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The rGel/BLyS Fusion Toxin Inhibits Diffuse Large B-cell Lymphoma Growth In Vitro and In Vivo

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The functional role of peroxiredoxin 3 in reactive oxygen species, apoptosis, and chemoresistance of cancer cells

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Hypothermic machine perfusion increases A20 expression which protects renal cells against ischemia/reperfusion injury by suppressing inflammation, apoptosis and necroptosis

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Fos Proteins Suppress Dextran Sulfate Sodium-Induced Colitis through Inhibition of NF-κB

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Gadd45β deficiency in rheumatoid arthritis: Enhanced synovitis through JNK signaling

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GADD45α is highly expressed in pancreatic ductal adenocarcinoma cells and required for tumor cell viability

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NF-κB suppresses ROS levels in BCR–ABL+ cells to prevent activation of JNK and cell death

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Inactivation of Crk SH3 domain-binding guanine nucleotide-releasing factor (C3G) in cervical squamous cell carcinoma

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Alternative Interventions to Prevent Oxidative Damage following Ischemia/Reperfusion

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Loss of Ikkβ Promotes Migration and Proliferation of Mouse Embryo Fibroblast Cells

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Thalidomide Analogues Suppress Lipopolysaccharide-Induced Synthesis of TNF-α and Nitrite, an Intermediate of Nitric Oxide, in a Cellular Model of Inflammation

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Pge1–Induced No Reduces Apoptosis by D–Galactosamine Through Attenuation of Nf–Kb and Nos–2 Expression in Rat Hepatocytes

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Adding Facets to TNF Signaling

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Targeting signal transduction pathways which regulate necrosis in acetaminophen hepatotoxicity

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Gadd45β promotes regeneration after injury through TGFβ-dependent restitution in experimental colitis

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Suppression of hLRH-1 mediated by a DNA vector-based RNA interference results in cell cycle arrest and induction of apoptosis in hepatocellular carcinoma cell BEL-7402

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Nuclear Factor-κB Regulates Inflammatory Cell Apoptosis and Phagocytosis in Rat Carrageenin-Sponge Implant Model

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Nuclear factor-kB in thyroid carcinogenesis and progression: a novel therapeutic target for advanced thyroid cancer

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Sonic hedgehog promotes CD4+ T lymphocyte proliferation and modulates the expression of a subset of CD28-targeted genes

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Role of ischaemic preconditioning in liver regeneration following major liver resection and transplantation

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Miz1 is a signal- and pathway-specific modulator or regulator (SMOR) that suppresses TNF-α-induced JNK1 activation

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Growth arrest and DNA damage protein 45b (Gadd45b) protects retinal ganglion cells from injuries

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Senescence of chondrocytes in aging articular cartilage: GADD45β mediates p21 expression in association with C/EBPβ in senescence-accelerated mice

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JunD-mediated repression of GADD45α and γ regulates escape from cell death in prostate cancer

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Hepatic transcriptional dose-response analysis of male and female Fischer rats exposed to hexabromocyclododecane

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Identification of cytokine-induced nuclear factor-kappaB target genes in ovarian and breast cancer cells

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Suppression of Calcium Release from Inositol 1,4,5-Trisphosphate-sensitive Stores Mediates the Anti-apoptotic Function of Nuclear Factor-κB

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Agonistic Antibody to TLR4/MD-2 Protects Mice from Acute Lethal Hepatitis Induced by TNF-α

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Aberrant Expression of Serpin Squamous Cell Carcinoma Antigen 2 in Human Tumor Tissues and Cell Lines: Evidence of Protection from Tumor Necrosis Factor-Mediated Apoptosis

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DEFICIENCY OF BID PROTEIN REDUCES SEPSIS-INDUCED APOPTOSIS AND INFLAMMATION, WHILE IMPROVING SEPTIC SURVIVAL

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Loss of p24 function in Drosophila melanogaster causes a stress response and increased levels of NF-κB-regulated gene products

