The DOI matches its Crossref record; 30 of the 31 references it cites were found in a registry or an index.
phot1 and phot2 mediate blue light regulation of stomatal opening
Abstract
The stomatal pores of higher plants allow for gaseous exchange into and out of leaves. Situated in the epidermis, they are surrounded by a pair of guard cells which control their opening in response to many environmental stimuli, including blue light. Opening of the pores is mediated by K(+) accumulation in guard cells through a K(+) channel and driven by an inside-negative electrical potential. Blue light causes phosphorylation and activation of the plasma membrane H(+)-ATPase that creates this potential. Thus far, no blue light receptor mediating stomatal opening has been identified, although the carotenoid, zeaxanthin, has been proposed. Arabidopsis mutants deficient in specific blue-light-mediated responses have identified four blue light receptors, cryptochrome 1 (cry1), cryptochrome 2 (cry2), phot1 and phot2. Here we show that in a double mutant of phot1 and phot2 stomata do not respond to blue light although single mutants are phenotypically normal. These results demonstrate that phot1 and phot2 act redundantly as blue light receptors mediating stomatal opening.
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“Stomatal opening is regulated by the functional redundancy of PHOT1 and PHOT2”
From The action of enhancing weak light capture via phototropic growth and chloroplast movement in plants (2022) · cites this paper as Kinoshita et al., 2001
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Cites
Bradford, M. M. (1976) · Analytical Biochemistry · doi:10.1016/0003-2697(76)90527-3 · Cited by 255,302
Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction
Chomczynski, P., & Sacchi, N. (1987) · Analytical Biochemistry · doi:10.1006/abio.1987.9999 · Cited by 65,515
HY4 gene of A. thaliana encodes a protein with characteristics of a blue-light photoreceptor
Ahmad, M., & Cashmore, A. R. (1993) · Nature · doi:10.1038/366162a0 · Cited by 1,279
G UARD C ELL S IGNAL T RANSDUCTION
Schroeder, J. I., Allen, G. J., Hugouvieux, V., Kwak, J. M., & Waner, D. (2001) · Annual Review of Plant Physiology and Plant Molecular Biology · doi:10.1146/annurev.arplant.52.1.627 · Cited by 1,154
Niyogi, K., Grossman, A. R., & Björkman, O. (1998) · The Plant Cell · doi:10.1105/tpc.10.7.1121 · Cited by 970
Sakai, T., Kagawa, T., Kasahara, M., Swartz, T. E., Christie, J. M., Briggs, W. R., Wada, M., & Okada, K. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.101137598 · Cited by 715
Self-citationArabidopsis NPH1: A Protein Kinase with a Putative Redox-Sensing Domain
Huala, E., Oeller, P. W., Emmanuel Liscum, A., Han, I., Larsen, E., & Briggs, W. R. (1997) · Science · doi:10.1126/science.278.5346.2120 · Cited by 706
Merlot, S., Gosti, F., Guerrier, D., Vavasseur, A., & Giraudat, J. (2001) · The Plant Journal · doi:10.1046/j.1365-313x.2001.00965.x · Cited by 682
Arabidopsis NPL1: A Phototropin Homolog Controlling the Chloroplast High-Light Avoidance Response
Kagawa, T., Sakai, T., Suetsugu, N., Oikawa, K., Ishiguro, S., Kato, T., Tabata, S., Okada, K., & Wada, M. (2001) · Science · doi:10.1126/science.291.5511.2138 · Cited by 651
Self-citationChristie, J. M., Salomon, M., Nozue, K., Wada, M., & Briggs, W. R. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.15.8779 · Cited by 576
Self-citationPhototropin-related NPL1 controls chloroplast relocation induced by blue light
Jarillo, J. A., Gabrys, H., Capel, J., Alonso, J. M., Ecker, J. R., & Cashmore, A. R. (2001) · Nature · doi:10.1038/35073622 · Cited by 476
Kinoshita, T., & Shimazaki, K. (1999) · The EMBO Journal · doi:10.1093/emboj/18.20.5548 · Cited by 452
Self-citationVoltage dependence of K + channels in guard-cell protoplasts
Schroeder, J. I., Raschke, K., & Neher, E. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.12.4108 · Cited by 422
Signal Transduction in Guard Cells
Assmann, S. M. (1993) · Annual Review of Cell Biology · doi:10.1146/annurev.cb.09.110193.002021 · Cited by 412
Blue-Light Photoreceptors in Higher Plants
Briggs, W. R., & Huala, E. (1999) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.15.1.33 · Cited by 395
Blue light activates electrogenic ion pumping in guard cell protoplasts of Vicia faba
Assmann, S. M., Simoncini, L., & Schroeder, J. I. (1985) · Nature · doi:10.1038/318285a0 · Cited by 387
The Phototropin Family of Photoreceptors
Briggs, W. R., Beck, C. F., Cashmore, A. R., Christie, J. M., Hughes, J., Jarillo, J. A., Kagawa, T., Kajiya‐Kanegae, H., Emmanuel Liscum, A., Nagatani, A., et al. (2001) · The Plant Cell · doi:10.1105/tpc.13.5.993 · Cited by 334
Self-citationWillmer, C. M., & Fricker, M. D. (1996) · Springer eBooks · doi:10.1007/978-94-011-0579-8 · Cited by 312
Blue light-dependent proton extrusion by guard-cell protoplasts of Vicia faba
Shimazaki, K., Iino, M., & Zeiger, E. (1986) · Nature · doi:10.1038/319324a0 · Cited by 302
Self-citationBaum, G., Long, J. C., Jenkins, G. I., & TREWAVAS, A. J. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.23.13554 · Cited by 211
Metabolic energy for stomatal opening. Roles of photophosphorylation and oxidative phosphorylation
Schwartz, A., & Zeiger, E. (1984) · Planta · doi:10.1007/bf00395472 · Cited by 186
Fusicoccin: a New Wilting Toxin produced by Fusicoccum amygdali Del.
