Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 510

The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

Rab5 regulates motility of early endosomes on microtubules

Nielsen, Erik, Severin, Fedor, Backer, Jonathan M., Hyman, Anthony A., Zerial, Marino·1999·Nature Cell Biology
DOI 10.1038/14075
Open this paper in CoChat — free account

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1038/14075

Cites

4 of 4 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 4 references

Research works printed but not linked: 41

  1. Mellman, I. Endocytosis and molecular sorting. Annu. Rev. Cell Dev. Biol. 12, 575–625 (1996). · DOI · Paper page
  2. Lippincott-Schwartz, J. Cytoskeletal proteins and Golgi dynamics. Curr. Opin. Cell Biol. 10, 52–59 ( 1998). · DOI · Paper page
  3. Matteoni, R. & Kreis, T. E. Translocation and clustering of endosomes and lysosomes depends on microtubules. J. Cell Biol. 105, 1253–1265 ( 1987). · DOI · Paper page
  4. Gruenberg, J., Griffiths, G. & Howell, K. E. Characterization of the early endosome and putative endocytic carrier vesicles in vivo and with an assay of vesicle fusion in vitro. J. Cell Biol. 108, 1301– 1316 (1989). · DOI · Paper page
  5. McGraw, T. E., Dunn, K. W. & Maxfield, F. R. Isolation of a temperature-sensitive variant Chinese hamster ovary cell line with a morphologically altered endocytic recycling compartment. J. Cell Physiol. 155, 579– 594 (1993). · DOI
  6. Aniento, F., Emans, N., Griffiths, G. & Gruenberg, J. Cytoplasmic dynein-dependent vesicular transport from early to late endosomes. J. Cell Biol. 123, 1373–1387 (1993). · DOI · Paper page
  7. Bomsel, M., Parton, R., Kuznetsov, S. A., Schroer, T. & Gruenberg, J. Microtubule- and motor-dependent fusion in vitro between apical and basolateral endocytic vesicles from MDCK cells. Cell 62, 719– 731 (1990). · DOI · Paper page
  8. Riezman, H. Yeast endocytosis. Trends Cell Biol. 3, 273–277 (1993). · DOI
  9. Lamaze, C., Fujimoto, L. M., Yin, H. L. & Schmid, S. L. The actin cytoskeleton is required for receptor-mediated endocytosis in mammalian cells. J. Biol. Chem. 272, 20332– 20335 (1997). · DOI · Paper page
  10. Murphy, C. et al. Endosome dynamics regulated by a Rho protein. Nature 384, 427–432 ( 1996). · DOI · Paper page
  11. Novick, P. & Brennwald, P. Friends and family: the role of the Rab GTPases in vesicular transport. Cell 75, 597–601 (1993). · DOI · Paper page
  12. Simonsen, A. et al. EEA1 links phosphatidylinositol 3-kinase function to Rab5 regulation of endosome fusion. Nature 394, 494–498 (1998). · DOI · Paper page
  13. TerBush, D. R., Maurice, T., Roth, D. & Novick, P. The Exocyst is a multiprotein complex required for exocytosis in Saccharomyces cerevisiae . EMBO J. 15, 6483–6494 (1996). · DOI · Paper page
  14. Novick, P. & Zerial, M. The diversity of Rab proteins in vesicle transport. Curr. Opin. Cell Biol. 9, 496–504 (1997). · DOI · Paper page
  15. Bucci, C. et al. The small GTPase rab5 functions as a regulatory factor in the early endocytic pathway. Cell 70, 715– 728 (1992). · DOI · Paper page
  16. Stenmark, H. et al. Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis. EMBO J. 13, 1287– 1296 (1994). · DOI · Paper page
  17. D"Arrigo, A., Bucci, C., Toh, B. H. & Stenmark, H. Microtubules are involved in bafilomycin A1-induced tubulation and Rab5-dependent vacuolation of early endosomes. Eur. J. Cell Biol. 72, 95–103 (1997).
  18. Scheel, J. & Kreis, T. E. Motor protein independent binding of endocytic carrier vesicles to microtubules in vitro. J. Biol. Chem. 266, 18141–18148 (1991). · DOI
  19. Ullrich, O., Horiuchi, H., Bucci, C. & Zerial, M. Membrane association of Rab5 mediated by GDP-dissociation inhibitor and accompanied by GDP/GTP exchange. Nature 368, 157– 160 (1994). · DOI · Paper page
  20. Howard, J. & Hyman, A. A. Preparation of marked microtubules for the assay of the polarity of microtubule-based motors by fluorescence microscopy. Methods Cell Biol 39, 105– 113 (1993). · DOI
  21. Rybin, V. et al. GTPase activity of rab5 acts as a timer for endocytic membrane fusion. Nature 383, 266– 269 (1996). · DOI · Paper page
  22. Barnard, R. J. O., Morgan, A. & Burgoyne, R. D. Stimulation of NSF ATPase activity by alpha-SNAP is required for SNARE complex disassembly and exocytosis. J. Cell Biol. 139, 875–883 ( 1997). · DOI
  23. Blocker, A. et al. Molecular requirements for bi-directional movement of phagosomes along microtubules. J. Cell Biol. 137, 113 –129 (1997). · DOI
  24. Marlowe, K. J. et al. Changes in kinesin distribution and phosphorylation occur during regulated secretion in pancreatic acinar cells. Eur. J. Cell Biol. 75, 140–152 ( 1998). · DOI
  25. Bi, G. Q. et al. Kinesin- and myosin-driven steps of vesicle recruitment for Ca2+-regulated exocytosis. J. Cell Biol. 138, 999–1008 (1997). · DOI · Paper page
  26. Patki, V. V. J., Lane, W. S., Toh, B. H., Shpetner, H. S. & Corvera, S. Identification of an early endosomal protein regulated by phosphatidylinositol 3-kinase. Proc. Natl Acad. Sci. USA 94, 7326–7330 (1997). · DOI · Paper page
  27. Christoforidis, S. et al. Phosphatidylinositol-3-OH kinases are Rab5 effectors. Nature Cell Biol. 1, 249–252 (1999). · DOI · Paper page
  28. Siddhanta, U., McIlroy, J., Shah, A., Zhang, Y. & Backer, J. M. Distinct roles for the p110alpha and hVPS34 phosphatidylinositol 3"-kinases in vesicular trafficking, regulation of the actin cytoskeleton, and mitogenesis. J. Cell Biol. 143, 1647 –1659 (1998). · DOI
  29. Goodson, H. V., Valetti, C. & Kreis, T. E. Motors and membrane traffic. Curr. Opin. Cell Biol. 9, 18–28 ( 1997). · DOI
  30. Echard, A. et al. Interaction of a Golgi-associated kinesin-like protein with Rab6. Science 279, 580– 585 (1998). · DOI · Paper page
  31. Burkhardt, J. K., Echeverri, C. J., Nilsson, T. & Vallee, R. B. Overexpression of the dynamitin (p50) subunit of the dynactin complex disrupts dynein-dependent maintenance of membrane organelle distribution. J. Cell Biol. 139, 469–484 (1997). · DOI · Paper page
  32. Ferhat, L., Kuriyama, R., Lyons, G. E., Micales, B. & Baas, P. W. Expression of the mitotic motor protein CHO1/MKLP1 in postmitotic neurons. Eur. J. Neurosci. 10, 1383–1393 (1998). · DOI
  33. Saito, N. et al. KIFC2 is a novel neuron-specific C-terminal type kinesin superfamily motor for dendritic transport of multivesicular body-like organelles. Neuron 18, 425–438 ( 1997). · DOI
  34. Hoang, E., Bost-usinger, L. & Burnside, B. Characterization of a novel C-kinesin (KIFC3) abundantly expressed in vertebrate retina and RPE. Exp. Eye Res. 69, 57–68 (1999). · DOI
  35. Shpetner, H., Joly, M., Hartley, D. & Corvera, S. Potential sites of PI-3 kinase function in the endocytic pathway revealed by the PI-3 kinase inhibitor, wortmannin. J. Cell Biol. 132, 595–605 (1996). · DOI
  36. Burd, C. G. & Emr, S. D. Phosphatidylinositol(3)-phosphate signaling mediated by specific binding to RING FYVE domains. Mol. Cell 2, 157–162 ( 1998). · DOI · Paper page
  37. Stenmark, H., Aasland, R., Toh, B. H. & D’Arringo, A. Endosomal localization of the autoantigen EEA1 is mediated by zinc-binding FYVE finger . J. Biol. Chem. 271, 24048– 24054 (1996). · DOI · Paper page
  38. Gorvel, J.-P., Chavrier, P., Zerial, M. & Gruenberg, J. Rab5 controls early endosome fusion in vitro. Cell 64, 915–925 (1991). · DOI · Paper page
  39. Keown, W. A., Campbell, C. R. & Kucherlapati, R. S. Methods for introducing DNA into mammalian cells . Methods Enzymol. 185, 527– 537 (1990). · doi:10.1016/0076-6879(90)85043-n
  40. Horiuchi, H. et al. A novel Rab5 GDP/GTP exchange factor complexed to Rabaptin-5 links nucleotide exchange to effector recruitment and function. Cell 90, 1149–1159 ( 1997). · DOI · Paper page
  41. Bornens, M. & Moudjou, M. Studying the composition and function of centrosomes in vertebrates. Methods Cell Biol. 61 , 13–34 (1999). · DOI

Cited by

See all 510

Metadata

Authors
Nielsen, E., Severin, F., Backer, J. M., Hyman, A. A., & Zerial, M.
Venue
Nature Cell Biology
Publisher
Springer Science and Business Media LLC
Published
1999-09-16
Volume
1
Issue
6
Pages
376-382
ISSN
  • 1465-7392 (ISSN-L)
  • 1476-4679
DOI
10.1038/14075
OpenAlex
W2116422958
Cited by
510
References
4
FWCI
10.46
Type
journal article
Language
en
Open access
closed
Licence
www.springer.com/tdm (tdm)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: Rab5 regulates motility of early endosomes on microtubules. https://app.cochat.ai/papers/10.1038/14075
The paper
Nielsen, E., Severin, F., Backer, J. M., Hyman, A. A., & Zerial, M. (1999). Rab5 regulates motility of early endosomes on microtubules. Nature Cell Biology. https://doi.org/10.1038/14075

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.