Radiation-induced cell cycle arrest compromised by p21 deficiency

Brugarolas, James, Chandrasekaran, Chitra, Gordon, Jeffrey I., Beach, David, Jacks, Tyler, Hannon, Gregory J.·1995·Nature
DOI 10.1038/377552a0

Cited by (1,000)

Items 101–200 of 1,000

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  2. Tumor susceptibility of p21(Waf1/Cip1)-deficient mice.
    Juan Martín‐Caballero, Juana María Flores, Pilar Garcı́a, Manuel Serrano · 2001 · PubMed
  3. Nuclear Accumulation of p21 Cip1 at the Onset of Mitosis: a Role at the G 2 /M-Phase Transition
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  5. Highly penetrant, rapid tumorigenesis through conditional inversion of the tumor suppressor gene Snf5
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  6. p53 in signaling checkpoint arrest or apoptosis
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  7. Tumor-Suppressor Functions of the TP53 Pathway
    Brandon J. Aubrey, Andreas Strasser, Gemma L. Kelly · 2016 · Cold Spring Harbor Perspectives in Medicine
  8. The p53 tumor suppressor participates in multiple cell cycle checkpoints
    Luciana E. Giono, James J. Manfredi · 2006 · Journal of Cellular Physiology
  9. Cooperation of the tumour suppressors IRF-1 and p53 in response to DNA damage
    Nobuyuki Tanaka, Masahiko Ishihara, Marc S. Lamphier, Hiroaki Nozawa, T. Matsuyama, Tak W. Mak, Shinichi Aizawa, Takashi Tokino, Moshe Oren, Tadatsugu Taniguchi · 1996 · Nature
  10. Cyclin-Binding Motifs Are Essential for the Function of p21 CIP1
    Chen, Junjie, Saha, Partha, Kornbluth, Sally, Dynlacht, Brian D., Dutta, Anindya · 1996 · Molecular and Cellular Biology
  11. Loss of Rb activates both p53‐dependent and independent cell death pathways in the developing mouse nervous system.
    Macleod, K. F., Hu, Y., Jacks, T. · 1996 · The EMBO Journal
  12. Arsenic trioxide-mediated growth inhibition in MC/CAR myeloma cells via cell cycle arrest in association with induction of cyclin-dependent kinase inhibitor, p21, and apoptosis.
    Woo H. Park, J. G. Seol, Eu-Kyum Kim, Jung Mi Hyun, Chul Won Jung, Chyi‐Chia Richard Lee, Byoung-Kook Kim, Y Y Lee · 2000 · PubMed
  13. A Cyclin-Dependent Kinase Inhibitor, Dacapo, Is Necessary for Timely Exit from the Cell Cycle during Drosophila Embryogenesis
    Joriene C. de Nooij, Mary Ann Letendre, Iswar K. Hariharan · 1996 · Cell
  14. The Guardian's Little Helper: MicroRNAs in the p53 Tumor Suppressor Network
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  15. Mdm4 (Mdmx) regulates p53-induced growth arrest and neuronal cell death during early embryonic mouse development
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  16. Activation and activities of the p53 tumour suppressor protein
    Éva Bálint, Karen H. Vousden · 2001 · British Journal of Cancer
  17. The absence of p21Cip1/WAF1 alters keratinocyte growth and differentiation and promotes ras-tumor progression.
    Caterina Missero, Ferdinando Di Cunto, Hiroaki Kiyokawa, Andrew Koff, Gian Paolo Dotto · 1996 · Genes & Development
  18. Photochemoprevention of ultraviolet B signaling and photocarcinogenesis
    Farrukh Afaq, Vaqar Mustafa Adhami, Hasan Mukhtar · 2005 · Mutation research. Fundamental and molecular mechanisms of mutagenesis
