The DOI matches its Crossref record.
Repression of lignin biosynthesis promotes cellulose accumulation and growth in transgenic trees
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
No references could be resolved yet.
Research works printed but not linked: 46
- Freudenberg, K. Lignin: its constitution and formation from p-hydroxycinnamyl alcohols. Science 148, 595–600 (1965). · DOI · Paper page
- Whetten, R.W., MacKay, J.J. & Sederoff, R.R. Recent advances in understanding lignin biosynthesis. Annu. Rev. Plant Physiol. Plant Mol. Biol. 49, 585–609 (1998). · DOI · Paper page
- Van Doorsselaere, J. et al. A novel lignin in poplar trees with a reduced caffeic acid/5-hydroxyferulic acid O-methyltransferase activity. Plant J. 8, 855–864 (1995). · DOI · Paper page
- Tsai, C.-J. et al. Suppression of O-methyltransferase gene by homologous sense transgene in quaking aspen causes red-brown wood phenotypes. Plant Physiol. 117, 101–112 (1998). · DOI
- Baucher, M. et al. Red xylem and higher lignin extractability by down-regulating a cinnamyl alcohol dehydrogenase in poplar. Plant Physiol. 112, 1479–1490 (1996). · DOI · Paper page
- Dwivedi, U.N. et al. Modification of lignin biosynthesis in transgenic Nicotiana through expression of an antisense O-methyltransferase gene from Populus. Plant Mol. Biol. 26, 61– 71 (1994). · DOI
- Halpin, C. et al. Manipulation of lignin quality by downregulation of cinnamyl alcohol dehydrogenase. Plant J. 6, 339– 350 (1994). · DOI · Paper page
- Atanassova, R. et al. Altered lignin composition in transgenic tobacco expressing O-methyltransferase sequences in sense and antisense orientation. Plant J. 8, 465–477 ( 1995). · DOI · Paper page
- Hibino, T., Takabe, K., Kawazu, T., Shibata, D. & Higuchi, T. Increase of cinnamaldehyde groups in lignin of transgenic tobacco plants carrying an antisense gene for cinnamyl alcohol dehydrogenase. Biosci. Biotech. Biochem. 59, 929– 931 (1995). · DOI
- Elkind, Y. et al. Abnormal plant development and down-regulation of phenylpropanoid biosynthesis in transgenic tobacco containing a heterologous phenylalanine ammonia-lyase gene. Proc. Natl. Acad. Sci USA 87, 9057–9061 (1990). · DOI · Paper page
- Bate, N. et al. Quantitative relationship between phenylalanine ammonia-lyase levels and phenylpropanoid accumulation in transgenic tobacco identifies a rate-limiting step in natural product synthesis. Proc. Natl. Acad. Sci. USA 91, 7608–7612 ( 1994). · DOI · Paper page
- Kajita, S., Katayama, Y. & Omori, S. Alterations in the biosynthesis of lignin in transgenic plants with chimeric genes for 4-coumarate:coenzyme A ligase. Plant Cell Physiol. 37, 957–965 (1996). · DOI
- Kajita, S., Hishiyama, S., Tomimura, Y., Katayama, Y. & Omori, S. Structural characterization of modified lignin in transgenic tobacco plants in which the activity of 4-coumarate:coenzyme A ligase is depressed. Plant Physiol. 114, 871–879 (1997). · DOI
- Lee, D., Meyer, K., Chapple, C. & Douglas, C.J. Antisense suppression of 4-coumarate:coenzyme A ligase activity in Arabidopsis leads to altered lignin subunit composition. Plant Cell 9, 1985–1998 (1997). · DOI · Paper page
- Piquemal, J. et al. Down-regulation of cinnamoyl-CoA reductase induces significant changes of lignin profiles in transgenic tobacco plants. Plant J. 13, 71–83 ( 1998). · DOI · Paper page
- Hu, W.-J. et al. Compartmentalized expression of two structurally and functionally distinct 4-coumarate:CoA ligase genes in aspen (Populus tremuloides). Proc. Natl. Acad. Sci. USA 95, 5407– 5412 (1998). · DOI · Paper page
- Hakomori, S.I. A rapid permethylation of glycolipids and polysaccharides catalyzed by methylsulfinyl carbanion in dimethyl sulphoxide. J. Biochem. Tokyo 55, 205–208 (1964).
