A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity

Weggen, Sascha, Eriksen, Jason L., Das, Pritam, Sagi, Sarah A., Wang, Rong, Pietrzik, Claus U., Findlay, Kirk A., Smith, Tawnya E., Murphy, Michael P., Bulter, Thomas, Kang, David E., Marquez-Sterling, Numa, Golde, Todd E., Koo, Edward H.·2001·Nature

DOI 10.1038/35102591

Cited by (1,001)

Items 601–700 of 1,001

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Presenilin Is the Molecular Target of Acidic γ-Secretase Modulators in Living Cells
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Stefan Pype, Dieder Moechars, Lieve Dillen, Marc H. Mercken · 2003 · Journal of Neurochemistry
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Ibuprofen modifies cognitive disease progression in an Alzheimer’s mouse model
Van Dam, D., Coen, K., De Deyn, PP · 2010 · Journal of Psychopharmacology
Harnessing Immunoproteostasis to Treat Neurodegenerative Disorders
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Sulindac-Derived RXRα Modulators Inhibit Cancer Cell Growth by Binding to a Novel Site
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Martin Pettersson, Gregory W. Kauffman, Christopher W. am Ende, Nandini C. Patel, Cory M. Stiff, Tuan P. Tran, Douglas S. Johnson · 2011 · Expert Opinion on Therapeutic Patents
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Zongmin Li, Marlon Jansen, Sha-Ron Pierre, Maria E. Figueiredo‐Pereira · 2003 · The International Journal of Biochemistry & Cell Biology
Random Mutagenesis of Presenilin-1 Identifies Novel Mutants Exclusively Generating Long Amyloid β-Peptides
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Inflammation takes on Alzheimer disease
Todd Eliot Golde · 2002 · Nature Medicine
Molecular Plasticity Regulates Oligomerization and Cytotoxicity of the Multipeptide-length Amyloid-β Peptide Pool
Annelies Vandersteen, Marcelo F. Masman, Greet De Baets, Wim Jonckheere, Kees van der Werf, ‪Siewert J. Marrink, Jef Rozenski, Iryna Benilova, Bart De Strooper, Vinod Subramaniam et al. · 2012 · Journal of Biological Chemistry
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The Role of β-Amyloid Protein in Synaptic Function: Implications for Alzheimers Disease Therapy
Fernando Peña‐Ortega, Armando I. Gutiérrez-Lerma, Ricardo Quiroz‐Baez, Clorinda Arias · 2006 · Current Neuropharmacology
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Prevention of brain aging and dementia
Linda J Ball, Stanley J. Birge · 2002 · Clinics in Geriatric Medicine
In vitro and in vivo profiling of CHF5022 and CHF5074
Bruno Pietro Imbimbo, Elda Del Giudice, Valentina Cenacchi, Roberta Volta, Gino Villetti, Fabrizio Facchinetti, Benedetta Riccardi, Paola Puccini, Nadia Moretto, Francesca Grassi et al. · 2007 · Pharmacological Research
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Gehad M. Subaiea, Lina I. Adwan, Aseef H. Ahmed, Karen E. Stevens, Nasser H. Zawia · 2013 · Neurobiology of Aging
Activation of microglia: A neuroinflammatory role for CAP37
H. Pereira, Xin-Jian Ruan, Padmasini Kumar · 2003 · Glia
Detection of Alzheimer Peptides and Chemokines in the Aqueous Humor
Sabina M Janciauskiene, Karin Westin, Olof Grip, Torsten Krakau · 2010 · European Journal of Ophthalmology
Effects of (−)Epicatechin on the Pathology of APP/PS1 Transgenic Mice
Zeng Yue-Qin, Yan‐Jiang Wang, Xin‐Fu Zhou · 2014 · Frontiers in Neurology
Amyloid-beta peptide decreases expression and function of glutamate transporters in nervous system cells
Tong, Huichun, Zhang, Xiuping, Meng, Xingjun, Xu, Pingyi, Zou, Xiaoming, Qu, Shaogang · 2017 · The International Journal of Biochemistry & Cell Biology
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Ellen Kilger, Anika Bühler, Heidrun Wölfing, Sathish Kumar, Stephan A. Kaeser, Amudha Nagarathinam, Jochen Walter, Mathias Jucker, Janaky Coomaraswamy · 2011 · Journal of Biological Chemistry
Molecular and Cellular Basis for Anti-Amyloid Therapy in Alzheimer Disease
Sam Gandy, Ralph Nigel Martins, Joseph D. Buxbaum · 2003 · Alzheimer Disease & Associated Disorders
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Gas6 Inhibits Toll-Like Receptor-Mediated Inflammatory Pathways in Mouse Microglia via Axl and Mer
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EFFECT OF NAPROXEN, A NON‐SELECTIVE CYCLO‐OXYGENASE INHIBITOR, ON PENTYLENETETRAZOL‐INDUCED KINDLING IN MICE
Ashish Dhir, Pattipati S. Naidu, Shrinivas K Kulkarni · 2005 · Clinical and Experimental Pharmacology and Physiology
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Alexey Rivkin, Sean P. Ahearn, Stephanie M. Chichetti, Yoona R. Kim, Chaomin Li, Andrew Rosenau, Solomon D. Kattar, Joon O. Jung, Sanjiv Shah, Bethany L. Hughes et al. · 2009 · Bioorganic & Medicinal Chemistry Letters
Pharmacotherapeutic approaches to the prevention of Alzheimer's disease
John B. Standridge · 2004 · The American Journal of Geriatric Pharmacotherapy
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Satinder S. Sarang, Takumi Yoshida, Rodolphe Cadet, Andrew S. Valeras, Roderick V. Jensen, Steven R. Gullans · 2002 · Physiological Genomics
Molecular Rationale for the Pharmacological Treatment of Alzheimer??s Disease
Martina Zimmermann, Fabrizio Gardoni, Mónica Di Luca · 2005 · Drugs & Aging
γ-Secretase Modulator in Alzheimer's Disease: Shifting the End
Weiming Xia, Stephen T. C. Wong, Eugene B. Hanlon, Peter Morin · 2012 · Journal of Alzheimer s Disease
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Celina Zerbinatti, Joanna M. Cordy, Ci-Di Chen, Maria D. Guillily, Sokreine Suon, William J. Ray, Guy R. Seabrook, Carmela R. Abraham, Benjamin L. Wolozin · 2008 · Molecular Neurodegeneration
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Anne Mannila, Jarkko Rautio, Marko Lehtonen, Tomi Järvinen, Jouko Savolainen · 2004 · European Journal of Pharmaceutical Sciences
Nitrous oxide-oxygen or oral midazolam for pediatric outpatient sedation
Sarah A. Hulland, Marshall M Freilich, George K.B. Sándor · 2002 · Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology
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Zongmin Li, Marlon Jansen, Kenyon D. Ogburn, Laura Salvatierra, Lavonne Hunter, Sneha Mathew, Maria E. Figueiredo‐Pereira · 2004 · Journal of Neuroscience Research
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Identification of inhibitors using a cell-based assay for monitoring Golgi-resident protease activity
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