The DOI matches its Crossref record; 58 of the 58 references it cites were found in a registry or an index.
The ubiquitin system
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Citations
Cites
Hershko, A., & Ciechanover, A. (1998) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.67.1.425 · Cited by 8,840
Self-citationThe E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
Scheffner, M., Werness, B. A., Huibregtse, J. M., Levine, A. J., & Howley, P. M. (1990) · Cell · doi:10.1016/0092-8674(90)90409-8 · Cited by 3,995
Cyclin is degraded by the ubiquitin pathway
Glotzer, M., Murray, A. W., & Kirschner, M. W. (1991) · Nature · doi:10.1038/349132a0 · Cited by 2,357
In Vivo Half-Life of a Protein Is a Function of Its Amino-Terminal Residue
Bachmair, A., Finley, D., & Varshavsky, A. (1986) · Science · doi:10.1126/science.3018930 · Cited by 1,971
Self-citationA multiubiquitin chain is confined to specific lysine in a targeted short-lived protein
Chau, V., Tobias, J. W., Bachmair, A., Marriott, D., Ecker, D. J., Gonda, D. K., & Varshavsky, A. (1989) · Science · doi:10.1126/science.2538923 · Cited by 1,535
Self-citationHershko, A., Heller, H., Elias, S., & Ciechanover, A. (1983) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(20)82050-x · Cited by 1,160
Self-citationThe N-end rule: functions, mysteries, uses
Varshavsky, A. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.22.12142 · Cited by 859
Self-citationUbiquitin-mediated proteolysis: biological regulation via destruction
Ciechanover, A., Orian, A., & Schwartz, A. L. (2000) · BioEssays · doi:10.1002/(sici)1521-1878(200005)22:5<442::aid-bies6>3.0.co;2-q · Cited by 853
Self-citationFinley, D., Özkaynak, E., & Varshavsky, A. (1987) · Cell · doi:10.1016/0092-8674(87)90711-2 · Cited by 851
Self-citationA Proteolytic Pathway That Recognizes Ubiquitin as a Degradation Signal
Johnson, E. S., Ma, P. C. M., Ota, I. M., & Varshavsky, A. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.29.17442 · Cited by 821
Self-citation
Cited by
The SCF ubiquitin ligase: insights into a molecular machine
Cardozo, T., & Pagano, M. (2004) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1471 · Cited by 1,114
Drug discovery in the ubiquitin–proteasome system
Nalepa, G., Rolfe, M., & Harper, J. W. (2006) · Nature Reviews Drug Discovery · doi:10.1038/nrd2056 · Cited by 608
CHIP is a chaperone‐dependent E3 ligase that ubiquitylates unfolded protein
Murata, S., Minami, Y., Minami, M., Chiba, T., & Tanaka, K. (2001) · The EMBO Reports · doi:10.1093/embo-reports/kve246 · Cited by 574
THE ESCRT COMPLEXES: Structure and Mechanism of a Membrane-Trafficking Network
Hurley, J. H., & Emr, S. D. (2006) · Annual Review of Biophysics and Biomolecular Structure · doi:10.1146/annurev.biophys.35.040405.102126 · Cited by 546
N-degron and C-degron pathways of protein degradation
Varshavsky, A. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1816596116 · Cited by 544
Self-citation
Metadata
- Authors
- Hershko, A., Ciechanover, A., & Varshavsky, A.
- Venue
- Nature Medicine
- Published
- 2000-10
- Volume
- 6
- Issue
- 10
- Pages
- 1073-1081
- ISSN
- 1078-8956 (ISSN-L)
- 1546-170X
- OpenAlex
- W1851733051
- Cited by
- 649
- References
- 58
- FWCI
- 7.77
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: The ubiquitin system. https://app.cochat.ai/papers/10.1038/80384
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- Hershko, A., Ciechanover, A., & Varshavsky, A. (2000). The ubiquitin system. Nature Medicine. https://doi.org/10.1038/80384
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