  19. Ubiquitination of p53 and p21 Is Differentially Affected by Ionizing and UV Radiation
    Carl G. Maki, Peter M. Howley · 1997 · Molecular and Cellular Biology
  20. Mechanisms of p53-mediated apoptosis
    Stewart Bates, Karen H. Vousden · 1999 · Cellular and Molecular Life Sciences
  21. Specific loss of apoptotic but not cell‐cycle arrest function in a human tumor derived p53 mutant.
    Sheldon Rowan, R Ludwig, Ygal Haupt, Stewart Bates, Xin Lü, Moshe Oren, Karen H. Vousden · 1996 · The EMBO Journal
  22. Foundations in Cancer Research p53 and ATM: Cell Cycle, Cell Death, and Cancer
    Susan E. Morgan, Michael B. Kastan · 1997 · Advances in cancer research
  23. Functional Collaboration between Different Cyclin-Dependent Kinase Inhibitors Suppresses Tumor Growth with Distinct Tissue Specificity
    David S. Franklin, Virginia Godfrey, Deborah A. O’Brien, Chu‐Xia Deng, Yue Xiong · 2000 · Molecular and Cellular Biology
  24. The Mammalian UV Response
    Eitan Shaulian, Martin Schreiber, Fabrice Piu, Michelle Beeche, Erwin Friedrich Wagner, Michael Karin · 2000 · Cell
  25. Senescence, aging, and malignant transformation mediated by p53 in mice lacking the Brca1 full-length isoform
    Cao, Liu, Li, Wenmei, Kim, Sangsoo, Brodie, Steven G., Deng, Chu-Xia · 2003 · Genes & Development
  26. p53 Efficiently Suppresses Tumor Development in the Complete Absence of Its Cell-Cycle Inhibitory and Proapoptotic Effectors p21, Puma, and Noxa
    Liz J. Valente, Daniel H.D. Gray, Ewa Malgorzata Michalak, Josefina Piñón Hofbauer, Alexander Egle, Clare L. Scott, Ana Janic, Andreas Strasser · 2013 · Cell Reports
  27. The requirement for the p53 proline‐rich functional domain for mediation of apoptosis is correlated with specific PIG3 gene transactivation and with transcriptional repression
    Corinne Venot, Michel Maratrat, Christine Dureuil, Emmanuel Conseiller, Laurent P. Bracco, Laurent Debussche · 1998 · The EMBO Journal
  28. p53 Inhibits Hypoxia-inducible Factor-stimulated Transcription
    Mikhail V. Blagosklonny, Won Gun An, Larisa Y. Romanova, Jane B. Trepel, Tito Fojo, Len Neckers · 1998 · Journal of Biological Chemistry
  29. A Mutant p53 That Discriminates between p53-Responsive Genes Cannot Induce Apoptosis
    Philip Adam Friedlander, Ygal Haupt, Carol L. Prives, Moshe Oren · 1996 · Molecular and Cellular Biology
  30. Inhibition of cyclin-dependent kinase 2 by p21 is necessary for retinoblastoma protein-mediated G 1 arrest after γ-irradiation
    James Brugarolas, Kenneth H. Moberg, Scott Dexter Boyd, Yoichi Taya, Tyler Jacks, Jacqueline A. Lees · 1999 · Proceedings of the National Academy of Sciences
  31. Differential Activation of Target Cellular Promoters by p53 Mutants with Impaired Apoptotic Function
    Robert L. Ludwig, Stewart Bates, Karen H. Vousden · 1996 · Molecular and Cellular Biology
  32. Cell-cycle control and its watchman
    Tyler Jacks, Robert A. Weinberg · 1996 · Nature
  33. Inhibition of the Phosphoinositide 3-Kinase Pathway Induces a Senescence-like Arrest Mediated by p27Kip1
    Manuel Collado, René H. Medema, Isabel Garcı́a-Cao, Marlène Dubuisson, Marta Barradas, Janet Glassford, Carmen Rivas, Boudewijn M.T. Burgering, Manuel Serrano, Eric W.‐F. Lam · 2000 · Journal of Biological Chemistry
