Central effects of oxytocin

Richard, P.; Moos, F.; Freund-Mercier, M. J.

doi:10.1152/physrev.1991.71.2.331

Cited by 380Neuroendocrine regulation and behaviorNeuropeptides and Animal PhysiologyNeurotransmitter Receptor Influence on Behavior

Central effects of oxytocin

Richard, P., Moos, F., Freund-Mercier, M. J.·1991·Physiological Reviews

DOI 10.1152/physrev.1991.71.2.331

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Optogenetic stimulation of oxytocinergic fibers may lead to corelease of other neurotransmitters or neuromodulators that regulate inhibition, such as glutamate.
“It is also possible that optogenetic stimulation of oxytocinergic fibers leads to corelease of other neurotransmitters or neuromodulators that regulate inhibition, such as glutamate (Kendrick et al., 1988;Richard et al., 1991).”
From A distributed network for social cognition enriched for oxytocin receptors (2016) · cites this paper as Richard et al., 1991

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Localization of oxytocin receptor messenger ribonucleic acid in the rat brain.
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Expression of G Protein-Coupled Receptor-30, a G Protein-Coupled Membrane Estrogen Receptor, in Oxytocin Neurons of the Rat Paraventricular and Supraoptic Nuclei
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Hypothalamic Paraventricular Nucleus Modulates Maternal Aggression in Rats: Effects of Ibotenic Acid Lesion and Oxytocin Antisense
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<scp>O</scp>xytocin modulation of neural circuits for social behavior
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Background
Oxytocin decreases carrageenan induced inflammation in rats
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“Oxytocin is mainly associated with uterine contraction during parturition and the milk-ejection reflex during lactation, but it is also implicated in for example cardiovascular and natriuretic regulation [9,15,17], various behaviors such as maternal, social and sexual behavior [3] as well as modulation of the release…”
Background
A single social defeat experience selectively stimulates the release of oxytocin, but not vasopressin, within the septal brain area of male rats
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Effects of Sucking and Skin-to-Skin Contact on Maternal ACTH and Cortisol Levels During the Second Day Postpartum—Influence of Epidural Analgesia and Oxytocin in the Perinatal Period
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“29,30 The oxytocin release caused by skin-to-skin contact may be restricted to parvocellular oxytocin neurons projecting to the nucleus tractus solitarius and must not necessarily involve release of oxytocin from the magnocellular neurons and a consequent rise of circulating oxytocin levels.”
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Vasopressin‐induced intracellular Ca2+ increase in isolated rat supraoptic cells.
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“It is known for its hormonal functions during labor, where it causes uterine contractions, and during lactation, where it causes contractions of the myoepithelial cells surrounding the alveoli to induce milk letdown in response to infant suckling during breastfeeding (Richard et al. 1991).”
Background
Central Nervous System Control of Gastrointestinal Motility and Secretion and Modulation of Gastrointestinal Functions
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60 YEARS OF NEUROENDOCRINOLOGY: The posterior pituitary, from Geoffrey Harris to our present understanding
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“Several investigations point toward a role of central oxytocinergic neurons in higher level control of cardiovascular function through both sympathetic and parasympathetic pathways [40] [41] [42] [43] [44] [45] [46] [47] [48] [49] [50] [51].”
Background

Authors: Richard, P., Moos, F., & Freund-Mercier, M. J.
Affiliations: Université de Strasbourg (FR)
Laboratoire de Physiologie, Universite Louis Pasteur, Strasbourg,France.
ORCID: Richard, P.
Venue: Physiological Reviews
Publisher: American Physiological Society
Published: 1991-04-01
Volume: 71
Issue: 2
Pages: 331-370
ISSN: 0031-9333 (ISSN-L)
1522-1210
DOI: 10.1152/physrev.1991.71.2.331
OpenAlex: W2168650408
Cited by: 379
References: 0
Citations by year: 2026: 5 · 2025: 1 · 2024: 8 · 2023: 7 · 2022: 12 · 2021: 11 · 2020: 3 · 2019: 12 · 2018: 21 · 2017: 5 · 2016: 5 · 2015: 10 · 2014: 6 · 2013: 8 · 2012: 6
FWCI: 26.24
Type: journal article
Language: en
Open access: closed
Locations: Physiological Reviews (publishedVersion)
PubMed (publishedVersion)
Topics: Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuropeptides and Animal Physiology
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Keywords: oxytocin, central nervous system, neuroendocrine regulation, hypothalamus, neurosecretion, social behavior
MeSH terms: Animals, Behavior, Animal, Binding Sites, Brain, Electrophysiology, Humans, Neuronal Plasticity, Neurons, Oxytocin, Neurotransmitter Agents

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