Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

Shimura, Hideki, Hattori, Nobutaka, Kubo, Shin-ichiro, Mizuno, Yoshikuni, Asakawa, Shuichi, Minoshima, Shinsei, Shimizu, Nobuyoshi, Iwai, Kazuhiro +3 more·2000·Nature Genetics

DOI 10.1038/77060

Cited by (1,004)

Items 301–400 of 1,004

Effect of Wild-type or Mutant Parkin on Oxidative Damage, Nitric Oxide, Antioxidant Defenses, and the Proteasome
Hyun, Dong-Hoon, Lee, MoonHee, Hattori, Nobutaka, Kubo, Shin-Ichiro, Mizuno, Yoshikuni, Halliwell, Barry, Jenner, Peter · 2002 · Journal of Biological Chemistry
Ubiquitin/proteasome pathway impairment in neurodegeneration: therapeutic implications
Qian Huang, Maria E. Figueiredo‐Pereira · 2010 · APOPTOSIS
Rotenone-Induced Model of Parkinson’s Disease: Beyond Mitochondrial Complex I Inhibition
María Teresa Ibarra-Gutiérrez, Norma Serrano‐García, Marisol Orozco‐Ibarra · 2023 · Molecular Neurobiology
A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system
van Wijk, Sjoerd J L, de Vries, Sjoerd J, Kemmeren, Patrick, Huang, Anding, Boelens, Rolf, Bonvin, Alexandre M J J, Timmers, H Th Marc · 2009 · Molecular Systems Biology
The genetics of Parkinson disease: implications for neurological care
Christine Klein, Michael G. Schlossmacher · 2006 · Nature Clinical Practice Neurology
The ubiquitin system: pathogenesis of human diseases and drug targeting
Aaron J. Ciechanover, Alan L. Schwartz · 2004 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Parkin Mono-ubiquitinates Bcl-2 and Regulates Autophagy
Dong Chen, Feng Gao, Bin Li, Hongfeng Wang, Yuxia Xu, Cuiqing Zhu, Guanghui Wang · 2010 · Journal of Biological Chemistry
Update on the genetics of Parkinson's disease
Thomas Gasser · 2007 · Movement Disorders
Parkin and PINK1 functions in oxidative stress and neurodegeneration
Sandeep Kumar Barodia, Rose B. Creed, Matthew S. Goldberg · 2016 · Brain Research Bulletin
p62/ SQSTM1 and Selective Autophagy in Cardiometabolic Diseases
Se‐Jin Jeong, Xiangyu Zhang, Astrid Rodríguez-Vélez, Trent D. Evans, Babak Razani · 2018 · Antioxidants and Redox Signaling
Targeting mitophagy in neurodegenerative diseases
Odetta Antico, Paul W. Thompson, Nicholas T. Hertz, Miratul M. K. Muqit, Laura E. Parton · 2025 · Nature Reviews Drug Discovery
Proteasome inhibition and aggregation in Parkinson's disease: a comparative study in untransfected and transfected cells
Emiliano Biasini, Luana Fioriti, Ilaria Ceglia, Roberto William Invernizzi, Alessandro Bertoli, Roberto Chiesa, Gianluigi Forloni · 2003 · Journal of Neurochemistry
Pink1 Parkinson mutations, the Cdc37/Hsp90 chaperones and Parkin all influence the maturation or subcellular distribution of Pink1
Andreas Weihofen, Beth L. Ostaszewski, Yasufumi Minami, Dennis J. Selkoe · 2007 · Human Molecular Genetics
Milestones in PD genetics
Thomas Gasser, John Hardy, Yoshikuni Mizuno · 2011 · Movement Disorders
Reciprocal Roles of Tom7 and OMA1 during Mitochondrial Import and Activation of PINK1
Shiori Sekine, Chunxin Wang, Dionisia P. Sideris, Eric N. Bunker, Zhe Zhang, Richard J. Youle · 2019 · Molecular Cell
The AMPK–Parkin axis negatively regulates necroptosis and tumorigenesis by inhibiting the necrosome
Seung Baek Lee, Jung Jin Kim, Sang‐Ah Han, Yingfang Fan, Li-Sha Guo, Khaled Aziz, Somaira Nowsheen, Sung Sun Kim, Seon‐Young Park, Qifeng Luo et al. · 2019 · Nature Cell Biology