  34. Induction of p21WAF1/CIP1/SDI1 in kidney tubule cells affects the course of cisplatin-induced acute renal failure.
    Judit K. Megyesi, Robert L. Safirstein, Peter M. Price · 1998 · Journal of Clinical Investigation
  35. Regulation of p53 responses by post-translational modifications
    Yang Xu · 2003 · Cell Death and Differentiation
  36. Induction of p21 by p53 following DNA damage inhibits both Cdk4 and Cdk2 activities
    Guangan He, Zahid Hussain Siddik, Zai-Feng Huang, Ruoning Wang, John M. Koomen, Ryûji Kobayashi, Abdul R. Khokhar, Jian Kuang · 2005 · Oncogene
  37. Cooperative effects of genes controlling the G2/M checkpoint
    Timothy An-thy Chan, Paul M. Hwang, Heiko Hermeking, Kenneth W. Kinzler, Bert Vogelstein · 2000 · Genes & Development
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    Heiko Müller, Kristian Helin · 2000 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  39. Cell cycle transcription control: DREAM/MuvB and RB-E2F complexes.
    Fischer, Martin, Müller, Gerd A. · 2017 · Critical Reviews in Biochemistry and Molecular Biology
  40. p53 transcriptional activity is essential for p53‐dependent apoptosis following DNA damage
    Connie Chao, Shinichi Saito, Jian Kang, Carl W. Anderson, Ettore Appella, Yang Xu · 2000 · The EMBO Journal
  41. Partial rescue of Brca15–6 early embryonic lethality by p53 or p21 null mutation
    Razqallah Hakem, José Luís de la Pompa, Andrew Elia, Julia Potter, Tak W. Mak · 1997 · Nature Genetics
  42. UV Irradiation Triggers Ubiquitin-Dependent Degradation of p21WAF1 to Promote DNA Repair
    Bendjennat, Mourad, Boulaire, Jérôme, Jascur, Thomas, Brickner, Howard, Barbier, Valerie, Sarasin, Alain, Fotedar, Arun, Fotedar, Rati · 2003 · Cell
  43. Ref‐1 regulates the transactivation and pro‐apoptotic functions of p53 in vivo
    Christian Gaiddon, N.C. Moorthy, C. Prives · 1999 · The EMBO Journal
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    Harrington, Elizabeth A., Bruce, Jacqueline L., Harlow, Ed, Dyson, Nicholas · 1998 · Proceedings of the National Academy of Sciences
  45. Transcriptional activation by p53, but not induction of the p21 gene, is essential for oncogene‐mediated apoptosis.
    Laura Donatella Attardi, Scott W. Lowe, James Brugarolas, Tyler Jacks · 1996 · The EMBO Journal
  46. Polymorphisms in the p53 pathway
    E. Christine Pietsch, Olivier Humbey, Maureen E. Murphy · 2006 · Oncogene
  47. Biology of the cell cycle inhibitor p21CDKN1A: molecular mechanisms and relevance in chemical toxicology
    Ilaria Dutto, Micol Tillhon, Ornella Cazzalini, Lucia Anna Stivala, Ennio Prosperi · 2014 · Archives of Toxicology
  48. Caspase-mediated cleavage of p21Waf1/Cip1 converts cancer cells from growth arrest to undergoing apoptosis
    Yongke Zhang, Naoya Fujita, Takashi Tsuruo · 1999 · Oncogene
  49. Targeted in vivo expression of the cyclin-dependent kinase inhibitor p21 halts hepatocyte cell-cycle progression, postnatal liver development and regeneration.