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Regulator of calcineurin 1 differentially regulates TLR-dependent MyD88 and TRIF signaling pathways

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Over‐expression of mitogen‐activated protein kinase phosphatase‐2 enhances adhesion molecule expression and protects against apoptosis in human endothelial cells

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Analysis of Ret knockin mice reveals a critical role for IKKs, but not PI 3-K, in neurotrophic factor-induced survival of sympathetic neurons

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A global genomic view of MIF knockdown-mediated cell cycle arrest

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Increased radiation‐induced apoptosis of Saos2 cells via inhibition of NFκB: A role for c‐Jun N‐terminal kinase

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Role of gadd45 in myeloid cells in response to hematopoietic stress

Hoffman‐Liebermann, B., & Liebermann, D. A. (2007) · Blood Cells Molecules and Diseases · doi:10.1016/j.bcmd.2007.06.011 · Cited by 28

A TRAF2 binding independent region of TNFR2 is responsible for TRAF2 depletion and enhancement of cytotoxicity driven by TNFR1

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The histone deacetylase inhibitor trichostatin A induces GADD45γ expression via Oct and NF-Y binding sites

Campanero, M. R., Herrero, A., & Calvo, V. (2007) · Oncogene · doi:10.1038/sj.onc.1210735 · Cited by 28

Gene Expression Profiling in Conjunction with Physiological Rescues of IKKα-null Cells with Wild Type or Mutant IKKα Reveals Distinct Classes of IKKα/NF-κB-dependent Genes

Massa, P. E., Li, X., Hanidu, A., Siamas, J., Pariali, M., Pareja, J., Savitt, A. G., Catron, K. M., Li, J., & Marcu, K. B. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m414401200 · Cited by 28

Targeting erythropoietin for chronic neurodegenerative diseases

Chong, Z. Z., Shang, Y. C., Mu, Y., Cui, S., Yao, Q., & Maiese, K. (2013) · Expert Opinion on Therapeutic Targets · doi:10.1517/14728222.2013.780599 · Cited by 27

Immune cell-mediated liver injury

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Global profiling of influence of intra-ischemic brain temperature on gene expression in rat brain

Kobayashi, M. S., Asai, S., Ishikawa, K., Nishida, Y., Nagata, T., & Takahashi, Y. (2008) · Brain Research Reviews · doi:10.1016/j.brainresrev.2008.03.001 · Cited by 27

H-Ras-specific activation of NF-κB protects NIH 3T3 cells against stimulus-dependent apoptosis

Millán, O., Ballester, A., Castrillo, A., Oliva, J. L., Través, P. G., Rojas, J. M., & Boscá, L. (2003) · Oncogene · doi:10.1038/sj.onc.1206179 · Cited by 27

Gadd45β is transcriptionally activated by p53 via p38α-mediated phosphorylation during myocardial ischemic injury

Kim, Y.-A., Kim, M.-Y., Yu, H. Y., Mishra, S. K., Lee, J.-H., Choi, K. S., Kim, J.-H., Xiang, Y. K., & Jung, Y.-S. (2013) · Journal of Molecular Medicine · doi:10.1007/s00109-013-1070-9 · Cited by 26

Current, emerging, and potential therapies for non-alcoholic steatohepatitis

Yang, Z. L., & Wang, L. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1152042 · Cited by 26

c-Jun N-terminal kinase attenuates TNFα signaling by reducing Nox1-dependent endosomal ROS production in vascular smooth muscle cells

Choi, H., Dikalova, A., Stark, R. J., & Lamb, F. S. (2015) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2015.05.015 · Cited by 27

Depsipeptide induces cell death in Hodgkin lymphoma-derived cell lines

Hartlapp, I., Pallasch, C. P., Weibert, G., Kemkers, A., Hummel, M., & Ré, D. (2009) · Leukemia Research · doi:10.1016/j.leukres.2008.12.013 · Cited by 27

