Regulation of AMPA receptor endocytosis by a signaling mechanism shared with LTD

Beattie, Eric C.; Carroll, Reed C.; Yu, Xiang; Morishita, Wade; Yasuda, Hiroki; von Zastrow, Mark; Malenka, Robert C.

doi:10.1038/81823

Regulation of AMPA receptor endocytosis by a signaling mechanism shared with LTD

The endocytosis of AMPA receptors is thought to be important in the expression of long-term depression (LTD) triggered by NMDA receptor activation. Although signaling pathways necessary for LTD induction have been identified, those responsible for the regulated internalization of AMPA receptors a…