Cited by 130Memory and Neural MechanismsMemory Processes and InfluencesPosttraumatic Stress Disorder Research

The DOI matches its Crossref record; 107 of the 107 references it cites were found in a registry or an index.

Harnessing reconsolidation to weaken fear and appetitive memories: A meta-analysis of post-retrieval extinction effects.

Open access

Kredlow, M. Alexandra, Unger, Leslie D., Otto, Michael W.·2016·Psychological Bulletin

Open this paper in CoChat — free account

Abstract

A new understanding of the mechanisms of memory retrieval and reconsolidation holds the potential for improving exposure-based treatments. Basic research indicates that following fear extinction, safety and fear memories may compete, raising the possibility of return of fear. One possible solution is to modify original fear memories through reconsolidation interference, reducing the likelihood of return of fear. Postretrieval extinction is a behavioral method of reconsolidation interference that has been explored in the context of conditioned fear and appetitive memory paradigms. This meta-analysis examines the magnitude of postretrieval extinction effects and potential moderators of these effects. A PubMed and PsycINFO search was conducted through June 2014. Sixty-three comparisons examining postretrieval extinction for preventing the return of fear or appetitive responses in animals or humans met inclusion criteria. Postretrieval extinction demonstrated a significant, small-to-moderate effect (g = .40) for further reducing the return of fear in humans and a significant, large effect (g = 0.89) for preventing the return of appetitive responses in animals relative to standard extinction. For fear outcomes in animals, effects were small (g = 0.21) and nonsignificant, but moderated by the number of animals housed together and the duration of time between postretrieval extinction/extinction and test. Across paradigms, these findings support the efficacy of this preclinical strategy for preventing the return of conditioned fear and appetitive responses. Overall, findings to date support the continued translation of postretrieval extinction research to human and clinical applications, with particular application to the treatment of anxiety, traumatic stress, and substance use disorders.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1037/bul0000034

Cites

107 of 107 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Statistical power analysis for the behavioral sciences
Cohen, J. (1990) · Computers Environment and Urban Systems · doi:10.1016/0198-9715(90)90050-4 · Cited by 65,417
Trim and Fill: A Simple Funnel‐Plot–Based Method of Testing and Adjusting for Publication Bias in Meta‐Analysis
Duval, S., & Tweedie, R. (2000) · Biometrics · doi:10.1111/j.0006-341x.2000.00455.x · Cited by 14,099
Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning.
Phillips, R. G., & LeDoux, J. E. (1992) · Behavioral Neuroscience · doi:10.1037/0735-7044.106.2.274 · Cited by 3,292
Fear memories require protein synthesis in the amygdala for reconsolidation after retrieval
Nader, K., Schafe, G. E., & Le Doux, J. E. (2000) · Nature · doi:10.1038/35021052 · Cited by 2,706
A cortical–hippocampal system for declarative memory
Eichenbaum, H. (2000) · Nature reviews. Neuroscience · doi:10.1038/35036213 · Cited by 1,817
Sex bias in neuroscience and biomedical research
Beery, A. K., & Zucker, I. (2011) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2010.07.002 · Cited by 1,763
Context, ambiguity, and unlearning: sources of relapse after behavioral extinction
Bouton, M. E. (2002) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01546-9 · Cited by 1,662
Cognitive-Behavioral Therapy for Adult Anxiety Disorders: A Meta-Analysis of Randomized Placebo-Controlled Trials
Hoffman, S. G., & Smits, J. A. J. (2008) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v69n0415 · Cited by 1,420
Double Dissociation of Conditioning and Declarative Knowledge Relative to the Amygdala and Hippocampus in Humans
Bechara, A., Tranel, D., Damasio, H., Adolphs, R., Rockland, C., & Damasio, A. R. (1995) · Science · doi:10.1126/science.7652558 · Cited by 1,400
Variance imputation for overviews of clinical trials with continuous response
Follmann, D. A., Elliott, P., Suh, I., & Cutler, J. A. (1992) · Journal of Clinical Epidemiology · doi:10.1016/0895-4356(92)90054-q · Cited by 1,391