Inhibition of endocytosis exacerbates TNF-α-induced endothelial dysfunction via enhanced JNK and p38 activation

Choi, H., Nguyen, H. N., & Lamb, F. S. (2014) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00885.2013 · Cited by 26

Cell death caused by the synergistic effects of zinc and dopamine is mediated by a stress sensor gene Gadd45b – implication in the pathogenesis of Parkinson's disease

Yang, T., Wu, P., Chung, I., Jiang, J., Fann, M., & Kao, L. (2016) · Journal of Neurochemistry · doi:10.1111/jnc.13728 · Cited by 26

Gadd45γ Expression Is Reduced in Anaplastic Thyroid Cancer and Its Reexpression Results in Apoptosis

Chung, H. K., Yi, Y. W., Jung, N., Kim, D., Suh, J. M., Kim, H., Park, K. C., Kim, D. W., Hwang, E. S., Song, J. H., et al. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-022031 · Cited by 26

Activator protein-1 in human male germ cell apoptosis

Suomalainen, L., Dunkel, L., Ketola, I., Eriksson, M. R., Erkkilä, K., Oksjoki, R. K., Taari, K., Heikinheimo, M., & Pentikäinen, V. (2004) · Molecular Human Reproduction · doi:10.1093/molehr/gah094 · Cited by 26

Transmembrane TNF and IFNγ Induce Caspase-independent Death of Primary Mouse Pancreatic Beta Cells

Irawaty, W., Kay, T. W. H., & Thomas, H. E. (2002) · Autoimmunity · doi:10.1080/0891693021000024834 · Cited by 26

The Putative Tumor Suppressor Tsc-22 is Downregulated Early in Chemically Induced Hepatocarcinogenesis and may be a Suppressor of Gadd45b

Iida, M., Anna, C. H., Gaskin, N. D., Walker, N. J., & Devereux, T. R. (2007) · Toxicological Sciences · doi:10.1093/toxsci/kfm138 · Cited by 26

Polyol pathway-generated fructose is indispensable for growth and survival of non-small cell lung cancer

Schwab, A., Siddiqui, A., Ramesh, V., Gollavilli, P. N., Martinez-Turtos, A., Møller, S. S., Pinna, L., Havelund, J. F., Rømer, A. M. A., Ersan, P. G., et al. (2024) · Cell Death and Differentiation · doi:10.1038/s41418-024-01415-1 · Cited by 28

Restoration of CBX7 expression increases the susceptibility of human lung carcinoma cells to irinotecan treatment

Cacciola, N. A., Sepe, R., Forzati, F., Federico, A., Pellecchia, S., Malapelle, U., Stefano, A. D., Rocco, D., Fusco, A., & Pallante, P. (2015) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-015-1153-y · Cited by 25

NF- B inhibition increases chemosensitivity to trichostatin A-induced cell death of Ki-Ras-transformed human prostate epithelial cells

Kwon, O., Kim, K., Kim, S. O., Ha, R., Oh, W. K., Kim, M., Kim, H., Kim, G. D., Kim, J. W., Jung, M., et al. (2006) · Carcinogenesis · doi:10.1093/carcin/bgl097 · Cited by 25

The protective role of NF-κB and AP-1 in arsenite-induced apoptosis in aortic endothelial cells

Tsou, T., Tsai, F., Wu, M. C., & Chang, L. W. (2003) · Toxicology and Applied Pharmacology · doi:10.1016/s0041-008x(03)00239-4 · Cited by 25

Intra-tumor ROS amplification by melatonin interferes in the apoptosis-autophagy-inflammation-EMT collusion in the breast tumor microenvironment

Das, N., Mukherjee, S., Das, A., Gupta, P., Bandyopadhyay, A., & Chattopadhyay, S. (2023) · Heliyon · doi:10.1016/j.heliyon.2023.e23870 · Cited by 24

