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Cited by 943Stress and Burnout ResearchOccupational Health and BurnoutWorkplace Health and Well-being

The DOI matches its Crossref record; 361 of the 370 references it cites were found in a registry or an index.

Burnout and risk of cardiovascular disease: Evidence, possible causal paths, and promising research directions.

Melamed, Samuel, Shirom, Arie, Toker, Sharon, Berliner, Shlomo, Shapira, Itzhak·2006·Psychological Bulletin
DOI 10.1037/0033-2909.132.3.327
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Abstract

Burnout is characterized by emotional exhaustion, physical fatigue, and cognitive weariness, resulting from prolonged exposure to work-related stress. The authors review the accumulated evidence suggesting that burnout and the related concept of vital exhaustion are associated with increased risk of cardiovascular disease and cardiovascular-related events. The authors present evidence supporting several potential mechanisms linking burnout with ill health, including the metabolic syndrome, dysregulation of the hypothalamic-pituitary-adrenal axis along with sympathetic nervous system activation, sleep disturbances, systemic inflammation, impaired immunity functions, blood coagulation and fibrinolysis, and poor health behaviors. The association of burnout and vital exhaustion with these disease mediators suggests that their impact on health may be more extensive than currently indicated.

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Crossref · 10.1037/0033-2909.132.3.327

Cites

361 of 361 references verified0 citation errors · 0 not checkable

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Citations

Cites

Show all 370 references

Research works printed but not linked: 22

  1. Belkic, 2000, Multiple exposures: Toward a model of total occupational burden., Occupational Medicine (Philadelphia, Pa.), 15, 94
  2. Burke, 2000, Psychological burnout in organizations., 327
  3. 10.1001/jama.267.9.1244 · DOI · Paper page
  4. 10.2307/258593 · DOI
  5. Dougall, 2001, Stress, health and illness., 321
  6. 10.2307/1170690 · DOI
  7. 10.1097/00043798-200102000-00006 · DOI
  8. Hobfoll, 1993, Stress and burnout in the workplace: Conservation of resources., 41
  9. Kahn, 1992, Stress in organizations., Vol. 3, 571
  10. Karasek, 1990, Healthy work.
  11. 10.1037/1076-8998.1.1.9 · DOI
  12. Lazarus, 1999, Stress and emotion.
  13. Leiter, 2001, Burnout and health., 415
  14. Maslach, 1997, The truth about burnout.
  15. Metha, 2000, Epstein-Barr virus reactivation associated with diminished cell-mediated immunity in Antarctic expeditioners., Journal of Medical Virology, 61, 325
  16. 10.2307/259017 · DOI
  17. Pearlin, 1999, Stress and mental health: A conceptual overview., 161
  18. Pines, 1993, Burnout., 386
  19. 10.1210/jc.83.6.1853 · DOI
  20. 10.1037/0022-006x.70.3.548 · DOI
  21. 10.1037/1076-8998.4.1.37 · DOI
  22. Wheaton, 1999, The nature of Stressors., 176

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Metadata

Authors
Melamed, S., Shirom, A., Toker, S., Berliner, S., & Shapira, I.
Affiliations
  • Tel Aviv University (IL)
  • Tel Aviv Sourasky Medical Center (IL)
ORCID
Toker, Sharon
Venue
Psychological Bulletin
Publisher
American Psychological Association (APA)
Published
2006
Volume
132
Issue
3
Pages
327-353
ISSN
  • 0033-2909 (ISSN-L)
  • 1939-1455
DOI
10.1037/0033-2909.132.3.327
OpenAlex
W2062679887
Semantic Scholar
b3c222f37c85c1a78d7743b9720ca4407af2e1d7
Cited by
943
References
370
Citations by year
2026: 30 · 2025: 46 · 2024: 46 · 2023: 53 · 2022: 39 · 2021: 58 · 2020: 54 · 2019: 52 · 2018: 45 · 2017: 66 · 2016: 40 · 2015: 53 · 2014: 51 · 2013: 50 · 2012: 65
FWCI
4.74
Type
journal article
Language
en
Open access
closed
Locations
  • Psychological Bulletin (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Israel Science Foundation (962/02-1)
  • Government of Israel
Topics
  • Social Sciences › Psychology › Social Psychology › Stress and Burnout Research
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Occupational Health and Burnout
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Workplace Health and Well-being
Keywords
burnout, vital exhaustion, cardiovascular disease, occupational stress, emotional exhaustion, metabolic syndrome, hypothalamic-pituitary-adrenal axis, sympathetic activation, sleep disorders, systemic inflammation, coagulation, fibrinolysis, health behavior, causal pathways
MeSH terms
Burnout, Professional, Cardiovascular Diseases, Depression, Humans, Research Design

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