hoffmann, T. K., Mäntylä, P., Sorsa, T. A., & Netuschil, L. (2011) · Journal of Periodontal Research · doi:10.1111/j.1600-0765.2011.01416.x · Cited by 66 · see citing works
Multi-omics Analysis of Periodontal Pocket Microbial Communities Pre- and Posttreatment
Califf, K. J., Schwarzberg-Lipson, K., Garg, N., Gibbons, S. M., Caporaso, J. G., Slots, J., Cohen, C., Dorrestein, P. C., & Kelley, S. T. (2017) · mSystems · doi:10.1128/msystems.00016-17 · Cited by 66 · see citing works
Porphyromonas gingivalis-Derived Lipopolysaccharide Combines Hypoxia to Induce Caspase-1 Activation in Periodontitis
Cheng, R., Liu, W., Zhang, R., Feng, Y., Bhowmick, N. A., & Hu, T. (2017) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2017.00474 · Cited by 65 · see citing works
Association Between Periodontitis and Hemorrhagic Stroke Among Koreans: A Case‐Control Study
Kim, H., Sim, S., Moon, J., Hong, Y., & Han, D. (2010) · Journal of Periodontology · doi:10.1902/jop.2010.090614 · Cited by 64 · see citing works
Effects of Herbal Mouthwashes on Plaque and Inflammation Control for Patients with Gingivitis: A Systematic Review and Meta‐Analysis of Randomised Controlled Trials
Cai, H., Chen, J., Perera, N. K. P., & Liang, X. (2020) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2020/2829854 · Cited by 63 · see citing works
Proxy-Bridged Image Reconstruction Network for Anomaly Detection in Medical Images
Zhou, K., Li, J., Luo, W., Li, Z., Yang, J., Fu, H., Cheng, J., Liu, J., & Gao, S. (2021) · IEEE Transactions on Medical Imaging · doi:10.1109/tmi.2021.3118223 · Cited by 61 · see citing works
Mesenchymal stem cell-derived apoptotic bodies alleviate alveolar bone destruction by regulating osteoclast differentiation and function
Li, X., Jiang, Y., Liu, X., Fu, J., Du, J., Luo, Z., Xu, J., BHAWAL, U. K., Liu, Y. F., & Guo, L. (2023) · International Journal of Oral Science · doi:10.1038/s41368-023-00255-y · Cited by 60 · see citing works
Association Between Periodontitis and Gestational Diabetes Mellitus: Systematic Review and Meta‐Analysis
Lima, R. P. E., Cyrino, R. M., Dutra, B. D. C., da Silveira, J. O., Martins, C. C., Cota, L. O. M., & Costa, F. O. (2015) · Journal of Periodontology · doi:10.1902/jop.2015.150311 · Cited by 57 · see citing works
The Oral Microbiome and Inflammation in Mild Cognitive Impairment
Yang, I., Arthur, R. A., Zhao, L., Clark, J., Hu, Y., Corwin, E. J., & Lah, J. (2021) · Experimental Gerontology · doi:10.1016/j.exger.2021.111273 · Cited by 56 · see citing works
Clinical Use of Paraprobiotics for Pregnant Women with Periodontitis: Randomized Clinical Trial
Butera, A., Pascadopoli, M., Nardi, M. G., Ogliari, C., Chiesa, A., Preda, C., Perego, G., & Scribante, A. (2024) · Dentistry Journal · doi:10.3390/dj12040116 · Cited by 56 · see citing works
Heme oxygenase-1 signals are involved in preferential inhibition of pro-inflammatory cytokine release by surfactin in cells activated with Porphyromonas gingivalis lipopolysaccharide
Park, S. Y., Kim, Y. H., Kim, E., Ryu, E. Y., & Lee, S.-J. (2010) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2010.09.007 · Cited by 55 · see citing works
Is the prevalence of periodontitis in the USA in decline?
Cobb, C. M., Williams, K. B., & Gerkovitch, M. M. (2009) · Periodontology 2000 · doi:10.1111/j.1600-0757.2008.00284.x · Cited by 55 · see citing works
The role of extracellular vesicles in periodontitis: pathogenesis, diagnosis, and therapy
Cai, R., Wang, L., Zhang, W., Liu, B., Wu, Y., Pang, J., & Ma, C. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1151322 · Cited by 55 · see citing works
Changes in inflammatory mediators in gingival crevicular fluid following periodontal disease treatment in pregnancy: relationship to adverse pregnancy outcome
Penova‐Veselinovic, B., Keelan, J. A., Wang, C. A., Newnham, J. P., & Pennell, C. E. (2015) · Journal of Reproductive Immunology · doi:10.1016/j.jri.2015.05.002 · Cited by 54 · see citing works
Dental manifestations of pregnancy
Pirie, M., Cooke, I., Linden, G. J., & Irwin, C. (2007) · The Obstetrician & Gynaecologist · doi:10.1576/toag.9.1.021.27292 · Cited by 53 · see citing works
Antibacterial activity of a bacteriocin from Lactobacillus paracasei HL32 against Porphyromonas gingivalis
Pangsomboon, K., Kaewnopparat, S., Pitakpornpreecha, T., & Srichana, T. (2006) · Archives of Oral Biology · doi:10.1016/j.archoralbio.2006.03.008 · Cited by 54 · see citing works
Nanodiamond as efficient peroxidase mimic against periodontal bacterial infection
Fang, J., Wang, H., Bao, X., Ni, Y., Teng, Y., Liu, J., Sun, X., Sun, Y. L., Li, H., & Zhou, Y. (2020) · Carbon · doi:10.1016/j.carbon.2020.07.055 · Cited by 53 · see citing works
Periodontal status correlates with anti‐citrullinated protein antibodies in first‐degree relatives of individuals with rheumatoid arthritis
Loutan, L., Alpizar-Rodriguez, D., Courvoisier, D. S., Finckh, A., Mombelli, A., & Giannopoulou, C. (2019) · Journal Of Clinical Periodontology · doi:10.1111/jcpe.13117 · Cited by 53 · see citing works
Immunohistochemical and Stereologic Analysis of NF-κB Activation in Chronic Periodontitis.
Arabacı, T., Çiçek, Y., Çanakçı, V., Çanakçı, C. F., Özgöz, M., Albayrak, M., & Keleş, O. N. (2010) · PubMed Central · Cited by 51 · see citing works
Effect of periodontal treatment on serum C-reactive protein level in obese and normal-weight women affected with chronic periodontitis.
Al‐Zahrani, M. S., & Al-Ghamdi, H. S. (2012) · Saudi Medical Journal · doi:10.15537/1658-3175.5512 · Cited by 50 · see citing works
Isolation, Processing and Analysis of Murine Gingival Cells
Mizraji, G., Segev, H., Wilensky, A., & Hovav, A. (2013) · Journal of Visualized Experiments · doi:10.3791/50388 · Cited by 50 · see citing works
Schisandra chinensis α-iso-cubebenol induces heme oxygenase-1 expression through PI3K/Akt and Nrf2 signaling and has anti-inflammatory activity in Porphyromonas gingivalis lipopolysaccharide-stimulated macrophages
Park, S. Y., Park, D. J., Kim, Y. H., Kim, Y., Choi, Y. W., & Lee, S.-J. (2011) · International Immunopharmacology · doi:10.1016/j.intimp.2011.07.023 · Cited by 50 · see citing works
Risk assessment for clinical attachment loss of periodontal tissue in Korean adults
Rheu, G.-B., Ji, S., Ryu, J., Lee, J.-B., Shin, C., Lee, J. Y., Huh, J., & Shin, S. (2011) · The Journal of Advanced Prosthodontics · doi:10.4047/jap.2011.3.1.25 · Cited by 50 · see citing works
The Effect of ABO Blood Types on Periodontal Status
Demir, T., Tezel, A., Orbak, R., Eltas, A., Kara, C., & Kavrut, F. (2007) · European Journal of Dentistry · doi:10.1055/s-0039-1698329 · Cited by 50 · see citing works
Effectiveness of Herbal Medicines with Anti-Inflammatory, Antimicrobial, and Antioxidant Properties in Improving Oral Health and Treating Gingivitis and Periodontitis: A Systematic Review
Malcangi, G., Inchingolo, A., Casamassima, L., Trilli, I., Ferrante, L., Inchingolo, F., Palermo, A., Inchingolo, A., & Dipalma, G. (2025) · Nutrients · doi:10.3390/nu17050762 · Cited by 55 · see citing works
Systemic inflammatory burden and local inflammation in periodontitis: What is the link between inflammatory biomarkers in serum and gingival crevicular fluid?
Zekeridou, A., Mombelli, A., Cancela, J., Courvoisier, D., & Giannopoulou, C. (2019) · Clinical and Experimental Dental Research · doi:10.1002/cre2.162 · Cited by 49 · see citing works
Response of human periodontal ligament stem cells to IFN-γ and TLR-agonists
Andrukhov, O., Hong, J. S.-A., Andrukhova, O., Blufstein, A., Moritz, A., & Rausch‐Fan, X. (2017) · Scientific Reports · doi:10.1038/s41598-017-12480-7 · Cited by 47 · see citing works
Anti-infective therapy with an Er:YAG laser: influence on peri-implant healing
Sculean, A., Schwarz, F., & Becker, J. (2005) · Expert Review of Medical Devices · doi:10.1586/17434440.2.3.267 · Cited by 46 · see citing works
Pattern of distribution of Prevotella species/phylotypes associated with healthy gingiva and periodontal disease
Nadkarni, M. A., Browne, G. V., Chhour, K.-L., Byun, R., Nguyen, K.-A. T., Chapple, C. C., Jacques, N. A., & Hunter, N. (2012) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-012-1651-5 · Cited by 46 · see citing works
Causal theory and the etiology of periodontal diseases.
Heaton, B., & Dietrich, T. (2012) · Periodontology 2000 · doi:10.1111/j.1600-0757.2011.00414.x · Cited by 47 · see citing works
Fibre guiding scaffolds for periodontal tissue engineering
Staples, R., Ivanovski, S., & Vaquette, C. (2020) · Journal of Periodontal Research · doi:10.1111/jre.12729 · Cited by 45 · see citing works
An in vitro study of plasticized poly(lactic‐ co ‐glycolic acid) films as possible guided tissue regeneration membranes: Material properties and drug release kinetics
Owen, G., Jackson, J. K., Chehroudi, B., Brunette, D. M., & Burt, H. M. (2010) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.32865 · Cited by 44 · see citing works
Combining Host Modulation and Topical Antimicrobial Therapy in the Management of Moderate to Severe Periodontitis: A Randomized Multicenter Trial
Novak, M. J., Dawson, D. R., Magnusson, I., Karpinia, K., Polson, A. M., Polson, A. P., RYAN, M. E., Ciancio, S. G., Drisko, C. H., Kinane, D. F., et al. (2007) · Journal of Periodontology · doi:10.1902/jop.2008.070237 · Cited by 44 · see citing works
Self-citation
Anti-plaque and anti-gingivitis effect of Papain, Bromelain, Miswak and Neem containing dentifrice: A randomized controlled trial
Tadikonda, A. N., Pentapati, K. C., Urala, A. S., & Acharya, S. (2017) · Journal of Clinical and Experimental Dentistry · doi:10.4317/jced.53593 · Cited by 43 · see citing works
Periodontal Disease Early in Pregnancy Is Associated With Maternal Systemic Inflammation Among African American Women
Horton, A., Boggess, K., MOSS, K. L., Jared, H., Beck, J. D., & Offenbacher, S. (2008) · Journal of Periodontology · doi:10.1902/jop.2008.070655 · Cited by 43 · see citing works
A pilot study of active enzyme levels in gingival crevicular fluid of patients with chronic periodontal disease
Gul, S. S., Douglas, C. W. I., Griffiths, G. S., & Rawlinson, Ā. (2016) · Journal Of Clinical Periodontology · doi:10.1111/jcpe.12568 · Cited by 41 · see citing works