Show all 107 references

Research works printed but not linked: 1

Chan WYM The effects of retrieval-extinction training on the restoration of Pavlovian conditioned fear Unpublished Ph.D. thesis 2014 Australia University of New South Wales (UNSW)

Sorted by citations

An Update on Memory Reconsolidation Updating
Lee, J. L. C., Nader, K., & Schiller, D. (2017) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2017.04.006 · Cited by 557
Anxiety disorders
Craske, M. G., Stein, M. B., Eley, T. C., Milad, M. R., Holmes, A., Rapee, R. M., & Wittchen, H.-U. (2017) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2017.24 · Cited by 652
What meta-analyses reveal about the replicability of psychological research.
Stanley, T. D., Carter, E. C., & Doucouliagos, H. (2018) · Psychological Bulletin · doi:10.1037/bul0000169 · Cited by 307
Promoting memory consolidation during sleep: A meta-analysis of targeted memory reactivation
Hu, X., Cheng, L. Y., Chiu, M. H., & Paller, K. A. (2020) · Psychological Bulletin · doi:10.1037/bul0000223 · Cited by 232
Human memory reconsolidation: A guiding framework and critical review of the evidence.
Elsey, J. W. B., Van Ast, V. A., & Kindt, M. (2018) · Psychological Bulletin · doi:10.1037/bul0000152 · Cited by 199
The computational nature of memory modification
Gershman, S. J., Monfils, M.-H., Norman, K. A., & Niv, Y. (2017) · eLife · doi:10.7554/elife.23763 · Cited by 172
Memory Reconsolidation Interference as an Emerging Treatment for Emotional Disorders: Strengths, Limitations, Challenges, and Opportunities
Beckers, T., & Kindt, M. (2017) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-032816-045209 · Cited by 184
Memory boundaries: opening a window inspired by reconsolidation to treat anxiety, trauma-related, and addiction disorders
Monfils, M., & Holmes, E. A. (2018) · The Lancet Psychiatry · doi:10.1016/s2215-0366(18)30270-0 · Cited by 150
Exposure therapy augmentation: A review and extension of techniques informed by an inhibitory learning approach
Weisman, J. S., & Rodebaugh, T. L. (2018) · Clinical Psychology Review · doi:10.1016/j.cpr.2017.10.010 · Cited by 143
Current practices in meta‐regression in psychology, education, and medicine
Tipton, E., Pustejovsky, J. E., & Ahmadi, H. (2019) · Research Synthesis Methods · doi:10.1002/jrsm.1339 · Cited by 133
Measuring learning in human classical threat conditioning: Translational, cognitive and methodological considerations
Ojala, K. E., & Bach, D. R. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.04.019 · Cited by 127
An affective neuroscience model of boosting resilience in adults
Tabibnia, G. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.05.005 · Cited by 115
Multiple memory systems, multiple time points: How science can inform treatment to control the expression of unwanted emotional memories
Visser, R. M., Lau-Zhu, A., Henson, R. N., & Holmes, E. A. (2018) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2017.0209 · Cited by 95
New learning and unlearning: strangers or accomplices in threat memory attenuation?
Clem, R. L., & Schiller, D. (2016) · Trends in Neurosciences · doi:10.1016/j.tins.2016.03.003 · Cited by 90
Modeling cocaine relapse in rodents: Behavioral considerations and circuit mechanisms
Farrell, M. R., Schoch, H., & Mahler, S. V. (2018) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2018.01.002 · Cited by 90
Modulation of naturalistic maladaptive memories using behavioural and pharmacological reconsolidation-interfering strategies: A systematic review and meta-analysis of clinical and 'sub-clinical' studies
Walsh, K. H., Das, R. K., Saladin, M. E., & Kamboj, S. K. (2018) · Psychopharmacology · doi:10.1007/s00213-018-4983-8 · Cited by 77
Disruption of human fear reconsolidation using imaginal and in vivo extinction
Ågren, T., Björkstrand, J., & Fredrikson, M. G. (2016) · Behavioural Brain Research · doi:10.1016/j.bbr.2016.11.014 · Cited by 79
No persistent attenuation of fear memories in humans: A registered replication of the reactivation-extinction effect
