Towards a Theoretical Biology
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Each is checked against this paper’s own text: does it say what the citing paper says it does?
Epigenetics is one of the key biological mechanisms mediating the effects of the exposome on aging.
“One of the key biological mechanisms mediating the effects of the exposome on aging is epigenetics, which refers to modifications that alter gene expression without altering the DNA sequence [9].”
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The extended evolutionary synthesis: its structure, assumptions and predictions
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Systems genetics approaches to understand complex traits
Civelek, M., & Lusis, A. J. (2014) · Nature Reviews Genetics · doi:10.1038/nrg3575 · Cited by 621 · see citing works
A new biology for a new century
Woese, C. R. (2004) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.68.2.173-186.2004 · Cited by 641 · see citing works
Epigenetics of the depressed brain: role of histone acetylation and methylation
Sun, H., Kennedy, P. J., & Nestler, E. J. (2013) · Neuropsychopharmacology · doi:10.1038/npp.2012.73 · Cited by 413 · see citing works
Dynamic and linguistic modes of complex systems
PATTEE, H. H. (1977) · International Journal of General Systems · doi:10.1080/03081077708934771 · Cited by 273 · see citing works
The physics of symbols: bridging the epistemic cut
Pattee, H. H. (2001) · Biosystems · doi:10.1016/s0303-2647(01)00104-6 · Cited by 210 · see citing works
Interplay between Epigenetics and Genetics in Cancer
Choi, J. D., & Lee, J.-S. (2013) · Genomics & Informatics · doi:10.5808/gi.2013.11.4.164 · Cited by 131 · see citing works
Jaeger, J., Irons, D., & Monk, N. (2008) · Development · doi:10.1242/dev.018697 · Cited by 110 · see citing works
Enabling conditions for ‘open-ended evolution’
Ruiz-Mirazo, K., Umerez, J., & Moreno, A. (2007) · Biology & Philosophy · doi:10.1007/s10539-007-9076-8 · Cited by 72 · see citing works
Nolfi, S., Bongard, J., Husbands, P., & Floreano, D. (2016) · Springer Handbooks · doi:10.1007/978-3-319-32552-1_76 · Cited by 68 · see citing works
Evolution with material symbol systems
Rocha, L. M. (2001) · Biosystems · doi:10.1016/s0303-2647(01)00110-1 · Cited by 46 · see citing works
THE NATURE OF HIERARCHICAL CONTROLS IN LIVING MATTER
Pattee, H. H. (1972) · Foundations of Mathematical Biology · doi:10.1016/b978-0-12-597201-7.50008-5 · Cited by 43 · see citing works
Aliberti, S. M., & Capunzo, M. (2025) · Nutrients · doi:10.3390/nu17040722 · Cited by 29 · see citing works
- Authors
- WADDINGTON, C. H.
- Corresponding author
- WADDINGTON, C. H.
- Venue
- Nature
- Published
- 1968-05
- Volume
- 218
- Issue
- 5141
- Pages
- 525-527
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W2093905028
- Cited by
- 1,061
- References
- 0
- Citations by year
- 2026: 4 · 2025: 16 · 2024: 20 · 2023: 27 · 2022: 57 · 2021: 24 · 2020: 32 · 2019: 31 · 2018: 20 · 2017: 19 · 2016: 24 · 2015: 23 · 2014: 20 · 2013: 28 · 2012: 35
- FWCI
- 145.69
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Arts and Humanities › History and Philosophy of Science › Philosophy and History of Science
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Evolution and Genetic Dynamics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gene Regulatory Network Analysis
- Keywords
- theoretical biology, mathematical biology, biology, International Union of Biological Sciences
- MeSH terms
- Biology, Mathematics
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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