Glycosyltransferase activity of Fringe modulates Notch–Delta interactions

The Notch1 receptor is cleaved constitutively by a furin-like convertase

Logeat, F., Chable-Bessia, C., Brou, C., Bail, O. L., Jarriault, S., Seidah, N. G., & Israël, A. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.14.8108 · Cited by 737 · see citing works

Intracellular Cleavage of Notch Leads to a Heterodimeric Receptor on the Plasma Membrane

Blaumueller, C. M., Qi, H., Zagouras, P., et al. (1997) · Cell · doi:10.1016/s0092-8674(00)80336-0 · Cited by 616 · see citing works

Fringe modulates Notch–ligand interactions

Panin, V. M., Papayannopoulos, V., Wilson, R., & Irvine, K. D. (1997) · Nature · doi:10.1038/43191 · Cited by 587 · see citing works

Defects in somite formation in lunatic fringe-deficient mice

Zhang, N., & Gridley, T. (1998) · Nature · doi:10.1038/28625 · Cited by 405 · see citing works

Serrate signals through Notch to establish a Wingless-dependent organizer at the dorsal/ventral compartment boundary of the Drosophila wing

Díaz‐Benjumea, F. J., & Cohen, S. M. (1995) · Development · doi:10.1242/dev.121.12.4215 · Cited by 403 · see citing works

lunatic fringe is an essential mediator of somite segmentation and patterning

Evrard, Y. A., Lun, Y., Aulehla, A., Gan, L., & Johnson, R. L. (1998) · Nature · doi:10.1038/28632 · Cited by 392 · see citing works

EphrinB Ligands Recruit GRIP Family PDZ Adaptor Proteins into Raft Membrane Microdomains

Brückner, K., Labrador, J.-P., Scheiffele, P., Herb, A., Seeburg, P. H., & Klein, R. (1999) · Neuron · doi:10.1016/s0896-6273(00)80706-0 · Cited by 342 · see citing works

fringe, a boundary-specific signaling molecule, mediates interactions between dorsal and ventral cells during Drosophila wing development

Irvine, K. D., & Wieschaus, E. F. (1994) · Cell · doi:10.1016/0092-8674(94)90545-2 · Cited by 341 · see citing works

Delta is a ventral to dorsal signal complementary to Serrate, another Notch ligand, in Drosophila wing formation.Preprint

Doherty, D., Feger, G., Younger, S. H., Jan, L. Y., & Jan, Y. N. (1996) · Genes & Development · doi:10.1101/gad.10.4.421 · Cited by 320 · see citing works

Activation and function of Notch at the dorsal-ventral boundary of the wing imaginal disc

de Celis, J. F., Garcı́a-Bellido, A., & Bray, S. J. (1996) · Development · doi:10.1242/dev.122.1.359 · Cited by 315 · see citing works

Identification and characterization of large galactosyltransferase gene families: galactosyltransferases for all functions

Amado, M., Almeida, R., Schwientek, T., & Clausen, H. (1999) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/s0304-4165(99)00168-3 · Cited by 300 · see citing works

A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway

Johnston, S. H., Rauskolb, C., Wilson, R., Prabhakaran, B., Irvine, K. D., & Vogt, T. (1997) · Development · doi:10.1242/dev.124.11.2245 · Cited by 294 · see citing works

Crystal structures of the bovine β4galactosyltransferase catalytic domain and its complex with uridine diphosphogalactose

Gastinel, L. N., Cambillau, C., & Bourne, Y. (1999) · The EMBO Journal · doi:10.1093/emboj/18.13.3546 · Cited by 274 · see citing works

Expression of Radical fringe in limb-bud ectoderm regulates apical ectodermal ridge formation

Laufer, E., Dahn, R. D., Orozco, O. E., et al. (1997) · Nature · doi:10.1038/386366a0 · Cited by 267 · see citing works

Cell recognition, signal induction, and symmetrical gene activation at the dorsal-ventral boundary of the developing drosophila wing

Kim, J., Irvine, K. D., & Carroll, S. B. (1995) · Cell · doi:10.1016/0092-8674(95)90476-x · Cited by 262 · see citing works

O-Linked fucose and other post-translational modifications unique to EGF modules

Harris, R. J., & Spellman, M. W. (1993) · Glycobiology · doi:10.1093/glycob/3.3.219 · Cited by 261 · see citing works