Chalkia, A., Schroyens, N., Leng, L., Vanhasbroeck, N., Zenses, A., Oudenhove, L. V., & Beckers, T. (2020) · Cortex · doi:10.1016/j.cortex.2020.04.017 · Cited by 77
In search for boundary conditions of reconsolidation: a failure of fear memory interference
Schroyens, N., Beckers, T., & Kindt, M. (2017) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2017.00065 · Cited by 70
Psychophysiological modelling and the measurement of fear conditioning
Bach, D. R., & Melinščak, F. (2020) · Behaviour Research and Therapy · doi:10.1016/j.brat.2020.103576 · Cited by 72
Forgetting and emotion regulation in mental health, anxiety and depression
Nørby, S. (2017) · Memory · doi:10.1080/09658211.2017.1346130 · Cited by 72
From Extinction Learning to Anxiety Treatment: Mind the Gap
Carpenter, J. K., Pinaire, M., & Hofmann, S. G. (2019) · Brain Sciences · doi:10.3390/brainsci9070164 · Cited by 77
Reconsolidation of traumatic memories for PTSD: a randomized controlled trial of 74 male veterans
Gray, R., Budden-Potts, D., & Bourke, F. (2019) · Psychotherapy Research · doi:10.1080/10503307.2017.1408973 · Cited by 66
A preregistered, direct replication attempt of the retrieval-extinction effect in cued fear conditioning in rats
Luyten, L., & Beckers, T. (2017) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2017.07.014 · Cited by 66
Preventing the return of fear in humans using reconsolidation update mechanisms: A verification report of Schiller et al. (2010)
Chalkia, A., Oudenhove, L. V., & Beckers, T. (2020) · Cortex · doi:10.1016/j.cortex.2020.03.031 · Cited by 61
Propofol-induced deep sedation reduces emotional episodic memory reconsolidation in humans
Galarza-Vallejo, A., Kroes, M. C. W., Rey, E., Acedo, M. V., Moratti, S., Fernández, G., & Strange, B. A. (2019) · Science Advances · doi:10.1126/sciadv.aav3801 · Cited by 51
Clinical Translation of Memory Reconsolidation Research: Therapeutic Methodology for Transformational Change by Erasing Implicit Emotional Learnings Driving Symptom Production
Ecker, B. (2018) · International Journal of Neuropsychotherapy · doi:10.12744/ijnpt.2018.0001-0092 · Cited by 56
Reminder duration determines threat memory modification in humans
Hu, J., Wang, W., Homan, P., Wang, P., Zheng, X., & Schiller, D. (2018) · Scientific Reports · doi:10.1038/s41598-018-27252-0 · Cited by 50
Think twice, it’s all right: Long lasting effects of disrupted reconsolidation on brain and behavior in human long-term fear
Björkstrand, J., Agren, T., Åhs, F., Frick, A., Larsson, E.-M., Hjorth, O., Furmark, T., & Fredrikson, M. (2017) · Behavioural Brain Research · doi:10.1016/j.bbr.2017.02.016 · Cited by 42
Examining the Inter-relations of Depression, Physical Function, and Cognition with Subjective Sleep Parameters among Stroke Survivors: A Cross-sectional Analysis
Davis, J. C., Falck, R. S., Best, J. R., Chan, P., Doherty, S., & Liu-Ambrose, T. Y. L. (2019) · Journal of Stroke and Cerebrovascular Diseases · doi:10.1016/j.jstrokecerebrovasdis.2019.04.010 · Cited by 44
Consensus design of a calibration experiment for human fear conditioning
Bach, D. R., Sporrer, J. K., Abend, R., Beckers, T., Dunsmoor, J. E., Fullana, M. A., Gamer, M., Gee, D. G., Hamm, A. O., Hartley, C. A., et al. (2023) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2023.105146 · Cited by 47
Use of a Brief Fear Memory Reactivation Procedure for Enhancing Exposure Therapy
Telch, M. J., York, J., Lancaster, C. L., & Monfils, M. H. (2017) · Clinical Psychological Science · doi:10.1177/2167702617690151 · Cited by 40
Neurochemical and molecular mechanisms underlying the retrieval-extinction effect
Cahill, E., & Milton, A. L. (2019) · Psychopharmacology · doi:10.1007/s00213-018-5121-3 · Cited by 44
Shifting from fear to safety through deconditioning-update
Popik, B., Amorim, F. E., Amaral, O. B., & Alvares, L. D. O. (2020) · eLife · doi:10.7554/elife.51207 · Cited by 47
Extinction during reconsolidation eliminates recovery of fear conditioned to fear-irrelevant and fear-relevant stimuli
