Cited by 1,443Genomics and Chromatin DynamicsProtein Kinase Regulation and GTPase SignalingSignaling Pathways in Disease

The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.

Nuclear protein CBP is a coactivator for the transcription factor CREB

Kwok, Roland P. S., Lundblad, James R., Chrivia, John C., Richards, Jane P., Bächinger, Hans Peter, Brennan, Richard G., Roberts, Stefan G. E., Green, Michael R., Goodman, Richard H.·1994·Nature

DOI 10.1038/370223a0

Open this paper in CoChat — free account

Abstract

The transcription factor CREB binds to a DNA element known as the cAMP-regulated enhancer (CRE). CREB is activated through phosphorylation by protein kinase A (PKA), but precisely how phosphorylation stimulates CREB function is unknown. One model is that phosphorylation may allow the recruitment of coactivators which then interact with basal transcription factors. We have previously identified a nuclear protein of M(r)265K, CBP, that binds specifically to the PKA-phosphorylated form of CREB. We have used fluorescence anisotropy measurements to define the equilibrium binding parameters of the phosphoCREB:CBP interaction and report here that CBP can activate transcription through a region in its carboxy terminus. The activation domain of CBP interacts with the basal transcription factor TFIIB through a domain that is conserved in the yeast coactivator ADA-1 (ref. 8). Consistent with its role as a coactivator, CBP augments the activity of phosphorylated CREB to activate transcription of cAMP-responsive genes.

Integrity signals

Registry

Crossref · 10.1038/370223a0

Cites

19 of 19 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133
Gonzalez, G. A., & Montminy, M. (1989) · Cell · doi:10.1016/0092-8674(89)90013-5 · Cited by 2,464
Phosphorylated CREB binds specifically to the nuclear protein CBP
Chrivia, J. C., Kwok, R. P. S., Lamb, N., Hagiwara, M., Montminy, M. R., & Goodman, R. H. (1993) · Nature · doi:10.1038/365855a0 · Cited by 2,052
Self-citation
Eukaryotic proteins expressed in Escherichia coli: an improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase.
Guan, K., & Dixon, J. (1991) · Analytical Biochemistry · doi:10.1016/0003-2697(91)90534-z · Cited by 1,735
Identification of a cyclic-AMP-responsive element within the rat somatostatin gene.
Montminy, M., Sevarino, K. A., Wagner, J. A., Mandel, G., & Goodman, R. H. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.18.6682 · Cited by 1,385
Self-citation
A cluster of phosphorylation sites on the cyclic AMP-regulated nuclear factor CREB predicted by its sequence
Gonzalez, G. A., Yamamoto, K. K., Fischer, W. H., Karr, D., Menzel, P., Biggs, W., Vale, W., & Montminy, M. (1989) · Nature · doi:10.1038/337749a0 · Cited by 875
A cyclic AMP- and phorbol ester-inducible DNA element
Comb, M. J., Birnberg, N. C., Seasholtz, A. F., Herbert, E., & Goodman, H. M. (1986) · Nature · doi:10.1038/323353a0 · Cited by 741
Cyclic AMP-Responsive DNA-Binding Protein: Structure Based on a Cloned Placental cDNA
Hoeffler, J. P., Meyer, T. E., Yun, Y., Jameson, J. L., & Habener, J. F. (1988) · Science · doi:10.1126/science.2974179 · Cited by 731
Transcription activation by the adenovirus E1a protein
Lillie, J. W., & Green, M. R. (1989) · Nature · doi:10.1038/338039a0 · Cited by 617
Self-citation
Genetic isolation of ADA2: A potential transcriptional adaptor required for function of certain acidic activation domains
Berger, S. L., Piña, B., Silverman, N., Marcus, G. A., Agapite, J., Regier, J. L., Triezenberg, S. J., & Guarente, L. (1992) · Cell · doi:10.1016/0092-8674(92)90100-q · Cited by 435
Drosophila TAFII40 interacts with both a VP16 activation domain and the basal transcription factor TFIIB.
Goodrich, J., Hoey, T., Thut, C., Admon, A., & Tjian, R. (1993) · Cell · doi:10.1016/0092-8674(93)90386-5 · Cited by 417

