The NOD mouse model of type 1 diabetes: As good as it gets?

Atkinson, Mark A., Leiter, Edward H.·1999·Nature Medicine
DOI 10.1038/9442

Cited by (593)

Items 401–500 of 593

  1. Stem cell therapies for type 1 diabetes mellitus.
    J C Voltarelli, Carlos Eduardo Barra Couri, Maria C Rodrigues, Daniela A. Moraes, A.P. Stracieri, Fabiano Pieroni, George Navarro, Angela M. O. Leal, Belinda Pinto Simões · 2011 · PubMed
  2. 2α-Methyl-19-nor-(20S)-1,25-dihydroxyvitamin D3 protects the insulin 2 knockout non-obese diabetic mouse from developing type 1 diabetes without hypercalcaemia
    Carol M. Kiekhaefer, B Weber, Margaret M. Huggins, C Gorichanaz, Jamie A. Nehring, Hector F. Deluca · 2011 · Clinical & Experimental Immunology
  3. Deviation of islet autoreactivity to cryptic epitopes protects NOD mice from diabetes
    Aihua Song, Shawn Winer, Hubert Tsui, Anastazia Sampson, Peter Pasceri, James Ellis, John F. Elliott, H.‐Michael Dosch · 2003 · European Journal of Immunology
  4. Inhibition of Autoimmune Diabetes in NOD Mice by miRNA Therapy
    Duncheng Wang, Iryna Shanina, Wendy M. Toyofuku, Marc Steven Horwitz, Mark D. Scott · 2015 · PLoS ONE
  5. Infant Feeding and Autoimmune Diabetes
    Hans‐Michael Dosch, DOROTHY J. BECKER · 2002 · Advances in experimental medicine and biology
  6. HLA-DQ8 Supports Development of Insulitis Mediated by Insulin-Reactive Human TCR-Transgenic T Cells in Nonobese Diabetic Mice
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  7. The Potential Role of Dendritic Cells in the Therapy of Type 1 Diabetes
    Chin‐Nien Lee, Andrew M. Lew, Li Wu · 2013 · Immunotherapy
  8. The role of STAT3 in antigen-IgG inducing regulatory CD4+Foxp3+T cells
    Renxi Wang, Gencheng Han, Jianan Wang, Lun Song, Guojiang Chen, Ruonan Xu, Ming Yu, Jiahua Qian, Beifen Shen, Yan Li · 2007 · Cellular Immunology
  9. Drugs from the Sea: A Marine Sponge-Derived Compound Prevents Type 1 Diabetes
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  10. MCS-18, a novel natural plant product prevents autoimmune diabetes
    C. Seifarth, Leonie Littmann, Yazid J. Resheq, Susanne Rößner, Andreas Goldwich, Nadine Pangratz, F Kerek, Alexander Steinkasserer, Elisabeth Zinser · 2011 · Immunology Letters
  11. Type 1 Diabetes Prevention in NOD Mice by Targeting DPPIV/CD26 Is Associated with Changes in CD8+T Effector Memory Subset
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  12. Diverse Routes of Allograft Tolerance Disruption by Memory T Cells
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  13. Small things matter: Lack of extra-islet beta cells in Type 1 diabetes
    Kathryn Murrall, Teifion Luckett, Christiana Lekka, Christine S. Flaxman, Rebecca C. Wyatt, Pouria Akhbari, Irina Kusmartseva, Stephanie L. Hunter, Pia Leete, Isabel Burn et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  14. Dental erosion in mice with impaired salivary gland function
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  15. Elevated glucagon-like peptide-1 plasma levels, as a possible adaptive response, in diabetic NOD mice
    Tobias Rydgren, A. Börjesson, A. Carlsson, S. Sandler · 2012 · Biochemical and Biophysical Research Communications
  16. Timing of Immunotherapy in Type 1 Diabetes: The Earlier, the Better?
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  17. Gene Expression of Catalytic Proteasome Subunits and Resistance Toward Proteasome Inhibition of B Lymphocytes from Patients with Primary Sjögren Syndrome
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  18. Quantification of chemokines by real-time reverse transcriptase PCR: applications in type 1 diabetes
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  19. The Role of Cytokines as Effectors of Tissue Destruction in Autoimmunity
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  20. NOD mice are functionally deficient in the capacity of cross‐presentation
    Chin‐Nien Lee, Andrew M. Lew, Ken Shortman, Li Wu · 2015 · Immunology and Cell Biology