Protein aggregation in the pathogenesis of familial and sporadic Parkinson's disease
Kevin St. P. McNaught, C. Warren Olanow · 2005 · Neurobiology of Aging
Structural and Functional Insights to Ubiquitin-Like Protein Conjugation
Frederick C. Streich, Christopher D. Lima · 2014 · Annual Review of Biophysics
Oxidation of the cysteine-rich regions of parkin perturbs its E3 ligase activity and contributes to protein aggregation
Fanjun Meng, Dongdong Yao, Yang Shi, Jonathan Kabakoff, Wei Wu, Joshua Jay Reicher, Yuliang Ma, Bernd Moosmann, Eliezer Masliah, Stuart A. Lipton et al. · 2011 · Molecular Neurodegeneration
Associations Among -TrCP, an E3 Ubiquitin Ligase Receptor, -Catenin, and NF- B in Colorectal Cancer
Andrei V. Ougolkov, B. Zhang, K. Yamashita, Vladimir N. Bilim, M Mai, Serge Yu. Fuchs, Toshinari Minamoto · 2004 · JNCI Journal of the National Cancer Institute
Reprint of: Revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease—resemblance to the effect of amphetamine drugs of abuse
Rita Perfeito, Teresa Cunha‐Oliveira, Ana Cristina Rego · 2013 · Free Radical Biology and Medicine
Gene–environment interactions: Key to unraveling the mystery of Parkinson's disease
Hui‐Ming Gao, Jau‐Shyong Hong · 2011 · Progress in Neurobiology
Update on Parkinson Disease
Andrew D. Siderowf, Matthew Stern · 2003 · Annals of Internal Medicine
miR-27a and miR-27b regulate autophagic clearance of damaged mitochondria by targeting PTEN-induced putative kinase 1 (PINK1)
Kim, Jaekwang, Fiesel, Fabienne C., Belmonte, Krystal C., Hudec, Roman, Wang, Wang-Xia, Kim, Chaeyoung, Nelson, Peter T., Springer, Wolfdieter, Kim, Jungsu · 2016 · Molecular Neurodegeneration
Novel mutation in the TOR1A (DYT1) gene in atypical, early onset dystonia and polymorphisms in dystonia and early onset parkinsonism
Joanne Leung, Christine Klein, Jennifer Friedman, P. Vieregge, Helfried Jacobs, Dana O. Doheny, Christoph Kamm, Deborah DeLeon, Peter Paul Pramstaller, John B. Penney et al. · 2001 · Neurogenetics
Pathogenetic mechanisms of parkin in Parkinson's disease
Nobutaka Hattori, Yoshikuni Mizuno · 2004 · The Lancet
Genetic modulation of polyglutamine toxicity by protein conjugation pathways in Drosophila
Ho Yin Edwin Chan · 2002 · Human Molecular Genetics
RING finger 1 mutations in Parkin produce altered localization of the protein
Mark Cookson · 2003 · Human Molecular Genetics
Progression of nigrostriatal dysfunction in a parkin kindred: an [18F]dopa PET and clinical study
Naheed L. Khan · 2002 · Brain
Proteomic analysis of parkin knockout mice: alterations in energy metabolism, protein handling and synaptic function
Magali Periquet, Olga Corti, Sandrine Jacquier, Alexis Brice · 2005 · Journal of Neurochemistry
Mitochondrial Dysfunction in Parkinson's Disease
Jianhui Zhu, Charleen T. Chu · 2010 · Journal of Alzheimer s Disease
Alterations of structure and hydrolase activity of parkinsonism-associated human ubiquitin carboxyl-terminal hydrolase L1 variants
Kaori Nishikawa, Hang Li, Ryoichi Kawamura, Hitoshi Osaka, Yu-Lai Wang, Yoko Hara, Takatsugu Hirokawa, Yoshimasa Manago, Taiju Amano, Mami Noda et al. · 2003 · Biochemical and Biophysical Research Communications
Parkin and the Molecular Pathways of Parkinson's Disease
Benoit I. Giasson, Virginia M.‐Y. Lee · 2001 · Neuron
Increased Oxidative Stress Exacerbates α-Synuclein Aggregation In Vivo