Show all 19 references

Research works printed but not linked: 1

Gonzalez, G. A. & Montminy, M. R. Cell 59, 675–680 (1989). · DOI

Sorted by citations

Items 901–1,000 of 1,000

Regulation of ania‐6 splice variants by distinct signaling pathways in striatal neurons
Sgambato, V., Minassian, R., Nairn, A. C., & Hyman, S. E. (2003) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2003.01816.x · Cited by 30
Human gastrin‐releasing peptide receptor mediates sustained CREB phosphorylation and transactivation in HuTu 80 duodenal cancer cells
Qu, X., Xiao, D., & Weber, H. C. (2002) · FEBS Letters · doi:10.1016/s0014-5793(02)03177-0 · Cited by 30
Transcriptional Coactivators CBP and p300 Cooperatively Enhance HNF-1 -Mediated Expression of the Albumin Gene in Hepatocytes
Dohda, T. (2004) · The Journal of Biochemistry · doi:10.1093/jb/mvh123 · Cited by 31
The decapentaplegic Core Promoter Region Plays an Integral Role in the Spatial Control of Transcription
Schwyter, D. H., Huang, J., Dubnicoff, T., & Courey, A. J. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.7.3960 · Cited by 30
Cardiac glycosides with target at direct and indirect interactions with nuclear receptors
Karaś, K., Sałkowska, A., Dastych, J., Bachorz, R. A., & Ratajewski, M. (2020) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2020.110106 · Cited by 30
Cardiomyocyte‐specific inactivation of transcription factor CREB in mice
Máťuš, M., Lewin, G., Stümpel, F. T., Buchwalow, I., Schneider, M. D., Schütz, G., Schmitz, W. L., & Müller, F. U. (2007) · The FASEB Journal · doi:10.1096/fj.06-7915com · Cited by 32
Mechanism of Repression of the Inhibin α-Subunit Gene by Inducible 3′,5′-Cyclic Adenosine Monophosphate Early Repressor
Burkart, A. D., Mukherjee, A., & Mayo, K. E. (2005) · Molecular Endocrinology · doi:10.1210/me.2005-0204 · Cited by 29
Beta-adrenergic signaling on neuroendocrine differentiation, angiogenesis, and metastasis in prostate cancer progression
Li, W., & Zhao, Y. (2018) · Asian Journal of Andrology · doi:10.4103/aja.aja_32_18 · Cited by 29
An Activator Protein 1-Like Motif Mediates 17β-Estradiol Repression of Gonadotropin-Releasing Hormone Receptor Promoter via an Estrogen Receptor α-Dependent Mechanism in Ovarian and Breast Cancer Cells
Cheng, C. K., Chow, B., & Leung, P. C. K. (2003) · Molecular Endocrinology · doi:10.1210/me.2003-0217 · Cited by 29
Requirement of Two NFATc4 Transactivation Domains for CBP Potentiation
Yang, T. T. C., Davis, R. J., & Chow, C.-W. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m102961200 · Cited by 29
PPARs in Alveolar Macrophage Biology
Smith, M. R., Standiford, T. J., & Reddy, R. C. (2007) · PPAR Research · doi:10.1155/2007/23812 · Cited by 27
The nucleotide receptor P2RX7 mediates ATP-induced CREB activation in human and murine monocytic cells
Gavala, M. L., Pfeiffer, Z. A., & Bertics, P. J. (2008) · Journal of Leukocyte Biology · doi:10.1189/jlb.0907612 · Cited by 29
Analysis of Molecular Mechanisms Controlling Neuroendocrine Cell Specific Transcription of the Chromogranin A Gene1
Canaff, L., Bevan, S. A., Wheeler, D. G., Mouland, A. J., Rehfuss, R. P., White, J. H., & Hendy, G. N. (1998) · Endocrinology · doi:10.1210/endo.139.3.5851 · Cited by 29
Loss of Heterozygosity and Internal Tandem Duplication Mutations of the CBP Gene Are Frequent Events in Human Esophageal Squamous Cell Carcinoma
So, C.-K., Nie, Y., Song, Y., Yang, G., Chen, S., Wei, C. S.-J., Wang, L., Doggett, N. A., & Yang, C. S. (2004) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-03-0160 · Cited by 29
CD28 Signaling Augments Elk-1-Dependent Transcription at the c- fos Gene During Antigen Stimulation
Li, W., Whaley, C. D., Bonnevier, J. L., Mondino, A., Martin, M. E., Aagaard-Tillery, K. M., & Mueller, D. L. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.167.2.827 · Cited by 29
Copurification of Casein Kinase II with Transcription Factor ATF/E4TF3
Wada, T., Takagi, T., Yamaguchi, Y., Kawase, H., Hiramoto, M., Ferdous, A., Takayama, M., Lee, K. A. W., Hurst, H. C., & Handa, H. (1996) · Nucleic Acids Research · doi:10.1093/nar/24.5.876 · Cited by 29