Thompson, A., & Lipp, O. V. (2017) · Behaviour Research and Therapy · doi:10.1016/j.brat.2017.01.017 · Cited by 44
The role of prediction error and memory destabilization in extinction of cued-fear within the reconsolidation window
Cahill, E. N., Wood, M. A., Everitt, B. J., & Milton, A. L. (2019) · Neuropsychopharmacology · doi:10.1038/s41386-018-0299-y · Cited by 40
Drug memory reconsolidation: from molecular mechanisms to the clinical context
Milton, A. L. (2023) · Translational Psychiatry · doi:10.1038/s41398-023-02666-1 · Cited by 35
Behavioral, neurobiological, and neurochemical mechanisms of ethanol self-administration: A translational review
Vena, A. A., Zandy, S. L., Cofresí, R. U., & Gonzales, R. A. (2020) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2020.107573 · Cited by 33
Exploring the boundaries of post-retrieval extinction in healthy and anxious individuals
Kredlow, M. A., Orr, S. P., & Otto, M. W. (2018) · Behaviour Research and Therapy · doi:10.1016/j.brat.2018.06.010 · Cited by 35
Self-citation
Evaluation of the reconsolidation of traumatic memories protocol for the treatment of PTSD: a randomized, wait-list-controlled trial
Tylee, D. S., Gray, R. M., Glatt, S. J., & Bourke, F. (2017) · Journal of Military Veteran and Family Health · doi:10.3138/jmvfh.4120 · Cited by 32
Contributions from neuroscience to the practice of Cognitive Behaviour Therapy: Translational psychological science in service of good practice
Raedt, R. D. (2020) · Behaviour Research and Therapy · doi:10.1016/j.brat.2019.103545 · Cited by 32
Memory persistence: from fundamental mechanisms to translational opportunities
Merlo, S. A., Belluscio, M., Pedreira, M. E., & Merlo, E. (2024) · Translational Psychiatry · doi:10.1038/s41398-024-02808-z · Cited by 35
A review of boundary conditions and variables involved in the prevention of return of fear after post-retrieval extinction
Zuccolo, P. F., & Hunziker, M. H. L. (2019) · Behavioural Processes · doi:10.1016/j.beproc.2019.01.011 · Cited by 32
Effects of acute exercise on fear extinction in rats and exposure therapy in humans: Null findings from five experiments
Jacquart, J., Roquet, R. F., Papini, S., Powers, M. B., Rosenfield, D., Smits, J. A. J., & Monfils, M. (2017) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2017.05.010 · Cited by 35
Postretrieval Extinction Attenuates Alcohol Cue Reactivity in Rats
Cofresí, R. U., Lewis, S. M., Chaudhri, N., Lee, H. J., Monfils, M., & Gonzales, R. A. (2017) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.13323 · Cited by 31
Psychedelics and reconsolidation of traumatic and appetitive maladaptive memories: focus on cannabinoids and ketamine
Fattore, L., Piva, A., Zanda, M. T., Fumagalli, G. F., & Chiamulera, C. (2017) · Psychopharmacology · doi:10.1007/s00213-017-4793-4 · Cited by 26
Behavioral disruption of memory reconsolidation: From bench to bedside and back again.
Drexler, S. M., & Wolf, O. T. (2018) · Behavioral Neuroscience · doi:10.1037/bne0000231 · Cited by 29
Memory creation and modification: Enhancing the treatment of psychological disorders.
Kredlow, M. A., Eichenbaum, H., & Otto, M. W. (2018) · American Psychologist · doi:10.1037/amp0000185 · Cited by 25
Self-citation
Effect of d-cycloserine on fear extinction training in adults with social anxiety disorder
Hofmann, S. G., Papini, S., Carpenter, J. K., Otto, M. W., Rosenfield, D., Dutcher, C. D., Dowd, S. M., Lewis, M., Witcraft, S. M., Pollack, M. H., et al. (2019) · PLoS ONE · doi:10.1371/journal.pone.0223729 · Cited by 27
Self-citation
Limited replicability of drug-induced amnesia after contextual fear memory retrieval in rats
Schroyens, N., Alfei, J. M., Schnell, A. E., Luyten, L., & Beckers, T. (2019) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2019.107105 · Cited by 27
The evidence for and against reactivation-induced memory updating in humans and nonhuman animals
Jardine, K. H., Huff, A. E., Wideman, C. E., McGraw, S. D., & Winters, B. D. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104598 · Cited by 32