  21. Animal Models in Biomedical Research
    Fred William Quimby · 2002 · Elsevier eBooks
  22. Beta cells in type 1 diabetes: victims or activators of t cell response?
    Charles H. Thivolet · 2002 · PubMed
  23. Image-Guided Analyses Reveal that Non-CD4 Splenocytes Contribute to CD4 + T Cell–Mediated Inflammation Leading to Islet Destruction by Altering Their Local Function and Not Systemic Trafficking Patterns
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  24. Expression of somatostatin receptor subtypes 1–5 in pancreatic islets of normoglycaemic and diabetic NOD mice
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  25. Counting the cost of proton pump inhibitors
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  26. Prevention of Type 1 Diabetes: Is Now the Time?1
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  27. Best practices in islet transplantation in mice.
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  28. Inibição da expressão de ciclooxigenase 2 em feridas cutâneas de camundongos NOD submetidos à terapia a laser de baixa intensidade
    Carolina de Lourdes Julião Vieira Rocha, Adeir Moreira Rocha Júnior, Beatriz Julião Vieira Aarestrup, Fernando Monteiro Aarestrup · 2012 · Jornal Vascular Brasileiro
  29. BTNL2‐Ig Protein Attenuates Type 1 Diabetes in Non‐Obese Diabetic (NOD) Mice
    Xiaohong Tian, Yujun Lin, Cheng Cui, Min Su, Laijun Lai · 2019 · Advanced Healthcare Materials
  30. The Potential Utility of Bone Marrow or Umbilical Cord Blood Transplantation For the Treatment of Type I Diabetes Mellitus
    Mohamed Mabed · 2010 · Transplantation and Cellular Therapy
  31. Animal Models to Study Adult Stem Cell-derived, In Vitro-generated Islet Implantation
    A. B. Peck, L. Yin, Vijayakumar K. Ramiya · 2004 · ILAR Journal
  32. Modelos experimentais para o estudo do diabetes tipo 1
    Vanessa Ramos Kirsten, Patrícia Sesterheim, David Saitovitch · 2010 · Medicina (Ribeirão Preto)
  33. Untitled work
    2000 · 10.1002/1520-7560(2000)9999:9999
  34. Distinct O -Acetylation Patterns of Serum Glycoproteins among Humans, Mice, and Rats
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  35. Humanized Mouse Models for Type 1 Diabetes Including Pancreatic Islet Transplantation
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  36. Correlation of Interleukin-10, Superoxide Dismutase (SOD), and Malondialdehyde (MDA) Levels with HbA1c in Pediatric Type 1 Diabetes Mellitus
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  37. Aberrant lipid accumulation in the mouse visceral yolk sac resulting from maternal diabetes and obesity
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  38. Induction of Active Tolerance and Involvement of CD1d-Restricted Natural Killer T Cells in Anti-CD3 F(ab′)2 Treatment-Reversed New-Onset Diabetes in Nonobese Diabetic Mice
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  39. Neuronal Elements in the Pathogenesis of Type 1 Diabetes
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  40. Adeno‐associated viral vectors for gene therapy
    Terence R. Flotte, Kenneth I. Berns · 2005 · Laboratory techniques in biochemistry and molecular biology
  41. Upregulation of Vascular ETB Receptor Gene Expression after Chronic ETA Receptor Blockade in Prediabetic NOD Mice
    Jana Ortmann, Tobias Traupe, Philipp Christoph Nett, Jennifer Celeiro, Regina Hofmann‐Lehmann, Melanie Lange, W. Vetter, Matthias Barton · 2004 · Journal of Cardiovascular Pharmacology
  42. Gastrointestinal Tract and Endocrine System
    Nonsikelelo Mpofu, Michelle A. Klose, Elmar Jäckel, Michael Peter Manns, Oliver P. Bachmann · 2013 · Springer eBooks
  43. Commentary: Modification of the Environment Is Not the Most Efficient Way to Prevent Type 1 Diabetes
    Norio Abiru, Liping Yu, MARIA JOSE REDONDO, George S. Eisenbarth · 2000 · Diabetes Technology & Therapeutics
  44. Altered monocyte cyclo-oxygenase response in non-obese diabetic mice
    Huriya Beyan, L. R. Buckley, Stephen Andrew Bustin, Nasim Yousaf, Paolo Pozzilli, R. D. G. Leslie · 2008 · Clinical & Experimental Immunology
  45. Effects of two pediatric vaccines on autoimmune diabetes in NOD female mice
    Guillaume Ravel · 2003 · Toxicology Letters
  46. Navigating diabetes-related immune epitope data: re-sources and tools provided by the Immune Epitope Da-tabase (IEDB)
    Kerrie C. Vaughan, Bjoern Peters · 2013 · Immunome Research
  47. Longitudinal Frequencies of Blood Leukocyte Subpopulations Differ between NOD and NOR Mice but Do Not Predict Diabetes in NOD Mice
    Tanja Telieps, Meike Köhler, Irina Treise, Katharina Foertsch, Thure Adler, Dirk Hans Busch, Martin Hrabě de Angelis, Admar Verschoor, Kerstin Adler, Ezio E. Bonifacio et al. · 2016 · Journal of Diabetes Research
  48. Anti-Diabetic Effect of Fruits on Different Animal Model System
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  49. Genetic Separation of the Transplantation Tolerance and Autoimmune Phenotypes in NOD Mice
    Todd Pearson, Thomas G. Markees, DAVID V. SERREZE, Melissa A. Pierce, Linda S. Wicker, Laurence B. Peterson, Leonard D. Shultz, John P. Mordes, Aldo A. Rossini, Dale L. Greiner · 2003 · Reviews in Endocrine and Metabolic Disorders
  50. Inhibition of the Proteasome Reduces Transfer‐Induced Diabetes in Nonobese Diabetic Mice
    Jelena Petrovic, H. Hall, Ramit Mehr, Rickard Glas, Petter Höglund · 2004 · Scandinavian Journal of Immunology
  51. Disease prevention with islet autoantigens
    George S. Eisenbarth, Jean Jasinski · 2004 · Endocrinology and Metabolism Clinics of North America
  52. Limited Effect of CpG ODN in Preventing Type 1 Diabetes in NOD Mice
    Byong Jun Lee, Soo Kie Kim, Moon Kyu Kim, Eon Sub Park, Hyun Chul Cho, Myung Sook Shim, Mi Jin Kim, Young Goo Shin, Choon Hee Chung · 2005 · Yonsei Medical Journal
  53. Type 1 diabetes intervention trials
    Massimo Pietropaolo, DOROTHY J. BECKER · 2001 · Pediatric Diabetes
  54. Nutrient Transporter Gene Expression in the Early Conceptus—Implications From Two Mouse Models of Diabetic Pregnancy
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  55. Antiproliferative and Pro-Oxidant Effect of Polyphenols in Aqueous Leaf Extract of Passiflora alata Curtis on Activated T Lymphocytes from Non-Obese Diabetic (NOD SHILT/J) Mice
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  56. Antibody combination therapy targeting CD25, CD70 and CD8 reduces islet inflammation and improves glycaemia in diabetic mice
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  57. Interleukin-1 Antagonism: A Sturdy Companion for Immune Tolerance Induction in Type 1 Diabetes?
