Cited by 583Sleep and Wakefulness ResearchVisual perception and processing mechanismsNeural dynamics and brain function

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Effects of sleep and arousal on the processing of visual information in the cat

Livingstone, Margaret S., Hubel, David H.·1981·Nature

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Abstract

Single units in the cat lateral geniculate nucleus and primary visual cortex show changes in both spontaneous and visually evoked firing as a function of the state of wakefulness. On arousal spontaneous firing is smoother and often reduced, whereas evoked responses are usually enhanced; the result is an increase in the signal-to-noise ratio. Single- and double-label 2-deoxyglucose autoradiographs show further that slow-wave sleep differentially depresses visually evoked activity in the deeper layers of the visual cortex.

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“Introduction Arousal profoundly impacts brain activity, at both local and global scales (Livingstone and Hubel, 1981; Marrocco et al., 1994; Cantero et al., 1999; Gould et al., 2011; Grent’t-Jong et al., 2011; Stringer et al., 2019), and affects sensory perception by tailoring sensory processing to match behavioral de…”
Background

Authors: Livingstone, M. S., & Hubel, D. H.
Affiliations: Harvard University (US)
ORCID: Livingstone, Margaret S.
Venue: Nature
Publisher: Springer Science and Business Media LLC
Published: 1981-06
Volume: 291
Issue: 5816
Pages: 554-561
ISSN: 0028-0836 (ISSN-L)
1476-4687
DOI: 10.1038/291554a0
OpenAlex: W2029325913
Cited by: 583
References: 41
Citations by year: 2026: 6 · 2025: 5 · 2024: 15 · 2023: 9 · 2022: 6 · 2021: 5 · 2020: 6 · 2019: 8 · 2018: 5 · 2017: 12 · 2016: 12 · 2015: 18 · 2014: 9 · 2013: 12 · 2012: 5
FWCI: 10.34
Type: journal article
Language: en
Open access: closed
Licence: www.springer.com/tdm (tdm)
Locations: Nature (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (5r01ns007848-19, 5r01ey000605-43)
Topics: Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
Keywords: sleep, arousal, visual processing, lateral geniculate nucleus, primary visual cortex, single-unit activity, spontaneous firing, visual evoked potentials, signal-to-noise ratio, slow-wave sleep, 2-deoxyglucose autoradiography, cats
MeSH terms: Action Potentials, Animals, Arousal, Autoradiography, Axonal Transport, Carbon Radioisotopes, Cats, Deoxyglucose, Evoked Potentials, Geniculate Bodies, Sleep, Tritium, Vision, Ocular, Visual Cortex, Visual Perception

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Effects of sleep and arousal on the processing of visual information in the cat

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