Threat Memory Reminder Under Matrix Metalloproteinase 9 Inhibitor Doxycycline Globally Reduces Subsequent Memory Plasticity
Bach, D. R., Naef, M., Deutschmann, M., Tyagarajan, S. K., & Quednow, B. B. (2019) · Journal of Neuroscience · doi:10.1523/jneurosci.1285-19.2019 · Cited by 23
Post-retrieval extinction in adolescence prevents return of juvenile fearPreprint
Jones, C. E., & Monfils, M. (2016) · Learning & Memory · doi:10.1101/lm.043281.116 · Cited by 25
The Effects of β-Adrenergic Blockade on the Degrading Effects of Eye Movements on Negative Autobiographical Memories
Littel, M., Kenemans, J. L., Baas, J. M. P., Logemann, H. N. A., Rijken, N., Remijn, M., Hassink, R. J., Engelhard, I. M., & van den Hout, M. (2017) · Biological Psychiatry · doi:10.1016/j.biopsych.2017.03.012 · Cited by 23
Destabilizing Different Strengths of Fear Memories Requires Different Degrees of Prediction Error During Retrieval
Chen, W., Li, J., Xu, L., Zhao, S., Fan, M., & Zheng, X. (2021) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2020.598924 · Cited by 23
Using collaboration networks to identify authorship dependence in meta‐analysis results
Moulin, T. C., & Amaral, O. B. (2020) · Research Synthesis Methods · doi:10.1002/jrsm.1430 · Cited by 22
Preventing the return of fear using reconsolidation updating and methylene blue is differentially dependent on extinction learning
Auchter, A., Shumake, J., Gonzalez-Lima, F., & Monfils, M. (2017) · Scientific Reports · doi:10.1038/srep46071 · Cited by 22
Does exercise augment operant and Pavlovian extinction: A meta-analysis
Roquet, R. F., & Monfils, M. (2017) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2017.09.018 · Cited by 22
Targeting the reconsolidation of traumatic memories with a brief 2-session imaginal exposure intervention in post-traumatic stress disorder
Vermes, J. S., Ayres, R., Goés, A. S., Real, N. D., Araújo, Á. C., Schiller, D., Neto, F. L., & Corchs, F. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.06.052 · Cited by 24
The three R's of scientific integrity: Replicability, reproducibility, and robustness
McIntosh, R. D., & Chambers, C. (2020) · Cortex · doi:10.1016/j.cortex.2020.04.019 · Cited by 20
Who is studied in de novo fear conditioning paradigms? An examination of demographic and stimulus characteristics predicting fear learning
Kredlow, M. A., Orr, S. P., & Otto, M. W. (2018) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2018.05.008 · Cited by 20
Self-citation
Extinction after fear memory reactivation fails to eliminate renewal in rats
Goode, T. D., Holloway-Erickson, C. M., & Maren, S. (2017) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2017.03.001 · Cited by 21
The Computational Nature of Memory ModificationPreprint
Gershman, S. J., Monfils, M., Norman, K. A., & Niv, Y. (2016) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/036442 · Cited by 21
Using model systems to understand errant plasticity mechanisms in psychiatric disorders
Averbeck, B. B., & Chafee, M. V. (2016) · Nature Neuroscience · doi:10.1038/nn.4413 · Cited by 18
Meta-analysis on the relation between visuomotor integration and academic achievement: Role of educational stage and disability
Khatib, L. A., Li, Y., Geary, D. C., & Popov, V. (2021) · Educational Research Review · doi:10.1016/j.edurev.2021.100412 · Cited by 37
Generalization and recovery of post-retrieval amnesia.
Alfei, J. M., Monti, R. I. F., Molina, V. A., Bundel, D. D., Luyten, L., & Beckers, T. (2020) · Journal of Experimental Psychology General · doi:10.1037/xge0000765 · Cited by 21
Aversive memories can be weakened during human sleep via the reactivation of positive interfering memories
Xia, T., Chen, D., Zeng, S., Yao, Z., Liu, J., Qin, S., Paller, K. A., Torres-Platas, S. G., Antony, J. W., & Hu, X. (2024) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2400678121 · Cited by 18
Augmenting exposure therapy with pre-extinction fear memory reactivation and deepened extinction: A randomized controlled trial
