DAP12 signaling: from immune cells to bone modeling and brain myelination

Bone Resorption by Osteoclasts

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Bone versus immune system

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Mutations in Two Genes Encoding Different Subunits of a Receptor Signaling Complex Result in an Identical Disease Phenotype

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Osteopetrosis and thalamic hypomyelinosis with synaptic degeneration in DAP12-deficient mice

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DAP12-deficient mice fail to develop autoimmunity due to impaired antigen priming.

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DAP12-mediated Signal Transduction in Natural Killer Cells

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Gene Structure, Expression Pattern, and Biological Activity of Mouse Killer Cell Activating Receptor-associated Protein (KARAP)/DAP-12*

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From Neural Stem Cells to Myelinating Oligodendrocytes

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Combined Natural Killer Cell and Dendritic Cell Functional Deficiency in KARAP/DAP12 Loss-of-Function Mutant Mice

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Heterogeneity of presenile dementia with bone cysts (Nasu–Hakola disease)

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Role of neuroinflammation in neurodegeneration development

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Osteoimmunology: Interactions of the Bone and Immune System

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Neurodegenerative disease mutations in TREM2 reveal a functional surface and distinct loss-of-function mechanisms

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Bone modeling: biomechanics, molecular mechanisms, and clinical perspectives

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The extended human leukocyte receptor complex: diverse ways of modulating immune responses

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What is microglia neurotoxicity (Not)?

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The brain’s best friend: microglial neurotoxicity revisited

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Macrophages Expressing Triggering Receptor Expressed on Myeloid Cells-1 Are Underrepresented in the Human Intestine

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TYROBP in Alzheimer’s Disease

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SIGLEC16 encodes a DAP12‐associated receptor expressed in macrophages that evolved from its inhibitory counterpart SIGLEC11 and has functional and non‐functional alleles in humans

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Structure, expression pattern and biological activity of molecular complex TREM-2/DAP12

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Microglial Immunoreceptor Tyrosine-Based Activation and Inhibition Motif Signaling in Neuroinflammation

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The Triggering Receptor Expressed on Myeloid Cells 2: A Molecular Link of Neuroinflammation and Neurodegenerative Diseases

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The TREM2-DAP12 signaling pathway in Nasu–Hakola disease: a molecular genetics perspective

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RNA-Seq analysis implicates dysregulation of the immune system in schizophrenia

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Brain Innate Immunity in the Regulation of Neuroinflammation: Therapeutic Strategies by Modulating CD200-CD200R Interaction Involve the Cannabinoid System

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Fugu rubripes possesses genes for the entire set of the ITAM-bearing transmembrane signal subunits

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Mapping and kinetics of microglia/neuron cell-to-cell contacts in the 6-OHDA murine model of Parkinson's disease

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TREM2 mRNA Expression in Leukocytes Is Increased in Alzheimer’s Disease and Schizophrenia

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T-cell involvement in osteoclast biology: implications for rheumatoid bone erosion

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Single Cell Transcriptome Analysis of Niemann–Pick Disease, Type C1 Cerebella

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The facial motor nucleus transcriptional program in response to peripheral nerve injury identifies Hn1 as a regeneration‐associated gene

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Skeletal interoception and prospective application in biomaterials for bone regeneration

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Synaptic pruning by microglia: lessons from genetic studies in mice

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A reporter cell system for the triggering receptor expressed on myeloid cells 2 reveals differential effects of disease‐associated variants on receptor signaling and activation by antibodies against the stalk region

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Current understanding on TREM-2 molecular biology and physiopathological functions

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Serine/threonine phosphatases in osteoclastogenesis and bone resorption

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Understanding Microglia–Neuron Cross Talk: Relevance of the Microglia–Neuron Cocultures

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DAP12 interacts with RER1 and is retained in the secretory pathway before assembly with TREM2

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Osteopetroses and immunodeficiencies in humans

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Therapeutic radiation exposure of the abdomen during childhood induces chronic adipose tissue dysfunction

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Double-stranded RNA analog and type I interferon regulate expression of Trem paired receptors in murine myeloid cells

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Gene expression analysis of bromine-induced burns in porcine skin☆

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Unveiling the impact of TREM-2+ Macrophages in metabolic disorders

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Immune cells and bone: coupling goes both ways

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Osteoclast Precursor Cells

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The microglial innate immune receptor TREM2 participates in fear memory formation through excessive prelimbic cortical synaptic pruning

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Prostaglandins and Proinflammatory Cytokines

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Dynamic gene expression analysis reveals distinct severity phases of immune and cellular dysregulation in COVID-19Preprint

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Longitudinal gene expression analysis in COVID-19 sepsis highlights dynamic immune, cellular, and metabolic dysfunction in high severity patients

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Microglial TDP-43 mediates myelin refinement and represses Tyrobp cryptic exon inclusion in mice

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Cloning and Characterization of DAP10 homologue gene from Olive Flounder, Paralichthys olivaceus

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Estudo dos mecanismos genéticos e celulares durante a fase inflamatória do processo de regeneração tecidual em animais selecionados geneticamente para a máxima resposta inflamatória aguda homozigotos para os alelos R ou S do gene Slc11a1.

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Identification of Immune Activation-Related Biomarkers in Acute Myocardial Infarction (AMI) by Bioinformatic Analysis and Clinical ValidationPreprint

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Identification of marophage-related biomarkers in acute myocardial infarction (AMI) by bioinformatic analysis and clinical validationPreprint

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Contrôle de l'activation microgliale par les lymphocytes T dans un modèle murin de neurodégénérescence induite par la 6-OHDA

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Retention of duplicated ITAM-containing transmembrane signaling subunits in the tetraploid amphibian species Xenopus laevis

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The TREM2-DAP12 signaling pathway in Nasu–Hakola disease: a molecular genetics perspective

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Brain and Bone Damage in KARAP/DAP12 Loss-of-Function Mice Correlate with Alterations in Microglia and Osteoclast Lineages

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Pathogenic mechanisms of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL)

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DAP12/TREM2 deficiency results in impaired osteoclast differentiation and osteoporotic features

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Brief Definitive Report DAP12/TREM2 Deficiency Results in Impaired Osteoclast Differentiation and Osteoporotic Features

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