The DOI matches its Crossref record; 361 of the 370 references it cites were found in a registry or an index.
Burnout and risk of cardiovascular disease: Evidence, possible causal paths, and promising research directions.
Abstract
Burnout is characterized by emotional exhaustion, physical fatigue, and cognitive weariness, resulting from prolonged exposure to work-related stress. The authors review the accumulated evidence suggesting that burnout and the related concept of vital exhaustion are associated with increased risk of cardiovascular disease and cardiovascular-related events. The authors present evidence supporting several potential mechanisms linking burnout with ill health, including the metabolic syndrome, dysregulation of the hypothalamic-pituitary-adrenal axis along with sympathetic nervous system activation, sleep disturbances, systemic inflammation, impaired immunity functions, blood coagulation and fibrinolysis, and poor health behaviors. The association of burnout and vital exhaustion with these disease mediators suggests that their impact on health may be more extensive than currently indicated.
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“Extensive research shows that burnout is related to cognitive dysfunction,2 poor physical and mental health outcomes,3–6 and the use of more sick days.7”
From Being Mindful: A Long-term Investigation of an Interdisciplinary Course in Mindfulness (2019) · cites this paper as [3]
Citations
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Cited by
Sorted by citations
Getting to the “COR”: Understanding the Role of Resources in Conservation of Resources Theory
Halbesleben, J. R. B., Neveu, J.-P., Paustian-Underdahl, S. C., & Westman, M. (2014) · Journal of Management · doi:10.1177/0149206314527130 · Cited by 3,356
A Critical Review of the Job Demands-Resources Model: Implications for Improving Work and Health
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Job resources boost work engagement, particularly when job demands are high.
Bakker, A. B., Hakanen, J. J., Demerouti, E., & Xanthopoulou, D. (2007) · Journal of Educational Psychology · doi:10.1037/0022-0663.99.2.274 · Cited by 2,111
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Metadata
- Authors
- Melamed, S., Shirom, A., Toker, S., Berliner, S., & Shapira, I.
- Affiliations
- Tel Aviv University (IL)
- Tel Aviv Sourasky Medical Center (IL)
- ORCID
- Toker, Sharon
- Venue
- Psychological Bulletin
- Published
- 2006
- Volume
- 132
- Issue
- 3
- Pages
- 327-353
- ISSN
- 0033-2909 (ISSN-L)
- 1939-1455
- OpenAlex
- W2062679887
- Semantic Scholar
- b3c222f37c85c1a78d7743b9720ca4407af2e1d7
- Cited by
- 943
- References
- 370
- Citations by year
- 2026: 30 · 2025: 46 · 2024: 46 · 2023: 53 · 2022: 39 · 2021: 58 · 2020: 54 · 2019: 52 · 2018: 45 · 2017: 66 · 2016: 40 · 2015: 53 · 2014: 51 · 2013: 50 · 2012: 65
- FWCI
- 4.74
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Psychological Bulletin (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Israel Science Foundation (962/02-1)
- Government of Israel
- Topics
- Social Sciences › Psychology › Social Psychology › Stress and Burnout Research
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Occupational Health and Burnout
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Workplace Health and Well-being
- Keywords
- burnout, vital exhaustion, cardiovascular disease, occupational stress, emotional exhaustion, metabolic syndrome, hypothalamic-pituitary-adrenal axis, sympathetic activation, sleep disorders, systemic inflammation, coagulation, fibrinolysis, health behavior, causal pathways
- MeSH terms
- Burnout, Professional, Cardiovascular Diseases, Depression, Humans, Research Design
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