Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

Shimura, Hideki, Hattori, Nobutaka, Kubo, Shin-ichiro, Mizuno, Yoshikuni, Asakawa, Shuichi, Minoshima, Shinsei, Shimizu, Nobuyoshi, Iwai, Kazuhiro +3 more·2000·Nature Genetics
DOI 10.1038/77060

Cited by (1,004)

Items 401–500 of 1,004

  1. Microtubule Dysfunction: A Common Feature of Neurodegenerative Diseases
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  2. Parkin-associated Parkinson’s disease
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  3. Impaired dopamine release and synaptic plasticity in the striatum of <i>Parkin</i>−/− mice
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  4. New implications for the QUAKING RNA binding protein in human disease
    Carol Anne Chénard, Stéphane Richard · 2007 · Journal of Neuroscience Research
  5. Parkin variants in North American Parkinson's disease: Cases and controls
    Sarah Lincoln, Demetrius M. Maraganore, Timothy G. Lesnick, Rebecca Bounds, Mariza de Andrade, James H. Bower, John Hardy, Matthew James Farrer · 2003 · Movement Disorders
  6. Mechanism of neurodegenerative disease: role of the ubiquitin proteasome system
    Leonardo Petrucelli, Ted M. Dawson · 2004 · Annals of Medicine
  7. Protein misfolding in Alzheimer’s and Parkinson’s disease: genetics and molecular mechanisms
    Gianluigi Forloni, Liana Terreni, Ilaria Bertani, Sergio Fogliarino, Roberto William Invernizzi, Andrea Assini, Giuseppe Ribizzi, Alessandro Negro, Elena Calabrese, Maria Antonietta Volonté · 2002 · Neurobiology of Aging
  8. The utility F-box for protein destruction
    Margaret Su-chun Ho, Chan-Yen Ou, Y. Chan, Cheng‐Ting Chien, Haiwei Pi · 2008 · Cellular and Molecular Life Sciences
  9. Pruning and loss of excitatory synapses by the parkin ubiquitin ligase
    Thomas D. Helton, Takeshi Otsuka, Ming-Chia Lee, Yuanyue Mu, Michael Ehlers · 2008 · Proceedings of the National Academy of Sciences
  10. Proteasomal Inhibition-Induced Inclusion Formation and Death in Cortical Neurons Require Transcription and Ubiquitination
    Hardy J. Rideout, Leonidas Stefanis · 2002 · Molecular and Cellular Neuroscience
  11. parkin counteracts symptoms in a Drosophila model of Parkinson's disease
    Annika F.M. Haywood, Brian E. Staveley · 2004 · BMC Neuroscience
  12. Manganese-Induced Dopaminergic Neurodegeneration: Insights into Mechanisms and Genetics Shared with Parkinson’s Disease
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  13. UCH‐L1 aggresome formation in response to proteasome impairment indicates a role in inclusion formation in Parkinson's disease
    H.C. Ardley, Gina B. Scott, Stephen A. Rose, Nancy G. S. Tan, Philip Alan Robinson · 2004 · Journal of Neurochemistry
  14. Cdk5: Multitasking between physiological and pathological conditions
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  15. DJ-1 and Parkin Modulate Dopamine-dependent Behavior and Inhibit MPTP-induced Nigral Dopamine Neuron Loss in Mice
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  16. Fibroblast Growth Factor (FGF)-2 and FGF Receptor 3 Are Required for the Development of the Substantia Nigra, and FGF-2 Plays a Crucial Role for the Rescue of Dopaminergic Neurons after 6-Hydroxydopamine Lesion
    M. Timmer, K. Cesnulevicius, C. Winkler, J. Kolb, E. Lipokatic-Takacs, Julia Jungnickel, C. Grothe · 2007 · Journal of Neuroscience
  17. 14‐3‐3η is a novel regulator of parkin ubiquitin ligase
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  18. Genetics of Parkinson disease
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  19. Rapid Ca 2+ -dependent decrease of protein ubiquitination at synapses
    Hong Chen, Simona Polo, Pier Paolo Di Fiore, Pietro V. De Camilli · 2003 · Proceedings of the National Academy of Sciences
  20. Effect of endogenous mutant and wild-type PINK1 on Parkin in fibroblasts from Parkinson disease patients
    Aleksandar Raković, Anne Grünewald, Philip Seibler, Alfredo Ramı́rez, Norman Kock, Slobodanka Orolicki, Katja Lohmann, Christine Klein · 2010 · Human Molecular Genetics
  21. Dopamine-dependent neurodegeneration in rats induced by viral vector-mediated overexpression of the parkin target protein, CDCrel-1
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  22. SEPT5_v2 is a parkin-binding protein
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  23. Parkin and Parkinsonʼs disease
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  24. Phosphorylated tau and the neurodegenerative foldopathies
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  25. Behavioral Phenotyping of Parkin-Deficient Mice: Looking for Early Preclinical Features of Parkinson's Disease
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  26. Phosphorylation of Parkin by the Cyclin-dependent Kinase 5 at the Linker Region Modulates Its Ubiquitin-Ligase Activity and Aggregation
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  27. Cellular and Molecular Mechanisms of Parkinson’s Disease: Neurotoxins, Causative Genes, and Inflammatory Cytokines
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  29. Parkin Increases Dopamine Uptake by Enhancing the Cell Surface Expression of Dopamine Transporter
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  30. Mitochondrial DNA : more than an evolutionary bystander
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  31. Parkin Regulates the Activity of Pyruvate Kinase M2
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  32. Alterations in the solubility and intracellular localization of parkin by several familial Parkinson's disease‐linked point mutations
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  33. To die or grow: Parkinson's disease and cancer
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  34. Inhibition of Proteasomal Activity Causes Inclusion Formation in Neuronal and Non-Neuronal Cells Overexpressing Parkin
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  43. Identification of a Novel Gene Linked to Parkin via a Bi-directional Promoter
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  44. Pael receptor induces death of dopaminergic neurons in the substantia nigra via endoplasmic reticulum stress and dopamine toxicity, which is enhanced under condition of parkin inactivation
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  54. Biomarkers of neurodegenerative disorders: How good are they?
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  55. Heterozygous parkin point mutations are as common in control subjects as in Parkinson's patients
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  56. Parkinson disease: etiology, pathogenesis and future of gene therapy
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  57. Parkin-positive autosomal recessive juvenile parkinsonism with α-synuclein-positive inclusions
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  58. Parkin and relatives: the RBR family of ubiquitin ligases
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  59. Parkin
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  60. Parkin attenuates manganese‐induced dopaminergic cell death
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  61. Proteasome Mediates Dopaminergic Neuronal Degeneration, and Its Inhibition Causes α-Synuclein Inclusions
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  62. Neuroprotective Function of 14-3-3 Proteins in Neurodegeneration
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  65. A Caenorhabditis elegans Parkin mutant with altered solubility couples α-synuclein aggregation to proteotoxic stress
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  67. Parkin mutations reduce the complexity of neuronal processes in iPSC-derived human neurons
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  70. Non‐motor behavioural impairments in parkin‐deficient mice
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  75. Genetics of Parkinson's disease.
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  97. Revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease—resemblance to the effect of amphetamine drugs of abuse
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