- Ciucanu, I. & Kerek, F. A simple and rapid method for the permethylation of carbohydrates. Carbohydr. Res. 131 , 209–217 (1984). · DOI · Paper page
- Arioli, T. et al. Molecular analysis of cellulose biosynthesis in Arabidopsis . Science 279, 717– 720 (1997). · DOI · Paper page
- Delmer, D.P. Biosynthesis of cellulose. Annu. Rev. Plant Physiol. 38, 259–290 (1987). · DOI · Paper page
- Sewalt, V.J.H. et al. Reduced lignin content and altered lignin composition in transgenic tobacco down-regulated in expression of L-phenylalanine ammonia-lyase or cinnamate 4-hydroxylase. Plant Physiol. 115, 41–50 (1997). · DOI · Paper page
- Tan, K.S., Hoson, T., Masuda, Y. & Kamisaka, S. Effects of ferulic and p-coumaric acids on Oryza coleoptiole growth and the mechanical properties of cell walls. J. Plant Physiol. 140, 460–465 (1992). · doi:10.1016/s0176-1617(11)80825-4
- Mock H.-P. & Strack, D. Energetics of the uridine 5´-diphosphoglucose:hydroxycinnamic acid acyl-glucosyltransferase reaction. Phytochem. 32, 575–579 (1993). · DOI
- Timell, T.E. Compression wood in gymnosperms. (Springer, New York; 1986). · DOI · Paper page
- Pear, J.R., Kawagoe, Y., Schreckengost, W.E., Delmer, D.P. & Stalker, D.M. Higher plants contain homologs of the bacterial celA genes encoding the catalytic subunit of cellulose synthase. Proc. Natl. Acad. Sci. USA 93, 12637–12642 (1996). · DOI · Paper page
- Creelman, R.A. & Mullet, J.E. Oligosaccharins, brassinolides, and jasmonates: nontraditional regulators of plant growth, development, and gene expression. Plant Cell 9, 1211–1223 (1997). · DOI · Paper page
- Logemann, E. et al. Gene activation by UV light, fungal elicitor or fungal infection in Petroselinum crispum is correlated with repression of cell cycle-related genes. Plant J. 8, 865– 876 (1995). · doi:10.1046/j.1365-313x.1995.8060865.x
- Lee, T.T. & Skoog, S. Effects of substituted phenols on bud formation and growth of tobacco tissue cultures Physiol. Plant. 18, 386–402 ( 1965). · doi:10.1111/j.1399-3054.1965.tb06902.x
- Nitsch, J.P. & Nitsch, C. Composes phenolique et croissance vegetale. Ann. Physiol. Veg. 4, 211– 225 (1962).
- Zenk, M.H. & Muller, G.Z. In vivo destruction of exogenously applied indole-acetic acid as influenced by phenolic acids. Nature 200, 761–763 ( 1963). · doi:10.1038/200761a0
- Hahlbrock, K. & Grisebach, H. Enzymic controls in the biosynthesis of lignin and flavonoids. Ann. Rev. Plant Physiol. 30, 105–130 (1979). · doi:10.1146/annurev.pp.30.060179.000541
- Shirley, B.W. Flavonoid biosynthesis: new functions for an old pathway. Trends Plant Sci. 1, 377–382 ( 1996).
- Jacobs, M. & Rubery, P.H. Naturally occurring auxin transport regulators. Science 241, 346– 349 (1988). · DOI · Paper page
- Ruegger, M. et al. Reduced naphthylphthalamic acid binding in the tir3 mutant of Arabidopsis is associated with a reduction in polar auxin transport and diverse morphological defects. Plant Cell 9, 745–757 (1997). · DOI · Paper page
- Tsai, C.-J., Podila, G.K. & Chiang, V.L. Agrobacterium-mediated transformation of quaking aspen (Populus tremuloides) and regeneration of transgenic plants. Plant Cell Rep. 14, 94– 97 (1994).
- Datla, R.S.S., et al. Improved high-level constitutive foreign gene expression in plants using an AMV RNA4 untranslated leader sequence. Plant Sci. 94, 139–149 ( 1993). · DOI
- Bugos, R.C. et al. RNA isolation from plant tissues recalcitrant to extraction in guanidine. Biotechniques 19, 734– 737 (1995).