BALLIO, A., Chain, E. B., Leo, P. D., ERLANGER, B. F., MAURI, M., & TONOLO, A. (1964) · Nature · doi:10.1038/203297a0 · Cited by 177
Zeiger, E., & Zhu, J. (1998) · Journal of Experimental Botany · doi:10.1093/jxb/49.special_issue.433 · Cited by 126
Arabidopsis Contains at Least Four Independent Blue-Light-Activated Signal Transduction Pathways1
Lascève, G., Leymarie, J., Olney, M. A., Emmanuel Liscum, A., Christie, J. M., Vavasseur, A., & Briggs, W. R. (1999) · PLANT PHYSIOLOGY · doi:10.1104/pp.120.2.605 · Cited by 121
Kinetic properties of the blue-light response of stomata
Iino, M., Ogawa, T., & Zeiger, E. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.23.8019 · Cited by 120
Karlsson, P. E. (1986) · Physiologia Plantarum · doi:10.1111/j.1399-3054.1986.tb02410.x · Cited by 82
The Ultraviolet Action Spectrum for Stomatal Opening in Broad Bean
Eisinger, W. R., Swartz, T. E., Bogomolni, R. A., & Taiz, L. (2000) · PLANT PHYSIOLOGY · doi:10.1104/pp.122.1.99 · Cited by 66
Kondo, N., & Sugahara, K. (1978) · Plant and Cell Physiology · doi:10.1093/oxfordjournals.pcp.a075604 · Cited by 61
Light‐induced stomatal movement of selected Arabidopsis thaliana mutants
Eckert, M., & Kaldenhoff, R. (2000) · Journal of Experimental Botany · doi:10.1093/jexbot/51.349.1435 · Cited by 50
Shimazaki, K., Goh, C., & Kinoshita, T. (1999) · Physiologia Plantarum · doi:10.1034/j.1399-3054.1999.105322.x · Cited by 33
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1 of the 31 references couldn’t be matched to a known paper.
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The role of stomata in sensing and driving environmental change
Hetherington, A. M., & Woodward, F. I. (2003) · Nature · doi:10.1038/nature01843 · Cited by 2,468
“Only when both receptor genes in the phot1 , phot2 double mutant are disrupted do the stomata fail to respond to blue ligh”
BackgroundROS and redox signalling in the response of plants to abiotic stress
Suzuki, N., Koussevitzky, S., Mittler, R., & Miller, G. (2011) · Plant Cell & Environment · doi:10.1111/j.1365-3040.2011.02336.x · Cited by 1,700
Light Signal Transduction in Higher Plants
Chen, M., Chory, J., & Fankhauser, C. (2004) · Annual Review of Genetics · doi:10.1146/annurev.genet.38.072902.092259 · Cited by 1,002
“Blue light–driven stomatal opening is also a phototropin-mediated response (98).”
BackgroundPhototropin Blue-Light Receptors
Christie, J. M. (2007) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.58.032806.103951 · Cited by 937
“This response is controlled redundantly by phot1 and phot2, which unlike the situation for phototropism contribute equally to stomatal opening by acting across the same light intensity range (88).”
BackgroundLight Regulation of Stomatal Movement
Shimazaki, K., Doi, M., Assmann, S. M., & Kinoshita, T. (2007) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.57.032905.105434 · Cited by 924
“However, further confirmation is needed because the stomatal aperture responses reported for the npq1 mutant could not be reproduced in leaves, epidermes, or guard cell protoplasts (29, 72, 180).”
BackgroundSelf-citation
Metadata
- Authors
- Kinoshita, T., Doi, M., Suetsugu, N., Kagawa, T., Wada, M., & Shimazaki, K.-I.
- Affiliations
- Kyushu University (JP)
- National Institute for Basic Biology (JP)
- Corresponding author
- Shimazaki, Ken-ichiro
- Venue
- Nature
- Published
- 2001-12
- Volume
- 414
- Issue
- 6864
- Pages
- 656-660
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W2036131768
- Cited by
- 899
- References
- 31
- Citations by year
- 2026: 24 · 2025: 27 · 2024: 45 · 2023: 31 · 2022: 43 · 2021: 42 · 2020: 40 · 2019: 42 · 2018: 40 · 2017: 33 · 2016: 37 · 2015: 34 · 2014: 43 · 2013: 33 · 2012: 42
- FWCI
- 45.17
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature (publishedVersion)
- PubMed (publishedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Light effects on plants
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Photosynthetic Processes and Mechanisms
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Photoreceptor and optogenetics research
- Keywords
- phot1, phot2, blue light receptor, stomatal opening, guard cells, Arabidopsis thaliana, cryptochrome, plasma membrane H+-ATPase, potassium accumulation, zeaxanthin, phototropism
- MeSH terms
- Cell Membrane, Proton-Translocating ATPases, Light, Mutation, Phosphoproteins, Protein Serine-Threonine Kinases, Arabidopsis, Plant Epidermis, Reverse Transcriptase Polymerase Chain Reaction, Arabidopsis Proteins, Photosynthetic Reaction Center Complex Proteins
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