Individual Behavioral Profiles and Predictors of Treatment Effectiveness for Children With Autism.
Abstract
Differential responsiveness to intervention programs suggests the inadequacy of a single treatment approach for all children with autism. One method for reducing outcome variability is to identify participant characteristics associated with different outcomes for a specific intervention. In this investigation, an analysis of archival data yielded 2 distinct behavioral profiles for responders and nonresponders to a widely used behavioral intervention, pivotal response training (PRT). In a prospective study, these profiles were used to select 6 children (3 predicted responders and 3 predicted nonresponders) who received PRT. Children with pretreatment responder profiles evidenced positive changes on a range of outcome variables. Children with pretreatment nonresponder profiles did not exhibit improvements. These results offer promise for the development of individualized treatment protocols for children with autism.
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Individual differences in reward motivation may predict differences in response to treatment in ASD.
“and there is some evidence that individual differences in reward motivation may predict differences in response to treatment [580].”
From Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings (2012) · cites this paper as [580]
Reward-based interventions are not successful for all children with ASD.
“Even with this scaffolding, however, reward-based interventions are not successful for all children with ASD [579-582]”
From Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings (2012) · cites this paper as [580]
Young children with ASD who display stronger social approach ('wanting') and fewer avoidance behaviors at treatment onset are more responsive to early intensive behavioral interventions than are passive and avoidant children.
“Young children with ASD who display stronger social approach (‘wanting’) and fewer avoidance behaviors at treatment onset are more responsive to early intensive behavioral interventions than are passive and avoidant children [198-202].”
From Social “wanting” dysfunction in autism: neurobiological underpinnings and treatment implications (2012) · cites this paper as [202]
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- Authors
- Sherer, M. R., & Schreibman, L.
- Affiliations
- University of California San Diego (US)
- Venue
- Journal of Consulting and Clinical Psychology
- Published
- 2005
- Volume
- 73
- Issue
- 3
- Pages
- 525-538
- ISSN
- 0022-006X (ISSN-L)
- 1939-2117
- OpenAlex
- W2096797937
- Cited by
- 230
- References
- 5
- Citations by year
- 2026: 4 · 2025: 2 · 2024: 4 · 2023: 3 · 2022: 7 · 2021: 9 · 2020: 12 · 2019: 20 · 2018: 13 · 2017: 10 · 2016: 9 · 2015: 11 · 2014: 21 · 2013: 15 · 2012: 18
- FWCI
- 4.61
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Consulting and Clinical Psychology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Mental Health (MH 39434)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Social Sciences › Psychology › Developmental and Educational Psychology › Behavioral and Psychological Studies
- Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
- Keywords
- autism spectrum disorder, pivotal response training, treatment response, behavioral profiles, predictors of treatment outcome, personalized treatment, children with autism, behavioral interventions, outcome variability
- MeSH terms
- Autistic Disorder, Mental Disorders, Child, Child, Preschool, Female, Humans, Male, Psychotherapy, Treatment Outcome
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