Serrate-mediated activation of Notch is specifically blocked by the product of the gene fringe in the dorsal compartment of the Drosophila wing imaginal disc

Fleming, R. J., Gu, Y., & Hukriede, N. A. (1997) · Development · doi:10.1242/dev.124.15.2973 · Cited by 259 · see citing works

Retention and retrieval in the endoplasmic reticulum and the Golgi apparatus

Nilsson, T., & Warren, G. W. (1994) · Current Opinion in Cell Biology · doi:10.1016/0955-0674(94)90070-1 · Cited by 247 · see citing works

Localization of three human polypeptide GalNAc-transferases in HeLa cells suggests initiation of O-linked glycosylation throughout the Golgi apparatus

Röttger, S., White, J., Wandall, H. H., Olivo, J.-C., Stark, A., Bennett, E. P., Whitehouse, C., Berger, E. G., Clausen, H., & Nilsson, T. (1998) · Journal of Cell Science · doi:10.1242/jcs.111.1.45 · Cited by 239 · see citing works

Notch regulates wingless expression and is not required for reception of the paracrine wingless signal during wing margin neurogenesis in Drosophila

Rulifson, E. J., & Blair, S. S. (1995) · Development · doi:10.1242/dev.121.9.2813 · Cited by 204 · see citing works

Radical fringe positions the apical ectodermal ridge at the dorsoventral boundary of the vertebrate limb

Rodrı́guez-Esteban, C., Schwabe, J. W. R., Peña, J. D. L., et al. (1997) · Nature · doi:10.1038/386360a0 · Cited by 198 · see citing works

Structure/function studies of glycosyltransferases

Breton, C., & Imberty, A. (1999) · Current Opinion in Structural Biology · doi:10.1016/s0959-440x(99)00006-8 · Cited by 195 · see citing works

Fringe, Notch, and making developmental boundaries

Irvine, K. D. (1999) · Current Opinion in Genetics & Development · doi:10.1016/s0959-437x(99)80066-5 · Cited by 191 · see citing works

A Family of Human β3-Galactosyltransferases

Amado, M., Almeida, R., Carneiro, F., Levery, S. B., Holmes, E. H., Nomoto, M., Hollingsworth, M. A., Hassan, H., Schwientek, T., Nielsen, P. A., et al. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.21.12770 · Cited by 191 · see citing works

ELF-2, a New Member of the Eph Ligand Family, Is Segmentally Expressed in Mouse Embryos in the Region of the Hindbrain and Newly Forming Somites

Bergemann, A. D., Cheng, H.-J., Brambilla, R., Klein, R., & Flanagan, J. G. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.9.4921 · Cited by 151 · see citing works

Secreted Fringe-like Signaling Molecules May Be Glycosyltransferases

Yuan, Y. P., Schultz, J., Mlodzik, M., & Peer Bork, B. (1997) · Cell · doi:10.1016/s0092-8674(00)81852-8 · Cited by 110 · see citing works

The mechanism of Golgi segregation during mitosis is cell type-specific

Stanley, H. A., Botas, J., & Malhotra, V. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.26.14467 · Cited by 100 · see citing works

The Secreted Product of Xenopus Gene lunatic Fringe , a Vertebrate Signaling Molecule

Wu, J. Y., Wen, L., Zhang, W.-J., & Rao, Y. (1996) · Science · doi:10.1126/science.273.5273.355 · Cited by 58 · see citing works

The O-linked fucose glycosylation pathway: identification and characterization of a uridine diphosphoglucose: fucose-beta1,3- glucosyltransferase activity from Chinese hamster ovary cells

Moloney, D. J. (1999) · Glycobiology · doi:10.1093/glycob/9.7.679 · Cited by 51 · see citing works

Biological roles of glycans

Varki, A. (2017) · Glycobiology · doi:10.1093/glycob/cww086 · Cited by 2,635 · see citing works

Notch signalling: a simple pathway becomes complex

Bray, S. J. (2006) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2009 · Cited by 2,620 · see citing works

Role of Glycosylation in Development

Haltiwanger, R. S., & Lowe, J. B. (2004) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.73.011303.074043 · Cited by 757 · see citing works