Lancaster, C. L., Monfils, M., & Telch, M. J. (2020) · Behaviour Research and Therapy · doi:10.1016/j.brat.2020.103730 · Cited by 18
Honoring the Past, Envisioning the Future: ABCT’s 50th Anniversary Presidential Address
Craske, M. G. (2017) · Behavior Therapy · doi:10.1016/j.beth.2017.05.003 · Cited by 18
Effects of Cannabis on PTSD Recovery: Review of the Literature and Clinical Insights
Bedard‐Gilligan, M. A., Lehinger, E. A., Cornell-Maier, S., Holloway, A., & Zoellner, L. A. (2022) · Current Addiction Reports · doi:10.1007/s40429-022-00414-x · Cited by 18
Impact of a reminder/extinction procedure on threat-conditioned pupil size and skin conductance responsesPreprint
Zimmermann, J., & Bach, D. R. (2020) · Learning & Memory · doi:10.1101/lm.050211.119 · Cited by 15
A virtual reality study on postretrieval extinction of smoking memory reconsolidation in smokers
Zandonai, T., Benvegnù, G., Tommasi, F., Ferrandi, E., Libener, E., Ferraro, S., Maris, B., & Chiamulera, C. (2021) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2021.108317 · Cited by 14
Locus coeruleus input-modulated reactivation of dentate gyrus opioid-withdrawal engrams promotes extinction
Dai, Z., Liu, Y., Nie, L.-N., Chen, W., Xu, X., Li, Y., Zhang, J., Shen, F., Sui, N., & Liang, J. (2022) · Neuropsychopharmacology · doi:10.1038/s41386-022-01477-0 · Cited by 15
Memory Reconsolidation Updating in Substance Addiction: Applications, Mechanisms, and Future Prospects for Clinical Therapeutics
Huang, S., Liu, X., Li, Z., Si, Y., Yang, L., Deng, J., Luo, Y., Xue, Y.-X., & Lü, L. (2024) · Neuroscience Bulletin · doi:10.1007/s12264-024-01294-z · Cited by 15
Boundary conditions of post-retrieval extinction: A direct comparison of low and high partial reinforcement
Kitamura, H., Johnston, P., Johnson, L. R., & Strodl, E. S. (2020) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2020.107285 · Cited by 13
Making Leaps and Hitting Boundaries in Reconsolidation: Overcoming Boundary Conditions to Increase Clinical Translatability of Reconsolidation-based Therapies
Bui, U. T. D., & Milton, A. L. (2023) · Neuroscience · doi:10.1016/j.neuroscience.2023.03.013 · Cited by 13
Causally mapping human threat extinction relevant circuits with depolarizing brain stimulation methods
Webler, R. D., Oathes, D. J., van Rooij, S. J. H., Gewirtz, J. C., Nahas, Z. H., Lissek, S. M., & Widge, A. S. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.105005 · Cited by 14
Preventing the return of fear memories with postretrieval extinction: A human study using a burst of white noise as an aversive stimulus.
Rey, J. F., Gonzalez-Gonzalez, D., & Redondo, J. (2018) · Behavioral Neuroscience · doi:10.1037/bne0000245 · Cited by 13
A review of the phenomenology, aetiology and treatment of animal phobia and insights for biophobia
Norberg, M. M., Visvalingam, S., Stevenson, R. J., & Saluja, S. (2023) · People and Nature · doi:10.1002/pan3.10514 · Cited by 15
Extracellular matrix: a new player in memory maintenance and psychiatric disorders
Bach, D. R., Brown, S. A., Kleim, B., & Tyagarajan, S. K. (2019) · Swiss Medical Weekly · doi:10.4414/smw.2019.20060 · Cited by 11
Reactivation of the Unconditioned Stimulus Inhibits the Return of Fear Independent of Cortisol
Drexler, S. M., Merz, C. J., Lissek, S., Tegenthoff, M., & Wolf, O. T. (2019) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2019.00254 · Cited by 10
Interfering with emotional processing resources upon associative threat memory reactivation does not affect memory retention
Chalkia, A., Vanaken, L., Fonteyne, R., & Beckers, T. (2019) · Scientific Reports · doi:10.1038/s41598-019-40827-9 · Cited by 10
Peripheral Vision in Patients Following Intraocular Lens Implantation: A Systematic Review and Meta-Analysis
Artal, P., Arvaniti, M., Dimou, P., Stavrinos, C., GINIS, H. S., Hervella, L., & Güell, J. L. (2024) · American Journal of Ophthalmology · doi:10.1016/j.ajo.2024.03.016 · Cited by 10
Avoidance Behavior Prevents Modification of Fear Memory During Reconsolidation