Owen Scudamore, Thomas Ciossek · 2018 · Journal of Neuropathology & Experimental Neurology
Molecular mechanisms of selective dopaminergic neuronal death in Parkinson's disease
Ari Barzilai, Eldad Melamed · 2003 · Trends in Molecular Medicine
Inhibitory effects of pesticides on proteasome activity: Implication in Parkinson's disease
Xuefeng Wang, Sharon Li, Arthur P. Chou, Jeff M. Bronstein · 2006 · Neurobiology of Disease
Genetic basis of Parkinson's disease: inheritance, penetrance, and expression
Thomas Gasser · 2011 · The Application of Clinical Genetics
The NLRP3 Inflammasome is Involved in the Pathogenesis of Parkinson’s Disease in Rats
Mao, Zhijuan, Liu, Chanchan, Ji, Suqiong, Yang, Qingmei, Ye, Hongxiang, Han, Haiyan, Xue, Zheng · 2017 · Neurochemical Research
Parkinson's disease and cancer: two wars, one front
Michael J. Devine, Hélène Plun‐Favreau, Nicholas William Wood · 2011 · Nature reviews. Cancer
Parkin Sensitizes toward Apoptosis Induced by Mitochondrial Depolarization through Promoting Degradation of Mcl-1
Richard G. Carroll, Émilie Hollville, Séamus J. Martin · 2014 · Cell Reports
Protective effect against Parkinson's disease-related insults through the activation of XBP1
Megumi Sado, Yuki Yamasaki, Tomoyuki Iwanaga, Yasushi Onaka, Tatsuki Ibuki, Shigeki Nishihara, Hiroshi Mizuguchi, Hiroshi Momota, Ryuichi Kishibuchi, Tetsuya Hashimoto et al. · 2008 · Brain Research
Evaluation of 50 probands with early-onset Parkinson’s disease for Parkin mutations
Katja Hedrich, Karen S. Marder, Juliette M. Harris, M. Kann, Timothy Lynch, Helen Meija‐Santana, Peter Paul Pramstaller, EBERHARD SCHWINGER, Susan Bressman, Stanley Fahn et al. · 2002 · Neurology
The BAL-binding Protein BBAP and Related Deltex Family Members Exhibit Ubiquitin-Protein Isopeptide Ligase Activity
Kunihiko Takeyama, Ricardo C.T. Aguiar, Liqun Gu, Chunyan He, Gordon James Freeman, Jeffery Lorne Kutok, Jon Christopher Aster, Margaret Ann Shipp · 2003 · Journal of Biological Chemistry
Redox Reactions Induced by Nitrosative Stress Mediate Protein Misfolding and Mitochondrial Dysfunction in Neurodegenerative Diseases
Zezong Gu, Tomohiro Nakamura, Stuart A. Lipton · 2010 · Molecular Neurobiology
Deficiency in ubiquitin ligase TRIM2 causes accumulation of neurofilament light chain and neurodegeneration
Martin Balaštík, Francesco Ferraguti, André Pires‐daSilva, Tae Ho Lee, Gonzalo Álvarez-Bolado, Kun Ping Lu, Peter Gruß · 2008 · Proceedings of the National Academy of Sciences
Association of the Cytoskeletal GTP-binding Protein Sept4/H5 with Cytoplasmic Inclusions Found in Parkinson's Disease and Other Synucleinopathies
Masafumi Ihara, Hidekazu Tomimoto, Hitoshi Kitayama, Yoko Morioka, Ichiro Akiguchi, H. Shibasaki, Makoto Noda, Makoto Kinoshita · 2003 · Journal of Biological Chemistry
The importance of gene dosage studies: mutational analysis of the parkin gene in early-onset parkinsonism
Katja Hedrich · 2001 · Human Molecular Genetics
Parkin and mitochondrial quality control: toward assembling the puzzle
Konstanze F. Winklhofer · 2014 · Trends in Cell Biology
GBA-Associated Parkinson’s Disease and Other Synucleinopathies
Ziv Gan‐Or, Christopher Liong, Roy N. Alcalay · 2018 · Current Neurology and Neuroscience Reports
Role of the ubiquitin proteasome system in Parkinson's disease
Kah‐Leong Lim, Jeanne MM Tan · 2007 · BMC Biochemistry
C. elegans as a model organism to investigate molecular pathways involved with Parkinson's disease
Adam J. Harrington, Shusei Hamamichi, Guy A. Caldwell, Kim A. Caldwell · 2010 · Developmental Dynamics
A Drosophila Model of Mutant Human Parkin-Induced Toxicity Demonstrates Selective Loss of Dopaminergic Neurons and Dependence on Cellular Dopamine
Tzu‐Kang Sang, Hui-Yun Chang, George M. Lawless, Anuradha Ratnaparkhi, Lisa Mee, Larry C. Ackerson, Nigel T. Maidment, David E. Krantz, George R. Jackson · 2007 · Journal of Neuroscience
Hsp70 Gene Transfer by Adeno-associated Virus Inhibits MPTP-Induced Nigrostriatal Degeneration in the Mouse Model of Parkinson Disease
Zhizhong Dong, David Paul Wolfer, Hans‐Peter Lipp, Hansruedi Büeler · 2004 · Molecular Therapy
Pael‐R is accumulated in Lewy bodies of Parkinson's disease
Tetsuro Murakami, Mikio Shoji, Yuzuru Imai, Haruhisa Inoue, Takeshi Kawarabayashi, Etsuro Matsubara, Yasuo Harigaya, Atsushi Sasaki, Ryōsuke Takahashi, Koji Abe · 2004 · Annals of Neurology
Functional ATPase Activity of p97/Valosin-containing Protein (VCP) Is Required for the Quality Control of Endoplasmic Reticulum in Neuronally Differentiated Mammalian PC12 Cells
Taeko Kobayashi, Keiko Tanaka, Kiyoshi Inoue, Akira Kakizuka · 2002 · Journal of Biological Chemistry
Disruption of Protein Quality Control in Parkinson's Disease
Casey N. Cook, Caroline T. Stetler, Leonard Petrucelli · 2012 · Cold Spring Harbor Perspectives in Medicine
Mitochondrial Contribution to Parkinson's Disease Pathogenesis
Anthony H.V. Schapira, Matthew E. Gegg · 2011 · Parkinson s Disease
RBR E3‐ligases at work
Judith J. Smit, Titia K. Sixma · 2014 · EMBO Reports
Genome Patterns of Selection and Introgression of Haplotypes in Natural Populations of the House Mouse (Mus musculus)
Fabian Staubach, Anna Lorenc, Philipp W. Messer, Kun Tang, Dmitri A. Petrov, Diethard Tautz · 2012 · PLoS Genetics
Emerging pathways to neurodegeneration: Dissecting the critical molecular mechanisms in Alzheimer’s disease, Parkinson’s disease
Sean Hong Tan, Venkatanaidu Karri, Nicole Wuen Rong Tay, Kuan Hui Chang, Hui Yen Ah, Phui Qi Ng, Hui San Ho, Hsiao Wai Keh, Mayuren Candasamy · 2019 · Biomedicine & Pharmacotherapy
Proteasomal inhibition causes the formation of protein aggregates containing a wide range of proteins, including nitrated proteins
Dong‐Hoon Hyun, MoonHee Lee, Barry B. Halliwell, Peter G. Jenner · 2003 · Journal of Neurochemistry
The Machado–Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability
Thomas M. Durcan, Maria Kontogiannea, Thorhildur Thorarinsdottir, Lara Fallon, Aislinn Joanmarie Williams, Ana Djarmati, Tadeu A. Fantaneanu, Henry Lauris Paulson, Edward A. Fon · 2010 · Human Molecular Genetics
Parkin-mediated lysine 63-linked polyubiquitination: A link to protein inclusions formation in Parkinson's and other conformational diseases?
Kah‐Leong Lim, Valina Lynn Dawson, Ted M. Dawson · 2005 · Neurobiology of Aging
Parkin Accumulation in Aggresomes Due to Proteasome Impairment
Eunsung Junn, Sang Seop Lee, Unsun T. Suhr, M. Maral Mouradian · 2002 · Journal of Biological Chemistry
A molecular explanation for the recessive nature of parkin-linked Parkinson’s disease
Donald E. Spratt, R.J. Martinez-Torres, Yeong Ju Noh, Pascal Mercier, Noah Manczyk, Kathryn R. Barber, Jacob D. Aguirre, Lynn Burchell, Andrew G. Purkiss, Helen Walden et al. · 2013 · Nature Communications
What causes cell death in Parkinson's disease?
Amitabh Gupta, Valina Lynn Dawson, Ted M. Dawson · 2009 · Annals of Neurology
Molecular mechanism of the relation of monoamine oxidase B and its inhibitors to Parkinson’s disease: possible implications of glial cells
Toshiharu Nagatsu, Makoto Sawada · 2006 · Springer eBooks
RING-Between-RING E3 Ligases: Emerging Themes amid the Variations
Katja K. Dove, Rachel E. Klevit · 2017 · Journal of Molecular Biology
Inactivation of Parkin by Oxidative Stress and C-terminal Truncations
Konstanze F. Winklhofer, Iris H. Henn, Penelope C. Kay-Jackson, Ulrich Heller, Jörg Tatzelt · 2003 · Journal of Biological Chemistry
Ubiquitin-proteasome-mediated local protein degradation and synaptic plasticity
Ashok N. Hegde · 2004 · Progress in Neurobiology
Identification of a Novel Zn2+-binding Domain in the Autosomal Recessive Juvenile Parkinson-related E3 Ligase Parkin
Ventzislava A. Hristova, Steven Beasley, Rebecca Jane Rylett, Gary S. Shaw · 2009 · Journal of Biological Chemistry
Elevated Neuronal Expression of CD200 Protects Wlds Mice from Inflammation-Mediated Neurodegeneration
Tanuja Chitnis, Jaime Imitola, Yue Wang, Wassim Elyaman, Prianka Chawla, Maia Sharuk, Khadir Raddassi, Roderick Terry Bronson, Samia Joseph Khoury · 2007 · American Journal Of Pathology
Oxidative modifications, mitochondrial dysfunction, and impaired protein degradation in Parkinson's disease: how neurons are lost in the Bermuda triangle
Kristen A. Malkus, Elpida Tsika, Harry Ischiropoulos · 2009 · Molecular Neurodegeneration
An inhibitor of mitochondrial complex I, rotenone, inactivates proteasome by oxidative modification and induces aggregation of oxidized proteins in SH‐SY5Y cells
Masayo Shamoto‐Nagai, Wakako Maruyama, Yoji Kato, Ken‐ichi Isobe, Masashi Tanaka, Makoto Naoi, Toshihiko Osawa · 2003 · Journal of Neuroscience Research
The PINK1–Parkin axis: An Overview
Keiji Tanaka · 2020 · Neuroscience Research
Mitochondrial dynamics in Parkinson's disease
Victor S. Van Laar, Sarah Berman · 2009 · Experimental Neurology
Genetics of parkinsonism
Katrina A. Gwinn · 2002 · Movement Disorders
Parkinson's disease: piecing together a genetic jigsaw
Marieke Cornelia Johanna Dekker · 2003 · Brain
Role of parkin mutations in 111 community‐based patients with early‐onset parkinsonism
Martin Kann, Helfried Jacobs, K. Mohrmann, Kirsten Schumacher, Katja Hedrich, Jennifer Garrels, Karin Wiegers, EBERHARD SCHWINGER, Peter Paul Pramstaller, Xandra O. Breakefield et al. · 2002 · Annals of Neurology
A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson's disease
Peter Holmans, Valentina Moskvina, Lesley Jones, Manu Sharma, Alexey Vedernikov, Finja Büchel, Mohamad Sadd, José Brás, Francesco Bettella, Nayia Nicolaou et al. · 2012 · Human Molecular Genetics
Phosphorylation of Parkin at Serine65 is essential for activation: elaboration of a Miro1 substrate-based assay of Parkin E3 ligase activity
Agne Kazlauskaite, Van C. Kelly, Clare Johnson, Carla Baillie, C. James Hastie, Mark W. Peggie, Thomas Macartney, Helen I. Woodroof, Dario R. Alessi, Patrick G. A. Pedrioli et al. · 2014 · Open Biology
Back to the tubule: microtubule dynamics in Parkinson’s disease
Laura Pellegrini, Andrea Wetzel, Simone Grannò, George Heaton, Kirsten Harvey · 2016 · Cellular and Molecular Life Sciences
Parkin Ubiquitinates Tar-DNA Binding Protein-43 (TDP-43) and Promotes Its Cytosolic Accumulation via Interaction with Histone Deacetylase 6 (HDAC6)
Michaeline L. Hebron, Irina Lonskaya, Kaydee Sharpe, Puwakdandawe P.K. Weerasinghe, Norah Khaled Algarzae, Ashot R. Shekoyan, Charbel Moussa · 2012 · Journal of Biological Chemistry
SH3 Domains from a Subset of BAR Proteins Define a Ubl-Binding Domain and Implicate Parkin in Synaptic Ubiquitination
Jean‐François Trempe, Carol X.‐Q. Chen, Karl Grenier, Edna Matta‐Camacho, Guennadi Kozlov, Peter Scottt McPherson, Kalle Gehring, Edward A. Fon · 2009 · Molecular Cell
Mitochondrial quality control in acute ischemic stroke
Hong An, Bing Zhou, Xunming Ji · 2021 · Journal of Cerebral Blood Flow & Metabolism
Ubiquitination of α-Synuclein Is Not Required for Formation of Pathological Inclusions in α-Synucleinopathies
Deepak M. Sampathu, Benoit I. Giasson, Aaron C. Pawlyk, John Q. Trojanowski, Virginia M.‐Y. Lee · 2003 · American Journal Of Pathology
Review: Familial Parkinson's disease – genetics, clinical phenotype and neuropathology in relation to the common sporadic form of the disease
Carola Schiesling, Nicole Kieper, Kay Seidel, Rejko Krüger · 2008 · Neuropathology and Applied Neurobiology
Linking DJ-1 to neurodegeneration offers novel insights for understanding the pathogenesis of Parkinson?s disease
Vincenzo Bonifati, Ben A. Oostra, Peter Heutink · 2004 · Journal of Molecular Medicine
Parkinson Disease from Mendelian Forms to Genetic Susceptibility: New Molecular Insights into the Neurodegeneration Process
Amin Karimi Moghadam, Saeid Charsouei, Benjamin Bell, Mohammad Reza Jabalameli · 2018 · Cellular and Molecular Neurobiology
Spongiform Neurodegeneration-associated E3 Ligase Mahogunin Ubiquitylates TSG101 and Regulates Endosomal Trafficking
Bong Yoon Kim, James A. Olzmann, Gregory S. Barsh, Lih‐Shen Chin, Lian Li · 2007 · Molecular Biology of the Cell
Ubiquitin pathways in neurodegenerative disease
Graham Atkin, Henry Lauris Paulson · 2014 · Frontiers in Molecular Neuroscience
M itochondrial DNA and primary mitochondrial dysfunction in P arkinson's disease
Maria Pia Giannoccaro, Chiara La Morgia, Giovanni Rizzo, Valério Carelli · 2017 · Movement Disorders
Parkin is associated with cellular vesicles
Shinichiro Kubo, Toshiaki Kitami, Setsuko Noda, Hideki Shimura, Yasuo Uchiyama, Shuichi Asakawa, Shinsei Minoshima, Nobuyoshi Shimizu, Yoshikuni Mizuno, Nobutaka Hattori · 2001 · Journal of Neurochemistry
Spongiform Degeneration in mahoganoid Mutant Mice
Lin He, Xin‐Yun Lu, Aaron F. Jolly, Adam G. Eldridge, Stanley J. Watson, Peter K. Jackson, Gregory S. Barsh, Teresa M. Gunn · 2003 · Science
Parkin-mediated Monoubiquitination of the PDZ Protein PICK1 Regulates the Activity of Acid-sensing Ion Channels
Monica Joch, Ariel R. Ase, Carol X.‐Q. Chen, Penny A. MacDonald, Maria Kontogiannea, Amadou Tidjane Corera, Alexis Brice, Philippe Séguéla, Edward A. Fon · 2007 · Molecular Biology of the Cell
Mitochondria, calcium, and endoplasmic reticulum stress in Parkinson's disease
Tito Calí, Denis Ottolini, Marisa Brini · 2011 · BioFactors
Mechanistic Approaches to Parkinson's Disease Pathogenesis
Ranjita S. Betarbet, Todd Sherer, Donato A. Di Monte, J. Timothy Greenamyre · 2002 · Brain Pathology
Structure and Function of Parkin, PINK1, and DJ-1, the Three Musketeers of Neuroprotection
Jean‐François Trempe, Edward A. Fon · 2013 · Frontiers in Neurology
Traffic at the intersection of neurotrophic factor signaling and neurodegeneration
Salehi, Ahmad, Delcroix, Jean-Dominique, Mobley, William C. · 2003 · Trends in Neurosciences
How does parkin ligate ubiquitin to Parkinson's disease?
Philipp J. Kahle, Christian Haass · 2004 · EMBO Reports