A Pivotal Response Treatment Package for Children With Autism Spectrum Disorder: An RCT

Gengoux, Grace W.; Abrams, Daniel A.; Schuck, Rachel; Millan, Maria Estefania; Libove, Robin; Ardel, Christina M.; Phillips, Jennifer M.; Fox, Melanie; Frazier, Thomas W.; Hardan, Antonio Y.

doi:10.1542/peds.2019-0178

Cited by 121Autism Spectrum Disorder ResearchBehavioral and Psychological StudiesChild Nutrition and Feeding Issues

A Pivotal Response Treatment Package for Children With Autism Spectrum Disorder: An RCT

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Gengoux, Grace W., Abrams, Daniel A., Schuck, Rachel, Millan, Maria Estefania, Libove, Robin, Ardel, Christina M., Phillips, Jennifer M., Fox, Melanie +2 more·2019·Pediatrics

DOI 10.1542/peds.2019-0178PMC PMC6856784

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Abstract

OBJECTIVES: Our aim was to conduct a randomized controlled trial to evaluate a pivotal response treatment package (PRT-P) consisting of parent training and clinician-delivered in-home intervention on the communication skills of children with autism spectrum disorder. METHODS: Forty-eight children with autism spectrum disorder and significant language delay between 2 and 5 years old were randomly assigned to PRT-P (n = 24) or the delayed treatment group (n = 24) for 24 weeks. The effect of treatment on child communication skills was assessed via behavioral coding of parent-child interactions, standardized parent-report measures, and blinded clinician ratings. RESULTS: Analysis of child utterances during the structured laboratory observation revealed that, compared with the delayed treatment group, children in PRT-P demonstrated greater improvement in frequency of functional utterances (F1,41 = 6.07; P = .026; d = 0.61). The majority of parents in the PRT-P group (91%) were able to implement pivotal response treatment (PRT) with fidelity within 24 weeks. Children receiving PRT-P also demonstrated greater improvement on the Brief Observation of Social Communication Change, on the Clinical Global Impressions Improvement subscale, and in number of words used on a parent-report questionnaire. CONCLUSIONS: This is the first 24-week randomized controlled trial in which community treatment is compared with the combination of parent training and clinician-delivered PRT. PRT-P was effective for improving child social communication skills and for teaching parents to implement PRT. Additional research will be needed to understand the optimal combination of treatment settings, intensity, and duration, and to identify child and parent characteristics associated with treatment response.

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Brief parent training in pivotal response treatment for preschoolers with autism
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Authors: Gengoux, G. W., Abrams, D. A., Schuck, R., Millan, M. E., Libove, R., Ardel, C. M., Phillips, J. M., Fox, M., Frazier, T. W., & Hardan, A. Y.
Affiliations: Stanford Medicine (US)
Palo Alto University (US)
Autism Speaks (US)
ORCID: Gengoux, Grace W.
Abrams, Daniel A.
Schuck, Rachel
Phillips, Jennifer M.
Frazier, Thomas W.
Hardan, Antonio Y.
Venue: Pediatrics
Publisher: American Academy of Pediatrics (AAP)
Published: 2019-09-01
Volume: 144
Issue: 3
ISSN: 0031-4005 (ISSN-L)
1098-4275
DOI: 10.1542/peds.2019-0178
PMC: PMC6856784
OpenAlex: W2964763838
Cited by: 121
References: 38
Citations by year: 2026: 16 · 2025: 24 · 2024: 19 · 2023: 14 · 2022: 17 · 2021: 17 · 2020: 11 · 2019: 3
FWCI: 6.98
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: PEDIATRICS (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (UL1TR001085, UL1TR003142)
National Institute of Mental Health (K01MH102428)
National Center for Advancing Translational Sciences
Topics: Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
Social Sciences › Psychology › Developmental and Educational Psychology › Behavioral and Psychological Studies
Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
Keywords: Pivotal Response Treatment, autism spectrum disorder, parent training, home-based intervention, social communication skills, language delay, early childhood intervention, parent-child interaction, intervention fidelity, community-based treatment
MeSH terms: Autism Spectrum Disorder, Behavior Therapy, Child, Preschool, Combined Modality Therapy, Communication, Female, Home Care Services, Humans, Male, Parent-Child Relations, Parents

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A Pivotal Response Treatment Package for Children With Autism Spectrum Disorder: An RCT

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