The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.
Policy: NIH to balance sex in cell and animal studies
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“The species, strain, substrain, sex, weight, and age of animals are critical factors that can influence most experimental results [103–107].”
From Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0 (2020) · cites this paper as [103]
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“Multiple longitudinal studies have evaluated whether an interaction exists between sex and AF-related risk of mortality, but the results have not been consistent (Supplementary Table S10).”
From Atrial fibrillation in women: epidemiology, pathophysiology, presentation, and prognosis (2016) · cites this paper as [108]
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Citations
Cites
Sex bias in neuroscience and biomedical research
Beery, A. K., & Zucker, I. (2011) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2010.07.002 · Cited by 1,763
Policy: NIH plans to enhance reproducibility
Collins, F. S., & Tabak, L. A. (2014) · Nature · doi:10.1038/505612a · Cited by 1,247
Self-citationA call for transparent reporting to optimize the predictive value of preclinical research
Landis, S. C., Amara, S. G., Asadullah, K., Austin, C. P., Blumenstein, R., Bradley, E. W., Crystal, R. G., Darnell, R. B., Ferrante, R. J., Fillit, H., et al. (2012) · Nature · doi:10.1038/nature11556 · Cited by 1,196
Strategies and Methods for Research on Sex Differences in Brain and Behavior
Becker, J. B., Arnold, A. P., Berkley, K. J., Blaustein, J. D., Eckel, L. A., Hampson, E., Herman, J. P., Marts, S. A., Sadée, W., Steiner, M. S., et al. (2004) · Endocrinology · doi:10.1210/en.2004-1142 · Cited by 833
Female mice liberated for inclusion in neuroscience and biomedical research
Prendergast, B. J., Onishi, K. G., & Zucker, I. (2014) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2014.01.001 · Cited by 788
Males still dominate animal studies
Zucker, I., & Beery, A. K. (2010) · Nature · doi:10.1038/465690a · Cited by 487
Gender differences in drug responses
Franconi, F., Brunelleschi, S., Steardo, L., & Cuomo, V. (2006) · Pharmacological Research · doi:10.1016/j.phrs.2006.11.001 · Cited by 475
The case for the inclusion of female subjects in basic science studies of pain
Mogil, J. S., & Chanda, M. L. (2005) · Pain · doi:10.1016/j.pain.2005.06.020 · Cited by 376
Innate Gender-based Proclivity in Response to Cytotoxicity and Programmed Cell Death Pathway
Du, L., Bayır, H., Lai, Y., Zhang, X., Kochanek, P. M., Watkins, S. C., Graham, S. H., & Clark, R. S. B. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m405461200 · Cited by 355
The Number of X Chromosomes Causes Sex Differences in Adiposity in Mice
Chen, X., McClusky, R., Chen, J., Beaven, S. W., Tontonoz, P., Arnold, A. P., & Reue, K. (2012) · PLoS Genetics · doi:10.1371/journal.pgen.1002709 · Cited by 326
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Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0
Percie du Sert, N., Ahluwalia, A., Alam, S., Avey, M. T., Baker, M., Browne, W. J., Clark, A., Cuthill, I. C., Dirnagl, U., Emerson, M., et al. (2020) · PLOS Biology · doi:10.1371/journal.pbio.3000411 · Cited by 2,677
Sex and Gender Equity in Research: rationale for the SAGER guidelines and recommended use
Heidari, S., Babor, T. F., De Castro, P., Tort, S., & Curno, M. (2016) · Research Integrity and Peer Review · doi:10.1186/s41073-016-0007-6 · Cited by 2,184
Sex and gender: modifiers of health, disease, and medicine
Mauvais-Jarvis, F., Bairey Merz, N., Barnes, P. J., Brinton, R. D., Carrero, J.-J., DeMeo, D. L., De Vries, G. J., Epperson, C. N., Govindan, R., Klein, S. L., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)31561-0 · Cited by 2,001
Lonardo, A., Nascimbeni, F., Ballestri, S., Fairweather, D., Win, S., Than, T. A., Abdelmalek, M. F., & Suzuki, A. (2019) · Hepatology · doi:10.1002/hep.30626 · Cited by 1,095
Addressing bias in big data and AI for health care: A call for open science
Norori, N., Hu, Q., Aellen, F. M., Faraci, F. D., & Tzovara, A. (2021) · Patterns · doi:10.1016/j.patter.2021.100347 · Cited by 903
Metadata
- Authors
- Clayton, J. A., & Collins, F. S.
- Affiliations
- National Institutes of Health (US)
- Corresponding author
- Clayton, Janine A.
- Venue
- Nature
- Published
- 2014-05
- Volume
- 509
- Issue
- 7500
- Pages
- 282-283
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- PMC
- PMC5101948
- OpenAlex
- W2027431314
- Cited by
- 1,816
- References
- 15
- Citations by year
- 2026: 105 · 2025: 120 · 2024: 142 · 2023: 142 · 2022: 163 · 2021: 162 · 2020: 169 · 2019: 134 · 2018: 141 · 2017: 146 · 2016: 177 · 2015: 151 · 2014: 63
- FWCI
- 178.13
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Sex and Gender in Healthcare
- Social Sciences › Gender Studies › Diversity and Career in Medicine
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health and Medical Research Impacts
- Keywords
- sex differences in research, NIH policy, preclinical research, sex-inclusive research, research funding policy, gender equity in science
- MeSH terms
- Animals, Animals, Laboratory, Cell Line, Disease Models, Animal, Encephalomyelitis, Autoimmune, Experimental, Female, Financing, Organized, Humans, Male, Multiple Sclerosis, National Institutes of Health (U.S.), Neurons, Research Design, Sex Characteristics, Sex Ratio, United States, Peer Review, Research, Substance-Related Disorders, Animal Experimentation, Biomedical Research
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