The DOI matches its Crossref record; 55 of the 57 references it cites were found in a registry or an index.
Patterns of developmental trajectories in toddlers with autism spectrum disorder
Open accessAbstract
OBJECTIVE: Our objective was to follow toddlers referred for risk of autism, using standardized observational measures administered frequently from age 18 months to age 36 months. METHOD: Sixty-five children who were consecutive referrals and 13 children from other research projects were seen approximately every 2 months, from age 18 months to age 36 months, for standardized assessments and clinical judgments by the same examiner and every 6 months by an examiner blind to previous scores. RESULTS: Thirty children never received an autism spectrum disorder (ASD) diagnosis; 48 children (all referrals) received at least 1 diagnosis of ASD. The best trajectory typology, using Autism Diagnostic Observation Schedule (ADOS) scores, revealed 4 trajectory classes with high probabilities for fit to the most likely class: severe persistent (21%), worsening (21%), improving (19%), and nonspectrum (40%). Classes differed by trajectories in verbal and nonverbal mental ages; never-ever ASD groups differed on Autism Diagnostic Interview-Revised (ADI-R) domain scores and clinician judgments, but improving-worsening trajectory groups did not. CONCLUSIONS: The results replicated the findings from studies of infants whose siblings have autism and infants whose siblings do not have autism, suggesting variability in early trajectories and supporting the need for early identification, regular monitoring, and standardized assessments of young children suspected of having ASD.
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Cites
Diagnostic and Statistical Manual of Mental Disorders
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Lord, C., Risi, S., Lambrecht, L., Cook, E. H., Leventhal, B. L., DiLavore, P. C., Pickles, A., & Rutter, M. (2000) · Journal of Autism and Developmental Disorders · doi:10.1023/a:1005592401947 · Cited by 7,520
Self-citationDawson, G., Rogers, S., Munson, J., Smith, M., Winter, J., Greenson, J., Donaldson, A., & Varley, J. (2010) · Pediatrics · doi:10.1542/peds.2009-0958 · Cited by 2,835
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Adult outcome for children with autism
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Behavioral manifestations of autism in the first year of life
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The Autism Diagnostic Observation Schedule: Revised Algorithms for Improved Diagnostic Validity
Gotham, K., Risi, S., Pickles, A., & Lord, C. (2007) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-006-0280-1 · Cited by 1,161
Self-citationA Prospective Study of the Emergence of Early Behavioral Signs of Autism
Ozonoff, S., Iosif, A.-M., Baguio, F., Cook, I. C., Hill, M. M., Hutman, T., Rogers, S. J., Rozga, A., Sangha, S., Sigman, M., et al. (2010) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2009.11.009 · Cited by 1,011
Generalized Multilevel Structural Equation Modeling
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Research works printed but not linked: 1
- Lord C Luyster R Gotham K Guthrie W (in press) The Autism Diagnostic Observation Schedule, Toddler Module Los Angeles, CA Western Psychological Services
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Parent-Implemented Social Intervention for Toddlers With Autism: An RCT
Wetherby, A. M., Guthrie, W., Woods, J. J., Schatschneider, C. W., Holland, R. D., Morgan, L., & Lord, C. (2014) · PEDIATRICS · doi:10.1542/peds.2014-0757 · Cited by 421
Self-citationGuthrie, W., Swineford, L. B., Nottke, C., & Wetherby, A. M. (2013) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.12008 · Cited by 366
Self-citationAnnual research review: re-thinking the classification of autism spectrum disorders
Lord, C., & Jones, R. M. (2012) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2012.02547.x · Cited by 290
Self-citationTrajectories of Autism Severity in Children Using Standardized ADOS Scores
Gotham, K., Pickles, A., & Lord, C. (2012) · Pediatrics · doi:10.1542/peds.2011-3668 · Cited by 271
Self-citationThe Autism Diagnostic Observation Schedule, Toddler Module: Standardized Severity Scores
Esler, A., Bal, V. H., Guthrie, W., Wetherby, A. M., Weismer, S. E., & Lord, C. (2015) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-015-2432-7 · Cited by 286
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Metadata
- Authors
- Lord, C., Luyster, R., Guthrie, W., & Pickles, A.
- Affiliations
- NewYork–Presbyterian Hospital (US)
- Harvard University (US)
- Florida State University (US)
- University of London (GB)
- Venue
- Journal of Consulting and Clinical Psychology
- Published
- 2012-06
- Volume
- 80
- Issue
- 3
- Pages
- 477-489
- ISSN
- 0022-006X (ISSN-L)
- 1939-2117
- PMC
- PMC3365612
- OpenAlex
- W2022069611
- Cited by
- 142
- References
- 57
- Citations by year
- 2026: 5 · 2025: 7 · 2024: 11 · 2023: 8 · 2022: 17 · 2021: 11 · 2020: 13 · 2019: 6 · 2018: 8 · 2017: 5 · 2016: 10 · 2015: 14 · 2014: 13 · 2013: 11 · 2012: 3
- FWCI
- 6.71
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Consulting and Clinical Psychology (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Research Portal (King's College London) (submittedVersion)
- Funders
- Department of Education (H324 C030112)
- National Institute of Mental Health (R01 MH066496)
- Simons Foundation
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
- Social Sciences › Psychology › Developmental and Educational Psychology › Child and Animal Learning Development
- Keywords
- autism spectrum disorder, toddlers, developmental trajectories, autism risk, early detection, early intervention, mental age, Autism Diagnostic Observation Schedule, ADI-R, clinical judgment, siblings of autistic children
- MeSH terms
- Child Development, Child Development Disorders, Pervasive, Child, Preschool, Female, Humans, Infant, Intelligence, Longitudinal Studies, Male, Psychometrics, Social Behavior, Siblings
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