The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.
DREADDS: Use and application in behavioral neuroscience.
Open accessAbstract
Technological advances over the last decade are changing the face of behavioral neuroscience research. Here we review recent work on the use of one such transformative tool in behavioral neuroscience research, chemogenetics (or Designer Receptors Exclusively Activated by Designer Drugs, DREADDS). As transformative technologies such as DREADDs are introduced, applied, and refined, their utility in addressing complex questions about behavior and cognition becomes clear and exciting. In the behavioral neuroscience field, remarkable new findings now regularly appear as a result of the ability to monitor and intervene in neural processes with high anatomical precision as animals behave in complex task environments. As these new tools are applied to behavioral questions, individualized procedures for their use find their way into diverse labs. Thus, "tips of the trade" become important for wide dissemination not only for laboratories that are using the tools but also for those who are interested in incorporating them into their own work. Our aim is to provide an up-to-date perspective on how the DREADD technique is being used for research on learning and memory, decision making, and goal-directed behavior, as well as to provide suggestions and considerations for current and future users based on our collective experience. (PsycINFO Database Record
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Cites
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InfluentialNeuron-type-specific signals for reward and punishment in the ventral tegmental area
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Cited by
Manvich, D. F., Webster, K. A., Foster, S. L., Farrell, M. S., Ritchie, J. C., Porter, J. H., & Weinshenker, D. (2018) · Scientific Reports · doi:10.1038/s41598-018-22116-z · Cited by 367
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Ecological validity of social interaction tests in rats and mice
Kondrakiewicz, K., Kostecki, M., Szadzińska, W., & Knapska, E. (2019) · Genes, Brain and Behavior · doi:10.1111/gbb.12525 · Cited by 136
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Metadata
- Authors
- Smith, K. S., Bucci, D. J., Luikart, B. W., & Mahler, S. V.
- Venue
- Behavioral Neuroscience
- Published
- 2016-04
- Volume
- 130
- Issue
- 2
- Pages
- 137-155
- ISSN
- 0735-7044 (ISSN-L)
- 1939-0084
- OpenAlex
- W2413686208
- Cited by
- 239
- References
- 26
- FWCI
- 12.38
- Type
- journal article
- Language
- en
- Open access
- hybrid
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