The DOI matches its Crossref record; 42 of the 43 references it cites were found in a registry or an index.
An oxytocin antagonist infused into the central nucleus of the amygdala increases maternal aggressive behavior
Open accessAbstract
Decreased oxytocin levels in the amygdalas of rat dams following chronic gestational cocaine exposure have been correlated with heightened maternal aggressive behavior. In this experiment, drug-naive dams were implanted with bilateral cannulas into the central nucleus of the amygdala (CNA) or control area and infused with 1,000 or 500 ng of an oxytocin antagonist (OTA) or buffer, 4 hr before testing. Behavior was compared among dams infused with OTA into target areas just outside the CNA and cocaine-treated dams (infused with buffer). Dams infused with 1,000 ng OTA attacked intruders significantly more often than buffer-infused dams. OTA did not affect other behaviors, suggesting that disruption of oxytocin activity in the CNA may be sufficient to selectively alter maternal aggressive behavior.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Chronic ICV administration of oxytocin receptor antagonists can reduce maternal aggression in strains of rats exhibiting high anxiety and higher levels of defensive aggression (Bosch et al., 2005 but see Lubin et al., 2003).”
From Oxytocin, motivation and the role of dopamine (2014) · cites this paper as Lubin et al., 2003
Citations
Cites
The Rat Brain in Stereotaxic Coordinates
Paxinos, G., & Watson, C. (1983) · Elsevier eBooks · doi:10.1016/c2009-0-63235-9 · Cited by 28,585
The Physiology of Reproduction
Legendre, M., & Jalabert, B. (1988) · Annals of Internal Medicine · doi:10.7326/0003-4819-109-2-176_1 · Cited by 7,876
AChE-stained horizontal sections of the rat brain in stereotaxic coordinates
Paxinos, G., WATSON, C. R. R., & Emson, P. C. (1980) · Journal of Neuroscience Methods · doi:10.1016/0165-0270(80)90021-7 · Cited by 4,514
Swanson, L. W., & Petrovich, G. D. (1998) · Trends in Neurosciences · doi:10.1016/s0166-2236(98)01265-x · Cited by 1,351
Oxytocin in the Medial Amygdala is Essential for Social Recognition in the Mouse
Ferguson, J. N., Aldag, J. M., Insel, T. R., & Young, L. J. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-20-08278.2001 · Cited by 1,043
An Introduction to Behavioral Endocrinology
Nelson, R. J. (1994) · Cited by 749
The physiology of reproduction
Chalmers, J. A. (1973) · Springer eBooks · doi:10.1007/978-94-010-2351-1_3 · Cited by 624
Pedersen, C. A., Caldwell, J. D., Walker, C., Ayers, G., & Mason, G. A. (1994) · Behavioral Neuroscience · doi:10.1037/0735-7044.108.6.1163 · Cited by 475
Richard, P., Moos, F., & Freund-Mercier, M. J. (1991) · Physiological Reviews · doi:10.1152/physrev.1991.71.2.331 · Cited by 379 · cited 1×
“Projections from the CNA synapse on relevant brainstem and spinal cord nuclei that regulate autonomic activity (Richard et al., 1991).”
BackgroundAmygdaloid inhibition of maternal behavior in the nulliparous female rat☆
FLEMING, A., Vaccarino, F. J., & Luebke, C. (1980) · Physiology & Behavior · doi:10.1016/0031-9384(80)90377-7 · Cited by 271
Research works printed but not linked: 1
- Numan, 1994, Maternal behavior., 221
Cited by
Sorted by citations
Evoked axonal oxytocin release in the central amygdala attenuates fear response
Knobloch, H. S., Charlet, A., Hoffmann, L. C., Eliava, M., Khrulev, S., Cetin, A. H., Osten, P., Schwarz, M. K., Seeburg, P. H., Stoop, R., et al. (2012) · Neuron · doi:10.1016/j.neuron.2011.11.030 · Cited by 1,049
Landgraf, R., & Neumann, I. D. (2004) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2004.05.001 · Cited by 1,059
Oxytocin: The Great Facilitator of Life
Lee, H.-J., Macbeth, A. H., Pagani, J., & Young, W. S. (2009) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2009.04.001 · Cited by 1,037
Vasopressin and Oxytocin Excite Distinct Neuronal Populations in the Central Amygdala
Huber, D., Veinante, P., & Stoop, R. (2005) · Science · doi:10.1126/science.1105636 · Cited by 804
Oxytocin Attenuates Amygdala Reactivity to Fear in Generalized Social Anxiety Disorder
Labuschagne, I., Phan, K. L., Wood, A., Angstadt, M., Chua, P., Heinrichs, M., Stout, J. C., & Nathan, P. J. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2010.123 · Cited by 549
Metadata
- Authors
- Lubin, D. A., Elliot, J. C., Black, M. C., & Johns, J. M.
- Affiliations
- University of North Carolina at Chapel Hill (US)
- Venue
- Behavioral Neuroscience
- Published
- 2003
- Volume
- 117
- Issue
- 2
- Pages
- 195-201
- ISSN
- 0735-7044 (ISSN-L)
- 1939-0084
- PMC
- PMC3109068
- OpenAlex
- W2040553957
- Cited by
- 145
- References
- 43
- Citations by year
- 2026: 1 · 2025: 4 · 2024: 2 · 2023: 4 · 2022: 1 · 2021: 6 · 2020: 5 · 2019: 7 · 2018: 2 · 2017: 7 · 2016: 4 · 2015: 9 · 2014: 5 · 2013: 7 · 2012: 10
- FWCI
- 14.83
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Behavioral Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Carolina Digital Repository (University of North Carolina at Chapel Hill) (submittedVersion)
- UNC Libraries
- Funders
- National Institutes of Health
- National Institute on Drug Abuse (DA13283-01A1, R01DA013362, DA13362-01, R29DA008456, R01DA013283)
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuropeptides and Animal Physiology
- Keywords
- oxytocin antagonist, central amygdala, maternal aggression, maternal behavior, intruder, oxytocin, rats
- MeSH terms
- Aggression, Amygdala, Anesthetics, Local, Animals, Behavior, Animal, Cocaine, Dose-Response Relationship, Drug, Female, Hormone Antagonists, Maternal Behavior, Oxytocin, Pregnancy, Time Factors, Rats, Sprague-Dawley, Ventral Tegmental Area, Rats
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