Role of GADD45β in the regulation of synovial fluid T cell apoptosis in rheumatoid arthritis

Du, F., Wang, L. L., Zhang, Y., Jiang, W., Sheng, H., Cao, Q., Wu, J., Shen, B., Shen, T.-W., Zhang, J. Z., et al. (2008) · Clinical Immunology · doi:10.1016/j.clim.2008.03.523 · Cited by 24

Gadd45β ameliorates L-DOPA-induced dyskinesia in a Parkinson's disease mouse model

Park, H., Ryu, Y., Kim, Y., Park, T., Go, J., Hwang, J. H., Choi, D., Rhee, M., Lee, C., & Kim, K. (2016) · Neurobiology of Disease · doi:10.1016/j.nbd.2016.02.013 · Cited by 24

RBM3 expression is upregulated by NF‐κB p65 activity, protecting cells from apoptosis, during mild hypothermia

Ushio, A., & Eto, K. (2018) · Journal of Cellular Biochemistry · doi:10.1002/jcb.26757 · Cited by 24

Hemodialysis Modulates Gene Expression Profile in Skeletal Muscle

Shah, V. O., Dominic, E. A., Moseley, P. L., Pickett, G., Fleet, M., Ness, S., & Raj, D. S. (2006) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2006.05.032 · Cited by 24

Activation of the mitochondrial caspase cascade in the absence of protein synthesis does not require c-Jun N-terminal kinase

Watanabe, N., Iwamoto, T., Dickinson, D. A., Iles, K. E., & Forman, H. J. (2002) · Archives of Biochemistry and Biophysics · doi:10.1016/s0003-9861(02)00399-5 · Cited by 24

NF-κB meets ROS: an ‘iron-ic’ encounter

Papa, S., Bubici, C., Pham, C. G., Zazzeroni, F., & Franzoso, G. (2005) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4401694 · Cited by 24

Role of D-GADD45 in JNK-Dependent Apoptosis and Regeneration in Drosophila

Camilleri‐Robles, C., Serras, F., & Corominas, M. (2019) · Genes · doi:10.3390/genes10050378 · Cited by 23

The Dpp/TGFβ-Dependent Corepressor Schnurri Protects Epithelial Cells from JNK-Induced Apoptosis in Drosophila Embryos

Beira, J. V., Springhorn, A., Günther, S., Hufnagel, L., Pyrowolakis, G., & Vincent, J. (2014) · Developmental Cell · doi:10.1016/j.devcel.2014.08.015 · Cited by 22

Retinoid-induced activation of NF-κB in APL cells is not essential for granulocytic differentiation, but prolongs the life span of mature cells

Mathieu, J., Giraudier, S., Lanotte, M., & Besançon, F. (2005) · Oncogene · doi:10.1038/sj.onc.1208889 · Cited by 22

Regulation of inflammatory response in human chondrocytes by lentiviral mediated RNA interference against S100A10

Song, C., Zhou, X., Dong, Q., Fan, R., Wu, G., Ji, B., Meng, Q., & Zheng, M. (2012) · Inflammation Research · doi:10.1007/s00011-012-0519-6 · Cited by 22

trans, trans-2,4-Decadienal, a lipid peroxidation product, induces inflammatory responses via Hsp90- or 14–3-3ζ-dependent mechanisms

Wang, Y., Dattmore, D. A., Wang, W., Pohnert, G., Wolfram, S., Zhang, J., Yang, R., Decker, E. A., Lee, K. S. S., & Zhang, G. (2019) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2019.108286 · Cited by 22

Responding naive T cells differ in their sensitivity to Fas engagement: early death of many T cells is compensated by costimulation of surviving T cells

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Sex-Specific Effects of Environmental Exposure to the Antimicrobial Agents Benzalkonium Chloride and Triclosan on the Gut Microbiota and Health of Zebrafish (Danio rerio)

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