The pathogenesis of human periodontitis: an introduction.
Page, R., & Kornman, K. (1997) · Periodontology 2000 · doi:10.1111/j.1600-0757.1997.tb00189.x · Cited by 1,104 · see citing works
Influence of risk factors on the pathogenesis of periodontitis
Salvi, G. E., Lawrence, H. P., Offenbacher, S., & Beck, J. D. (1997) · Periodontology 2000 · doi:10.1111/j.1600-0757.1997.tb00197.x · Cited by 279 · see citing works
Genetic factors in the pathogenesis of periodontitis
Hart, T. C., & Kornman, K. S. (1997) · Periodontology 2000 · doi:10.1111/j.1600-0757.1997.tb00198.x · Cited by 227 · see citing works
Microbiology of periodontal diseases: introduction
Haffajee, A. D., & Socransky, S. S. (2005) · Periodontology 2000 · doi:10.1111/j.1600-0757.2005.00112.x · Cited by 140 · see citing works
Understanding the etiology of periodontitis: an overview of periodontal risk factors
Nunn, M. E. (2003) · Periodontology 2000 · doi:10.1046/j.0906-6713.2002.03202.x · Cited by 292 · see citing works

Authors: Kinane, D. F.
Affiliations: University of Glasgow (GB)
Corresponding author: Kinane, Denis F.
ORCID: Kinane, Denis F.
Venue: Periodontology 2000
Publisher: Wiley
Published: 2001-02
Volume: 25
Issue: 1
Pages: 8-20
ISSN: 0906-6713 (ISSN-L)
1600-0757
DOI: 10.1034/j.1600-0757.2001.22250102.x
OpenAlex: W2079692416
Cited by: 553
References: 90
Citations by year: 2026: 21 · 2025: 41 · 2024: 43 · 2023: 37 · 2022: 44 · 2021: 40 · 2020: 28 · 2019: 33 · 2018: 20 · 2017: 20 · 2016: 29 · 2015: 19 · 2014: 24 · 2013: 15 · 2012: 34
FWCI: 0.69
Type: journal article
Language: en
Open access: closed
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor, 346 d)
Locations: Periodontology 2000 (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Dentistry › Periodontics › Oral microbiology and periodontitis research
Health Sciences › Medicine › Urology › Periodontal Regeneration and Treatments
Health Sciences › Dentistry › General Dentistry › Dental Research and COVID-19
Keywords: periodontal disease, causality, pathogenesis, periodontitis, periodontal pathogens
MeSH terms: Chronic Disease, Dental Plaque, Disease, Disease Susceptibility, Gingivitis, Humans, Periodontal Diseases, Risk Factors, Smoking, Disease Progression

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Causation and pathogenesis of periodontal disease

Integrity signals

Claims the paper makes

Claims other papers make about this one

Cites

Cited by

Related

Record

About these checks