Nitta, Y., Takahashi, T., Haitani, T., Sugimori, E., & Kumano, H. (2018) · Psychological Reports · doi:10.1177/0033294118811116 · Cited by 10
Future Research Directions for REBT
David, D. O., Matu, S. A., Podina, I. R., & Predatu, R. (2019) · Springer eBooks · doi:10.1007/978-3-319-93118-0_6 · Cited by 10
The relationship between sleep quality, snoring symptoms, night shift and risk of stroke in Chinese over 40 years old
Zhang, Y., Zhang, T., Xia, X., Hu, Y., Zhang, C., Liu, R., Yang, Y., Li, X., & Yue, W. (2023) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2023.1134187 · Cited by 10
Detrimental Effects of a Retrieval-Extinction Procedure on Nicotine Seeking, but Not Cocaine Seeking
Struik, R. F., Vries, T. J. D., & Peters, J. (2019) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2019.00243 · Cited by 9
Using Extinction-Renewal to Circumvent the Memory Strength Boundary Condition in Fear Memory Reconsolidation
Campbell, T. L., Kochli, D. E., McDaniel, M. A., Myers, M. K., Dunn, M. E., Diana, V. A., & Quinn, J. J. (2021) · Brain Sciences · doi:10.3390/brainsci11081023 · Cited by 8
Investigating the efficacy of the reminder-extinction procedure to disrupt contextual threat memories in humans using immersive Virtual Reality
Houtekamer, M. C., Henckens, M. J. A. G., Mackey, W. E., Dunsmoor, J. E., Homberg, J. R., & Kroes, M. C. W. (2020) · Scientific Reports · doi:10.1038/s41598-020-73139-4 · Cited by 11
Memory Reconsolidation Therapy for Police Officers with Post-traumatic Stress Disorder
Kerswell, N. L., Strodl, E. S., Hawkins, D., & Johnson, L. R. (2020) · Journal of Police and Criminal Psychology · doi:10.1007/s11896-020-09363-5 · Cited by 9
Reconsolidation and Fear Extinction: An Update
Raskin, M., & Monfils, M. (2023) · Current topics in behavioral neurosciences · doi:10.1007/7854_2023_438 · Cited by 9
The influence of dispositional cognitive reappraisal and expressive suppression on post‐retrieval and standard extinction
Kitamura, H., Strodl, E. S., Johnston, P., & Johnson, L. R. (2022) · Psychophysiology · doi:10.1111/psyp.14048 · Cited by 7
Clinical Translation of Memory Reconsolidation Research: Therapeutic Methodology for Transformational Change by Erasing Implicit Emotional Learnings Driving Symptom ProductionPreprint
Ecker, B. (2017) · PsyArXiv (OSF Preprints) · doi:10.31234/osf.io/zrq2m · Cited by 6
Testing the memory reconsolidation hypothesis in a fear extinction paradigm: The effects of ecological and arbitrary stimuli
Dural, S., Gür, E., & Çetınkaya, H. (2022) · Learning & Behavior · doi:10.3758/s13420-022-00536-2 · Cited by 6
Reconsolidation Behavioral Updating of Human Emotional Memory: A Comprehensive Review and Unified Analysis to Identify the Causes of Replication Failures, the Role of Prediction Error, and Optimal Clinical Translation
Ecker, B. (2024) · Journal of Psychiatry and Psychiatric Disorders · doi:10.26502/jppd.2572-519x0226 · Cited by 7
Systematic mapping and bibliometric analysis of meta-analyses on animal cognition
Mizuno, A., Lagisz, M., Pollo, P., Guillette, L. M., Soma, M., & Nakagawa, S. (2025) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2025.106342 · Cited by 5
Carbon Dioxide Reactivity Differentially Predicts Fear Expression After Extinction and Retrieval-Extinction in Rats
Raskin, M., Keller, N. E., Agee, L. A., Shumake, J., Smits, J. A. J., Telch, M. J., Otto, M. W., Lee, H. J., & Monfils, M. (2024) · Biological Psychiatry Global Open Science · doi:10.1016/j.bpsgos.2024.100310 · Cited by 4
Self-citation
Memory Reconsolidation
Nadel, L., & Sederberg, P. B. (2024) · Oxford University Press eBooks · doi:10.1093/oxfordhb/9780190917982.013.44 · Cited by 9
Is it possible to modify fear memories in humans with extinction training within a single day?
Redondo, J., Rey, J. F., & Gonzalez-Gonzalez, D. (2018) · Psychological Research · doi:10.1007/s00426-018-1017-4 · Cited by 4
Persistence and plasticity in the human memory system: An empirical investigation of the overwriting hypothesisPreprint
Hardwicke, T. E. (2017) · Thesis Commons (OSF Preprints) · doi:10.31237/osf.io/r4c32 · Cited by 4