Molecular approach to human leukemia: Isolation and characterization of the first human retrovirus HTLV-1 and its impact on tumorigenesis in Adult T-cell Leukemia
Yoshida, M. (2010) · Proceedings of the Japan Academy Series B · doi:10.2183/pjab.86.117 · Cited by 28
Ephedrine induced thioredoxin-1 expression through β-adrenergic receptor/cyclic AMP/protein kinase A/dopamine- and cyclic AMP-regulated phosphoprotein signaling pathway
Jia, J., Zeng, X., Li, Y., Ma, S., & Bai, J. (2013) · Cellular Signalling · doi:10.1016/j.cellsig.2013.02.007 · Cited by 28
Lentivirus-mediated RNAi Targeting CREB Binding Protein Attenuates Neointimal Formation and Promotes Re-endothelialization in Balloon Injured Rat Carotid Artery
Yang, J., Jiang, H., Chen, S.-S., Chen, J., Li, W., Xu, S., & Wang, J. (2010) · Cellular Physiology and Biochemistry · doi:10.1159/000320567 · Cited by 28
Zn2+-induced NF-κB-dependent transcriptional activity involves site-specific p65/RelA phosphorylation
Kim, Y.-M., Cao, D., REED, W. A., Wu, W., Jaspers, I., Tal, T. L., Bromberg, P. A., & Samet, J. M. (2006) · Cellular Signalling · doi:10.1016/j.cellsig.2006.08.003 · Cited by 28
Small-Molecule Hormones: Molecular Mechanisms of Action
Puzianowska‐Kuźnicka, M., Pawlik-Pachucka, E., Owczarz, M., Budzińska, M., & Połosak, J. (2013) · International Journal of Endocrinology · doi:10.1155/2013/601246 · Cited by 27
Mechanisms of Injury to the Newborn Brain
Fritz, K. I., & Delivoria‐Papadopoulos, M. (2006) · Clinics in Perinatology · doi:10.1016/j.clp.2006.06.012 · Cited by 28
βc Cytokine Receptor-Induced Stimulation of cAMP Response Element Binding Protein Phosphorylation Requires Protein Kinase C In Myeloid Cells: A Novel Cytokine Signal Transduction Cascade
Gubina, E., Luo, X., Kwon, E. M., Sakamoto, K. M., Shi, Y., & Mufson, R. A. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.167.8.4303 · Cited by 28
Detecting Copy Number Changes in Genomic DNA: MAPH and MLPA
White, S. J., Breuning, M. H., & den Dunnen, J. T. (2004) · Methods in cell biology · doi:10.1016/s0091-679x(04)75032-3 · Cited by 28
Activation of HTLV-I Transcription in the Presence of Tax Is Independent of the Acetylation of CREB-2 (ATF-4)
Gachon, F., Devaux, C. A., & Mesnard, J.-M. (2002) · Virology · doi:10.1006/viro.2002.1501 · Cited by 28
BCL3 Acts as a Negative Regulator of Transcription from the Human T-cell Leukemia Virus Type 1 Long Terminal Repeat through Interactions with TORC3
Hishiki, T., Ohshima, T., Ego, T., & Shimotohno, K. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m702656200 · Cited by 28
A Novel Role of VIP in Colonic Motility Function: Induction of Excitation–Transcription Coupling in Smooth Muscle Cells
Shi, X.-Z. P., Choudhury, B. K., Pasricha, P. J., & Sarna, S. K. (2007) · Gastroenterology · doi:10.1053/j.gastro.2007.02.016 · Cited by 28
Insight Into the Tumor Suppressor Function of CBP Through the Viral Oncoprotein Tax
Orden, K. V., & Nyborg, J. K. (2001) · Gene Expression · doi:10.3727/000000001783992678 · Cited by 28
Nuclear Receptor Coregulators in Hormone-Dependent Cancers
Jafari, H., Hussain, S., & Campbell, M. (2022) · Cancers · doi:10.3390/cancers14102402 · Cited by 21
Immunohistochemical detection of steroid receptor cofactors in ovarian endometriosis: involvement of down-regulated SRC-1 expression in the limited growth activity of the endometriotic epithelium
鈴木, 昭., Horiuchi, A., Oka, K., Miyamoto, T., Kashima, H., & Shiozawa, T. (2010) · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin · doi:10.1007/s00428-010-0884-x · Cited by 27
Cyclic AMP‐Dependent Activation of the Proenkephalin Gene Requires Phosphorylation of CREB at Serine‐133 and a Src‐Related Kinase
Kobierski, L. A., Wong, A. E., Srivastava, S., Borsook, D., & Hyman, S. E. (1999) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1999.0730129.x · Cited by 27
Urotensin II-induced store-operated Ca2+ entry contributes to glomerular mesangial cell proliferation and extracellular matrix protein production under high glucose conditions
Soni, H., & Adebiyi, A. (2017) · Scientific Reports · doi:10.1038/s41598-017-18143-x · Cited by 27
NGF‐dependent and tissue‐specific transcription of vgf is regulated by a CREB–p300 and bHLH factor interaction
Mandolesi, G., Gargano, S., Pennuto, M., Illi, B., Molfetta, R., Soucek, L., Mosca, L., Levi, A., Jucker, R., & Nasi, S. (2001) · FEBS Letters · doi:10.1016/s0014-5793(01)03227-6 · Cited by 27
Anticancer effect of retinoic acid via AP-1 activity repression is mediated by retinoic acid receptor α and β in gastric cancer cells
Wu, Q., Chen, Z., & Su, W. (2002) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/s1357-2725(02)00030-4 · Cited by 27
The Interferon Antagonist ML Protein of Thogoto Virus Targets General Transcription Factor IIB
Vogt, C., Preuß, E., Mayer, D., Weber, F., Schwemmle, M., & Kochs, G. (2008) · Journal of Virology · doi:10.1128/jvi.01284-08 · Cited by 27
Fibroblast Growth Factor Receptor 3 Gene Transcription Is Suppressed by Cyclic Adenosine 3′,5′-Monophosphate
McEwen, D. G., Green, R. P., Naski, M. C., Towler, D. A., & Ornitz, D. M. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.43.30934 · Cited by 27
Heterogeneous Nuclear Ribonucleoprotein R Enhances Transcription from the Naturally Configured c-fos Promoter in Vitro*
Fukuda, A., Nakadai, T., Shimada, M., & Hisatake, K. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.013656 · Cited by 23
p300 is involved in formation of the TBP–TFIIA‐containing basal transcription complex, TAC
Mitsiou, D. J., & Stunnenberg, H. G. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg419 · Cited by 27
The Multifunctional Role of E1A in the Transcriptional Regulation of CREB/CBP-Dependent Target Genes
Brockmann, D., & Esche, H. (2003) · Current topics in microbiology and immunology · doi:10.1007/978-3-662-05597-7_4 · Cited by 27
Inhibition of the endothelial cell activation by antithrombin in vitro
Uchiba, M., Kaun, C., Wojta, J., Binder, B. R., & Okajima, K. (2004) · Thrombosis and Haemostasis · doi:10.1160/th04-03-0139 · Cited by 27
Occurrence of a transcription factor, cAMP response element-binding protein (CREB), in the postsynaptic sites of the brain
Suzuki, T., Usuda, N., Ishiguro, H., Mitake, S., Nagatsu, T., & Okumura‐Noji, K. (1998) · Molecular Brain Research · doi:10.1016/s0169-328x(98)00199-5 · Cited by 27
Transcriptional Regulation of the p67 Gene
Li, S.-L., Valente, A. J., Wang, L., Gamez, M. J., & Clark, R. A. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m106111200 · Cited by 27
KATapulting toward Pluripotency and Cancer
Hirsch, C. L., Wrana, J. L., & Dent, S. (2016) · Journal of Molecular Biology · doi:10.1016/j.jmb.2016.09.023 · Cited by 27
Characterization and function of CREB homologue from Crassostrea ariakensis stimulated by rickettsia-like organism
Zhu, B., & Wu, X. (2008) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2008.05.012 · Cited by 26
The Role of Basic Leucine Zipper Protein‐Mediated Transcription in Physiological and Pathological Myocardial Hypertrophy
Kehat, I., Hasin, T., & Aronheim, A. (2006) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1380.009 · Cited by 26
Generation of a conditional CREB Ser133Ala knockin mouse
Wingate, A. D., Martin, K. J., Hunter, C. J., Carr, J. M., Clacher, C., & Arthur, J. S. C. (2009) · genesis · doi:10.1002/dvg.20548 · Cited by 26
The cAMP-responsive element binding protein (CREB) regulates the expression of acid ceramidase (ASAH1) in H295R human adrenocortical cells
Lucki, N. C., & Sewer, M. B. (2009) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2009.03.005 · Cited by 28
Cigarette smoke suppresses in vitro allergic activation of mouse mast cells
Mortaz, E., Folkerts, G., Engels, F., Nijkamp, F. P., & Redegeld, F. A. (2009) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.2009.03209.x · Cited by 26
The N-Terminal A/B Domain of the Thyroid Hormone Receptor-β2 Isoform Influences Ligand-Dependent Recruitment of Coactivators to the Ligand-Binding Domain
Tian, H., Mahajan, M., Wong, C., Habeos, I., & Samuels, H. H. (2006) · Molecular Endocrinology · doi:10.1210/me.2005-0437 · Cited by 26
Colorectal Carcinogenesis: Connecting K-RAS–Induced Transformation and CREB Activity In Vitro and In Vivo
Steven, A., Heiduk, M., Recktenwald, C. V., Hiebl, B., Wickenhauser, C., Massa, C., & Seliger, B. (2015) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-14-0590 · Cited by 26
Differences in the Interactions of Oncogenic Adenovirus 12 Early Region 1A and Nononcogenic Adenovirus 2 Early Region 1A with the Cellular Coactivators p300 and CBP
Lipinski, K. S., Fax, P., Wilker, B., Hennemann, H., Brockmann, D., & Esche, H. (1999) · Virology · doi:10.1006/viro.1998.9583 · Cited by 26
Stimulus-specific Interaction between Activator-Coactivator Cognates Revealed with a Novel Complex-specific Antiserum
Wagner, B. L., Bauer, A., Schütz, G., & Montminy, M. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.12.8263 · Cited by 26
Inhibitory Effect of AP-1 Complex on 5-Aminolevulinate Synthase Gene Expression through Sequestration of cAMP-response Element Protein (CRE)-binding Protein (CBP) Coactivator
Guberman, A., Scassa, M. É., Giono, L. E., Varone, C. L., & Cánepa, E. T. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m205057200 · Cited by 26
Chromatin landscape at cis-regulatory elements orchestrates cell fate decisions in early embryogenesis
Cardamone, F., Piva, A., Löser, E., Eichenberger, B., Romero-Mulero, M. C., Zenk, F. L., Shields, E. J., Cabezas‐Wallscheid, N., Bonasio, R., Tiana, G., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-57719-4 · Cited by 28
The impact of chromatin organization of vitamin D target genes.
Carlberg, C., & Dunlop, T. W. (2006) · PubMed · Cited by 25
Protein kinase A and mitogen‐activated protein kinase pathways mediate cAMP induction of α‐Epithelial Na+ channels (α‐ENaC)
Mustafa, S. B., Castro, R. J., Falck, A. J., Petershack, J. A., Henson, B. M., Mendoza, Y. M., Choudary, A., & SEIDNER, S. R. (2007) · Journal of Cellular Physiology · doi:10.1002/jcp.21291 · Cited by 25
ARR19 (Androgen Receptor Corepressor of 19 kDa), an Antisteroidogenic Factor, Is Regulated by GATA-1 in Testicular Leydig Cells
Qamar, I., Park, E., Gong, E., Lee, H. J., & Lee, K. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m900896200 · Cited by 25
Phosphorylation of the IDP KID Modulates Affinity for KIX by Increasing the Lifetime of the Complex
Dahal, L., Shammas, S. L., & Clarke, J. (2017) · Biophysical Journal · doi:10.1016/j.bpj.2017.10.015 · Cited by 25
Epigenetic Regulation as a Basis for Long-Term Changes in the Nervous System: In Search of Specificity Mechanisms
Borodinova, A. A., & Balaban, P. M. (2020) · Biochemistry (Moscow) · doi:10.1134/s0006297920090023 · Cited by 25
CREB and phospho-CREB interact with RFX5 and CIITA to regulate MHC class II genes
Lochamy, J., Rogers, E. M., & Boss, J. M. (2006) · Molecular Immunology · doi:10.1016/j.molimm.2006.04.004 · Cited by 25
Distinct cAMP response element-binding protein (CREB) domains stimulate different steps in a concerted mechanism of transcription activation
Kim, J., Lu, J., & Quinn, P. G. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.21.11292 · Cited by 25
Distribution of co‐activators CBP and p300 during mouse oocyte and embryo development
Kwok, R. P. S., Liu, X., & Smith, G. D. (2006) · Molecular Reproduction and Development · doi:10.1002/mrd.20440 · Cited by 25
Self-citation
A Novel Cell-Based Assay for G-Protein-Coupled Receptor–Mediated Cyclic Adenosine Monophosphate Response Element Binding Protein Phosphorylation
Selkirk, J. V., Nottebaum, L. M., Ford, I. C., Santos, M. A., Malany, S., Foster, A. C., & Lechner, S. M. (2006) · SLAS DISCOVERY · doi:10.1177/1087057106286608 · Cited by 25
Multiple Transcription Factors Regulate the Inducible Expression of the Human Complement Receptor 2 Promoter
Vereshchagina, L. A., Tolnay, M., & Tsokos, G. C. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.166.10.6156 · Cited by 25
Expression of cAMP Response Element Binding Protein‐Binding Protein in the Song Control System and Hypothalamus of Adult European Starlings (Sturnus vulgaris)
Auger, C. J., Bentley, G. E., Auger, A. P., Ramamurthy, M., & Ball, G. F. (2002) · Journal of Neuroendocrinology · doi:10.1046/j.1365-2826.2002.00842.x · Cited by 25
DNA Binding-independent Transcriptional Activation by the Androgen Receptor through Triggering of Coactivators
Slagsvold, T., Christiansen, I. K., Frønsdal, K. B., & Saatcioglu, F. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m104310200 · Cited by 25
CRE-decoy oligonucleotide-inhibition of gene expression and tumor growth.
Cho‐Chung, Y. S., Park, Y., Nesterova, M., Lee, Y. N., & Cho, Y. S. (2000) · PubMed · Cited by 25
Signal Transduction Pathways Combining Peptide Hormones and Steroidogenesis
Waterman, M. R., & Keeney, D. S. (1996) · Vitamins and hormones · doi:10.1016/s0083-6729(08)60409-4 · Cited by 24
The adenovirus 12 E1A proteins can bind directly to proteins of the p300 transcription co-activator family, including the CREB-binding protein CBP and p300.
Dorsman, J. C., Teunisse, A. F. A. S., ZANTEMA, A., & van der Eb, A. J. (1997) · Journal of General Virology · doi:10.1099/0022-1317-78-2-423 · Cited by 26
INSIGHT: Pit-1/GHF-1: a pituitary-specific transcription factor linking general signaling pathways to cell-specific gene expression
Gutierrez‐Hartmann, A. (1994) · Molecular Endocrinology · doi:10.1210/me.8.11.1447 · Cited by 25
Genetic and phenotypic changes associated with the acquisition of tumorigenicity in human bladder cancer
Gildea, J. J., Golden, W. L., Harding, M. A., & Theodorescu, D. (2000) · Genes Chromosomes and Cancer · doi:10.1002/(sici)1098-2264(200003)27:3 · Cited by 78
The transcription factor code: a beacon for histone methyltransferase docking
Garcia, G. T., & Graf, T. (2021) · Trends in Cell Biology · doi:10.1016/j.tcb.2021.04.001 · Cited by 27
Differential Role for Cyclic AMP Response Element Binding Protein-1 in Multiple Stages of B Cell Development, Differentiation, and Survival
Chen, H., Byrd, J. C., & Muthusamy, N. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.176.4.2208 · Cited by 24
Monocyte 15-Lipoxygenase Gene Expression Requires ERK1/2 MAPK Activity
Bhattacharjee, A., Mulya, A., Pal, S., Roy, B., Feldman, G. M., & Cathcart, M. K. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.1000514 · Cited by 24
Nuclear-Cytoplasmic Shuttling of a RING-IBR Protein RBCK1 and Its Functional Interaction with Nuclear Body Proteins
Tatematsu, K., Yoshimoto, N., Koyanagi, T., Tokunaga, C., Tachibana, T., Yoneda, Y., Yoshida, M., Okajima, T., Tanizawa, K., & Kuroda, S. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m413476200 · Cited by 24
Cooperative regulation of endogenous cAMP-response element binding protein and CCAAT/enhancer-binding protein β in GH-stimulated c-fos expression
Cui, T. X., Kwok, R. P. S., & Schwartz, J. (2007) · Journal of Endocrinology · doi:10.1677/joe-07-0169 · Cited by 24
Self-citation
Sex Differences in the Developing Brain: Crossroads in the Phosphorylation of cAMP Response Element Binding Protein
Auger, A. P. (2003) · Journal of Neuroendocrinology · doi:10.1046/j.1365-2826.2003.01041.x · Cited by 24
Induction of serum‐ and glucocorticoid‐induced kinase‐1 (SGK1) by cAMP regulates increases in α‐ENaC
Vasquez, M. M., Castro, R. J., SEIDNER, S. R., Henson, B. M., Ashton, D. J., & Mustafa, S. B. (2008) · Journal of Cellular Physiology · doi:10.1002/jcp.21534 · Cited by 24
Regulation of the Primate Corpus Luteum: Cellular and Molecular Perspectives
Zeleznik, A. J., & Somers, J. P. (1999) · Trends in Endocrinology and Metabolism · doi:10.1016/s1043-2760(98)00145-3 · Cited by 24
Insulin Inhibits Dexamethasone Effect on Angiotensinogen Gene Expression and Induction of Hypertrophy in Rat Kidney Proximal Tubular Cells in High Glucose
Zhang, S., Chen, X., Wei, C., Filep, J. G., Tang, S., Ingelfinger, J. R., & Chan, J. S. D. (2002) · Endocrinology · doi:10.1210/en.2002-220408 · Cited by 24
Kinetic Study of Phosphorylation‐Dependent Complex Formation between the Kinase‐Inducible Domain (KID) of CREB and the KIX Domain of CBP on a Quartz Crystal Microbalance
Matsuno, H., Furusawa, H., & Okahata, Y. (2004) · Chemistry - A European Journal · doi:10.1002/chem.200400030 · Cited by 24
Phosphorylation of ATF-1 enhances its DNA binding and transcription of the Na,K-ATPase 1 subunit gene promoter
Kobayashi, M., Shimomura, A., Hagiwara, M., & Kawakami, K. (1997) · Nucleic Acids Research · doi:10.1093/nar/25.4.877 · Cited by 24
Effects of the SANT Domain of Tension-Induced/Inhibited Proteins (TIPs), Novel Partners of the Histone Acetyltransferase p300, on p300 Activity and TIP-6-Induced Adipogenesis
Badri, K. R., Zhou, Y., Dhru, U., Aramgam, S., & Schuger, L. A. (2008) · Molecular and Cellular Biology · doi:10.1128/mcb.00333-08 · Cited by 23
CREB Binding Protein (CBP) Activation Is Required for Luteinizing Hormone Beta Expression and Normal Fertility in Mice
Miller, R. S., Wolfe, A., He, L., Radovick, S., & Wondisford, F. E. (2012) · Molecular and Cellular Biology · doi:10.1128/mcb.00394-12 · Cited by 26
Nuclear receptors, their coactivators and modulation of transcription.
Manteuffel-Cymborowska, M. (1999) · Acta Biochimica Polonica · doi:10.18388/abp.1999_4185 · Cited by 24
Effect of Ligand and DNA Binding on the Interaction between Human Transcription Intermediary Factor 1α and Estrogen Receptors
Thénot, S., Bonnet, S., Boulahtouf, A., Margeat, E., Royer, C. A., Borgna, J., & Cavaillès, V. (1999) · Molecular Endocrinology · doi:10.1210/mend.13.12.0387 · Cited by 24
Regulation of Cyclic Adenosine 3′,5′-Monophosphate Response Element Binding Protein (CREB) Expression by Sp1 in the Mammalian Testis1
Shell, S. A., Fix, C., Olejniczak, D. M., Gram-Humphrey, N., & Walker, W. H. (2002) · Biology of Reproduction · doi:10.1095/biolreprod66.3.659 · Cited by 24
Glucocorticoid inhibits growth factor‐induced differentiation of hippocampal progenitor HiB5 cells
Son, G. H., Geum, D., Jung, H., & Kim, K. (2001) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2001.00634.x · Cited by 23
Insights into Transcriptional Regulation of Hepatic Glucose Production
Anyamaneeratch, K., Rojvirat, P., Sukjoi, W., & Jitrapakdee, S. (2015) · International review of cytology · doi:10.1016/bs.ircmb.2015.05.004 · Cited by 25
The acetyltransferase activity of Drosophila CBP is dispensable for regulation of the Dpp pathway in the early embryo
Lilja, T., Aihara, H., Stabell, M., Nibu, Y., & Mannervik, M. (2007) · Developmental Biology · doi:10.1016/j.ydbio.2007.01.036 · Cited by 23
The potential benefit of combined versus monotherapy of coenzyme Q10 and fluoxetine on depressive-like behaviors and intermediates coupled to Gsk-3β in rats
Abuelezz, S. A., Hendawy, N., & Magdy, Y. (2017) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2017.12.018 · Cited by 23
The Co-activator CREB-binding Protein Participates in Enhancer-dependent Activities of Bicoid
Fu, D., Wen, Y., & Ma, J. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m407066200 · Cited by 22
Effect of opioids on Ca2+ /cAMP responsive element binding protein
Bilecki, W., & Przewłocki, R. (2000) · Acta Neurobiologiae Experimentalis · doi:10.55782/ane-2000-1376 · Cited by 23
Transcriptional activation of the F1F0 ATP synthase α-subunit initiator element by USF2 is mediated by p300
Breen, G. A. M., & Jordan, E. M. (1999) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/s0304-4165(99)00061-6 · Cited by 23
Transcriptional Repression by Human Adenovirus E1A N Terminus/Conserved Domain 1 Polypeptides in Vivo and in Vitro in the Absence of Protein Synthesis
Song, C.-Z., Tierney, C. J., Loewenstein, P. M., Pusztai, R., Symington, J. S., Tang, Q., Tóth, K., Nishikawa, A., Bayley, S. T., & Green, M. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.40.23263 · Cited by 23
Self-citation
Mutations of thyrotropin receptor gene
Porcellini, A., Fenzi, G., & Avvedimento, E. V. (1997) · Journal of Molecular Medicine · doi:10.1007/s001090050141 · Cited by 24
Identification and Characterization of a Novel Transcriptional Activation Domain in the CREB-binding Protein
Bisotto, S., Minorgan, S., & Rehfuss, R. P. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.30.17746 · Cited by 23
Nuclear translocation of the catalytic subunit of protein kinase A induced by an antisense oligonucleotide directed against the RIα regulatory subunit
Neary, C. L., & Cho‐Chung, Y. S. (2001) · Oncogene · doi:10.1038/sj.onc.1204992 · Cited by 23
Untitled work
Melcangi (1999) · doi:10.1002/(sici)1097-4695(19990915)40:4
Untitled work
Wilson (1999) · doi:10.1002/1529-0131(199907)42:7

Authors: Kwok, R. P. S., Lundblad, J. R., Chrivia, J. C., Richards, J. P., Bächinger, H. P., Brennan, R. G., Roberts, S. G. E., Green, M. R., & Goodman, R. H.
Affiliations: Oregon Health & Science University (US)
ORCID: Brennan, Richard G.
Roberts, Stefan G. E.
Green, Michael R.
Venue: Nature
Publisher: Springer Science and Business Media LLC
Published: 1994-07
Volume: 370
Issue: 6486
Pages: 223-226
ISSN: 0028-0836 (ISSN-L)
1476-4687
DOI: 10.1038/370223a0
OpenAlex: W1964337986
Cited by: 1,443
References: 19
Citations by year: 2026: 3 · 2025: 10 · 2024: 15 · 2023: 10 · 2022: 16 · 2021: 15 · 2020: 15 · 2019: 7 · 2018: 18 · 2017: 21 · 2016: 22 · 2015: 13 · 2014: 21 · 2013: 29 · 2012: 36
FWCI: 30.10
Type: journal article
Language: en
Open access: closed
Licence: www.springer.com/tdm (tdm)
Locations: Nature (publishedVersion)
PubMed (publishedVersion)
Research Explorer (The University of Manchester) (submittedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Chromatin Dynamics
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Kinase Regulation and GTPase Signaling
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Signaling Pathways in Disease
Keywords: CBP, CREB, transcriptional coactivator, transcriptional activation, protein kinase A phosphorylation, TFIIB, protein-protein interaction
MeSH terms: Animals, Base Sequence, Binding Sites, DNA, Enhancer Elements, Genetic, Fluorescence Polarization, Molecular Sequence Data, Nuclear Proteins, Phosphorylation, Protein Binding, Recombinant Fusion Proteins, Somatostatin, Transcription Factors, Transcription, Genetic, Tumor Cells, Cultured, Trans-Activators, Zinc Fingers, PC12 Cells, Cyclic AMP Response Element-Binding Protein, Transcription Factor TFIIB, CREB-Binding Protein, Mice

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Nuclear protein CBP is a coactivator for the transcription factor CREB

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks