Radiation-induced cell cycle arrest compromised by p21 deficiency

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Items 301–400 of 1,001

1. The Metastasis-Associated Gene Prl-3 Is a p53 Target Involved in Cell-Cycle Regulation
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2. A Limited Role for p21Cip1/Waf1 in Maintaining Normal Hematopoietic Stem Cell Functioning
   Ronald P. van Os, Leonie M. Kamminga, Albertina Ausema, Leonid V Bystrykh, Deanna P. Draijer, Kyrjon van Pelt, Bert Dontje, Gerald de Haan · 2006 · Stem Cells
3. A new pathway for mitogen-dependent Cdk2 regulation uncovered in p27Kip1-deficient cells
   Steve Coats, Peter Whyte, Matthew L. Fero, Susan E. Lacy, Grace Chung, Erin Randel, Eduardo J. Firpo, James M. Roberts · 1999 · Current Biology
4. Arsenic trioxide inhibits the growth of A498 renal cell carcinoma cells via cell cycle arrest or apoptosis
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5. Cell cycle inhibitors in normal and tumor stem cells.
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6. Runx1 Directly Promotes Proliferation of Hair Follicle Stem Cells and Epithelial Tumor Formation in Mouse Skin
   Charlene S. L. Hoi, Song Eun Lee, Shu-Yang Lu, David J. McDermitt, Karen M. Osorio, Caroline M. Piskun, Rachel M. Peters, Ralf Paus, Tudorita Tumbar · 2010 · Molecular and Cellular Biology
7. Neurotransmitter receptor activation triggers p27Kip1 and p21CIP1 accumulation and G1 cell cycle arrest in oligodendrocyte progenitors
   Cristina Antonella Ghiani, Alex M. Eisen, Xiaoqing Q Yuan, Ronald Anthony DePinho, Chris J. McBain, Vittorio Gallo · 1999 · Development
8. Identification of a novel class of genomic DNA-binding sites suggests a mechanism for selectivity in target gene activation by the tumor suppressor protein p53
   Lois Resnick‐Silverman, Selvon St. Clair, Matthew Maurer, Kathy Zhao, James J. Manfredi · 1998 · Genes & Development
9. The G₂ Checkpoint Is Maintained by Redundant Pathways
   Passalaris, Tina M., Benanti, Jennifer A., Gewin, Lindy, Kiyono, Tohru, Galloway, Denise A. · 1999 · Molecular and Cellular Biology
10. Acetylation of Mouse p53 at Lysine 317 Negatively Regulates p53 Apoptotic Activities after DNA Damage
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11. The proteasome as a druggable target with multiple therapeutic potentialities: Cutting and non-cutting edges
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12. Fisetin Inhibits the Activities of Cyclin-Dependent Kinases Leading to Cell Cycle Arrest in HT-29 Human Colon Cancer Cells
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13. SSeCKS, a Major Protein Kinase C Substrate with Tumor Suppressor Activity, Regulates G1→S Progression by Controlling the Expression and Cellular Compartmentalization of Cyclin D
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14. CDK-Independent and PCNA-Dependent Functions of p21 in DNA Replication
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15. High mitogenic stimulation arrests angiogenesis
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16. Death squads enlisted by the tumour suppressor p53
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17. Expression of INK4 inhibitors of cyclin D-dependent kinases during mouse brain development.
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18. Nuclear expression of human apurinic/apyrimidinic endonuclease (HAP1/Ref-1) in head-and-neck cancer is associated with resistance to chemoradiotherapy and poor outcome
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19. Photodynamic therapy results in induction of WAF1/CIP1/P21 leading to cell cycle arrest and apoptosis
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20. A question of balance: the role of cyclin-kinase inhibitors in development and tumorigenesis
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21. Neither p21WAF1 nor 14-3-3sigma prevents G2 progression to mitotic catastrophe in human colon carcinoma cells after DNA damage, but p21WAF1 induces stable G1 arrest in resulting tetraploid cells.
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22. Mécanismes moléculaires contrôlant le cycle cellulaire : aspects fondamentaux et implications en cancérologie
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23. Pretreatment with DNA-damaging agents permits selective killing of checkpoint-deficient cells by microtubule-active drugs
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24. Activation of the p53-dependent G1 checkpoint response in mouse embryo fibroblasts depends on the specific DNA damage inducer
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25. Akt Controls Vascular Smooth Muscle Cell Proliferation In Vitro and In Vivo by Delaying G1/S Exit
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26. Overexpression of EZH2 in multiple myeloma is associated with poor prognosis and dysregulation of cell cycle control
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27. p21 delays tumor onset by preservation of chromosomal stability
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28. p21 is essential for normal myogenic progenitor cell function in regenerating skeletal muscle
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29. A deep dive into UV-based phototherapy: Mechanisms of action and emerging molecular targets in inflammation and cancer
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30. Constitutive expression of E2F-1 leads to p21-dependent cell cycle arrest in S phase of the cell cycle
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31. A p53-dependent S-phase checkpoint helps to protect cells from DNA damage in response to starvation for pyrimidine nucleotides
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32. Apoptosis of leukocytes triggered by acute DNA damage promotes lymphoma formation
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33. Cooperation between p21 and Akt is required for p53‐dependent cellular senescence
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34. Negative cross‐talk between p53 and the glucocorticoid receptor and its role in neuroblastoma cells
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35. The p53 Pathway Controls SOX2-Mediated Reprogramming in the Adult Mouse Spinal Cord
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36. Cytoplasmic p21 WAF1/CIP1 expression is correlated with HER-2/ neu in breast cancer and is an independent predictor of prognosis
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37. Pleurotus ostreatus inhibits proliferation of human breast and colon cancer cells through p53-dependent as well as p53-independent pathway
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38. p53-Dependent Association between Cyclin G and the B′ Subunit of Protein Phosphatase 2A
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39. Double indemnity: p53, BRCA and cancer
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40. Loss of p53 Induces Tumorigenesis in p21-Deficient Mesenchymal Stem Cells
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41. Role of p53 in Apoptosis
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42. Definition of the p53 Functional Domains Necessary for Inducing Apoptosis
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43. Cellular growth state differentially regulates enterocyte gene expression in butyrate-treated HT-29 cells.
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44. The Phosphatase MKP1 Is a Transcriptional Target of p53 Involved in Cell Cycle Regulation
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45. Differential requirement for p19ARF in the p53-dependent arrest induced by DNA damage, microtubule disruption, and ribonucleotide depletion
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46. Radiation-Induced p53 and p21WAF–1/CIP1 Expression in the Murine Intestinal Epithelium
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47. High and low fluences of alpha-particles induce a G1 checkpoint in human diploid fibroblasts.
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48. Involvement of p53 and p21 in Cellular Defects and Tumorigenesis in Atm−/− Mice
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49. Single-nucleotide Polymorphisms in the p53 Signaling Pathway
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50. CDK inhibitors, p21Cip1 and p27Kip1, participate in cell cycle exit of mammalian cardiomyocytes
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51. The hallmarks of CDKN1C (p57, KIP2) in cancer
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52. Fibroblast Growth Factor Inhibits Chondrocytic Growth through Induction of p21 and Subsequent Inactivation of Cyclin E-Cdk2
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53. Preoperative radiotherapy for rectal cancer: implications for surgeons, pathologists and radiologists
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54. Regulation of p53 Sequence-specific DNA-binding by Covalent Poly(ADP-ribosyl)ation
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55. DNA damage response of A549 cells treated with particulate matter (PM 10 ) of urban air pollutants
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56. The roles and regulation of TBX3 in development and disease
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57. Kynurenine inhibits autophagy and promotes senescence in aged bone marrow mesenchymal stem cells through the aryl hydrocarbon receptor pathway
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58. Reactive Oxygen Species and Mitochondrial Sensitivity to Oxidative Stress Determine Induction of Cancer Cell Death by p21
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59. Role of Cyclin-Dependent Kinases and Their Inhibitors in Cellular Differentiation and Development
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60. Cell-cycle control and renal disease
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61. RB signaling prevents replication-dependent DNA double-strand breaks following genotoxic insult
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62. MCG10, a Novel p53 Target Gene That Encodes a KH Domain RNA-Binding Protein, Is Capable of Inducing Apoptosis and Cell Cycle Arrest in G2-M
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63. CDX2, a homeobox transcription factor, upregulates transcription of the p21/WAF1/CIP1 gene
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64. Tumor suppression by p27Kip1 and p21Cip1 during chemically induced skin carcinogenesis
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68. Distinct Role of cAMP and cGMP in the Cell Cycle Control of Vascular Smooth Muscle Cells
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70. Tumor Suppressor Activity of AP2α Mediated through a Direct Interaction with p53
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71. Uncoupling Cancer Mutations Reveals Critical Timing of p53 Loss in Sarcomagenesis
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72. p19Ink4dand p21Cip1Collaborate to Maintain the Postmitotic State of Auditory Hair Cells, Their Codeletion Leading to DNA Damage and p53-Mediated Apoptosis
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73. An overview of the cell cycle arrest protein, p21WAF1
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74. Antiproliferative B cell translocation gene 2 protein is down-regulated post-transcriptionally as an early event in prostate carcinogenesis
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75. Developmental Regulation and In Vitro Culture Effects on Expression of DNA Repair and Cell Cycle Checkpoint Control Genes in Rhesus Monkey Oocytes and Embryos1
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76. Stress hormones reduce the efficacy of paclitaxel in triple negative breast cancer through induction of DNA damage
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77. The p53 circuit board
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78. Anticancer Effects of Thymoquinone, Caffeic Acid Phenethyl Ester and Resveratrol on A549 Non-small Cell Lung Cancer Cells Exposed to Benzo(a)pyrene
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79. The p53 Tumor Suppressor Causes Congenital Malformations in Rpl24-Deficient Mice and Promotes Their Survival
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80. Tumor suppressor functions for the Cdk inhibitor p21 in the mouse colon
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81. Rapid alterations of cell cycle control proteins in human T lymphocytes in microgravity
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82. Emodin, aloe-emodin and rhein induced DNA damage and inhibited DNA repair gene expression in SCC-4 human tongue cancer cells.
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84. Loss of p21WAF1/CIP1 accelerates Ras oncogenesis in a transgenic/knockout mammary cancer model
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86. Selective Requirement for c-Myc at an Early Stage of Vα14i NKT Cell Development
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88. Cell Cycle Regulation and p53 Activation by Protein Phosphatase 2Cα
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89. SIRT1 is involved in oncogenic signaling mediated by GPER in breast cancer
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93. Long noncoding RNAs in the p53 network
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94. Apoptosis and the cell cycle
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95. p53-dependent expression of PIG3 during proliferation, genotoxic stress, and reversible growth arrest
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97. Common Fragile Sites: Genomic Hotspots of DNA Damage and Carcinogenesis
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98. NAD+ Modulates p53 DNA Binding Specificity and Function
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99. Expression of p53, p21 and cyclin D1 in penile cancer: p53 predicts poor prognosis
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