    Thomas R Mandrup-Poulsen · 2014 · Diabetes
  58. Type 1 Diabetes Mellitus
    Huriya Beyan, R. D. G. Leslie · 2007 · Humana Press eBooks
  59. A Role for NF-κB and the Proteasome in Autoimmunity
    Takuma Hayashi, Denise Louise Faustman · 2001 · Springer eBooks
  60. Inverse vaccination with islet autoantigens to halt progression of autoimmune diabetes
    Simon A. Hinke · 2011 · Drug Development Research
  61. Glucose Homeostasis in Pre-diabetic NOD and Lymphocyte-Deficient NOD/SCID Mice During Gestation
    Josiane Coulaud, Sylvie Durant, Françoise Homo‐Delarche · 2010 · The Review of Diabetic Studies
  62. Fatal attraction: chemokines and type 1 diabetes
    Mark A. Atkinson, S. Brian Wilson · 2002 · Journal of Clinical Investigation
  63. Tolerance Induction and Endogenous Regeneration of Pancreatic β-Cells in Established Autoimmune Diabetes
    Charles Sia, Françoise Homo‐Delarche · 2004 · The Review of Diabetic Studies
  64. Rapid dissemination of RET-transgene-driven melanoma in the presence of non-obese diabetic alleles: Critical roles of Dectin-1 and Nitric-oxide synthase type 2
    Emna Dabbèche-Bouricha, Luiza M. M. Araujo, Masashi Kato, Armelle Prévost‐Blondel, Henri‐Jean Garchon · 2015 · OncoImmunology
  65. Diabetes Autoimmunity
    William E. Winter · 2006 · CRC Press eBooks
  66. Animal Models for Study of Diabetes Mellitus
    Agnesa Lukačínová, Beáta Hubková, Olivér Rácz, Ferenc Nistiar · 2013 · InTech eBooks
  67. Genetic Determinants of Virulence in the Group B Coxsackieviruses
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  68. Pathology of the Kidney in Diabetes
    Behzad Najafian, Charles E. Alpers · 2018 · Springer eBooks
  69. Manipulating the Type 1 Diabetes Disease Process, Man Versus Mouse
    Jerry P. Palmer · 2002 · Diabetes Care
  70. Elimination of T cell reactivity to pancreatic β cells and partial preservation of β cell activity by peptide blockade of LFA-1:ICAM-1 interaction in the NOD mouse model
    Abby L. Dotson, Lesya Novikova, Lisa Stehno‐Bittel, Stephen H. Benedict · 2013 · Clinical Immunology
  71. PD-1-dependent restoration of self-tolerance in the NOD mouse model of diabetes after transient anti-TCRβ mAb therapy
    Paul Michael Schroder, Mithun Khattar, Caitlin E. Baum, Yoshihiro Miyahara, Wenhao Chen, Rohit Vyas, Shravan Leonard‐Murali, Beata Mierzejewska, Stanislaw M. Stepkowski · 2015 · Diabetologia
  72. Future Outlook for Systems Biology
    Daniel L. Young, Seth Michelson · 2011 · Wiley eBooks
  73. Prevention of Autoimmune Disease: Type 1 Diabetes as a Paradigm
    Leonard C. Harrison · 2006 · Elsevier eBooks
  74. Alpha cells transdifferentiate into delta cells during the progression of autoimmunity in nondiabetic NOD mice
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  75. Humanized Mouse Models for Type 1 Diabetes
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  78. Association between proinflammatory cytokines and arterial stiffness in type 1 diabetic adolescents
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  80. Preclinical Trials for Stem Cell Therapy
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  81. Retardation of the Development of Diabetes Mellitus in a Murine Model of Type 1 Diabetes (NOD Mouse) Fed Morus alba Leaves.
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  82. Prediction and Prevention of Type 1 Diabetes
    Aristides K Maniatis, George S. Eisenbarth · 2003 · Humana Press eBooks
  83. Identification of a T1D Susceptibility Gene
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  86. DIABETOGENIC INFLUENCE OF HYPERDIET AND CYCLOPHOSPHAMIDE ON THE NON OBESE DIABETIC (NOD) MOUSE.
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  87. Animal Models of Type 1 Diabetes Mellitus
    Lucienne Chatenoud · 2007 · Humana Press eBooks
  88. Induction of Mixed Chimerism for Reversal of Autoimmunity in Type 1 Diabetes
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  89. Animal Models of Autoimmune Disease
    Matthias von Herrath, George C. Tsokos · 2006 · Elsevier eBooks
  90. Rational construction of controllable autoimmune diabetes model depicting clinical features
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  91. Central tolerance promoted by cell chimerism
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  93. Aetiology of Type 1 Diabetes Mellitus ‐ Genetics, Autoimmunity and Trigger Factors
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  95. Tissue engineering a pancreatic substitute based on recombinant intestinal endocrine cells
    Heather Bara · 2008 · SMARTech Repository (Georgia Institute of Technology)
  96. Questioning Four Preconceived Ideas on Immunotherapy of Clinical Type 1 Diabetes: Lessons from Recent CD3 Antibody Trials
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  97. Impaired vascular function in normoglycemic mice prone to autoimmune diabetes: Role of nitric oxide
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  98. Tissue Factor as a Link Between Wounding and Tissue
    Repair Chen, Michael E. Kasper, Tobias Heck, Katsumi Nakagawa, Per M. Humpert, Ling Bai, Gang Quan Wu, Youming Zhang, Thomas Luther, Martin Andrassy et al. · 2005
  99. Adiponectin and immune tolerance in type 1 diabetes
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  100. Autoimmune Type 1 Diabetes
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