Authors: Kredlow, M. A., Unger, L. D., & Otto, M. W.
Affiliations: Boston University (US)
ORCID: Kredlow, M. Alexandra
Unger, Leslie D.
Otto, Michael W.
Venue: Psychological Bulletin
Publisher: American Psychological Association (APA)
Published: 2016-03
Volume: 142
Issue: 3
Pages: 314-336
ISSN: 0033-2909 (ISSN-L)
1939-1455
DOI: 10.1037/bul0000034
PMC: PMC4760909
OpenAlex: W2406870053
Cited by: 130
References: 107
Citations by year: 2026: 8 · 2025: 4 · 2024: 9 · 2023: 6 · 2022: 12 · 2021: 7 · 2020: 20 · 2019: 17 · 2018: 19 · 2017: 23 · 2016: 5
FWCI: 1.54
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: other-oa
www.apa.org/pubs/journals/resources/open-access.aspx (am, 294 d)
Locations: Psychological Bulletin (publishedVersion, other-oa)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: National Institutes of Health (1F31MH103969)
Topics: Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
Life Sciences › Neuroscience › Cognitive Neuroscience › Memory Processes and Influences
Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
Keywords: memory reconsolidation, return of fear, fear extinction, appetitive memory, fear conditioning, exposure therapy, anxiety disorders, traumatic stress, substance use disorders
MeSH terms: Memory Consolidation, Animals, Appetitive Behavior, Extinction, Psychological, Fear, Humans, Mental Recall

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Harnessing reconsolidation to weaken fear and appetitive memories: A meta-analysis of post-retrieval extinction effects.

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks