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Overproduction of p53 antigen makes established cells highly tumorigenic
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“TP53 was initially thought to be an oncogene, and high levels of p53 conferred significant tumorigenic potential to rat embryonic fibroblasts.16,17”
From Targeting p53 pathways: mechanisms, structures, and advances in therapy (2023) · cites this paper as [17]
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Research works printed but not linked: 22
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Cited by
Momand, J., Zambetti, G. P., Olson, D. C., George, D., & Levine, A. J. (1992) · Cell · doi:10.1016/0092-8674(92)90644-r · Cited by 3,113
The p53 proto-oncogene can act as a suppressor of transformation
Finlay, C. A., Hinds, P. W., & Levine, A. J. (1989) · Cell · doi:10.1016/0092-8674(89)90045-7 · Cited by 1,987
The first 30 years of p53: growing ever more complex.
Levine, A. J., & Oren, M. (2009) · Nature Reviews Cancer · doi:10.1038/nrc2723 · Cited by 1,967
Self-citationTargeting p53 pathways: mechanisms, structures, and advances in therapy
Wang, H., Guo, M., Wei, H., & Chen, Y. (2023) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-023-01347-1 · Cited by 1,016
Gain of function mutations in p53
Dittmer, D., Pati, S., Zambetti, G., Chu, S., Teresky, A. K., Moore, M., Finlay, C., & Levine, A. J. (1993) · Nature Genetics · doi:10.1038/ng0593-42 · Cited by 894
Metadata
- Authors
- Eliyahu, D., Michalovitz, D., & Oren, M.
- Venue
- Nature
- Published
- 1985-07
- Volume
- 316
- Issue
- 6024
- Pages
- 158-160
- ISSN
- 0028-0836
- 1476-4687
- Cited by
- 146
- References
- 0
- Language
- en
- Licence
- www.springer.com/tdm (tdm)
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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- CoChat. (2026). Citation check: Overproduction of p53 antigen makes established cells highly tumorigenic. https://app.cochat.ai/papers/10.1038/316158a0
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- Eliyahu, D., Michalovitz, D., & Oren, M. (1985). Overproduction of p53 antigen makes established cells highly tumorigenic. Nature. https://doi.org/10.1038/316158a0
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.