- Chiang, V.L. & Funaoka, M. The dissolution and condensation reactions of guaiacyl and syringyl units in residual lignin during kraft delignification of sweetgum. Holzforschung 44, 147– 155 (1990). · DOI
- Rolando, C., Monties, B. & Lapierre, C. in Methods in lignin chemistry (eds Lin, S.Y. & Dence, C.W.) 334–349 (Springer, New York; 1992). · DOI · Paper page
- Ralph, J. et al. Pathway of p-coumaric acid incorporation into maize lignin as revealed by NMR. J. Am. Chem. Soc. 116, 9448–9456 (1994). · DOI · Paper page
- Palmer, A.G., Cavanagh, J., Wright, P.E. & Rance, M. Sensitivity improvement in proton-detected two-dimensional heteronuclear correlation NMR spectroscopy. J. Magn. Reson. A 93, 151–170 (1991).
- Braunschweiler, L. & Ernst, R.R. Coherence transfer by isotropic mixing: application to proton correlation spectroscopy. J. Magn. Reson. 53, 521–528 (1983).
- Ruiz-Cabello, J. et al. Gradient-enhanced heteronuclear correlation spectroscopy. Theory and experimental aspects. J. Magn. Reson. 100 , 282–302 (1992).
- Hartley, R.D. Improved methods for the estimation by gas-liquid chromatography of lignin degradation products from plants. Chromatography 54 , 335–344 (1971). · doi:10.1016/s0021-9673(01)80289-2
- Chiang, V.L. & Sarkanen, K.V. Ammonium sulfide organosolv pulping. Wood Sci. Technol. 17, 217– 226 (1983). · doi:10.1007/bf00372320
- Davis, M.W. A rapid modified method for compositional carbohydrate analysis of lignocellulosics by high pH anion-exchange chromatography with pulsed amperometric detection (HPAEC/PAD). J. Wood Chem. Technol. 18, 235–252 (1988). · DOI
Cited by
Boerjan, W., Ralph, J., & Baucher, M. (2003) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.54.031902.134938 · Cited by 4,504
Self-citationProduction of plant secondary metabolites: a historical perspective
Bourgaud, F., Gravot, A., Milesi, S., & Gontier, E. (2001) · Plant Science · doi:10.1016/s0168-9452(01)00490-3 · Cited by 1,251
Cell-wall carbohydrates and their modification as a resource for biofuels
Pauly, M., & Keegstra, K. (2008) · The Plant Journal · doi:10.1111/j.1365-313x.2008.03463.x · Cited by 864
Whole plant cell wall characterization using solution-state 2D NMR
Mansfield, S. D., Kim, H., Lu, F., & Ralph, J. (2012) · Nature Protocols · doi:10.1038/nprot.2012.064 · Cited by 720
Self-citationPlants to power: bioenergy to fuel the future
Yuan, J. S., Tiller, K. H., Al-Ahmad, H., Stewart, N. R., & Stewart, C. N. (2008) · Trends in Plant Science · doi:10.1016/j.tplants.2008.06.001 · Cited by 474
Metadata
- Authors
- Hu, W.-J., Harding, S. A., Lung, J., Popko, J. L., Ralph, J., Stokke, D. D., Tsai, C.-J., & Chiang, V. L.
- Venue
- Nature Biotechnology
- Published
- 1999-08
- Volume
- 17
- Issue
- 8
- Pages
- 808-812
- ISSN
- 0733-222X (ISSN-L)
- 1087-0156
- 1546-1696
- OpenAlex
- W1725214865
- Cited by
- 795
- References
- 0
- FWCI
- 32.58
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Repression of lignin biosynthesis promotes cellulose accumulation and growth in transgenic trees. https://app.cochat.ai/papers/10.1038/11758
- The paper
- Hu, W.-J., Harding, S. A., Lung, J., Popko, J. L., Ralph, J., Stokke, D. D., Tsai, C.-J., & Chiang, V. L. (1999). Repression of lignin biosynthesis promotes cellulose accumulation and growth in transgenic trees. Nature Biotechnology. https://doi.org/10.1038/11758
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.