The DOI matches its Crossref record; 101 of the 102 references it cites were found in a registry or an index.
Reducing relapse and recurrence in unipolar depression: a comparative meta-analysis of cognitive-behavioral therapy’s effects
Open accessAbstract
Relapse and recurrence following response to acute-phase treatment for major depressive disorder (MDD) are prevalent and costly. In a meta-analysis of 28 studies including 1,880 adults, the authors reviewed the world's published literature on cognitive-behavioral therapies (CT) aimed at preventing relapse-recurrence in MDD. Results indicate that after discontinuation of acute-phase treatment, many responders to CT relapse-recur (29% within 1 year and 54% within 2 years). These rates appear comparable to those associated with other depression-specific psychotherapies but lower than those associated with pharmacotherapy. Among acute-phase treatment responders, continuation-phase CT reduced relapse-recurrence compared with assessment only at the end of continuation treatment (21% reduction) and at follow-up (29% reduction). Continuation-phase CT also reduced relapse-recurrence compared with other active continuation treatments at the end of continuation treatment (12% reduction) and at follow-up (14% reduction). The authors discuss implications for research and patient care and suggest directions, with methodological refinements, for future studies.
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In the citing paper
“However, numerous high-quality studies show that treatment effects wane and that the risk of relapse ranges from 29% to 51% in the first year after treatment completion 2-4 .”
From ChatGPT: five priorities for research (2023) · cites this paper as [4]
In the citing paper
“Meta-analyses focusing on psychological relapse prevention interventions for depressive disorders indicate that these interventions are effective in preventing relapse, with reductions of 22–50% in relapse [18, 44–48].”
From Psychological interventions to prevent relapse in anxiety and depression: A systematic review and meta-analysis (2022) · cites this paper as [47]
In the citing paper
“approximately 40%–50% of patients relapse within 1–2 years of receiving treatment (8, 9).”
From A narrative review of digital biomarkers in the management of major depressive disorder and treatment-resistant forms (2023) · cites this paper as [9]
In the citing paper
“Significantly, fewer participants receiving ICBT experienced relapse compared with those in the control group (10.5 compared with 37.8%), which is in line with previous face-to-face studies [30].”
From Internet-based psychological treatments for depression (2012) · cites this paper as [30]
In the citing paper
“A number of psychological interventions have been developed that can be used to target such cognitive change in remitted depressed individuals, most notably cognitive-behavior therapy (CBT; Vittengl, Clark, Dunn, & Jarrett, 2007) and mindfulness-based cognitive therapy (MBCT; Segal, Williams, & Teasdale, 2012).”
From Beneficial effects of training in self-distancing and perspective broadening for people with a history of recurrent depression (2017) · cites this paper as Vittengl, Clark, Dunn, & Jarrett, 2007
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ChatGPT: five priorities for research
van Dis, E. A. M., Bollen, J., Zuidema, W., van Rooij, R., & Bockting, C. L. (2023) · Nature · doi:10.1038/d41586-023-00288-7 · Cited by 1,842
PRACTICE GUIDELINE FOR THE Treatment of Patients With Major Depressive Disorder
Gelenberg, A. J., Freeman, P. B., Markowitz, J. C., Rosenbaum, J. F., Thase, M. E., Trivedi, M. H., & Rhoads, R. S. (2010) · Cited by 1,372
Cuijpers, P., Berking, M., Andersson, G., Quigley, L., Kleiboer, A., & Dobson, K. S. (2013) · The Canadian Journal of Psychiatry · doi:10.1177/070674371305800702 · Cited by 1,066
Mental Health Smartphone Apps: Review and Evidence-Based Recommendations for Future Developments
Bakker, D., Kazantzis, N., Rickwood, D., & Rickard, N. (2016) · JMIR Mental Health · doi:10.2196/mental.4984 · Cited by 886
“Furthermore, CBT-based support can help prevent relapse [101], expand an individual’s coping skills repertoire [102], and assist individuals experiencing psychological distress to avoid developing a clinical disorder [103].”
Lane, R. D., Ryan, L., Nadel, L., & Greenberg, L. S. (2014) · Behavioral and Brain Sciences · doi:10.1017/s0140525x14000041 · Cited by 611
Metadata
- Authors
- Vittengl, J. R., Clark, L. A., Dunn, T. W., & Jarrett, R. B.
- Affiliations
- Truman State University (US)
- University of Iowa (US)
- The University of Texas Southwestern Medical Center (US)
- Venue
- Journal of Consulting and Clinical Psychology
- Published
- 2007
- Volume
- 75
- Issue
- 3
- Pages
- 475-488
- ISSN
- 0022-006X (ISSN-L)
- 1939-2117
- PMC
- PMC2630051
- OpenAlex
- W1981386178
- Cited by
- 551
- References
- 102
- Citations by year
- 2026: 11 · 2025: 15 · 2024: 24 · 2023: 19 · 2022: 22 · 2021: 30 · 2020: 34 · 2019: 42 · 2018: 35 · 2017: 32 · 2016: 36 · 2015: 36 · 2014: 38 · 2013: 29 · 2012: 37
- FWCI
- 4.36
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Consulting and Clinical Psychology (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Mental Health (MH-58397; MH-01571)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
- Keywords
- major depressive disorder, relapse prevention, recurrence prevention, cognitive behavioral therapy, acute phase treatment, psychotherapy versus pharmacotherapy, treatment discontinuation
- MeSH terms
- Depressive Disorder, Humans, Recurrence, Cognitive Behavioral Therapy
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