    Wu, H, Wade, M, Krall, L, Grisham, J, Xiong, Y, Van Dyke, T · 1996 · Genes & Development
  50. Cellular senescence and senescence-associated secretory phenotype via the cGAS-STING signaling pathway in cancer
    Loo, Tze Mun, Miyata, Kenichi, Tanaka, Yoko, Takahashi, Akiko · 2020 · Cancer Science
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    Liang‐Ping Weng · 2001 · Human Molecular Genetics
  52. 3-Hydroxy-3-methylglutaryl CoA reductase inhibitors prevent high glucose-induced proliferation of mesangial cells via modulation of Rho GTPase/ p21 signaling pathway: Implications for diabetic nephropathy
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  53. Arrest of G 1 -S Progression by the p53-Inducible Gene PC3 Is Rb Dependent and Relies on the Inhibition of Cyclin D1 Transcription
    Guardavaccaro, Daniele, Corrente, Giuseppina, Covone, Francesca, Micheli, Laura, D'Agnano, Igea, Starace, Giuseppe, Caruso, Maurizia, Tirone, Felice · 2000 · Molecular and Cellular Biology
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    Alyssa M. Kaiser, Laura Donatella Attardi · 2017 · Cell Death and Differentiation
  55. Clinical implications of p53 mutations
    R. R. Wallace-Brodeur, Scott W. Lowe · 1999 · Cellular and Molecular Life Sciences
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    Karen E. Knudsen, Dana Booth, Soheil Naderi, Zvjezdana Sever-Chroneos, Anne F. Fribourg, Irina C. Hunton, James R. Feramisco, Jean Y. J. Wang, Erik S. Knudsen · 2000 · Molecular and Cellular Biology
  57. Cooperating oncogenes converge to regulate cyclin/cdk complexes.
    Alison C. Lloyd, F Obermüller, S Staddon, Carolyn Frisch Barth, Martin McMahon, Hartmut Land · 1997 · Genes & Development
  58. Cdk2 is dispensable for cell cycle inhibition and tumor suppression mediated by p27Kip1 and p21Cip1
    Alberto Martín, Junko Odajima, Sarah L. Hunt, Pierre R. Dubus, Sagrario Ortega, Marcos Malumbres, Mariano Barbacid · 2005 · Cancer Cell
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    Wojciech Poluha, Dorota K. Poluha, Baochong B. Chang, Nancy E. Crosbie, Christopher M. Schonhoff, Daniel L. Kilpatrick, Alonzo H. Ross · 1996 · Molecular and Cellular Biology
  60. Control of metabolism by p53 – Cancer and beyond
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  66. p53; from inductive signal to cellular effect
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  67. Competing memories of mitogen and p53 signalling control cell-cycle entry
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  69. Lack of p21 expression links cell cycle control and appendage regeneration in mice
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  70. p21Waf1/Cip1/Sdi1 induces permanent growth arrest with markers of replicative senescence in human tumor cells lacking functional p53
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  71. Cip/Kip cyclin-dependent kinase inhibitors: brakes of the cell cycle engine during development
    Keiko Nakayama, Keiko Nakayama · 1999 · BioEssays
  72. Ultraviolet irradiation induces keratinocyte proliferation and epidermal hyperplasia through the activation of the epidermal growth factor receptor
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  74. Murine fibroblasts lacking p21 undergo senescence and are resistant to transformation by oncogenic Ras.
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  82. Life (and death) in a malignant tumour
    Kenneth W. Kinzler, Bert Vogelstein · 1996 · Nature
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  84. Deconstructing p53 transcriptional networks in tumor suppression
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    Lei Zheng, Shang Li, Thomas Boyer, Wen‐Hwa Lee · 2000 · Oncogene
  93. Complicating the complexity of p53
    Karen S.Y. Yee, Karen H. Vousden · 2005 · Carcinogenesis
  94. p53-dependent Induction of PVT1 and miR-1204
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  97. Characterization of Structural p53 Mutants Which Show Selective Defects in Apoptosis but Not Cell Cycle Arrest
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  98. Maintenance of genomic integrity by p53: complementary roles for activated and non-activated p53
    Nils Albrechtsen, Irene Dornreiter, Frank Große, Ella L. Kim, Lisa Wiesmüller, Wolfgang Deppert · 1999 · Oncogene
  99. Biological and clinical importance of the p53 tumor suppressor gene
    Victor E. Velculescu, Wafik S. El‐Deiry · 1996 · Clinical Chemistry
  100. The role of the bcl-2/ced-9 gene family in cancer and general implications of defects in cell death control for tumourigenesis and resistance to chemotherapy
    Andreas Strasser, David C.S. Huang, David Lawrence Vaux · 1997 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer