Moderate loss of function of cyclic-AMP-modulated KCNQ2/KCNQ3 K+ channels causes epilepsy

Coassembly of KVLQT1 and minK (IsK) proteins to form cardiac IKS potassium channel

Sanguinetti, M. C., Curran, M. E., Zou, A., Shen, J., Specter, P. S., Atkinson, D. L., & Keating, M. T. (1996) · Nature · doi:10.1038/384080a0 · Cited by 1,764

Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias

Wang, Q., Curran, M. E., Splawski, I., Burn, T. C., Millholland, J. M., VanRaay, T. J., Shen, J., Timothy, K. W., Vincent, G. M., de Jager, T., et al. (1996) · Nature Genetics · doi:10.1038/ng0196-17 · Cited by 1,759

KvLQT1 and IsK (minK) proteins associate to form the IKS cardiac potassium current

Barhanin, J., Lesage, F., Guillemare, E., Fink, M., Lazdunski, M., & Romey, G. (1996) · Nature · doi:10.1038/384078a0 · Cited by 1,614

A novel potassium channel gene, KCNQ2, is mutated in an inherited epilepsy of newborns

Singh, N. A., Charlier, C., Stauffer, D., DuPont, B. R., Leach, R. J., Melis, R., Ronen, G. M., Bjerre, I., Quattlebaum, T., Murphy, J. V., et al. (1998) · Nature Genetics · doi:10.1038/ng0198-25 · Cited by 1,199

The I.M.A.G.E. Consortium: An Integrated Molecular Analysis of Genomes and Their Expression

Lennon, G., Auffray, C., Polymeropoulos, M., & Soares, M. B. (1996) · Genomics · doi:10.1006/geno.1996.0177 · Cited by 1,123

A Potassium Channel Mutation in Neonatal Human Epilepsy

Biervert, C., Schroeder, B. C., Kubisch, C., Berkovic, S. F., Propping, P., Jentsch, T. J., & Steinlein, O. K. (1998) · Science · doi:10.1126/science.279.5349.403 · Cited by 1,073

A pore mutation in a novel KQT-like potassium channel gene in an idiopathic epilepsy family

Charlier, C., Singh, N. A., Ryan, S. G., Lewis, T. B., Reus, B. E., Leach, R. J., & Leppert, M. (1998) · Nature Genetics · doi:10.1038/ng0198-53 · Cited by 937

Evidence for the formation of heteromultimeric potassium channels in Xenopus oocytes

Isacoff, E. Y., Jan, Y. N., & Jan, L. Y. (1990) · Nature · doi:10.1038/345530a0 · Cited by 461

Heteromultimeric channels formed by rat brain potassium-channel proteins

Ruppersberg, J. P., Schröter, K. H., Sakmann, B., Stocker, M., Sewing, S., & Pongs, O. (1990) · Nature · doi:10.1038/345535a0 · Cited by 409

Benign familial neonatal convulsions linked to genetic markers on chromosome 20

Leppert, M., Anderson, V. E., Quattlebaum, T., Stauffer, D., O'Connell, P., Nakamura, Y., Lalouel, J.-M., & White, R. (1989) · Nature · doi:10.1038/337647a0 · Cited by 366

Properties of KvLQT1 K+ channel mutations in Romano-Ward and Jervell and Lange-Nielsen inherited cardiac arrhythmias

Chouabe, C. (1997) · The EMBO Journal · doi:10.1093/emboj/16.17.5472 · Cited by 280

Molecular dissection of gating in the ClC-2 chloride channel

Jordt, S.-E. (1997) · The EMBO Journal · doi:10.1093/emboj/16.7.1582 · Cited by 258

Heteropolymeric potassium channels expressed in xenopus oocytes from cloned subunits

Christie, M. J., North, R. A., Osborne, P. B., Douglass, J., & Adelman, J. P. (1990) · Neuron · doi:10.1016/0896-6273(90)90052-h · Cited by 249

Heteromultimeric CLC chloride channels with novel properties

Lorenz, C., Pusch, M., & Jentsch, T. J. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.23.13362 · Cited by 247

Genetic heterogeneity in benign familial neonatal convulsions: identification of a new locus on chromosome 8q.

Lewis, T. B., Leach, R. J., Ward, K. J., O'Connell, P., & Ryan, S. G. (1993) · PubMed · Cited by 194

Pathophysiological Mechanisms of Dominant and Recessive KvLQT1 K+ Channel Mutations Found in Inherited Cardiac Arrhythmias

Wollnik, B., Schroeder, B. C., Kubisch, C., Esperer, H. D., Wieacker, P., & Jentsch, T. J. (1997) · Human Molecular Genetics · doi:10.1093/hmg/6.11.1943 · Cited by 189

KVLQT1 mutations in three families with familial or sporadic long QT syndrome

Russell, M. W. W. (1996) · Human Molecular Genetics · doi:10.1093/hmg/5.9.1319 · Cited by 80

Neuronal KCNQ potassium channels:physislogy and role in disease

Jentsch, T. J. (2000) · Nature Reviews Neuroscience · doi:10.1038/35036198 · Cited by 849

Pathways modulating neural KCNQ/M (Kv7) potassium channels

Delmas, P., & Brown, D. A. (2005) · Nature Reviews Neuroscience · doi:10.1038/nrn1785 · Cited by 686

A Common Ankyrin-G-Based Mechanism Retains KCNQ and NaVChannels at Electrically Active Domains of the Axon

Pan, Z., Kao, T., Horvath, Z., Lemos, J., Sul, J.-Y., Cranstoun, S. D., Bennett, V., Scherer, S. S., & Cooper, E. C. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.4314-05.2006 · Cited by 585

Neuromodulation of thought: flexibilities and vulnerabilities in prefrontal cortical network synapses

Arnsten, A. F. T., Wang, M. J., & Paspalas, C. D. (2012) · Neuron · doi:10.1016/j.neuron.2012.08.038 · Cited by 538

PIP2 Activates KCNQ Channels, and Its Hydrolysis Underlies Receptor-Mediated Inhibition of M Currents

Zhang, H., Craciun, L. C., Mirshahi, T., Rohács, T., Lopes, C. M. B., Jin, T., & Logothetis, D. E. (2003) · Neuron · doi:10.1016/s0896-6273(03)00125-9 · Cited by 523