Regulation of Notch Signaling by O-Linked Fucose

Okajima, T., & Irvine, K. D. (2002) · Cell · doi:10.1016/s0092-8674(02)01114-5 · Cited by 386 · see citing works

Protein <i>O</i> -fucosyltransferase 1 is an essential component of Notch signaling pathways

Shi, S., & Stanley, P. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0831126100 · Cited by 381 · see citing works

Rumi Is a CAP10 Domain Glycosyltransferase that Modifies Notch and Is Required for Notch Signaling

Acar, M., Jafar-Nejad, H., Takeuchi, H., Rajan, A., Ibrani, D., Rana, N. A., Pan, H., Haltiwanger, R. S., & Bellen, H. J. (2008) · Cell · doi:10.1016/j.cell.2007.12.016 · Cited by 306 · see citing works

Site-specific protein O-glycosylation modulates proprotein processing — Deciphering specific functions of the large polypeptide GalNAc-transferase gene family

Schjoldager, K. T.-B. G., & Clausen, H. (2012) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2012.09.014 · Cited by 193 · see citing works

Functional Conservation of Subfamilies of Putative UDP-N-acetylgalactosamine:Polypeptide N-Acetylgalactosaminyltransferases inDrosophila, Caenorhabditis elegans, and Mammals

Schwientek, T., Bennett, E. P., Flores, C., Thacker, J., Hollmann, M., Reis, C. A., Behrens, J., Mandel, U., Keck, B., Schäfer, M. A., et al. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m202684200 · Cited by 181 · see citing works

Significance of glycosylation in Notch signaling

Takeuchi, H., & Haltiwanger, R. S. (2014) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2014.05.115 · Cited by 166 · see citing works

Differential glycosylation regulates processing of lipoprotein receptors by γ-secretase

May, P., Bock, H. H., Nimpf, J., & Herz, J. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m305858200 · Cited by 142 · see citing works

Roles of Glycosylation in Notch Signaling

(2010) · Current Topics in Developmental Biology · doi:10.1016/s0070-2153(10)92004-8 · Cited by 136 · see citing works

Mesenchymal stem cell infusion therapy in a carbon tetrachloride‐induced liver fibrosis model affects matrix metalloproteinase expression

Rabani, V., Shahsavani, M., Gharavi, M., Piryaei, A., Azhdari, Z., & Baharvand, H. (2010) · Cell Biology International · doi:10.1042/cbi20090386 · Cited by 112 · see citing works

FOXO/Fringe is necessary for maintenance of the germline stem cell niche in response to insulin insufficiency

Yang, S.-A., Wang, W.-D., Chen, C.-T., Tseng, C.-Y., Chen, Y.-N., & Hsu, H.-J. (2013) · Developmental Biology · doi:10.1016/j.ydbio.2013.07.018 · Cited by 37 · see citing works

Differential requirements for the neurogenic gene <i>almondex</i> during <i>Drosophila melanogaster</i> development

Michellod, M., Forquignon, F., Santamaria, P., & Randsholt, N. B. (2003) · genesis · doi:10.1002/gene.10233 · Cited by 17 · see citing works

The Notch proteins

Nye, J. S. (1999) · Current Biology · doi:10.1016/s0960-9822(99)80076-1 · Cited by 7 · see citing works

Roles of Glycosylation in Notch Signaling

(2010) · Current Topics in Developmental Biology · doi:10.1016/s0070-2153(10)92004-8 · Cited by 136 · see citing works

The Ins and Outs of Notch Signaling

Weinmaster, G. (1997) · Molecular and Cellular Neuroscience · doi:10.1006/mcne.1997.0612 · Cited by 382 · see citing works

Regulation of Notch Endosomal Sorting and Signaling by Drosophila Nedd4 Family Proteins

Wilkin, M. B., Carbery, A.-M., Fostier, M., Aslam, H., Mazaleyrat, S., Higgs, J. E., Myat, A., Evans, D. A. P., Cornell, M. J., & Baron, M. (2004) · Current Biology · doi:10.1016/j.cub.2004.11.030 · Cited by 190 · see citing works

Inhibition of Notch signalling using fucose analogs

Hao, H., Liu, Z., Wu, P., et al. (2020) · The FASEB Journal · doi:10.1096/fasebj.2020.34.s1.04106